Aliases for MURC Gene
External Ids for MURC Gene
Previous GeneCards Identifiers for MURC Gene
This gene encodes a protein containing two coiled-coil regions. The encoded protein promotes Rho/ROCK (Rho-kinase) signaling in cardiac muscles cells, and may facilitate myofibrillar organization. [provided by RefSeq, Jun 2013]
GeneCards Summary for MURC Gene
MURC (Muscle Related Coiled-Coil Protein) is a Protein Coding gene. Diseases associated with MURC include testicular anomalies with or without congenital heart disease and bejel. An important paralog of this gene is PTRF.
UniProtKB/Swiss-Prot for MURC Gene
Induces RHOA activation and activates NPPA transcription and myofibrillar organization through the Rho/ROCK signaling pathway.