MVD Gene
protein-coding GIFtS: 60
GCID: GC16M088718
|
|
mevalonate (diphospho) decarboxylase
| |
Aliases
for MVD gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Mevalonate (Diphospho) Decarboxylase1 2 | | FP177802 | | MPD1 2 3 | | Diphosphomevalonate Decarboxylase2 | | Mevalonate Pyrophosphate Decarboxylase2 3 | | EC 4.1.1.333 | | MDDase2 3 | | Mevalonate (Diphospho)Decarboxylase3 |
Export aliases for MVD gene to outside databasesPrevious GC identifers: GC16M080154 GC16M089686 GC16M088421 GC16M088462 GC16M087245 GC16M074412 |
Summaries
for MVD gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for MVD:
The enzyme mevalonate pyrophosphate decarboxylase catalyzes the conversion of mevalonate pyrophosphate into isopentenylpyrophosphate in one of the early steps in cholesterol biosynthesis. It decarboxylates and dehydrates its substratewhile hydrolyzing ATP. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: MVD1_HUMAN, P53602Function: Performs the first committed step in the biosynthesis of isoprenes
|
Genomic Views
for MVD gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000016.9 NC_018927.1 NT_010542.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the MVD gene promoter:
AhR PPAR-alpha Pax-5 Sp1 AP-1 p53 Arnt
Other transcription factors
Search SABiosciences Chromatin IP Primers for MVD
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MVD |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 16q24.3 Ensembl cytogenetic band: 16q24.3 HGNC cytogenetic band: 16q24.3MVD Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 16 GeneLoc Exon Structure GeneLoc location for GC16M088718: view genomic region
(about GC identifiers)
Start:
|
88,718,343 bp from pter |
End:
|
88,729,569 bp from pter |
Size:
|
11,227 bases |
Orientation:
|
minus strand |
|
Proteins
for MVD gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: MVD1_HUMAN, P53602 (See
protein sequence)Recommended Name: Diphosphomevalonate decarboxylase Size: 400 amino acids; 43405 Da
Subunit: Homodimer
1 PDB 3D structure from  and Proteopedia  for MVD:3D4J (3D)
Secondary accessions: Q53Y65Explore the universe of human proteins at neXtProt for MVD: NX_P53602
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P53602
MVD Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_002452.1
ENSEMBL proteins: ENSP00000301012 ENSP00000455131 ENSP00000458049 ENSP00000455602 ENSP00000456465 Reactome Protein details: P53602
Human Recombinant Protein Products:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
MVD for ontologies About GeneDecksing
MVD Antibody Products:
Assay Products for MVD: |
Protein
Domains /
Families
for MVD gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
MVD for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P53602ProtoNet protein and cluster: P53602 UniProtKB/Swiss-Prot: MVD1_HUMAN, P53602Similarity: Belongs to the diphosphomevalonate decarboxylase family |
Function
for MVD gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: MVD1_HUMAN, P53602Function: Performs the first committed step in the biosynthesis of isoprenesCatalytic activity: ATP + (R)-5-diphosphomevalonate = ADP + phosphate + isopentenyl diphosphate + CO(2)Biophysicochemical properties: Kinetic parameters: KM=7.4 uM for (R)-5-diphosphomevalonate; KM=0.32 mM for ATP;Enzyme Number (IUBMB): EC 4.1.1.331
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MVD (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MVD
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: MVD (NM_002461) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MVD | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MVD |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MVD |
Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view): About this table
MVD for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for MVD:
Animal Models:
1 MGI phenotypic allele  for Mvd (no phenotypes)
MVD for phenotypes About GeneDecksing
|
Pathways & Interactions
for MVD gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Regulation of Cholesterol Biosynthesis by SREBP (SREBF) | | | 2 | Metabolism | | | 3 | superpathway of geranylgeranyldiphosphate biosynthesis I (via mevalonate) | | | 4 | Cholesterol biosynthesis | | | 5 | Expression of ELOVL6 | |
Pathway sources
See GeneCards unified pathways
Show all pathways
5  BioSystems Pathways for MVD
5/6 
Reactome Pathways for MVD (see all 6)
2 
Kegg Pathways (Kegg details for MVD):
UniProtKB/Swiss-Prot: MVD1_HUMAN, P53602Pathway: Steroid biosynthesis; cholesterol biosynthesis
MVD for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for MVD
STRING Interaction
Network Preview (showing 5 interactants - click image to see 18)
5/83 Interacting proteins for MVD (P536022, 3 ENSP000003010124) via UniProtKB, MINT, STRING, and/or I2D (see all 83)
About this table
Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6): About this table
MVD for ontologies About GeneDecksing
|
Drugs & Compounds
for MVD gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
