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MUC21 Gene

protein-coding   GIFtS: 44
GCID: GC06P030951

Mucin 21, Cell Surface Associated

(Previous name: chromosome 6 open reading frame 205)
(Previous symbol: C6orf205)
  Search for MUC21
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Mucin 21, Cell Surface Associated1 2     KMQK6972
C6orf2051 2 3     bCX31G15.22
epiglycanin1 2     mucin-212
MUC-212 3     Epiglycanin3
Chromosome 6 Open Reading Frame 2051     

External Ids:    HGNC: 216611   Entrez Gene: 3942632   Ensembl: ENSG000002045447   UniProtKB: Q5SSG83   

Export aliases for MUC21 gene to outside databases

Previous GC identifers: GC06P031060 GC06P030751


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for MUC21 Gene:
MUC21 (mucin 21, cell surface associated) is a protein-coding gene. An important paralog of this gene is MUC22.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NT_167246.2  NT_167248.2  NC_000006.11  NC_018917.2  NT_007592.16  NT_113891.3  NT_167244.2  NT_167245.2  
NT_167247.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the MUC21 gene promoter:
         TBP   STAT1   AML1a   C/EBPalpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMUC21 promoter sequence
   Search Chromatin IP Primers for MUC21

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MUC21


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p21.32   Ensembl cytogenetic band:  6p21.33   HGNC cytogenetic band: 6p21.33

MUC21 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MUC21 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06P030951:  view genomic region     (about GC identifiers)

Start:
30,951,485 bp from pter      End:
30,957,680 bp from pter
Size:
6,196 bases      Orientation:
plus strand

Selected alternative locations (see all 8):
Chr6+,NT_167244 2,263,124-2,269,309      Chr6+,ALT_REF_LOCI_6 30,941,073-30,947,468      Chr6+,ALT_REF_LOCI_4 30,996,174-31,002,464     
Chr6+,NT_167245 2,245,596-2,251,781      Chr6+,NT_113891.2 2,463,385-2,469,585      Chr6+,NT_167248 2,244,470-2,250,860     

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: MUC21_HUMAN, Q5SSG8 (See protein sequence)
Recommended Name: Mucin-21 precursor  
Size: 566 amino acids; 54228 Da
Miscellaneous: Could be considered as a marker for lung carcinomas
Sequence caution: Sequence=AAI05737.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: B0UZT7 B4DQ55 C9JMK2 D9N007 Q0VGF1 Q3B7T2 Q5SS94 Q6UXC5
Alternative splicing: 3 isoforms:  Q5SSG8-1   Q5SSG8-2   Q5SSG8-3   

Explore the universe of human proteins at neXtProt for MUC21: NX_Q5SSG8

Explore proteomics data for MUC21 at MOPED

Post-translational modifications: 

  • O-glycosylated1
  • Glycosylation2 at Asn25
  • Modification sites at PhosphoSitePlus

  • See MUC21 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_001010909.2  
    ENSEMBL proteins: 
     ENSP00000457640   ENSP00000365473  
    Reactome Protein details: Q5SSG8

    MUC21 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
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    Browse OriGene Protein Over-expression Lysates
    OriGene Custom MassSpec
    OriGene Custom Protein Services for MUC21
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    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for MUC21

     
    Search eBioscience for Proteins for MUC21 

    MUC21 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for MUC21
    Novus Biologicals MUC21 Antibody
    Search for Antibodies for MUC21 at Abcam
    Cloud-Clone Corp. Antibodies for MUC21
    Search ThermoFisher Antibodies for MUC21
    Search LSBio for Antibodies for MUC21

    MUC21 Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for MUC21
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for MUC21
    Cloud-Clone Corp. CLIAs for MUC21
    Search eBioscience for ELISAs for MUC21 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    MUC: Mucins

