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Aliases for MUC3B Gene

Aliases for MUC3B Gene

  • Mucin 3B, Cell Surface Associated 2 3
  • Intestinal Mucin-3B 3 4
  • MUC-3B 3 4
  • Intestinal Mucin MUC3B 3
  • Mucin 3B 2
  • MUC3A 3
  • MUC3 3

External Ids for MUC3B Gene

Previous GeneCards Identifiers for MUC3B Gene

  • GC07P099084
  • GC07P100147
  • GC07P100160
  • GC07P100158
  • GC07P100191
  • GC07P100332
  • GC07P100547
  • GC07Pg99965
  • GC07Pg99966

Summaries for MUC3B Gene

GeneCards Summary for MUC3B Gene

MUC3B (Mucin 3B, Cell Surface Associated) is a Protein Coding gene. Among its related pathways are Diseases associated with O-glycosylation of proteins and Defective GALNT12 causes colorectal cancer 1 (CRCS1).

UniProtKB/Swiss-Prot for MUC3B Gene

  • Major glycoprotein component of a variety of mucus gels. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces (By similarity).

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MUC3B Gene

Genomics for MUC3B Gene

Genomic Location for MUC3B Gene

Chromosome:
7
Orientation:
Unknown strand

Genomic View for MUC3B Gene


Cytogenetic band:
GeneLoc Logo Gene Density

No data available for Regulatory Elements and RefSeq DNA sequence for MUC3B Gene

Proteins for MUC3B Gene

  • Protein details for MUC3B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9H195-MUC3B_HUMAN
    Recommended name:
    Mucin-3B
    Protein Accession:
    Q9H195
    Secondary Accessions:
    • Q6W762
    • Q7LDU5
    • Q9GZZ2
    • Q9UN95

    Protein attributes for MUC3B Gene

    Size:
    1237 amino acids
    Molecular mass:
    131402 Da
    Quaternary structure:
    No Data Available

neXtProt entry for MUC3B Gene

Proteomics data for MUC3B Gene at MOPED

Post-translational modifications for MUC3B Gene

No data available for DME Specific Peptides for MUC3B Gene

Domains & Families for MUC3B Gene

Gene Families for MUC3B Gene

HGNC:

Protein Domains for MUC3B Gene

InterPro:
Blocks:
ProtoNet:

Suggested Antigen Peptide Sequences for MUC3B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9H195

UniProtKB/Swiss-Prot:

MUC3B_HUMAN :
  • Contains 1 EGF-like domain.
Domain:
  • Contains 1 EGF-like domain.
  • Contains 1 SEA domain.
genes like me logo Genes that share domains with MUC3B: view

Function for MUC3B Gene

Molecular function for MUC3B Gene

UniProtKB/Swiss-Prot Function:
Major glycoprotein component of a variety of mucus gels. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces (By similarity).

Phenotypes for MUC3B Gene

GenomeRNAi human phenotypes for MUC3B:
genes like me logo Genes that share phenotypes with MUC3B: view

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MUC3B Gene

Localization for MUC3B Gene

Subcellular locations from UniProtKB/Swiss-Prot for MUC3B Gene

Membrane; Single-pass membrane protein.

Gene Ontology (GO) - Cellular Components for MUC3B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005796 Golgi lumen TAS --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with MUC3B: view

No data available for Subcellular locations from COMPARTMENTS for MUC3B Gene

Drugs & Compounds for MUC3B Gene

(2) Drugs for MUC3B Gene - From: Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials

(1) Additional Compounds for MUC3B Gene - From: Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
genes like me logo Genes that share compounds with MUC3B: view

Expression for MUC3B Gene

mRNA expression in normal human tissues for MUC3B Gene

Protein differential expression in normal tissues from HIPED for MUC3B Gene

This gene is overexpressed in Heart (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for MUC3B Gene



mRNA Expression by UniProt/SwissProt for MUC3B Gene

Q9H195-MUC3B_HUMAN
Tissue specificity: Fetal and adult small intestine and fetal and adult colon.
genes like me logo Genes that share expression patterns with MUC3B: view

Protein tissue co-expression partners for MUC3B Gene

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA differential expression in normal tissues for MUC3B Gene

Orthologs for MUC3B Gene

No data available for Orthologs and Evolution for MUC3B Gene

Paralogs for MUC3B Gene

(3) SIMAP similar genes for MUC3B Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with MUC3B: view

No data available for Paralogs for MUC3B Gene

Variants for MUC3B Gene

Sequence variations from dbSNP and Humsavar for MUC3B Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
VAR_029507 -
VAR_029508 -

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Relevant External Links for MUC3B Gene

Disorders for MUC3B Gene

Relevant External Links for MUC3B

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MUC3B

No disorders were found for MUC3B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MUC3B Gene

Publications for MUC3B Gene

  1. Multiple transcripts of MUC3: evidence for two genes, MUC3A and MUC3B. (PMID: 10973822) Pratt W.S. … Swallow D.M. (Biochem. Biophys. Res. Commun. 2000) 2 3 4 23 67
  2. Initiation of transcription of the MUC3A human intestinal mucin from a TATA-less promoter and comparison with the MUC3B amino terminus. (PMID: 12958310) Gum J.R. Jr. … Kim Y.S. (J. Biol. Chem. 2003) 3 23
  3. Associations of distinct variants of the intestinal mucin gene MUC3A with ulcerative colitis and Crohn's disease. (PMID: 11289722) Kyo K. … Nakamura Y. (J. Hum. Genet. 2001) 3 23
  4. Expression of beta-catenin and its mechanism of delocalization in intestinal-type early gastric cancer based on mucin expression. (PMID: 19475529) Lee S.H. … Park d.o. .Y. (Histol. Histopathol. 2009) 23
  5. Expression of mucin 3 and mucin 5AC in arthritic synovial tissue. (PMID: 18163520) Volin M.V. … Koch A.E. (Arthritis Rheum. 2008) 3

Products for MUC3B Gene

Sources for MUC3B Gene

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