MVD for compounds About GeneDecksing
 Browse Tocris compounds for MVD
7 HMDB Compounds for MVD About this table
8 Novoseek chemical compound relationships for MVD gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| mevalonate pyrophosphate |
98.2 |
18 |
14972328 (3), 8626466 (2), 7947744 (2), 9600263 (1) (see all 9) |
| 6-fluoromevalonate |
95.4 |
4 |
7712482 (1), 9270019 (1) |
| phosphomevalonate |
93.2 |
3 |
14680974 (1), 11188689 (1), 19485344 (1) |
| mevalonate |
83.7 |
9 |
7712482 (1), 9270019 (1), 14680974 (1), 11188689 (1) (see all 7) |
| isopentenyl diphosphate |
81.9 |
1 |
14680974 (1) |
| lovastatin |
76.4 |
4 |
9270019 (1), 9600263 (1), 15166627 (1) |
| sterol |
52.3 |
1 |
10344201 (1) |
| cholesterol |
34 |
3 |
8626466 (1), 15166627 (1), 15994924 (1) |
Search CenterWatch for drugs/clinical trials and news about MVD / MVD1
|
Transcripts
for MVD gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for MVD gene: NM_002461.1 Unigene Cluster for MVD: Mevalonate (diphospho) decarboxylase Hs.252457 [show with all ESTs]Unigene Representative Sequence: AB20922917 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000565149(uc002flf.1) ENST00000301012(uc002flg.1) ENST00000562981
ENST00000561895 ENST00000569177 ENST00000567064 ENST00000568133 ENST00000563785
ENST00000568709 ENST00000563170 ENST00000566636 ENST00000565720 ENST00000562651
ENST00000565610 ENST00000563463 ENST00000562741 ENST00000565842
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MVD (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MVD
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: MVD (NM_002461) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MVD | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MVD |
Additional cDNA sequence: AB209229.1 AY203927.1 BC000011.2 BT006930.1 U49260.1 14 DOTS entries: DT.87016603 DT.75135260 DT.95087273 DT.100807303 DT.97847795 DT.95151588 DT.95151587 DT.101975975 DT.95151590 DT.100807305 DT.100807311 DT.102830477 DT.120668778 DT.120668799 24/268 AceView cDNA sequences (see all 268): BM904107 AW075275 BU539564 BU538505 T09119 BQ710385 BM910669 AW103760 BF589947 CD674084 BF058316 AI201391 BX458350 CA775934 BI759022 BQ641769 BX340321 BI825999 AI658536 BQ956062 AI864951 BM823763 AI336835 BX331219
GeneLoc Exon Structure
5/20 Alternative Splicing Database (ASD) splice patterns (SP) for MVD (see all 20) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | · | 1f | ^ | 2a | · | 2b | ^ | 3a | · | 3b | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7 | ^ | 8a | · | 8b | ^ | 9a | · | 9b | · | 9c | ^ | 10 | ^ | 11 | ^ | 12a | · | 12b | · | 12c | ^ | 13a | · |
|---|
|
| SP1: | | | | | | | | | | | | | - | | - | | - | | - | | - | | - | | - | | | | | | | | - | | - | | | | | | - | | - | | - | | | | | | | | |
| SP2: | | | | | | | | | | | | | - | | - | | - | | | | | | - | | - | | | | | | | | - | | - | | | | | | - | | - | | - | | | | | | | | |
| SP3: | | | | | | | | | | | | | - | | - | | - | | - | | - | | - | | - | | | | | | | | - | | - | | | | | | | | - | | - | | | | | | | | |
| SP4: | | | | | | | | | | | | | - | | | | - | | - | | - | | - | | - | | | | | | | | - | | - | | | | | | - | | - | | - | | | | | | | | |
| SP5: | | | | | | | | | | | | | - | | - | | - | | | | | | - | | - | | | | | | | | - | | - | | | | | | - | | - | | - | | | | | | | |
| ExUns: | 13b | · | 13c | ^ | 14a | · | 14b | ^ | 15a | · | 15b | · | 15c | ^ | 16 | ^ | 17a | · | 17b | ^ | 18 |
|---|
|
| SP1: | | | - | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | - | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | - | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | - | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for MVD
|
Expression
for MVD gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| MVD expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GGGAATAAAC
About this image
See MVD Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for MVD
SOURCE GeneReport for Unigene cluster: Hs.252457
UniProtKB/Swiss-Prot: MVD1_HUMAN, P53602Tissue specificity: Expressed in heart, skeletal muscle, lung, liver, brain, pancreas, kidney and placenta
SABiosciences Expression via Pathway-Focused PCR Array including MVD: | Lipoprotein Signaling & Cholesterol Metabolism in human mouse rat |
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MVD
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat MVD | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MVD | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MVD | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MVD |
Orthologs
for MVD gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for MVD gene from 10/34 species (see all 34) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Mvd1 , 5 |
mevalonate (diphospho) decarboxylase1, 5 |
82.7(n)1
84.63(a)1 |
|
8 (71.05 cM)5
1921561 NM_138656.21 NP_619597.21
1224335965 |
chicken
(Gallus gallus) |
Aves |
MVD1 |
mevalonate (diphospho) decarboxylase |
73.35(n)
72.34(a) |
|
425359 XM_423130.3 XP_423130.3 |
lizard
