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Aliases for MUSTN1 Gene

Aliases for MUSTN1 Gene

  • Musculoskeletal, Embryonic Nuclear Protein 1 2 3 5
  • Musculoskeletal Temporally Activated Novel 3
  • MUSTANG 3

External Ids for MUSTN1 Gene

Previous GeneCards Identifiers for MUSTN1 Gene

  • GC03M052825
  • GC03M052842
  • GC03M052847
  • GC03M052877

Summaries for MUSTN1 Gene

GeneCards Summary for MUSTN1 Gene

MUSTN1 (Musculoskeletal, Embryonic Nuclear Protein 1) is a Protein Coding gene.

UniProtKB/Swiss-Prot for MUSTN1 Gene

  • May be involved in the development and regeneration of the musculoskeletal system.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MUSTN1 Gene

Genomics for MUSTN1 Gene

Genomic Location for MUSTN1 Gene

Chromosome:
3
Start:
52,833,114 bp from pter
End:
52,835,219 bp from pter
Size:
2,106 bases
Orientation:
Minus strand

Genomic View for MUSTN1 Gene

Genes around MUSTN1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MUSTN1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MUSTN1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MUSTN1 Gene

Proteins for MUSTN1 Gene

  • Protein details for MUSTN1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8IVN3-MSTN1_HUMAN
    Recommended name:
    Musculoskeletal embryonic nuclear protein 1
    Protein Accession:
    Q8IVN3

    Protein attributes for MUSTN1 Gene

    Size:
    82 amino acids
    Molecular mass:
    8911 Da
    Quaternary structure:
    No Data Available

neXtProt entry for MUSTN1 Gene

Proteomics data for MUSTN1 Gene at MOPED

Post-translational modifications for MUSTN1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for MUSTN1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for MUSTN1 Gene

Domains & Families for MUSTN1 Gene

Protein Domains for MUSTN1 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for MUSTN1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8IVN3

UniProtKB/Swiss-Prot:

MSTN1_HUMAN :
  • Belongs to the MUSTANG family.
Family:
  • Belongs to the MUSTANG family.
genes like me logo Genes that share domains with MUSTN1: view

No data available for Gene Families for MUSTN1 Gene

Function for MUSTN1 Gene

Molecular function for MUSTN1 Gene

UniProtKB/Swiss-Prot Function:
May be involved in the development and regeneration of the musculoskeletal system.

Phenotypes for MUSTN1 Gene

GenomeRNAi human phenotypes for MUSTN1:
genes like me logo Genes that share phenotypes with MUSTN1: view

Animal Model Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MUSTN1 Gene

Localization for MUSTN1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for MUSTN1 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for MUSTN1 Gene COMPARTMENTS Subcellular localization image for MUSTN1 gene
Compartment Confidence
nucleus 3

No data available for Gene Ontology (GO) - Cellular Components for MUSTN1 Gene

Pathways & Interactions for MUSTN1 Gene

SuperPathways for MUSTN1 Gene

No Data Available

Interacting Proteins for MUSTN1 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000410910%0d%0a9606.ENSP00000263925%0d%0a
Selected Interacting proteins: ENSP00000410910 for MUSTN1 Gene via STRING

Symbol External ID(s) Details
LNX1

Gene Ontology (GO) - Biological Process for MUSTN1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0002062 chondrocyte differentiation IEA --
GO:0035988 chondrocyte proliferation IEA --
genes like me logo Genes that share ontologies with MUSTN1: view

No data available for Pathways by source and SIGNOR curated interactions for MUSTN1 Gene

Drugs & Compounds for MUSTN1 Gene

No Compound Related Data Available

Transcripts for MUSTN1 Gene

mRNA/cDNA for MUSTN1 Gene

Unigene Clusters for MUSTN1 Gene

Musculoskeletal, embryonic nuclear protein 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for MUSTN1 Gene

No ASD Table

Relevant External Links for MUSTN1 Gene

GeneLoc Exon Structure for
MUSTN1
ECgene alternative splicing isoforms for
MUSTN1

Expression for MUSTN1 Gene

mRNA expression in normal human tissues for MUSTN1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for MUSTN1 Gene

This gene is overexpressed in Muscle - Skeletal (x25.1), Artery - Tibial (x6.0), and Artery - Coronary (x4.8).

