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MUM1 Gene

protein-coding   GIFtS: 51
GCID: GC19P001285

Melanoma Associated Antigen (Mutated) 1

  See MUM1-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Melanoma Associated Antigen (Mutated) 11 2     MUM-12 3
Mutated Melanoma-Associated Antigen 12 3     HSPC2112
Protein Expandere2 3     Melanoma Ubiquitous Mutated Protein2
EXPAND12 3     PWWP Domain-Containing Protein MUM12

External Ids:    HGNC: 296411   Entrez Gene: 849392   Ensembl: ENSG000001609537   UniProtKB: Q2TAK83   

Export aliases for MUM1 gene to outside databases

Previous GC identifers: GC00U914363 GC19P001307 GC19P001300 GC19P001129


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for MUM1 Gene:
MUM1 (melanoma associated antigen (mutated) 1) is a protein-coding gene. Diseases associated with MUM1 include nodular lymphocyte predominant hodgkin lymphoma, and primary mediastinal large b-cell lymphoma. GO annotations related to this gene include nucleosome binding. An important paralog of this gene is MUM1L1.

UniProtKB/Swiss-Prot: MUM1_HUMAN, Q2TAK8
Function: Involved in the DNA damage response pathway by contributing to the maintenance of chromatin
architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate
damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell
survival following DNA damage




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000019.9  NC_018930.2  NT_011295.12  
Regulatory elements:
   Regulatory transcription factor binding sites in the MUM1 gene promoter:
         SRF   TBP   p53   SRF (504 AA)   RSRFC4   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for MUM1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MUM1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19p13.3   Ensembl cytogenetic band:  19p13.3   HGNC cytogenetic band: 19p13.3

MUM1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MUM1 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19P001285:  view genomic region     (about GC identifiers)

Start:
1,285,890 bp from pter      End:
1,378,430 bp from pter
Size:
92,541 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: MUM1_HUMAN, Q2TAK8 (See protein sequence)
Recommended Name: PWWP domain-containing protein MUM1  
Size: 710 amino acids; 78636 Da
Subunit: Interacts with TP53BP1 (via BRCT domain); the interaction is not dependent on its phosphorylation status.
Binds nucleosomes. Interacts with trimethylated 'Lys-36' of histone H3 (H3K36me3) (in vitro)
Miscellaneous: Acts as an antigenic peptide recognized by cytolytic T-lymphocytes in a melanoma (PubMed:7644523)
Sequence caution: Sequence=AAC50240.1; Type=Frameshift; Positions=4; Sequence=AAH08098.1; Type=Erroneous
initiation; Note=Translation N-terminally extended; Sequence=AAI10875.1; Type=Erroneous initiation;
Note=Translation N-terminally shortened; Sequence=BAB55357.1; Type=Erroneous initiation; Note=Translation
N-terminally extended; Sequence=BAC11493.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
1 PDB 3D structure from and Proteopedia for MUM1:
3PMI (3D)    
Secondary accessions: A1L489 B5ME02 Q13109 Q5XKB9 Q8N2I4 Q96A67
Alternative splicing: 2 isoforms:  Q2TAK8-1   Q2TAK8-2   

Explore the universe of human proteins at neXtProt for MUM1: NX_Q2TAK8

Explore proteomics data for MUM1 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys642
  • Modification sites at PhosphoSitePlus

  • See MUM1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_116242.2  
    ENSEMBL proteins: 
     ENSP00000466891   ENSP00000467287   ENSP00000468557   ENSP00000468322   ENSP00000467083  
     ENSP00000465838   ENSP00000394925   ENSP00000345789   ENSP00000309135  

    MUM1 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for MUM1

     
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    antibodies-online peptides for MUM1

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    antibodies-online antibodies for MUM1 (37 products) 

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    antibodies-online kits for MUM1 (7 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    ProtoNet protein and cluster: Q2TAK8

    UniProtKB/Swiss-Prot: MUM1_HUMAN, Q2TAK8
    Domain: The PWWP domain mediates the interaction with nucleosomes
    Similarity: Belongs to the MUM1 family
    Similarity: Contains 1 PWWP domain


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: MUM1_HUMAN, Q2TAK8
    Function: Involved in the DNA damage response pathway by contributing to the maintenance of chromatin
    architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate
    damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell
    survival following DNA damage

         Genatlas biochemistry entry for MUM1:
    multiple myeloma oncogene 1,same as IRF4,overexpressed in myeloma with translocation t(6;14)(p25;q32)

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
    GO:0031491nucleosome binding IDA--
         
    Find genes that share ontologies with MUM1           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for MUM1:
     Increased G1 DNA content 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for MUM1