(Anolis carolinensis) |
Reptilia |
MVD6 |
-- |
68(a) |
1 ↔ 1 |
GL343670.1(114376-128760) |
tropical clawed frog
(Xenopus tropicalis) |
Amphibia |
LOC3948712 |
hypothetical protein LOC394871 |
75.54(n) |
|
BC063907.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
zgc:1008241 |
zgc:100824 |
65.47(n)
67.52(a) |
|
492781 NM_001007422.1 NP_001007423.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG82391 , 3 |
diphosphomevalonate decarboxylase3
CG82391 |
48(a)3
54.27(n)1
50.66(a)1 |
|
13E143
325201 NM_132840.41 NP_573068.31 |
worm
(Caenorhabditis elegans) |
Secernentea |
Y48B6A.13b3 |
-- |
40(a)
(best of 2) |
|
II(14220908-14226145) -- |
baker's yeast
(Saccharomyces cerevisiae) |
Saccharomycetes |
MVD1(YNR043W)4
MVD11 |
Mevalonate pyrophosphate decarboxylase, essential enzyme more4
Mvd1p1 |
48.99(n)1
48.82(a)1 |
|
14(701895-703085)4
8557791, 4 NP_014441.11, 4 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
AT3G542501 |
diphosphomevalonate decarboxylase |
52.79(n)
53.05(a) |
|
824592 NM_115285.2 NP_566995.1 |
rice
(Oryza sativa) |
Liliopsida |
Os.105432 |
Transcribed sequence with moderate similarity to protein more |
75.21(n) |
|
CB622472.1 |
ENSEMBL Gene Tree for MVD (if available)
TreeFam Gene Tree for MVD (if available) |
Paralogs
for MVD gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for MVD gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 16 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for MVD (88718343 - 88729569 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for MVD
2 CNVs: 4973 30011 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MVD |
|
Disorders
/ Diseases
for MVD gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
MVD for disorders About GeneDecksing
OMIM gene information: 603236
OMIM disorders: --
8  diseases for MVD: About MalaCards3-methylglutaconic aciduria cholesterol adrenoleukodystrophy pancreatic carcinoma
pancreatitis glioblastoma pneumonia carcinoma
Human Genome Epidemiology (HuGE) Navigator: MVD (19 documents)
Export disorders for MVD gene to outside databases
|
Publications
for MVD gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for MVD gene, integrated from 9 sources (see all 34):
(articles sorted by number of sources associating them with MVD) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Molecular cloning and expression of the cDNAs encoding human and yeast mevalonate pyrophosphate decarboxylase. (PubMed id 8626466)1, 2, 3, 9 Toth M.J. and Huwyler L. (1996)
- Human mevalonate diphosphate decarboxylase: characterization, investigation of the mevalonate diphosphate binding site, and crystal structure. (PubMed id 18823933)1, 2 Voynova N.E....Miziorko H.M. (2008)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Human mevalonate pyrophosphate decarboxylase is localized in the cytosol. (PubMed id 14972328)1, 9 Hogenboom S....Waterham H.R. (2004)
- Cholesterol biosynthesis is not defective in peroxisome biogenesis defective fibroblasts. (PubMed id 14680974)1, 9 Hogenboom S....Waterham H.R. (2003)
- Regulation of proliferation and Ras localization in transformed cells by products of mevalonate metabolism. (PubMed id 9270019)1, 9 Cuthbert J.A. and Lipsky P.E. (1997)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
|
External Searches for MVD gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing MVD gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing MVD gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing MVD gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for MVD | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for MVD gene:
Search GeneIP for patents involving MVD
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for MVD gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for MVD | | OriGene shRNA RFP for MVD | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MVD | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MVD | | | OriGene Protein Over-expression Lysate for MVD | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for MVD | | OriGene 3'-UTR Clone for MVD | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MVD | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MVD | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for MVD | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for MVD | | OriGene Custom Protein Services for MVD | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MVD | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MVD | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MVD | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MVD | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MVD | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MVD |
| |
 |  |  |  | |
| | | | Search Tocris compounds for MVD |
| |  |  |  |  | | | | | | Recombinant Protein for MVD |
|
 |
 |
 |
 | | | MVD Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MVD |
|  |  |  | | | | ThermoFisher Antibody for MVD |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MVD |
|
|
|
|
