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MXRA8 Gene

protein-coding GIFtS: 46
GCID: GC01M001278

Matrix-Remodelling Associated 8

See related diseases
at

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(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, ¹⁰fRNAdb, ¹²H-InvDB, ¹³NCBI, ¹⁴NONCODE, and/or ¹⁵RNAdb)
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This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Matrix-Remodelling Associated 8¹ ²
limitrin¹ ²
Matrix-Remodeling-Associated Protein 8²
Limitrin³

External Ids:	HGNC: 7542¹	Entrez Gene: 54587²	Ensembl: ENSG00000162576⁷	UniProtKB: Q9BRK3³

ORGUL members:

Export aliases for MXRA8 gene to outside databases

Previous GC identifers: GC00U990744 GC01U901165 GC01M000561

(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for MXRA8 Gene:

MXRA8 (matrix-remodelling associated 8) is a protein-coding gene. Diseases associated with MXRA8 include tonsillitis, and cerebritis.

UniProtKB/Swiss-Prot: MXRA8_HUMAN, Q9BRK3

Function: May play a role in the maturation and maintenance of blood-brain barrier (By similarity)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:

NC_000001.11 NT_032977.10 NC_018912.2

Regulatory elements:

Regulatory transcription factor binding sites in the MXRA8 gene promoter:
PPAR-gamma1 PPAR-gamma2 C/EBPalpha
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: MXRA8 promoter sequence

Search Chromatin IP Primers for MXRA8

Epigenetics:

DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MXRA8

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p36.33 Ensembl cytogenetic band: 1p36.33 HGNC cytogenetic band: 1p36.33

MXRA8 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MXRA8 gene location

GeneLoc information about chromosome 1 GeneLoc Exon Structure

GeneLoc location for GC01M001278: view genomic region (about GC identifiers)

Start:	1,288,069 bp from pter	End:	1,297,157 bp from pter
Size:	9,089 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, ²neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: MXRA8_HUMAN, Q9BRK3 (See protein sequence)

Recommended Name: Matrix-remodeling-associated protein 8 precursor

Size: 442 amino acids; 49132 Da

Secondary accessions: Q5TA39 Q96KC3

Alternative splicing: 2 isoforms: Q9BRK3-1 Q9BRK3-2

Explore the universe of human proteins at neXtProt for MXRA8: NX_Q9BRK3

Explore proteomics data for MXRA8 at MOPED

Post-translational modifications:

Glycosylation² at Asn119, Asn306

Modification sites at PhosphoSitePlus

See MXRA8 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins (5 alternative transcripts):

NP_001269511.1 NP_001269512.1 NP_001269513.1 NP_001269514.1 NP_115724.1

ENSEMBL proteins:

ENSP00000307887 ENSP00000399229 ENSP00000436135 ENSP00000344998

MXRA8 Human Recombinant Protein Products:

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MXRA8 Antibody Products:

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	Cloud-Clone Corp. Antibodies for MXRA8
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	Search LSBio for Antibodies for MXRA8

MXRA8 Assay Products:

	Browse Kits and Assays available from EMD Millipore
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	Cloud-Clone Corp. ELISAs for MXRA8 Cloud-Clone Corp. CLIAs for MXRA8

(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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HGNC Gene Families:

VSET: Immunoglobulin superfamily / V-set domain containing

4 InterPro protein domains:

IPR013783 Ig-like_fold

IPR013106 Ig_V-set

IPR007110 Ig-like_dom

IPR003599 Ig_sub

Graphical View of Domain Structure for InterPro Entry Q9BRK3

ProtoNet protein and cluster: Q9BRK3

1 Blocks protein domain: IPB013106 Immunoglobulin V-set

UniProtKB/Swiss-Prot: MXRA8_HUMAN, Q9BRK3

Similarity: Contains 2 Ig-like V-type (immunoglobulin-like) domains

MXRA8 for domains About GeneDecksing

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

UniProtKB/Swiss-Prot Summary: MXRA8_HUMAN, Q9BRK3

Function: May play a role in the maturation and maintenance of blood-brain barrier (By similarity)

