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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

MUC3A Gene

protein-coding   GIFtS: 51
GCID: GC07P100550          (predicted)

mucin 3A, cell surface associated

(Previous names: mucin 3A, intestinal )
(Previous symbol: MUC3)
 Explore 37 diseases affiliated with
MUC3A via our new
 Human Malady Compendium 
Biological research products
for MUC3A
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Mucin 3A, Cell Surface Associated1 2     Mucin 3, Intestinal2
MUC31 2 3     Mucin-3A1
Mucin 3A, Intestinal1 2     Intestinal Mucin-3A3
MUC-3A2 3     

External Ids:    HGNC: 75131   Entrez Gene: 45842   Ensembl: ENSG000001698947   OMIM: 1583715   UniProtKB: Q025053   

Export aliases for MUC3A gene to outside databases

Previous GC identifers: GC07U990056 GC07P100161 GC07P100196 GC07Ph99598 GC07Ph99599 GC07Ph99600 GC07P100385 GC07P100549


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for MUC3A:
The mucin genes encode epithelial glycoproteins, some of which are secreted and some membrane bound. Each of the genes
contains at least one large domain of tandemly repeated sequence that encodes the peptide sequence rich in serine
and/or threonine residues, which carries most of the O-linked glycosylation (Gendler and Spicer, 1995 (PubMed
7778880)).(supplied by OMIM, Aug 2008)

UniProtKB/Swiss-Prot: MUC3A_HUMAN, Q02505
Function: Major glycoprotein component of a variety of mucus gels. Thought to provide a protective, lubricating barrier
against particles and infectious agents at mucosal surfaces. May be involved in ligand binding and intracellular
signaling

Gene Wiki entry for MUC3A


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NT_007933.15  NT_079596.2  NC_018918.1  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for MUC3A
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for MUC3A

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MUC3A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q22   Ensembl cytogenetic band:  7q22.1   HGNC cytogenetic band: 7q22.1

MUC3A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MUC3A gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07P100550:  view genomic region     (about GC identifiers)

Start:
100,547,187 bp from pter      End:
100,611,619 bp from pter
Size:
64,433 bases      Orientation:
plus strand

1 alternative location:
Chr7+,CRA_TCAG 99,964,572-99,969,297     

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: MUC3A_HUMAN, Q02505 (See protein sequence)
Recommended Name: Mucin-3A precursor  
Size: 2541 amino acids; 265918 Da
Subcellular location: Isoform 1: Membrane; Single-pass membrane protein
Subcellular location: Isoform 2: Secreted
Subcellular location: Isoform 3: Secreted
Subcellular location: Isoform 4: Secreted
Subcellular location: Isoform 5: Secreted
Secondary accessions: O14650 O14651 O43418 O43421 Q02506 Q6W763 Q9H3Q7 Q9UKW9 Q9UN93 Q9UN94 Q9UN95
Alternative splicing: 5 isoforms:  Q02505-1   Q02505-2   Q02505-3   Q02505-4   Q02505-5   

Explore the universe of human proteins at neXtProt for MUC3A: NX_Q02505

Post-translational modifications:

  • Highly O-glycosylated and probably also N-glycosylated1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q02505

  • MUC3A Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).


    ENSEMBL proteins: 
     ENSP00000324834   ENSP00000393306   ENSP00000406404  
    Reactome Protein details: Q02505
    Human Recombinant Protein Products: 
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    Uscn Proteins for MUC3A

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region NAS9334251
    GO:0005796Golgi lumen TAS--
    GO:0016021integral to membrane NAS10512748


    MUC3A for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    MUC3A for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR000082 SEA
     IPR000742 EG-like_dom
     IPR013032 EGF-like_CS

    Graphical View of Domain Structure for InterPro Entry Q02505

    ProtoNet protein and cluster: Q02505

    UniProtKB/Swiss-Prot: MUC3A_HUMAN, Q02505
    Similarity: Contains 1 EGF-like domain
    Similarity: Contains 1 SEA domain


