MUS81 Gene
protein-coding GIFtS: 62
GCID: GC11P065627
|
|
MUS81 endonuclease homolog (S. cerevisiae)(Previous name: MUS81 endonuclease homolog (yeast) )
| |
Aliases
for MUS81 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| MUS81 Endonuclease Homolog (S. Cerevisiae)1 2 | | Crossover Junction Endonuclease MUS812 | | SLX31 2 | | SLX3 Structure-Specific Endonuclease Subunit Homolog2 | | FLJ448721 | | EC 3.1.22.-3 | | MUS81 Endonuclease Homolog (Yeast)1 | | EC 3.1.228 |
Export aliases for MUS81 gene to outside databasesPrevious GC identifers: GC11P068162 GC11P067309 GC11P065878 GC11P065403 GC11P065384 GC11P061954 |
Summaries
for MUS81 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: MUS81_HUMAN, Q96NY9Function: Interacts with EME1 and EME2 to form a DNA structure-specific endonuclease with substrate preference forbranched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replicationforks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replicationforks
Gene Wiki entry for MUS81
|
Genomic Views
for MUS81 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000011.9 NC_018922.1 NT_167190.1
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the MUS81 gene promoter:
AP-1 Pax-6 COMP1 Pax-2 Lmo2 AP-4 AP-2gamma E47 GATA-2
Other transcription factors
Search SABiosciences Chromatin IP Primers for MUS81
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MUS81 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 11q13 Ensembl cytogenetic band: 11q13.1 HGNC cytogenetic band: 11q13MUS81 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 11 GeneLoc Exon Structure GeneLoc location for GC11P065627: view genomic region
(about GC identifiers)
Start:
|
65,624,597 bp from pter |
End:
|
65,635,124 bp from pter |
Size:
|
10,528 bases |
Orientation:
|
plus strand |
|
Proteins
for MUS81 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: MUS81_HUMAN, Q96NY9 (See
protein sequence)Recommended Name: Crossover junction endonuclease MUS81 Size: 551 amino acids; 61173 Da
Cofactor: Magnesium
Subunit: May self-associate. Interacts with EME1, EME2 and CHEK2. Interacts with BLM, and this interaction maystimulate the endonuclease activity of MUS81. Interacts with SLX4/BTBD12; this interaction is direct and links theMUS81-EME1 complex to SLX4, which may coordinate the action of the structure-specific endonuclease during DNA repair.Interacts with DCLRE1B/Apollo
Subcellular location: Nucleus, nucleolus. Note=Recruited to foci of DNA damage in S-phase cells
Developmental stage: Expressed in S phase and G2 phase
Sequence caution: Sequence=BAB14953.1; Type=Erroneous initiation;
1 PDB 3D structure from  and Proteopedia  for MUS81:2ZIX (3D)
Secondary accessions: Q9H7D9Explore the universe of human proteins at neXtProt for MUS81: NX_Q96NY9
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q96NY9
4/7 DME Specific Peptides for MUS81 (Q96NY9) (see all 7)
MUS81 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_079404.3
ENSEMBL proteins: ENSP00000431979 ENSP00000432287 ENSP00000307853 ENSP00000431478 ENSP00000433473 ENSP00000434305 ENSP00000433809 ENSP00000435277 ENSP00000387722
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005730 | nucleolus |
IEA | -- |
MUS81 for ontologies About GeneDecksing
MUS81 Antibody Products:
Assay Products for MUS81: |
Protein
Domains /
Families
for MUS81 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
MUS81 for domains About GeneDecksing
5 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q96NY9ProtoNet protein and cluster: Q96NY9 1 Blocks protein family: IPB003583 Helix-hairpin-helix DNA-binding
UniProtKB/Swiss-Prot: MUS81_HUMAN, Q96NY9Similarity: Belongs to the XPF familySimilarity: Contains 1 ERCC4 domain |
Function
for MUS81 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: MUS81_HUMAN, Q96NY9Function: Interacts with EME1 and EME2 to form a DNA structure-specific endonuclease with substrate preference forbranched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replicationforks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replicationforksInduction: Up-regulated in cells treated with agents that damage DNA or block replication. This up-regulation seems tobe independent of transcriptionEnzyme Numbers (IUBMB): EC 3.1.222 EC 3.1.22.-1
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MUS81 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MUS81
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: MUS81 (NM_025128) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MUS81 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MUS81 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MUS81 |
Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6): About this table
MUS81 for ontologies About GeneDecksing
Animal Models:
Mouse knock-outs for MUS81: Mus81tm1Raz Mus81tm1Chmg Mus81tm1Esse
7 MGI mutant phenotypes (inferred from 3 alleles ) (MGI details for Mus81):
MUS81 for phenotypes About GeneDecksing
|
Pathways & Interactions
