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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

MUM1 Gene

protein-coding GIFtS: 51
GCID: GC19P001285

melanoma associated antigen (mutated) 1

Explore 6 diseases affiliated with
MUM1 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Melanoma Associated Antigen (Mutated) 1¹ ²		EXPAND1² ³
MUM-1¹ ² ³		HSPC211²
Mutated Melanoma-Associated Antigen 1² ³		Melanoma Ubiquitous Mutated Protein²
Protein Expandere² ³		PWWP Domain-Containing Protein MUM1²

External Ids:	HGNC: 29641¹	Entrez Gene: 84939²	Ensembl: ENSG00000160953⁷	UniProtKB: Q2TAK8³

Export aliases for MUM1 gene to outside databases

Previous GC identifers: GC00U914363 GC19P001307 GC19P001300 GC19P001129

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: MUM1_HUMAN, Q2TAK8

Function: Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture.

Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin

changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000019.9 NC_018930.1 NT_011255.14

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the MUM1 gene promoter:
SRF TBP p53 SRF (504 AA) RSRFC4
Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids

Search SABiosciences Chromatin IP Primers for MUM1

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MUM1

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19p13.3 Ensembl cytogenetic band: 19p13.3 HGNC cytogenetic band: 19p13.3

MUM1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MUM1 gene location

GeneLoc information about chromosome 19 GeneLoc Exon Structure

GeneLoc location for GC19P001285: view genomic region (about GC identifiers)

Start:	1,285,890 bp from pter	End:	1,378,430 bp from pter
Size:	92,541 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: MUM1_HUMAN, Q2TAK8 (See protein sequence)

Recommended Name: PWWP domain-containing protein MUM1

Size: 710 amino acids; 78636 Da

Subunit: Interacts with TP53BP1 (via BRCT domain); the interaction is not dependent on its phosphorylation status.

Binds nucleosomes

Subcellular location: Nucleus. Note=Recuited to DNA damage sites via its interaction with the BRCT domain of TP53BP1

Miscellaneous: Acts as an antigenic peptide recognized by cytolytic T-lymphocytes in a melanoma (PubMed:7644523)

Sequence caution: Sequence=AAC50240.1; Type=Frameshift; Positions=4; Sequence=AAH08098.1; Type=Erroneous initiation;

Note=Translation N-terminally extended; Sequence=AAI10875.1; Type=Erroneous initiation; Note=Translation N-terminally

shortened; Sequence=BAB55357.1; Type=Erroneous initiation; Note=Translation N-terminally extended;

Sequence=BAC11493.1; Type=Erroneous initiation; Note=Translation N-terminally extended;

1 PDB 3D structure from and Proteopedia for MUM1:

3PMI (3D)

Secondary accessions: A1L489 B5ME02 Q13109 Q5XKB9 Q8N2I4 Q96A67

Alternative splicing: 2 isoforms: Q2TAK8-1 Q2TAK8-2

Explore the universe of human proteins at neXtProt for MUM1: NX_Q2TAK8

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q2TAK8

MUM1 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_116242.2

ENSEMBL proteins:

ENSP00000466891 ENSP00000467287 ENSP00000468557 ENSP00000468322 ENSP00000467083

ENSP00000465838 ENSP00000394925 ENSP00000345789 ENSP00000309135

Human Recombinant Protein Products for MUM1:

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	Uscn Proteins for MUM1

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IDA	--

MUM1 for ontologies About GeneDecksing

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	Uscn ELISAs and CLIAs for MUM1

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

MUM1 for domains About GeneDecksing

1 InterPro domain/family:

IPR000313 PWWP

Graphical View of Domain Structure for InterPro Entry Q2TAK8

ProtoNet protein and cluster: Q2TAK8

UniProtKB/Swiss-Prot: MUM1_HUMAN, Q2TAK8

Domain: The PWWP domain mediates the interaction with nucleosomes

Similarity: Belongs to the MUM1 family

Similarity: Contains 1 PWWP domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: MUM1_HUMAN, Q2TAK8

Function: Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture.

Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin

changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage

Genatlas biochemistry entry for MUM1:

multiple myeloma oncogene 1,same as IRF4,overexpressed in myeloma with translocation t(6;14)(p25;q32)

Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005515	protein binding	IPI	--
GO:0031491	nucleosome binding	IDA	--

MUM1 for ontologies About GeneDecksing

Phenotypes:
1 GenomeRNAi human phenotype for MUM1:

Increased G1 DNA content

Animal Models:

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for MUM1

miRNA Products:		OriGene 3'-UTR Clone: MUM1 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MUM1
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		SwitchGear 3'UTR luciferase reporter plasmid: MUM1 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MUM1 (see all 7) OriGene shRNA RFP: MUM1 OriGene siRNA: MUM1
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		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MUM1 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MUM1 (see all 2) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MUM1

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for MUM1

STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

4 Interacting proteins for MUM1 (Q2TAK8³ ENSP00000345789⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
DMAP1	Q9NPF5³	I2D: score=1
HIST2H3C	ENSP00000358154⁴	STRING: ENSP00000358154
TRAF2	ENSP00000247668⁴	STRING: ENSP00000247668
ELAVL1	ENSP00000385269⁴	STRING: ENSP00000385269

About this table

Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006281	DNA repair	IMP	--
GO:0006325	chromatin organization	IMP	--

MUM1 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for MUM1
Search CenterWatch for drugs/clinical trials and news about MUM1

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for MUM1 gene:

NM_032853.3

Unigene Cluster for MUM1:

Melanoma associated antigen (mutated) 1

Hs.515016 [show with all ESTs]

Unigene Representative Sequence: NR_024247

18 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000592374 ENST00000588351 ENST00000591337 ENST00000590866 ENST00000588810

ENST00000591433 ENST00000591806 ENST00000587460 ENST00000415183(uc010dsi.2)

ENST00000590695 ENST00000586996 ENST00000585399 ENST00000586067 ENST00000591627

ENST00000591453 ENST00000588888 ENST00000344663(uc002lrz.2 uc010xgm.1 uc002lsd.2)

ENST00000311401(uc002lsb.2 uc002lsc.1)

miRNA Products:		OriGene 3'-UTR Clone: MUM1 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MUM1
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Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
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		Sirion Biotech Custom design and validation of potent shRNA sequences against MUM1

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MUM1 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MUM1 (see all 2) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MUM1
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MUM1

Additional cDNA sequence:

AF151045.1 AK025936.1 AK075241.1 AK309092.1 AL360266.1 BC001806.1 BC008098.1 BC019585.1

BC021016.1 BC082987.1 BC110874.1 BC130443.1 BC144138.1 BC144147.1 CR457395.1 NR_024247.1

U20896.1 U20897.1

23 DOTS entries:

DT.121495026 DT.100749543 DT.310602 DT.121495056 DT.121494893 DT.97796015 DT.121495111 DT.40106483

DT.97808070 DT.95378836 DT.97811164 DT.86856171 DT.121494943 DT.92426166 DT.92426168 DT.95264281

DT.121494903 DT.121494925 DT.40192158 DT.91757739 DT.95078688 DT.121494979 DT.75178837

24/225 AceView cDNA sequences (see all 225):

BQ919253 BE502869 BQ184135 N21175 BQ936799 BC008098 BM697775 BF940515

AI673110 BU734337 BG413461 BM704888 BE669475 AI554518 AW300750 BM477708

AI302147 AW514373 BM678586 BM980372 BQ958626 BU623021 CA944662 BM823773

GeneLoc Exon Structure

5/15 Alternative Splicing Database (ASD) splice patterns (SP) for MUM1 (see all 15) About this scheme

ExUns:	1a	·	1b	^	2	^	3	^	4a	·	4b	^	5a	·	5b	·	5c	^	6a	·	6b	^	7a	·	7b	·	7c	·	7d	·	7e	·	7f	^	8	^	9	^	10	^	11	^	12	^	13	^	14	^	15a	·	15b	^
SP1:
SP2:
SP3:
SP4:											-		-		-						-
SP5:											-		-		-				-		-

ExUns:	16	^	17a	·	17b	^	18	^	19a	·	19b	·	19c
SP1:
SP2:
SP3:	-		-				-
SP4:
SP5:

ECgene alternative splicing isoforms for MUM1

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

MUM1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GTTTTGTGGG

About this image

MUM1 expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

1 LifeMap In Vivo Development Anatomical Compartment/Cell

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Neural Tube

Mesencephalic Ventricular Zone

Neural Tube

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See MUM1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for MUM1

SOURCE GeneReport for Unigene cluster: Hs.515016

SABiosciences Custom PCR Arrays for MUM1

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MUM1 Browse OriGene validated miRNA SYBR primer pairs
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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MUM1

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MUM1

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for MUM1 gene from 4/10 species (see all 10) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Mum1^{1 , 5}	melanoma associated antigen (mutated) 1^{1, 5}	68.65(n)¹ 64.19(a)¹		10 (39.72 cM)⁵ 68114¹ NM_023431.5¹ NP_075920.4¹ 80226434⁵
chicken (Gallus gallus)	Aves	GGA.7377⁶	Uncharacterized protein	37(a)	1 → many	28(2510984-2517868)
tropical clawed frog (Xenopus tropicalis)	Amphibia	Str.2407²	Transcribed sequence with strong similarity to protein more	69.08(n)		AL957114.2
zebrafish (Danio rerio)	Actinopterygii	si:dkey-127k13.1⁶ si:dkey-57k2.7⁶	si:dkey-57k2.7	16(a) 14(a)	many ↔ many many ↔ many	2(37170127-37182556) 2(37181473-37183295)