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: MUC3A_HUMAN, Q02505
    Function: Major glycoprotein component of a variety of mucus gels. Thought to provide a protective, lubricating barrier
    against particles and infectious agents at mucosal surfaces. May be involved in ligand binding and intracellular
    signaling

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    Inhib. RNA
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    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005201extracellular matrix structural constituent NAS10405327
    GO:0030197extracellular matrix constituent, lubricant activity NAS9334251


    MUC3A for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for MUC3A:
     Increased gamma-H2AX phosphory 


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Addition of GalNAc to the Tn antigen via an alpha-1,6 linkage forms a Core 7 glycoprotein
    Addition of GalNAc to the Tn antigen via an alpha-1,6 linkage forms a Core 7 glycoprotein1.00
    Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein1.00
    Addition of galactose to the Tn antigen via an alpha-1,3 linkage forms a Core 8 glycoprotein1.00
    Termination of O-glycan biosynthesis0.69
    Addition of GlcNAc to the Tn antigen via an alpha-1,3 linkage forms a Core 5 glycoprotein1.00
    O-linked glycosylation of mucins0.28
    2Asparagine N-linked glycosylation
    Post-translational protein modification0.44
    Metabolism of proteins0.15

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    5/8        Reactome Pathways for MUC3A (see all 8)
        Addition of GalNAc to the Tn antigen via an alpha-1,6 linkage forms a Core 7 glycoprotein
    O-linked glycosylation of mucins
    Metabolism of proteins
    Post-translational protein modification
    Addition of galactose to the Tn antigen via an alpha-1,3 linkage forms a Core 8 glycoprotein



    MUC3A for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for MUC3A

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/46 Interacting proteins for MUC3A (Q025053 ENSP000003248344) via UniProtKB, MINT, STRING, and/or I2D (see all 46)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MYCP011063, ENSP000003672074I2D: score=1 STRING: ENSP00000367207
    TFF3Q076543I2D: score=1 
    GALNT1ENSP000002691954STRING: ENSP00000269195
    GALNT13ENSP000003765704STRING: ENSP00000376570
    MUC1ENSP000003389834STRING: ENSP00000338983
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007586digestion NAS--
    GO:0016266O-glycan processing TAS--
    GO:0030277maintenance of gastrointestinal epithelium NAS--
    GO:0043687post-translational protein modification TAS--
    GO:0044267cellular protein metabolic process TAS--


    MUC3A for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    MUC3A for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for MUC3A
    10/11 Novoseek chemical compound relationships for MUC3A gene (see all 11)    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    cesium chloride 53.2 1 14550470 (1)
    periodate 38.4 1 9358856 (1)
    methotrexate 20.1 1 1511431 (1)
    oligonucleotide 12.5 2 8604237 (1), 11775866 (1)
    galactose 7.77 3 8135773 (1)
    estrogen 0.67 3 15737028 (1), 9650551 (1), 15255542 (1)
    cholesterol 0 3 12517055 (2), 14634353 (1)
    steroid 0 4 9650551 (2), 15255542 (2)
    calcium 0 2 12517055 (2)
    progesterone 0 3 15255542 (2), 15737028 (1)

    Search CenterWatch for drugs/clinical trials and news about MUC3A 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    Unigene Clusters for MUC3A:

    Mucin 3A, cell surface associated
    Hs.744422  [show with all ESTs], Hs.744530  [show with all ESTs]
    Unigene Representative Sequences: AF007194, AW842071
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000483366 ENST00000483133(uc003uxk.1 uc003uxl.1 uc010lhn.1)
    ENST00000319509 ENST00000414964 ENST00000422757 ENST00000480291

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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MUC3A

    Additional cDNA sequence: 

    M55405.1 M55406.1 

    12 DOTS entries:

    DT.100777667  DT.40127976  DT.100777668  DT.95276628  DT.95082764  DT.95229658  DT.95276625  DT.97809569 
    DT.99937929  DT.100707915  DT.91650020  DT.92417973 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    MUC3A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CAGGGCTTCA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See MUC3A Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for MUC3A