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MUM1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    MUM1_HUMAN, Q2TAK8: Nucleus. Note=Recuited to DNA damage sites via its interaction with the BRCT domain of
    TP53BP1
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol2
    plasma membrane1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--

    Find genes that share ontologies with MUM1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for MUM1
    Interactions:

        Search GeneGlobe Interaction Network for MUM1

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    4 Interacting proteins for MUM1 (Q2TAK83 ENSP000003457894) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    DMAP1Q9NPF53I2D: score=1 
    HIST2H3CENSP000003581544STRING: ENSP00000358154
    TRAF2ENSP000002476684STRING: ENSP00000247668
    ELAVL1ENSP000003852694STRING: ENSP00000385269
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006281DNA repair IMP--
    GO:0006325chromatin organization IMP--

    Find genes that share ontologies with MUM1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for MUM1



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for MUM1 gene: 
    NM_032853.3  

    Unigene Cluster for MUM1:

    Melanoma associated antigen (mutated) 1
    Hs.515016  [show with all ESTs]
    Unigene Representative Sequence: NR_024247
    18 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000592374 ENST00000588351 ENST00000591337 ENST00000590866 ENST00000588810
    ENST00000591433 ENST00000591806 ENST00000587460 ENST00000415183(uc010dsi.2)
    ENST00000590695 ENST00000586996 ENST00000585399 ENST00000586067 ENST00000591627
    ENST00000591453 ENST00000588888 ENST00000344663(uc002lrz.2 uc010xgm.1 uc002lsd.2)
    ENST00000311401(uc002lsb.2 uc002lsc.1)
    miRNA
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    OriGene qPCR primer pairs and template standards for MUM1
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat MUM1
      QuantiTect SYBR Green Assays in human, mouse, rat MUM1
      QuantiFast Probe-based Assays in human, mouse, rat MUM1

    Additional mRNA sequence: 

    AF151045.1 AK025936.1 AK075241.1 AK309092.1 AL360266.1 BC001806.1 BC008098.1 BC019585.1 
    BC021016.1 BC082987.1 BC110874.1 BC130443.1 BC144138.1 BC144147.1 CR457395.1 NR_024247.1 
    U20896.1 U20897.1 

    23 DOTS entries:

    DT.121495026  DT.310602  DT.121495056  DT.121494893  DT.100749543  DT.97796015  DT.121495111  DT.40106483 
    DT.95378836  DT.97808070  DT.97811164  DT.86856171  DT.121494943  DT.92426166  DT.92426168  DT.95264281 
    DT.121494903  DT.121494925  DT.40192158  DT.91757739  DT.95078688  DT.121494979  DT.75178837 

    Selected AceView cDNA sequences (see all 225):

    BM477708 D44937 BM823773 BQ184135 BC008098 BE669475 AW205680 BU541563 
    AW082356 BQ939678 AA291374 BU623021 BM704888 AI289509 BM984070 BM697775 
    CR617170 AI554518 BF940515 BE502869 NM_032853 T09489 BQ640489 AW300750 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for MUM1 (see all 15)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b · 5c ^ 6a · 6b ^ 7a · 7b · 7c · 7d · 7e · 7f ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15a · 15b ^
    SP1:                                                                                                                                                            
    SP2:                                                                                                                                                            
    SP3:                                                                                                                                                            
    SP4:                                -     -     -                 -                                                                                             
    SP5:                                -     -     -           -     -                                                                                             

    ExUns: 16 ^ 17a · 17b ^ 18 ^ 19a · 19b · 19c
    SP1:                                          
    SP2:                                          
    SP3:  -     -           -                     
    SP4:                                          
    SP5:                                          


    ECgene alternative splicing isoforms for MUM1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    MUM1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GTTTTGTGGG
    MUM1 Expression
    About this image


    MUM1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Neural Tube (Nervous System)
             Mesencephalic Ventricular Zone
     
     Testis (Reproductive System)
    MUM1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    MUM1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.515016
        Custom PCR Arrays for MUM1
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MUM1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for MUM1 gene from Selected species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Mum11 , 5 melanoma associated antigen (mutated) 11, 5 67.97(n)1
    63.12(a)1
      10 (39.72 cM)5
    681141  NM_023431.51  NP_075920.41 
     802264345 
    chicken
    (Gallus gallus)
    Aves MUM11 melanoma associated antigen (mutated) 1 57.03(n)
    50.42(a)
      425514  XM_423267.4  XP_423267.4 
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.24072 Transcribed sequence with strong similarity to protein more 69.08(n)    AL957114.2 
    zebrafish
    (Danio rerio)
    Actinopterygii MUM1L16
    melanoma associated antigen (mutated) 1-like 1
    16(a)
    1 → many
    2(37170127-37182556) ENSDARG00000060395


