Aliases for MUT Gene
External Ids for MUT Gene
This gene encodes the mitochondrial enzyme methylmalonyl Coenzyme A mutase. In humans, the product of this gene is a vitamin B12-dependent enzyme which catalyzes the isomerization of methylmalonyl-CoA to succinyl-CoA, while in other species this enzyme may have different functions. Mutations in this gene may lead to various types of methylmalonic aciduria. [provided by RefSeq, Jul 2008]
GeneCards Summary for MUT Gene
MUT (Methylmalonyl CoA Mutase) is a Protein Coding gene. Diseases associated with MUT include methylmalonyl-coenzyme a mutase deficiency and methylmalonic aciduria, mut(0) type. Among its related pathways are Disease and Metabolism. GO annotations related to this gene include cobalamin binding and methylmalonyl-CoA mutase activity.
UniProtKB/Swiss-Prot for MUT Gene
Involved in the degradation of several amino acids, odd-chain fatty acids and cholesterol via propionyl-CoA to the tricarboxylic acid cycle. MCM has different functions in other species