Aliases for MUS81 Gene
External Ids for MUS81 Gene
GeneCards Summary for MUS81 Gene
MUS81 (MUS81 Structure-Specific Endonuclease Subunit) is a Protein Coding gene. Among its related pathways are Homologous recombination and Fanconi anemia pathway (KEGG). GO annotations related to this gene include 3-flap endonuclease activity.
UniProtKB/Swiss-Prot for MUS81 Gene
Interacts with EME1 and EME2 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5-end at the branch nick. Typical substrates include 3-flap structures, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication forks.