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Aliases for MXRA7 Gene

Aliases for MXRA7 Gene

  • Matrix Remodeling Associated 7 2 3 5
  • Matrix-Remodelling Associated 7 2 3
  • Transmembrane Anchor Protein 1 3 4
  • TMAP1 3 4
  • Matrix-Remodeling-Associated Protein 7 3
  • HBV PreS1-Transactivated Protein 1 3
  • PS1TP1 3

External Ids for MXRA7 Gene

Previous GeneCards Identifiers for MXRA7 Gene

  • GC00U990745
  • GC17M072187
  • GC17M074671
  • GC17M070099

Summaries for MXRA7 Gene

GeneCards Summary for MXRA7 Gene

MXRA7 (Matrix Remodeling Associated 7) is a Protein Coding gene. Diseases associated with MXRA7 include Endometriosis Of Ovary.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MXRA7 Gene

Genomics for MXRA7 Gene

Regulatory Elements for MXRA7 Gene

Enhancers for MXRA7 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH17F076686 1.4 Ensembl ENCODE 70.3 +22.8 22825 3.3 ATF1 MLX ARID4B FEZF1 DMAP1 ZNF48 SLC30A9 GLIS2 FOS SP5 MXRA7 JMJD6 RNU6-227P METTL23 PRCD CYGB UBE2O AANAT RNU6-97P GC17M076685
GH17F076681 0.9 Ensembl ENCODE 62.1 +28.2 28182 3.7 CBX3 ARID4B ZNF48 RAD21 ZNF143 CREM EGR2 THAP11 ZNF263 KLF11 MXRA7 RNU6-227P METTL23 JMJD6 GC17M076685 GC17M076671
GH17F076694 1.2 FANTOM5 Ensembl ENCODE 51.8 +12.2 12201 8.0 ARNT MLX ARID4B FEZF1 DMAP1 ZNF2 SLC30A9 ZNF143 FOS ZNF548 MXRA7 UNK METTL23 ENSG00000266980 RNU6-227P JMJD6 MFSD11 PRCD TRIM65 ENSG00000267546
GH17F076707 1.2 FANTOM5 ENCODE 48.5 +1.3 1308 4.6 PKNOX1 ZFP64 ARID4B SIN3A ZNF48 ZNF121 GLIS2 ZNF143 FOS PAF1 MXRA7 RNU6-227P PRCD CYGB ENSG00000277382 GC17M076710 RNY4P36
GH17F076677 1.2 Ensembl ENCODE 45.3 +32.3 32315 1.8 BCOR SOX13 SOX5 SAP130 ZNF133 GATA2 POLR2A ZNF600 MXRA7 RNU6-227P TRIM47 GC17M076671 GC17M076685
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MXRA7 on UCSC Golden Path with GeneCards custom track

Promoters for MXRA7 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001810075 816 2001 PKNOX1 SIN3A ZNF121 GLIS2 FOS ZNF263 SP3 YY2 SP5 SMARCA4

Genomic Location for MXRA7 Gene

Chromosome:
17
Start:
76,672,551 bp from pter
End:
76,711,016 bp from pter
Size:
38,466 bases
Orientation:
Minus strand

Genomic View for MXRA7 Gene

Genes around MXRA7 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MXRA7 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MXRA7 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MXRA7 Gene

Proteins for MXRA7 Gene

  • Protein details for MXRA7 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P84157-MXRA7_HUMAN
    Recommended name:
    Matrix-remodeling-associated protein 7
    Protein Accession:
    P84157
    Secondary Accessions:
    • Q0P5W3

    Protein attributes for MXRA7 Gene

    Size:
    204 amino acids
    Molecular mass:
    21466 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AW888225; Type=Frameshift; Positions=Several; Evidence={ECO:0000305};

    Alternative splice isoforms for MXRA7 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for MXRA7 Gene

Post-translational modifications for MXRA7 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for MXRA7 Gene

Domains & Families for MXRA7 Gene

Protein Domains for MXRA7 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for MXRA7 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MXRA7: view

No data available for Gene Families and UniProtKB/Swiss-Prot for MXRA7 Gene

Function for MXRA7 Gene

Phenotypes for MXRA7 Gene

genes like me logo Genes that share phenotypes with MXRA7: view

Animal Model Products

  • Taconic Biosciences Mouse Models for MXRA7

miRNA for MXRA7 Gene

miRTarBase miRNAs that target MXRA7

Inhibitory RNA Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for MXRA7 Gene