    SOURCE GeneReport for Unigene clusters: Hs.744422 Hs.744530

    UniProtKB/Swiss-Prot: MUC3A_HUMAN, Q02505
    Tissue specificity: Broad specificity; small intestine, colon, colonic tumors, heart, liver, thymus, prostate, pancreas
    and gall bladder

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for MUC3A gene from 5/18 species (see all 18)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    lizard
    (Anolis carolinensis)
    Reptilia MUC46
    --
    7(a)
    1 ↔ 1
    GL344173.1(54-12003)
    zebrafish
    (Danio rerio)
    Actinopterygii znf1856
    zinc finger protein 185 (LIM domain)
    3(a)
    1 ↔ 1
    14(18522903-18543174)
    fruit fly
    (Drosophila melanogaster)
    Insecta Muc96D1 Mucin 96D 43.35(n)
    31.02(a)
      318737  NM_170227.2  NP_733106.2 
    worm
    (Caenorhabditis elegans)
    Secernentea clec-2236
    C-type LECtin family member (clec-223)
    5(a)
    1 ↔ 1
    V(11273130-11278141)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes DAN41 Dan4p 42.21(n)
    32.49(a)
      853616   NP_012685.1 


    ENSEMBL Gene Tree for MUC3A (if available)
    TreeFam Gene Tree for MUC3A (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for MUC3A gene
    LOC1001315142  MUC162  MUC122  MUC172  MUC222  
    4 SIMAP similar genes for MUC3A using alignment to 8 protein entries:     MUC3A_HUMAN (see all proteins):
    LOC100131514    MUC3B    MUC3    MUC12

    MUC3A for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for MUC3A
    PGOHUM00000250959 PGOHUM00000250960


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1144 NCBI SNPs in MUC3A are shown (see all 1144    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs731637931,2
    C,,other99967168(+) TCCCTT/CTGGTG 2 /L syn12Minor allele frequency- C:0.25NA 4
    rs776677881,2
    C,F,,--99909117(+) TCTCAT/AGTGCC 2 /Q /H mis12Minor allele frequency- A:0.50NA 4
    rs769513011,2
    C,F,--99909121(+) AAGTGC/ACTTTC 2 /T /P mis12Minor allele frequency- A:0.50NA 4
    rs776262051,2
    C--99909135(+) AGAGCG/AGAAGC 2 /A syn11Minor allele frequency- A:0.50NA 2
    rs737142281,2
    C,F,,--99909519(+) CAGAAG/ACCAGT 2 /K syn12Minor allele frequency- A:0.50WA NA 4
    rs769546331,2
    C--99909817(+) TCACTC/TCCACA 2 P S mis10--------
    rs777536781,2
    C,F,--99909852(+) ACCGCC/ATCCCA 2 /A syn11Minor allele frequency- A:0.12EU 343
    rs777096941,2
    --99909858(+) TCCCAC/GCCCAC 2 H Q mis10--------
    rs785313991,2
    C,--99909862(+) AGCCCA/CCAGCC 2 T P mis10--------
    rs715409141,2
    C--99909876(+) AATACG/ATTGTC 2 /T syn12Minor allele frequency- A:0.25NA 4

    HapMap Linkage Disequilibrium report for MUC3A (100547187 - 100611619 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for MUC3A: --
    Human Gene Mutation Database (HGMD): MUC3A

    SABiosciences Cancer Mutation PCR Assays
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    DNA2.0 Custom Variant and Variant Library Synthesis for MUC3A

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    MUC3A for disorders           About GeneDecksing

    OMIM gene information: 158371    OMIM disorders: --

    20/37 diseases for MUC3A (see all 37):    About MalaCards
    peutz-jeghers syndrome    renal clear cell carcinoma    treacher collins syndrome    inflammatory bowel disease
    barrett's esophagus    cystic fibrosis    colonic polyps    ulcerative colitis
    cholecystitis    gastroduodenitis    renal cell carcinoma    carcinoma
    colon cancer    ovarian cancer    adenocarcinoma    fibrosis
    breast carcinoma    colorectal cancer    crohn's disease    colon adenocarcinoma

