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Aliases for MUCL1 Gene

Aliases for MUCL1 Gene

  • Mucin-Like 1 2 3
  • Small Breast Epithelial Mucin 2 3 4
  • SBEM 3 4 6
  • Mucin-Like Protein 1 3
  • Protein BS106 4

External Ids for MUCL1 Gene

Previous GeneCards Identifiers for MUCL1 Gene

  • GC12P053539
  • GC12P055248
  • GC12P052287

Summaries for MUCL1 Gene

UniProtKB/Swiss-Prot for MUCL1 Gene

  • May play a role as marker for the diagnosis of metastatic breast cancer.

Gene Wiki entry for MUCL1 Gene

No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MUCL1 Gene

Genomics for MUCL1 Gene

Regulatory Elements for MUCL1 Gene

Genomic Location for MUCL1 Gene

54,830,519 bp from pter
54,858,393 bp from pter
27,875 bases
Plus strand

Genomic View for MUCL1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MUCL1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MUCL1 Gene

Proteins for MUCL1 Gene

  • Protein details for MUCL1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Mucin-like protein 1
    Protein Accession:
    Secondary Accessions:
    • Q0VG95
    • Q32ZB5

    Protein attributes for MUCL1 Gene

    90 amino acids
    Molecular mass:
    9039 Da
    Quaternary structure:
    No Data Available

neXtProt entry for MUCL1 Gene

Proteomics data for MUCL1 Gene at MOPED

Post-translational modifications for MUCL1 Gene

  • O-glycosylated.
  • Glycosylation at Thr23, Thr24, Thr30, Thr34, Thr46, Thr47, Thr51, Thr52, Thr54, Thr55, Thr59, Thr60, Thr62, Thr63, Ser66, Thr67, and Thr68

Other Protein References for MUCL1 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for MUCL1 Gene

Domains for MUCL1 Gene

Protein Domains for MUCL1 Gene


Suggested Antigen Peptide Sequences for MUCL1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MUCL1: view

No data available for Gene Families and UniProtKB/Swiss-Prot for MUCL1 Gene

Function for MUCL1 Gene

Molecular function for MUCL1 Gene

UniProtKB/Swiss-Prot Function: May play a role as marker for the diagnosis of metastatic breast cancer.

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for MUCL1

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MUCL1 Gene

Localization for MUCL1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for MUCL1 Gene

Secreted. Membrane.

Subcellular locations from

Jensen Localization Image for MUCL1 Gene COMPARTMENTS Subcellular localization image for MUCL1 gene
Compartment Confidence
extracellular 4
golgi apparatus 4

Gene Ontology (GO) - Cellular Components for MUCL1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IEA --
GO:0005796 Golgi lumen TAS --
GO:0016020 membrane IEA --
genes like me logo Genes that share ontologies with MUCL1: view

Pathways for MUCL1 Gene

genes like me logo Genes that share pathways with MUCL1: view

Interacting Proteins for MUCL1 Gene

Gene Ontology (GO) - Biological Process for MUCL1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006493 protein O-linked glycosylation TAS --
GO:0016266 O-glycan processing TAS --
GO:0043687 post-translational protein modification TAS --
GO:0044267 cellular protein metabolic process TAS --
genes like me logo Genes that share ontologies with MUCL1: view

Transcripts for MUCL1 Gene

Unigene Clusters for MUCL1 Gene

Mucin-like 1:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for MUCL1

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MUCL1 Gene

No ASD Table

Relevant External Links for MUCL1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MUCL1 Gene

mRNA expression in normal human tissues for MUCL1 Gene

mRNA differential expression in normal tissues according to GTEx for MUCL1 Gene

This gene is overexpressed in Skin - Sun Exposed (Lower leg) (21.5), Skin - Not Sun Exposed (Suprapubic) (18.6), and Breast - Mammary Tissue (11.4).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for MUCL1 Gene