for MUS81 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Homologous recombination | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 
Kegg Pathway (Kegg details for MUS81):
MUS81 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for MUS81
STRING Interaction
Network Preview (showing 5 interactants - click image to see 22)
5/93 Interacting proteins for MUS81 (Q96NY91, 2, 3 ENSP000003078534) via UniProtKB, MINT, STRING, and/or I2D (see all 93)About this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table
MUS81 for ontologies About GeneDecksing
|
Drugs & Compounds
for MUS81 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for MUS81
1 HMDB Compound for MUS81 About this table
Search CenterWatch for drugs/clinical trials and news about MUS81
|
Transcripts
for MUS81 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for MUS81 gene: NM_025128.4 Unigene Cluster for MUS81: MUS81 endonuclease homolog (S. cerevisiae) Hs.288798 [show with all ESTs]Unigene Representative Sequence: NM_02512818 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000529857 ENST00000533035 ENST00000308110(uc001ofv.4) ENST00000525768
ENST00000524647 ENST00000529374 ENST00000533555 ENST00000531905(uc001ofx.4)
ENST00000530111 ENST00000530928 ENST00000525147 ENST00000525224 ENST00000529786
ENST00000530282 ENST00000533519 ENST00000529742 ENST00000525006 ENST00000437855
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MUS81 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MUS81
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: MUS81 (NM_025128) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MUS81 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MUS81 |
Additional cDNA sequence: AF425646.1 AK024665.1 AK126820.1 AK223564.1 BC009999.2 23 DOTS entries: DT.100753361 DT.446431 DT.97843902 DT.100789120 DT.92469985 DT.75102765 DT.100760063 DT.95226196 DT.101984329 DT.120690202 DT.453509 DT.120690336 DT.100789119 DT.95226192 DT.120690144 DT.120690230 DT.100710960 DT.100789113 DT.100829169 DT.120690083 DT.95194773 DT.95226197 DT.120690081 24/183 AceView cDNA sequences (see all 183): BU626130 BQ007168 AI004770 AI423724 AA989261 AW057824 AW081005 AI708157 AI696162 BM715429 CA428478 BF594519 W46505 AW008546 AI174987 AL353934 BM787599 CR604400 AA361844 BP349348 AI444946 BX376440 AA310067 AW954207
GeneLoc Exon Structure
5/10 Alternative Splicing Database (ASD) splice patterns (SP) for MUS81 (see all 10) About this scheme
| ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3a | · | 3b | ^ | 4a | · | 4b | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9a | · | 9b | ^ | 10a | · | 10b | · | 10c | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14a | · | 14b | · | 14c | ^ | 15a | · | 15b | ^ | 16a | · |
|---|
|
| SP1: | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | - | | - | | - | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | - | | - | | - | | | | | | | | |
| SP4: | | | - | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 16b | · | 16c | ^ | 17 | ^ | 18a | · | 18b | · | 18c | · | 18d |
|---|
|
| SP1: | | | - | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for MUS81
|
Expression
for MUS81 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| MUS81 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TAGAAGATGC
About this image
See MUS81 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for MUS81
SOURCE GeneReport for Unigene cluster: Hs.288798
UniProtKB/Swiss-Prot: MUS81_HUMAN, Q96NY9Tissue specificity: Widely expressed
SABiosciences Expression via Pathway-Focused PCR Arrays including MUS81:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MUS81
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat MUS81 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MUS81 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MUS81 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MUS81 |
Orthologs
for MUS81 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for MUS81 gene from 8/27 species (see all 27) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Mus811 , 5 |
MUS81 endonuclease homolog (yeast)1, 5 |
82.79(n)1
82(a)1 |
|
19 (4.34 cM)5
717111 NM_027877.31 NP_082153.31
54823455 |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.55722 |
Xenopus laevis transcribed sequence with weak similarity more |
76.04(n) |
|
BJ037176.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
wufc26g012 |
Danio rerio cDNA clone MGC66489 IMAGE2601539, complete more |
76.08(n) |
|
BC055679.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
mus811 , 3 |
CG3026-PA1 |
42(a)3
51.2(n)1
45(a)1 |
|
1D23
310441 NM_130517.21 NP_569873.11 |
worm
(Caenorhabditis elegans) |
Secernentea |
mus-816 |
MUS (Drosophila mutagen sensitive) related family ... |
22(a) |
1 ↔ 1 |
I(4265108-4267187) |
baker's yeast
(Saccharomyces cerevisiae) |
Saccharomycetes |
MUS81(YDR386W)4
MUS811 |
Subunit of the structure-specific Mms4p-Mus81p endonuclease more4
Mus81p1 |
38.44(n)1
31.05(a)1 |
|