Gene Ontology (GO): 2 molecular function terms: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003674	molecular_function	ND	--
GO:0005515	protein binding	--	--

MXRA8 for ontologies About GeneDecksing

Phenotypes:
1 MGI mutant phenotype (inferred from 1 allele) (MGI details for Mxra8):

normal

MXRA8 for phenotypes About GeneDecksing

Animal Models:

inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for MXRA8

inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for MXRA8

genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for MXRA8

genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for MXRA8

miRNA Products:		miRTarBase miRNAs that target MXRA8: hsa-mir-335-5p (MIRT018682)

		Block miRNA regulation of human, mouse, rat MXRA8 using miScript Target Protectors
		6 qRT-PCR Assays for microRNAs that regulate MXRA8:
		hsa-miR-125a-5p hsa-miR-125b hsa-miR-548c-3p hsa-miR-3157-5p hsa-miR-766 hsa-miR-4319
		SwitchGear 3'UTR luciferase reporter plasmid: MXRA8 3' UTR sequence

Inhib. RNA Products:		OriGene RNAi products in human, mouse, rat for MXRA8
		Predesigned siRNA for gene silencing in human, mouse, rat MXRA8

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for MXRA8

Clone Products:		OriGene clones in human, mouse for MXRA8 (see all 7) OriGene ORF clones in mouse, rat for MXRA8 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: MXRA8 (NM_032348)
		Sino Biological Human cDNA Clone for MXRA8
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for MXRA8
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MXRA8

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for MXRA8
		Browse ESI BIO Cell Lines and PureStem Progenitors for MXRA8

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MXRA8

(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot

MXRA8_HUMAN, Q9BRK3: Membrane; Single-pass type I membrane protein

Subcellular locations from COMPARTMENTS:

Compartment	Confidence
mitochondrion	2
plasma membrane	2
endoplasmic reticulum	1
extracellular	1
peroxisome	1

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Gene Ontology (GO): 3 cellular component terms: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0009986	cell surface	ISS	14603461
GO:0016021	integral component of membrane	IEA	--
GO:0070062	extracellular vesicular exosome	IDA	19056867

MXRA8 for ontologies About GeneDecksing

(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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Custom Pathway & Disease-focused RT² Profiler PCR Arrays for MXRA8
Interactions:

Search GeneGlobe Interaction Network for MXRA8

STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

3 Interacting proteins for MXRA8 (Q9BRK3³ ENSP00000307887⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
SLC2A4	P14672³	I2D: score=1
WNK1	Q9H4A3³	I2D: score=1
OPTC	ENSP00000356191⁴	STRING: ENSP00000356191

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Gene Ontology (GO): 1 biological process term: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0060857	establishment of glial blood-brain barrier	ISS	14603461

MXRA8 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse compounds at ApexBio

Browse Tocris compounds for MXRA8

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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REFSEQ mRNAs for MXRA8 gene (5 alternative transcripts):

NM_001282582.1 NM_001282583.1 NM_001282584.1 NM_001282585.1 NM_032348.3

Unigene Cluster for MXRA8:

Matrix-remodelling associated 8

Hs.515687 [show with all ESTs]

Unigene Representative Sequence: AK095966

10 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000474033 ENST00000309212(uc001aew.3 uc001aey.4 uc001aez.3)

ENST00000445648(uc001aex.4) ENST00000477278(uc001afa.3) ENST00000473097

ENST00000478517 ENST00000476718 ENST00000464351 ENST00000460473 ENST00000342753

miRNA Products:		Block miRNA regulation of human, mouse, rat MXRA8 using miScript Target Protectors
		6 qRT-PCR Assays for microRNAs that regulate MXRA8:
		hsa-miR-125a-5p hsa-miR-125b hsa-miR-548c-3p hsa-miR-3157-5p hsa-miR-766 hsa-miR-4319
		SwitchGear 3'UTR luciferase reporter plasmid: MXRA8 3' UTR sequence

Inhib. RNA Products:		OriGene RNAi products in human, mouse, rat for MXRA8
		Predesigned siRNA for gene silencing in human, mouse, rat MXRA8