ENSEMBL Gene Tree for MUM1 (if available)
TreeFam Gene Tree for MUM1 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for MUM1 gene

MUM1L1²

2 SIMAP similar genes for MUM1 using alignment to 10 protein entries: MUM1_HUMAN (see all proteins):

MUM-1 MUM1L1

MUM1 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 19 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs66477374^1,2	C,F	--	1353104(+)	`AGGCGA/GTATGT`	1	--	us2k¹		8		NA WA CSA EA	368
rs181392086^1,2		--	1353171(+)	`TTTAAC/TGTGAG`	1	--	us2k¹		0	--	--	--	--
rs139068695^1,2		--	1353208(+)	`AACCAC/TCCACA`	1	--	us2k¹		0	--	--	--	--
rs185531035^1,2		--	1353347(+)	`CAGCAC/TAGCAA`	1	--	us2k¹		0	--	--	--	--
rs144061042^1,2		--	1353423(+)	`ACTCCA/GGAGGC`	1	--	us2k¹		0	--	--	--	--
rs114770105^1,2	F	--	1353473(+)	`GCAGTG/AAGCTA`	1	--	us2k¹		1		WA	118
rs190685268^1,2		--	1353536(+)	`AAATGC/TAAATA`	1	--	us2k¹		0	--	--	--	--
rs145973927^1,2		--	1353677(+)	`TAGAGC/TCGGCT`	1	--	us2k¹		0	--	--	--	--
rs8113375^1,2	A	--	1353878(+)	`aatagC/Ttggga`	1	--	us2k¹		0	--	--	--	--
rs182920378^1,2		--	1353893(+)	`AGGCAA/TCGCCA`	1	--	us2k¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for MUM1 (1285890 - 1378430 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for MUM1
2 CNVs: 7191 4066
1 Inversion: 37201

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MUM1

DNA2.0 Custom Variant and Variant Library Synthesis for MUM1

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

MUM1 for disorders About GeneDecksing

6 diseases for MUM1: About MalaCards

melanoma b-cell lymphomas hodgkin's lymphoma multiple myeloma

mediastinitis myeloma

1 disease from the University of Copenhagen DISEASES database for MUM1:

Diffuse large B-cell lymphoma

Export disorders for MUM1 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for MUM1 gene, integrated from 9 sources (see all 21):
(articles sorted by number of sources associating them with MUM1)

Utopia: connect your pdf to the dynamic
world of online information

A mutated intron sequence codes for an antigenic peptide recognized by cytolytic T lymphocytes on a human melanoma. (PubMed id 7644523)^{1, 2, 3} Coulie P.G.... Boon T. (1995)
Regulation of chromatin architecture by the PWWP domain-containing DNA damage-responsive factor EXPAND1/MUM1. (PubMed id 20347427)^{1, 2} Huen M.S.... Chen J. (2010)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)^{1, 3} Zhang Q.-H.... Chen Z. (2000)
MUM-1 expression differentiates tumors in the PEComa f amily from clear cell sarcoma and melanoma. (PubMed id 21903680)¹ Ferenczi K....Zhang P.J. (2012)
[Significance of MUM-1/IRF4 protein expression in foll icular lymphoma]. (PubMed id 22169641)¹ Huo Y.Y....Meng B. (2011)
Structural and histone binding ability characterizations of human PWWP domains. (PubMed id 21720545)¹ Wu H.... Min J. (2011)
Immunohistochemical expression of Mum-1, Oct-2 and Bcl -6 in systemic anaplastic large cell lymphomas. (PubMed id 22158496)¹ Saglam A. and Uner A.H. (2011)
A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)¹ Wagner S.A....Choudhary C. (2011)
[Correlation between the expressions of CARMA1 gene an d MUM1 and its significance in diffuse large B cell lymphoma]. (PubMed id 21569705)¹ Chen Y.M....Zhong Y. (2011)

(in PubMed, OMIM, and NCBI Bookshelf)
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 84939	HGNC: 29641	AceView: MUM1	Ensembl:ENSG00000160953	euGenes: HUgn84939
ECgene: MUM1	H-InvDB: MUM1

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for MUM1	Pharmacogenomics, SNPs, Pathways
ATLAS Chromosomes in Cancer entry for MUM1	Genetics and Cytogenetics in Oncology and Haematology

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Patent Information for MUM1 gene:
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melanoma associated antigen (mutated) 1

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melanoma associated antigen (mutated) 1

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