4(1246084-1247982)4
8519941, 4 NP_010674.31 NP_010674.14 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
AT5G397706ATMUS816 |
crossover junction endonuclease MUS81 |
9(a)17(a) |
many → 1many → 1 |
5(15919241-15927549) 4(15028427-15032634) |
rice
(Oryza sativa) |
Liliopsida |
-- |
endonuclease, putative, expressed |
18(a) |
1 ↔ 1 |
1(41690131-41697663) |
ENSEMBL Gene Tree for MUS81 (if available)
TreeFam Gene Tree for MUS81 (if available) |
Paralogs
for MUS81 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for MUS81 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 11 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for MUS81 (65624597 - 65635124 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for MUS81
1 CNV: 3855 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MUS81 |
|
Disorders
/ Diseases
for MUS81 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
MUS81 for disorders About GeneDecksing
OMIM gene information: 606591
OMIM disorders: --
11  diseases for MUS81: About MalaCardslaryngeal squamous cell carcinoma squamous cell carcinoma bloom syndrome fanconi's anemia
laryngitis multiple sclerosis anemia osteoarthritis
gastric cancer breast cancer carcinoma
2 diseases from the University of Copenhagen DISEASES database for MUS81:Bloom syndrome Fanconi's anemia Human Genome Epidemiology (HuGE) Navigator: MUS81 (7 documents)
Export disorders for MUS81 gene to outside databases
|
Publications
for MUS81 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for MUS81 gene, integrated from 9 sources (see all 50):
(articles sorted by number of sources associating them with MUS81) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Human Mus81-associated endonuclease cleaves Holliday junctions in vitro. (PubMed id 11741546)1, 2, 3, 9 Chen X.-B.... McGowan C.H. (2001)
- Holliday junction resolution in human cells: two junction endonucleases with distinct substrate specificities. (PubMed id 12374758)1, 2, 3, 9 Constantinou A....West S.C. (2002)
- Mus81 endonuclease localizes to nucleoli and to regions of DNA damage in human S-phase cells. (PubMed id 14638871)1, 2, 9 Gao H.... McGowan C.H. (2003)
- RNA interference inhibition of Mus81 reduces mitotic recombination in human cells. (PubMed id 14617801)1, 2, 9 Blais V.... McGowan C.H. (2004)
- BLM helicase facilitates Mus81 endonuclease activity in human cells. (PubMed id 15805243)1, 2, 9 Zhang R.... Harris C.C. (2005)
- Coordination of structure-specific nucleases by human SLX4/BTBD12 is required for DNA repair. (PubMed id 19595721)1, 2, 9 Munoz I.M.... Rouse J. (2009)
- Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair. (PubMed id 19596235)1, 2 Svendsen J.M.... Harper J.W. (2009)
- Human SLX4 is a Holliday junction resolvase subunit that binds multiple DNA repair/recombination endonucleases. (PubMed id 19596236)1, 2 Fekairi S.... Gaillard P.-H.L. (2009)
- Identification of FAAP24, a Fanconi anemia core complex protein that interacts with FANCM. (PubMed id 17289582)1, 2 Ciccia A....West S.C. (2007)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
|
External Searches for MUS81 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing MUS81 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing MUS81 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing MUS81 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for MUS81 gene:
Search GeneIP for patents involving MUS81
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for MUS81 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
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| | |  | OriGene Antibodies for MUS81 | | Browse OriGene shRNA RFPs | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MUS81 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MUS81 | | | OriGene Protein Over-expression Lysate for MUS81 | | Browse OriGene Fluorogenic Cell Assay Kits | | | Browse OriGene siRNAs | | OriGene 3'-UTR Clone for MUS81 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MUS81 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MUS81 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for MUS81 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for MUS81 | | OriGene Custom Protein Services for MUS81 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MUS81 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MUS81 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MUS81 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MUS81 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MUS81 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MUS81 |
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| | | | Search Tocris compounds for MUS81 |
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 | | | MUS81 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MUS81 |
|  |  |  | | | | ThermoFisher Antibodies for MUS81 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MUS81 |
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