Clone Products:		OriGene clones in human, mouse for MXRA8 (see all 7) OriGene ORF clones in mouse, rat for MXRA8 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: MXRA8 (NM_032348)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for MXRA8
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MXRA8

Primer Products:		OriGene qPCR primer pairs and template standards for MXRA8 OriGene qSTAR qPCR primer pairs in human, mouse for MXRA8
		Pre-validated RT² qPCR Primer Assay in human, mouse, rat MXRA8
		QuantiTect SYBR Green Assays in human, mouse, rat MXRA8
		QuantiFast Probe-based Assays in human, mouse, rat MXRA8

Additional mRNA sequence:

AB052096.1 AK027269.1 AK095966.1 AK225028.1 AK293442.1 AK304615.1 AK315510.1 AL050202.1

AY358391.1 BC006213.2 BC017312.2

14 DOTS entries:

DT.101983679 DT.95223113 DT.444857 DT.121333040 DT.97846475 DT.100786102 DT.100060876 DT.121333029

DT.121333042 DT.92332531 DT.95284120 DT.121333054 DT.95268902 DT.95351662

GeneLoc Exon Structure

5 Alternative Splicing Database (ASD) splice patterns (SP) for MXRA8 About this scheme

ExUns:	1	^	2	^	3a	·	3b	^	4	^	5a	·	5b	·	5c	^	6	^	7	^	8	^	9a	·	9b	^	10a	·	10b
SP1:
SP2:
SP3:																							-		-
SP4:
SP5:

ECgene alternative splicing isoforms for MXRA8

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE ¹MOPED, ²PaxDb, and ³MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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MXRA8 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>^2/3
CGAP TAG: TGGGACTCCA

About this image

MXRA8 expression in embryonic tissues and stem cells About this table

Data from LifeMap, the Embryonic Development and Stem Cells Database
selected tissues (see all 12) fully expand


Brain (Nervous System) fully expand to see all 4 entries
Cerebral Cortex

Heart (Cardiovascular System) fully expand to see all 2 entries
Semilunar Valves

Ovary (Reproductive System)
Oviduct

Bone (Muscoskeletal System)
Rib

Testis (Reproductive System)
Leydig Cells Testis Interstitium

MXRA8 Protein expression data from MOPED¹, PaxDb² and MaxQB³:

About this image

MXRA8 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.515687

Custom PCR Arrays for MXRA8

Primer Products:		OriGene qPCR primer pairs and template standards for MXRA8 OriGene qSTAR qPCR primer pairs in human, mouse for MXRA8
		Pre-validated RT² qPCR Primer Assay in human, mouse, rat MXRA8
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		QuantiFast Probe-based Assays in human, mouse, rat MXRA8

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MXRA8

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of chordates.

Orthologs for MXRA8 gene from Selected species (see all 10) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Mxra8^{1 , 5}	matrix-remodelling associated 8^{1, 5}	78.08(n)¹ 78.46(a)¹		4 (87.58 cM)⁵ 74761¹ NM_024263.4¹ NP_077225.4¹ 155839680⁵
chicken (Gallus gallus)	Aves	MXRA8¹	matrix-remodelling associated 8	64.21(n) 61.06(a)		395347 NM_204636.2 NP_989967.1
lizard (Anolis carolinensis)	Reptilia	MXRA8⁶	matrix-remodelling associated 8	56(a)	1 ↔ 1	GL343701.1(1897-23970)
tropical clawed frog (Xenopus tropicalis)	Amphibia	mxra8¹	matrix-remodelling associated 8	57.64(n) 53.7(a)		100101754 NM_001122725.1 NP_001116197.1
zebrafish (Danio rerio)	Actinopterygii	mxra8a¹	matrix-remodelling associated 8a	56.5(n) 51.42(a)		562784 NM_001080582.1 NP_001074051.1