Localization for MXRA7 Gene

Subcellular locations from UniProtKB/Swiss-Prot for MXRA7 Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for MXRA7 Gene COMPARTMENTS Subcellular localization image for MXRA7 gene
Compartment Confidence
endoplasmic reticulum 3
extracellular 3
nucleus 1

Gene Ontology (GO) - Cellular Components for MXRA7 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with MXRA7: view

Pathways & Interactions for MXRA7 Gene

SuperPathways for MXRA7 Gene

No Data Available

Interacting Proteins for MXRA7 Gene

Gene Ontology (GO) - Biological Process for MXRA7 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MXRA7 Gene

Transcripts for MXRA7 Gene

Unigene Clusters for MXRA7 Gene

Matrix-remodelling associated 7:
Representative Sequences:

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MXRA7 Gene

No ASD Table

Relevant External Links for MXRA7 Gene

GeneLoc Exon Structure for
MXRA7
ECgene alternative splicing isoforms for
MXRA7

Expression for MXRA7 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MXRA7 Gene

Protein differential expression in normal tissues from HIPED for MXRA7 Gene

This gene is overexpressed in Bone (10.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for MXRA7 Gene



Protein tissue co-expression partners for MXRA7 Gene

NURSA nuclear receptor signaling pathways regulating expression of MXRA7 Gene:

MXRA7

SOURCE GeneReport for Unigene cluster for MXRA7 Gene:

Hs.250723
genes like me logo Genes that share expression patterns with MXRA7: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for MXRA7 Gene

Orthologs for MXRA7 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MXRA7 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia MXRA7 34 35
  • 99.67 (n)
mouse
(Mus musculus)
Mammalia Mxra7 35
  • 63 (a)
OneToOne
chicken
(Gallus gallus)
Aves MXRA7 35
  • 45 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii mxra7 35
  • 32 (a)
OneToOne
Species where no ortholog for MXRA7 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MXRA7 Gene

ENSEMBL:
Gene Tree for MXRA7 (if available)
TreeFam:
Gene Tree for MXRA7 (if available)

Paralogs for MXRA7 Gene

No data available for Paralogs for MXRA7 Gene

Variants for MXRA7 Gene

Sequence variations from dbSNP and Humsavar for MXRA7 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type
rs1005644 -- 76,701,304(-) CGCCT(C/T)CCTCA intron-variant
rs1005645 -- 76,700,678(-) GCCAC(A/G)TCCCA intron-variant
rs1017096 -- 76,702,738(-) AATAG(C/T)TGGGA intron-variant
rs1034929 -- 76,684,041(-) GTGGG(G/T)GGCGG intron-variant
rs10459886 -- 76,701,094(+) CGGGG(G/T)GTGTG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for MXRA7 Gene

Variant ID Type Subtype PubMed ID
esv2190268 CNV deletion 18987734
esv2426649 CNV deletion 19546169
esv2716258 CNV deletion 23290073
esv2716259 CNV deletion 23290073
esv2716260 CNV deletion 23290073
esv2716261 CNV deletion 23290073
esv28006 CNV gain 19812545
nsv111859 CNV insertion 16902084
nsv1121528 CNV deletion 24896259
nsv1134678 CNV deletion 24896259
nsv828109 CNV gain 20364138
nsv960533 CNV duplication 23825009

Variation tolerance for MXRA7 Gene

Gene Damage Index Score: 12.69; 94.62% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for MXRA7 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MXRA7

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MXRA7 Gene

Disorders for MXRA7 Gene

MalaCards: The human disease database

(1) MalaCards diseases for MXRA7 Gene - From: DISEASES

Disorder Aliases PubMed IDs
endometriosis of ovary
  • ovarian endometriosis
- elite association - COSMIC cancer census association via MalaCards
Search MXRA7 in MalaCards View complete list of genes associated with diseases

Relevant External Links for MXRA7

Genetic Association Database (GAD)
MXRA7
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MXRA7
genes like me logo Genes that share disorders with MXRA7: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MXRA7 Gene

Publications for MXRA7 Gene

  1. DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PMID: 16625196) Zody M.C. … Nusbaum C. (Nature 2006) 3 4 64
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  3. Genetic loci for retinal arteriolar microcirculation. (PMID: 23776548) Sim X. … Wong T.Y. (PLoS ONE 2013) 3 64
  4. Toward a comprehensive characterization of a human cancer cell phosphoproteome. (PMID: 23186163) Zhou H. … Mohammed S. (J. Proteome Res. 2013) 4 64
  5. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. (PMID: 22658674) Castello A. … Hentze M.W. (Cell 2012) 3 64

Products for MXRA7 Gene

Sources for MXRA7 Gene

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