    1 disease from the University of Copenhagen DISEASES database for MUC3A:
    Cystic fibrosis

    10/30 Novoseek disease relationships for MUC3A gene (see all 30)    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    metaplasia 56.1 10 11093805 (1), 11101634 (1), 7678777 (1), 11775866 (1) (see all 6)
    adenocarcinoma 51.9 6 15737028 (1), 8859775 (1), 11076872 (1), 11274635 (1) (see all 5)
    colitis ulcerative 46.8 2 8813081 (1), 9931338 (1)
    neoplastic transformation 44.4 1 11775866 (1)
    carcinoma bronchioloalveolar 42.7 2 11274635 (2)
    renal clear cell carcinoma 42.3 6 14550470 (3), 12010365 (1)
    dysplasia 42.1 8 16949933 (2), 8859775 (1), 9334836 (1), 11076872 (1)
    inflammatory bowel diseases 41.6 1 8813081 (1)
    colon cancer 41.6 10 8813081 (2), 7678777 (2), 8020672 (2), 1728605 (1) (see all 5)
    gastric carcinoma 39.6 8 12719460 (4), 11775866 (2), 10592051 (1), 15737028 (1)

    Genetic Association Database (GAD): MUC3A

    Export disorders for MUC3A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for MUC3A gene, integrated from 9 sources (see all 113):
    (articles sorted by number of sources associating them with MUC3A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Multiple transcripts of MUC3: evidence for two genes, MUC3A and MUC3B. (PubMed id 10973822)1, 2, 3 Pratt W.S....Swallow D.M. (2000)
    2. Molecular cloning of cDNAs derived from a novel human intestinal mucin gene. (PubMed id 2393399)1, 2, 3 Gum J.R. Jr.... Kim Y.S. (1990)
    3. MUC3 human intestinal mucin. Analysis of gene structure, the carboxyl terminus, and a novel upstream repetitive region. (PubMed id 9334251)1, 2, 9 Gum J.R. Jr.... Kim Y.S. (1997)
    4. The MUC3 gene encodes a transmembrane mucin and is alternatively spliced. (PubMed id 10405327)1, 2, 9 Williams S.J.... McGuckin M.A. (1999)
    5. Initiation of transcription of the MUC3A human intestinal mucin from a TATA-less promoter and comparison with the MUC3B amino terminus. (PubMed id 12958310)1, 2 Gum J.R. Jr.... Kim Y.S. (2003)
    6. The DNA sequence of human chromosome 7. (PubMed id 12853948)1, 2 Hillier L.W.... Wilson R.K. (2003)
    7. Associations of distinct variants of the intestinal mucin gene MUC3A with ulcerative colitis and Crohn's disease. (PubMed id 11289722)1, 2 Kyo K.... Nakamura Y. (2001)
    8. Genomic organization and structure of the 3' region of human MUC3: alternative splicing predicts membrane-bound and soluble forms of the mucin. (PubMed id 10512748)1, 2 Crawley S.C.... Kim Y.S. (1999)
    9. Quantitative RT-PCR assay for MUC3 and VEGF mRNA in renal clear cell carcinoma: relationship with nuclear grade and prognosis. (PubMed id 14550470)1, 9 Leroy X....Porchet N. (2003)
    10. Association of ulcerative colitis with rare VNTR alleles of the human intestinal mucin gene, MUC3. (PubMed id 9931338)4, 9 Kyo K....Nakamura Y. (1999)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 4584 HGNC: 7513 Ensembl:ENSG00000169894 euGenes: HUgn4584 ECgene: MUC3A
    H-InvDB: MUC3A

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for MUC3A Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for MUC3A Genetics and Cytogenetics in Oncology and Haematology
    Mucin databasehttp://www.medkem.gu.se/mucinbiology/databases/

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for MUC3A gene:
    Search GeneIP for patents involving MUC3A

    GeneCards and IP:
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