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Aliases for MUM1L1 Gene

Aliases for MUM1L1 Gene

  • Melanoma Associated Antigen (Mutated) 1-Like 1 2 3
  • Mutated Melanoma-Associated Antigen 1-Like Protein 1 4
  • MUM1-Like Protein 1 4

External Ids for MUM1L1 Gene

Previous GeneCards Identifiers for MUM1L1 Gene

  • GC0XP105218
  • GC0XP105412
  • GC0XP095038

Summaries for MUM1L1 Gene

Entrez Gene Summary for MUM1L1 Gene

  • This gene encodes a protein which contains a mutated melanoma-associated antigen 1 domain. Proteins which contain mutated antigens are expressed at high levels on certain types of cancers. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2011]

GeneCards Summary for MUM1L1 Gene

MUM1L1 (Melanoma Associated Antigen (Mutated) 1-Like 1) is a Protein Coding gene. Diseases associated with MUM1L1 include melanoma.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MUM1L1 Gene

Genomics for MUM1L1 Gene

Regulatory Elements for MUM1L1 Gene

Genomic Location for MUM1L1 Gene

106,168,305 bp from pter
106,208,956 bp from pter
40,652 bases
Plus strand

Genomic View for MUM1L1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MUM1L1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MUM1L1 Gene

Proteins for MUM1L1 Gene

  • Protein details for MUM1L1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    PWWP domain-containing protein MUM1L1
    Protein Accession:
    Secondary Accessions:
    • D3DUX2
    • Q49AS5
    • Q8N2C0
    • Q96MT6

    Protein attributes for MUM1L1 Gene

    696 amino acids
    Molecular mass:
    79040 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAH31229.1; Type=Frameshift; Positions=406; Evidence={ECO:0000305}; Sequence=BAB71194.1; Type=Erroneous termination; Positions=638; Note=Translated as Glu.; Evidence={ECO:0000305};

neXtProt entry for MUM1L1 Gene

Proteomics data for MUM1L1 Gene at MOPED

Post-translational modifications for MUM1L1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for MUM1L1 Gene

No data available for DME Specific Peptides for MUM1L1 Gene

Domains for MUM1L1 Gene

Protein Domains for MUM1L1 Gene


Suggested Antigen Peptide Sequences for MUM1L1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Q5H9M0
  • Contains 1 PWWP domain.
  • Belongs to the MUM1 family.
genes like me logo Genes that share domains with MUM1L1: view

No data available for Gene Families for MUM1L1 Gene

Function for MUM1L1 Gene

Animal Model Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for MUM1L1

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MUM1L1 Gene

Localization for MUM1L1 Gene

Subcellular locations from

Jensen Localization Image for MUM1L1 Gene COMPARTMENTS Subcellular localization image for MUM1L1 gene
Compartment Confidence
nucleus 2
cytosol 1
extracellular 1
mitochondrion 1
peroxisome 1
plasma membrane 1

Gene Ontology (GO) - Cellular Components for MUM1L1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0070062 extracellular exosome IDA 19056867
genes like me logo Genes that share ontologies with MUM1L1: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for MUM1L1 Gene

Pathways for MUM1L1 Gene

SuperPathways for MUM1L1 Gene

No Data Available

Interacting Proteins for MUM1L1 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: ENSP00000338641 for MUM1L1 Gene via STRING

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for MUM1L1 Gene


No data available for Pathways by source for MUM1L1 Gene

Transcripts for MUM1L1 Gene

Unigene Clusters for MUM1L1 Gene

Melanoma associated antigen (mutated) 1-like 1:
Representative Sequences:

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for MUM1L1

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MUM1L1 Gene

No ASD Table

Relevant External Links for MUM1L1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MUM1L1 Gene

mRNA expression in normal human tissues for MUM1L1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for MUM1L1 Gene

This gene is overexpressed in Ovary (20.0).

Protein differential expression in normal tissues for MUM1L1 Gene

This gene is overexpressed in Ovary (54.4), Platelet (8.3), and Testis (6.3).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for MUM1L1 Gene

SOURCE GeneReport for Unigene cluster for MUM1L1 Gene Hs.592221

genes like me logo Genes that share expressions with MUM1L1: view

Expression partners for MUM1L1 Gene

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for MUM1L1 Gene

Orthologs for MUM1L1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MUM1L1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia MUM1L1 35
  • 84.49 (n)
  • 77.46 (a)
MUM1L1 36
  • 77 (a)
(Canis familiaris)
Mammalia MUM1L1 35
  • 85.14 (n)
  • 77.71 (a)
MUM1L1 36
  • 77 (a)
(Mus musculus)
Mammalia Mum1l1 35
  • 75.36 (n)
  • 67.56 (a)
Mum1l1 16
Mum1l1 36
  • 67 (a)
(Pan troglodytes)
Mammalia MUM1L1 35
  • 99.38 (n)
  • 98.56 (a)
MUM1L1 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Mum1l1 35
  • 76.16 (n)
  • 68.1 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 34 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 34 (a)
(Gallus gallus)
Aves -- 36
  • 29 (a)
(Danio rerio)
Actinopterygii MUM1L1 36
  • 16 (a)
Species with no ortholog for MUM1L1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MUM1L1 Gene

Gene Tree for MUM1L1 (if available)
Gene Tree for MUM1L1 (if available)

Paralogs for MUM1L1 Gene

Selected SIMAP similar genes for MUM1L1 Gene using alignment to 1 proteins: Pseudogenes for MUM1L1 Gene

genes like me logo Genes that share paralogs with MUM1L1: view

No data available for Paralogs for MUM1L1 Gene

Variants for MUM1L1 Gene

Sequence variations from dbSNP and Humsavar for MUM1L1 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs911855 -- 106,170,646(+) CCATT(C/G)AAAAT intron-variant
rs1757443 -- 106,167,525(+) GAAGT(A/G)AATAT upstream-variant-2KB
rs2027827 -- 106,209,109(+) AACAC(C/T)TGCTA downstream-variant-500B
rs2071696 -- 106,201,396(+) CCTAT(A/G)GGGTT intron-variant, upstream-variant-2KB
rs2187698 -- 106,185,030(+) gcata(A/G)ttgtg intron-variant

Structural Variations from Database of Genomic Variants (DGV) for MUM1L1 Gene

Variant ID Type Subtype PubMed ID
esv2752312 CNV Gain 17911159
nsv521259 CNV Gain 19592680

Relevant External Links for MUM1L1 Gene

HapMap Linkage Disequilibrium report
Locus Specific Mutation Databases (LSDB)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MUM1L1 Gene

Disorders for MUM1L1 Gene

MalaCards: The human disease database

MalaCards: The human disease database.

Search for MUM1L1 Gene in MalaCards »

(1) Diseases for MUM1L1 Gene including...

genes like me logo Genes that share disorders with MUM1L1: view

No data available for OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for MUM1L1 Gene

Publications for MUM1L1 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 3 4
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  4. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PMID: 15146197) Brandenberger R. … Stanton L.W. (Nat. Biotechnol. 2004) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for MUM1L1 Gene

Sources for MUM1L1 Gene

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