SOURCE GeneReport for Unigene cluster for MUCL1 Gene Hs.348419

mRNA Expression by UniProt/SwissProt for MUCL1 Gene

Tissue specificity: Expressed in mammary, salivary glands and prostate. Also detected in lung. Mainly expressed in cancer cell lines of breast origin. Highly expressed in lymph node-positive compared with node-negative tumors. Detected in all lymph node containing metastatic cells.
genes like me logo Genes that share expressions with MUCL1: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery for MUCL1 Gene

Orthologs for MUCL1 Gene

This gene was present in the common ancestor of human and mouse.

Orthologs for MUCL1 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia MUCL1 35
  • 95.19 (n)
  • 93.33 (a)
MUCL1 36
  • 99 (a)
(Mus musculus)
Mammalia Mucl1 16
Species with no ortholog for MUCL1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MUCL1 Gene

Gene Tree for MUCL1 (if available)
Gene Tree for MUCL1 (if available)

Paralogs for MUCL1 Gene

No data available for Paralogs for MUCL1 Gene

Variants for MUCL1 Gene

Polymorphic Variants from UniProtKB/Swiss-Prot for MUCL1 Gene

The number of repeats varies from 3 to 2 in one variant form which is equally present in breast cancer tumors

Sequence variations from dbSNP and Humsavar for MUCL1 Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type MAF
rs979523 -- 54,853,059(+) GGACC(A/T)CTTAG upstream-variant-2KB
rs979524 -- 54,853,465(+) ATATT(C/T)TACAT upstream-variant-2KB
rs1048371 -- 54,854,573(+) CTTCA(G/T)GTCAC utr-variant-5-prime
rs1349908 -- 54,853,067(+) TAGCA(C/T)GTTTT upstream-variant-2KB
rs1349909 -- 54,853,296(+) AGGCC(G/T)CAGTT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MUCL1 Gene

Variant ID Type Subtype PubMed ID
nsv516882 CNV Gain 19592680

Relevant External Links for MUCL1 Gene

HapMap Linkage Disequilibrium report

Disorders for MUCL1 Gene

MalaCards: The human disease database

MalaCards: The human disease database. (1) Diseases for MUCL1 Gene including...

Search for MUCL1 Gene in MalaCards »

(7) Novoseek inferred disease relationships for MUCL1 Gene

Disease -log(P) Hits PubMed IDs
breast cancer 50.2 27
breast cancer metastatic 45.6 1
carcinoma ductal 44.5 2
primary tumor 27.2 2
cancer 22.4 5
genes like me logo Genes that share disorders with MUCL1: view

No data available for UniProtKB/Swiss-Prot for MUCL1 Gene

Publications for MUCL1 Gene

  1. Identification of a novel breast- and salivary gland-specific, mucin- like gene strongly expressed in normal and tumor human mammary epithelium. (PMID: 12019145) Miksicek R.J. … Leygue E. (Cancer Res. 2002) 2 3 4 23
  2. Identification of MGB1 as a marker in the differential diagnosis of lung tumors in patients with a history of breast cancer by analysis of publicly available SAGE data. (PMID: 15096563) Koga T. … Yatabe Y. (J. Mol. Diagn. 2004) 3 4 23
  3. Human small breast epithelial mucin: the promise of a new breast tumor biomarker. (PMID: 15684711) Hube F. … Myal Y. (DNA Cell Biol. 2004) 3 4 23
  4. Serological identification of breast cancer-related antigens from a Saccharomyces cerevisiae surface display library. (PMID: 15880534) Wadle A. … Renner C. (Int. J. Cancer 2005) 3 4 23
  5. Identification of an octamer-binding site controlling the activity of the small breast epithelial mucin gene promoter. (PMID: 16720387) HubAc F. … Myal Y. (Front. Biosci. 2006) 3 23

Products for MUCL1 Gene

Sources for MUCL1 Gene

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