    ENSEMBL Gene Tree for MUM1 (if available)
    TreeFam Gene Tree for MUM1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for MUM1 gene
    MUM1L12  
    2 SIMAP similar genes for MUM1 using alignment to 10 protein entries:     MUM1_HUMAN (see all proteins):
    MUM-1    MUM1L1

    Find genes that share paralogs with MUM1           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for MUM1 (see all 766)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs664773741,2
    C,F--1353104(+) AGGCGA/GTATGT 1 -- us2k18Minor allele frequency- G:0.34NA WA CSA EA 368
    rs1813920861,2
    C--1353171(+) TTTAAC/TGTGAG 1 -- us2k10--------
    rs1390686951,2
    --1353208(+) AACCAC/TCCACA 1 -- us2k10--------
    rs1855310351,2
    --1353347(+) CAGCAC/TAGCAA 1 -- us2k10--------
    rs1440610421,2
    --1353423(+) ACTCCA/GGAGGC 1 -- us2k10--------
    rs1147701051,2
    F--1353473(+) GCAGTG/AAGCTA 1 -- us2k11Minor allele frequency- A:0.05WA 118
    rs1906852681,2
    --1353536(+) AAATGC/TAAATA 1 -- us2k10--------
    rs1459739271,2
    --1353677(+) TAGAGC/TCGGCT 1 -- us2k10--------
    rs81133751,2
    A--1353878(+) aatagC/Ttggga 1 -- us2k10--------
    rs1829203781,2
    --1353893(+) AGGCAA/TCGCCA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for MUM1 (1285890 - 1378430 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for MUM1 (see all 28):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2717841CNV Deletion23290073
    esv2717842CNV Deletion23290073
    esv2717843CNV Deletion23290073
    esv1153316CNV Insertion17803354
    dgv3589n71CNV Loss21882294
    nsv910476CNV Loss21882294
    nsv910292CNV Loss21882294
    nsv910489CNV Loss21882294
    dgv3595n71CNV Loss21882294
    dgv3555n71CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing MUM1
    DNA2.0 Custom Variant and Variant Library Synthesis for MUM1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    3 diseases for MUM1:    
    About MalaCards
    nodular lymphocyte predominant hodgkin lymphoma    primary mediastinal large b-cell lymphoma    melanoma

    1 disease from the University of Copenhagen DISEASES database for MUM1:
    Diffuse large B-cell lymphoma

    Find genes that share disorders with MUM1           About GenesLikeMe


    Export disorders for MUM1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for MUM1 gene, integrated from 10 sources (see all 22):
    (articles sorted by number of sources associating them with MUM1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A mutated intron sequence codes for an antigenic peptide recognized by cytolytic T lymphocytes on a human melanoma. (PubMed id 7644523)1, 2, 3 Coulie P.G.... Boon T. (Proc. Natl. Acad. Sci. U.S.A. 1995)
    2. Structural and histone binding ability characterizations of human PWWP domains. (PubMed id 21720545)1, 2 Wu H.... Min J. (PLoS ONE 2011)
    3. Regulation of chromatin architecture by the PWWP domain-containing DNA damage-responsive factor EXPAND1/MUM1. (PubMed id 20347427)1, 2 Huen M.S.... Chen J. (Mol. Cell 2010)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)1, 3 Zhang Q.-H.... Chen Z. (Genome Res. 2000)
    6. Bcl2-associated athanogene 3 interactome analysis reveals a new role in modulating proteasome activity. (PubMed id 23824909)1 Chen Y....Ge F. (amp 2013)
    7. MUM-1 expression differentiates tumors in the PEComa family from clear cell sarcoma and melanoma. (PubMed id 21903680)1 Ferenczi K....Zhang P.J. (Int. J. Surg. Pathol. 2012)
    8. [Significance of MUM-1/IRF4 protein expression in follicular lymphoma]. (PubMed id 22169641)1 Huo Y.Y....Meng B. (Zhonghua Bing Li Xue Za Zhi 2011)
    9. Immunohistochemical expression of Mum-1, Oct-2 and Bcl-6 in systemic anaplastic large cell lymphomas. (PubMed id 22158496)1 Saglam A. and Uner A.H. (Tumori 2011)
    10. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 84939 HGNC: 29641 AceView: MUM1 Ensembl:ENSG00000160953 euGenes: HUgn84939
    ECgene: MUM1 H-InvDB: MUM1

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for MUM1 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for MUM1 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for MUM1 gene:
    Search GeneIP for patents involving MUM1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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