Protein differential expression in normal tissues from HIPED for MUSTN1 Gene

This gene is overexpressed in Heart (34.5), Stomach (13.9), and Tonsil (7.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for MUSTN1 Gene



SOURCE GeneReport for Unigene cluster for MUSTN1 Gene Hs.556077

genes like me logo Genes that share expression patterns with MUSTN1: view

Primer Products

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MUSTN1 Gene

Orthologs for MUSTN1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MUSTN1 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia MUSTN1 35
  • 91.46 (n)
  • 95.12 (a)
MUSTN1 36
  • 94 (a)
OneToMany
dog
(Canis familiaris)
Mammalia MUSTN1 35
  • 88.21 (n)
  • 89.02 (a)
-- 36
  • 82 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Mustn1 35
  • 85.37 (n)
  • 85.37 (a)
Mustn1 16
Mustn1 36
  • 84 (a)
OneToMany
chimpanzee
(Pan troglodytes)
Mammalia MUSTN1 35
  • 99.19 (n)
  • 97.56 (a)
rat
(Rattus norvegicus)
Mammalia Mustn1 35
  • 85.37 (n)
  • 86.59 (a)
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 87 (a)
OneToMany
chicken
(Gallus gallus)
Aves MUSTN1 35
  • 74.03 (n)
  • 80.52 (a)
MUSTN1 36
  • 78 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 77 (a)
OneToMany
tropical clawed frog
(Silurana tropicalis)
Amphibia mustn1 35
  • 68.33 (n)
  • 70 (a)
zebrafish
(Danio rerio)
Actinopterygii MUSTN1 36
  • 59 (a)
ManyToMany
mustn1a 36
  • 59 (a)
ManyToMany
Species with no ortholog for MUSTN1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MUSTN1 Gene

ENSEMBL:
Gene Tree for MUSTN1 (if available)
TreeFam:
Gene Tree for MUSTN1 (if available)

Paralogs for MUSTN1 Gene

(1) SIMAP similar genes for MUSTN1 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with MUSTN1: view

No data available for Paralogs for MUSTN1 Gene

Variants for MUSTN1 Gene

Structural Variations from Database of Genomic Variants (DGV) for MUSTN1 Gene

Variant ID Type Subtype PubMed ID
nsv834698 CNV Gain 17160897
nsv508928 CNV Insertion 20534489
nsv876797 CNV Loss 21882294

Variation tolerance for MUSTN1 Gene

Residual Variation Intolerance Score: 78.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.94; 19.54% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for MUSTN1 Gene

HapMap Linkage Disequilibrium report
MUSTN1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for MUSTN1 Gene

Disorders for MUSTN1 Gene

Relevant External Links for MUSTN1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MUSTN1

No disorders were found for MUSTN1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MUSTN1 Gene

Publications for MUSTN1 Gene

  1. Biological insights from 108 schizophrenia-associated genetic loci. (PMID: 25056061) (Nature 2014) 3 67
  2. Genome-wide association analyses identify 18 new loci associated with serum urate concentrations. (PMID: 23263486) KAPttgen A. … Gieger C. (Nat. Genet. 2013) 3
  3. Genome-wide association analysis identifies 13 new risk loci for schizophrenia. (PMID: 23974872) Ripke S. … Sullivan P.F. (Nat. Genet. 2013) 3
  4. Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4. (PMID: 21926972) (Nat. Genet. 2011) 3
  5. Biochemical and computational analysis of LNX1 interacting proteins. (PMID: 22087225) Wolting C.D. … McGlade C.J. (PLoS ONE 2011) 3

Products for MUSTN1 Gene

Sources for MUSTN1 Gene

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