Aliases for MUT Gene
External Ids for MUT Gene
Previous GeneCards Identifiers for MUT Gene
This gene encodes the mitochondrial enzyme methylmalonyl Coenzyme A mutase. In humans, the product of this gene is a vitamin B12-dependent enzyme which catalyzes the isomerization of methylmalonyl-CoA to succinyl-CoA, while in other species this enzyme may have different functions. Mutations in this gene may lead to various types of methylmalonic aciduria. [provided by RefSeq, Jul 2008]
GeneCards Summary for MUT Gene
MUT (Methylmalonyl-CoA Mutase) is a Protein Coding gene. Diseases associated with MUT include Methylmalonic Aciduria, Mut(0) Type and Methylmalonic Aciduria, Vitamin B12-Responsive. Among its related pathways are Metabolism and Defective MMAA causes methylmalonic aciduria type cblA. GO annotations related to this gene include isomerase activity and modified amino acid binding.
UniProtKB/Swiss-Prot for MUT Gene
Involved in the degradation of several amino acids, odd-chain fatty acids and cholesterol via propionyl-CoA to the tricarboxylic acid cycle. MCM has different functions in other species.