ENSEMBL Gene Tree for MXRA8 (if available)
TreeFam Gene Tree for MXRA8 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
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(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, ⁴UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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SNP ID	Valid	Clinical significance	Chr 1 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs181712123^1,2		--	1287588(+)	`CTGCAC/GCCAAC`	1	--	int¹		0	--	--	--	--
rs140688425^1,2		--	1287635(+)	`GATCCA/GTGCTG`	1	--	int¹		0	--	--	--	--
rs145678879^1,2	C	--	1287732(+)	`GACCCA/GCATCC`	1	--	int¹		0	--	--	--	--
rs186076320^1,2		--	1287748(+)	`CTCCCA/GCTCCT`	1	--	int¹		0	--	--	--	--
rs138337614^1,2	C	--	1287755(+)	`TCCTCA/GTCCCT`	1	--	int¹		0	--	--	--	--
rs190450833^1,2		--	1287896(+)	`ACTAGC/GTCAAA`	1	--	int¹		0	--	--	--	--
rs3766185^1,2	C	--	1287922(-)	`GGAGTT/CGGTGT`	1	--	int¹		9		EA NA WA CSA	1508
rs143240591^1,2		--	1287964(+)	`AGGAAC/TGGGAT`	1	--	int¹		0	--	--	--	--
rs148049883^1,2	C	--	1287973(+)	`ATGATA/GTCAGG`	1	--	int¹		0	--	--	--	--
rs35481025^1,2	C,F	--	1288042(-)	`AAACTC/TCGTCT`	1	--	int¹		2		NA CSA	6

HapMap Linkage Disequilibrium report for MXRA8 (1288069 - 1297157 bp)

Structural Variations
Database of Genomic Variants (DGV) Selected variations for MXRA8 (see all 25): About this table

Variant ID	Type	Subtype	PubMed ID
dgv17n71	CNV	Loss	21882294
nsv470680	CNV	Loss	18288195
nsv870639	CNV	Loss	21882294
dgv29n71	CNV	Loss	21882294
nsv482937	CNV	Loss	15286789
dgv39n71	CNV	Loss	21882294
dgv12n71	CNV	Loss	21882294
dgv25n71	CNV	Loss	21882294
dgv19n71	CNV	Loss	21882294
nsv870491	CNV	Loss	21882294

Site Specific Mutation Identification with PCR Assays

SeqTarget long-range PCR primers for resequencing MXRA8

DNA2.0 Custom Variant and Variant Library Synthesis for MXRA8

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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3 diseases for MXRA8:
About MalaCards

tonsillitis cerebritis thyroiditis

MXRA8 for disorders About GeneDecksing

Export disorders for MXRA8 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for MXRA8 gene, integrated from 10 sources (see all 11):
(articles sorted by number of sources associating them with MXRA8)

Utopia: connect your pdf to the dynamic
world of online information

Limitrin, a novel immunoglobulin superfamily protein localized to glia limitans formed by astrocyte endfeet. (PubMed id 14603461)^{1, 2, 3} Yonezawa T.... Ninomiya Y. (Glia 2003)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (Nat. Genet. 2004)
DICAM inhibits angiogenesis via suppression of AKT and p38 MAP kinase signalling. (PubMed id 23386276)¹ Han S.W....Choi J.Y. (Cardiovasc. Res. 2013)
Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)¹ Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
The BTB and CNC homology 1 (BACH1) target genes are involved in the oxidative stress response and in control of the cell cycle. (PubMed id 21555518)¹ Warnatz H.J....Yaspo M.L. (J. Biol. Chem. 2011)
Large-scale proteomics and phosphoproteomics of urinary exosomes. (PubMed id 19056867)¹ Gonzales P.A....Knepper M.A. (J. Am. Soc. Nephrol. 2009)
The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)² Gregory S.G.... Bentley D.R. (Nature 2006)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)² Gerhard D.S.... Malek J. (Genome Res. 2004)
The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)¹ Clark H.F.... Gray A.M. (Genome Res. 2003)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 54587	HGNC: 7542	Ensembl:ENSG00000162576	euGenes: HUgn54587	ECgene: MXRA8
H-InvDB: MXRA8

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for MXRA8	Pharmacogenomics, SNPs, Pathways

Intellectual Property for MXRA8 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for MXRA8 gene:
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(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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MXRA8 Gene

Matrix-Remodelling Associated 8

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MXRA8 Gene

Matrix-Remodelling Associated 8

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