Aliases for MVD Gene
External Ids for MVD Gene
Previous GeneCards Identifiers for MVD Gene
The enzyme mevalonate pyrophosphate decarboxylase catalyzes the conversion of mevalonate pyrophosphate into isopentenyl pyrophosphate in one of the early steps in cholesterol biosynthesis. It decarboxylates and dehydrates its substrate while hydrolyzing ATP. [provided by RefSeq, Jul 2008]
GeneCards Summary for MVD Gene
MVD (Mevalonate (Diphospho) Decarboxylase) is a Protein Coding gene. Diseases associated with MVD include waterhouse-friderichsen syndrome. Among its related pathways are Regulation of Cholesterol Biosynthesis by SREBP (SREBF) and Regulation of Cholesterol Biosynthesis by SREBP (SREBF). GO annotations related to this gene include protein homodimerization activity and diphosphomevalonate decarboxylase activity.
UniProtKB/Swiss-Prot for MVD Gene
Performs the first committed step in the biosynthesis of isoprenes