    2 InterPro protein domains:
     IPR008519 Tandem-repeating_mucin
     IPR028199 Mucin_dom

    Graphical View of Domain Structure for InterPro Entry Q5SSG8

    ProtoNet protein and cluster: Q5SSG8


    Find genes that share domains with MUC21           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for MUC21
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for MUC21

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for MUC21
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for MUC21

    miRNA
    Products:
        
    miRTarBase miRNAs that target MUC21:
    hsa-mir-17-5p (MIRT050861)

    Block miRNA regulation of human, mouse, rat MUC21 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate MUC21 (see all 9):
    hsa-miR-623 hsa-miR-1290 hsa-miR-4318 hsa-miR-4290 hsa-miR-1270 hsa-miR-320e hsa-miR-620 hsa-miR-1264
    SwitchGear 3'UTR luciferase reporter plasmidMUC21 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for MUC21
    Predesigned siRNA for gene silencing in human, mouse, rat MUC21

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for MUC21

    Clone
    Products:
         
    OriGene clones in human, mouse for MUC21 (see all 4)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: MUC21 (NM_001010909)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MUC21
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MUC21

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for MUC21
    Browse ESI BIO Cell Lines and PureStem Progenitors for MUC21 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MUC21


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    MUC21_HUMAN, Q5SSG8: Cell membrane; Single-pass type I membrane protein; Extracellular side
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane5
    golgi apparatus4
    extracellular2
    endoplasmic reticulum1
    lysosome1
    mitochondrion1
    peroxisome1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005796Golgi lumen TAS--
    GO:0005886plasma membrane IEA--
    GO:0016021integral component of membrane IEA--

    Find genes that share ontologies with MUC21           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for MUC21 About    
    See pathways by source

    SuperPathContained pathways About
    1O-linked glycosylation of mucins
    O-linked glycosylation of mucins0.47
    Termination of O-glycan biosynthesis0.38
    2Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
    Post-translational protein modification0.43
    Metabolism of proteins0.30


    Find genes that share SuperPaths with MUC21           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    2 Reactome Pathways for MUC21
        O-linked glycosylation of mucins
    Termination of O-glycan biosynthesis


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for MUC21
    Interactions:

        Search GeneGlobe Interaction Network for MUC21

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016266O-glycan processing TAS--
    GO:0043687post-translational protein modification TAS--
    GO:0044267cellular protein metabolic process TAS--

    Find genes that share ontologies with MUC21           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for MUC21



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for MUC21 gene: 
    NM_001010909.2  

    Unigene Cluster for MUC21:

    Mucin 21, cell surface associated
    Hs.448277  [show with all ESTs]
    Unigene Representative Sequence: NM_001010909
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000486149 ENST00000376296(uc003nsh.2 uc003nsi.1 uc021yuf.1)

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat MUC21 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate MUC21 (see all 9):
    hsa-miR-623 hsa-miR-1290 hsa-miR-4318 hsa-miR-4290 hsa-miR-1270 hsa-miR-320e hsa-miR-620 hsa-miR-1264
    SwitchGear 3'UTR luciferase reporter plasmidMUC21 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for MUC21
    Predesigned siRNA for gene silencing in human, mouse, rat MUC21
    Clone
    Products:
         
    OriGene clones in human, mouse for MUC21 (see all 4)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: MUC21 (NM_001010909)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MUC21
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MUC21
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for MUC21
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat MUC21
      QuantiTect SYBR Green Assays in human, mouse, rat MUC21
      QuantiFast Probe-based Assays in human, mouse, rat MUC21

    Additional mRNA sequence: 

    AB242595.1 AK056612.1 AK298642.1 AK299471.1 AK301645.1 AK316363.1 AY358415.1 BC105735.1 
    BC105736.1 BC105737.1 BC107478.1 HM596784.1 

    4 DOTS entries:

    DT.99976641  DT.95300203  DT.95122412  DT.121344318 

    6 AceView cDNA sequences:

    AK056612 AL602765 BU733613 AL703190 CD696619 AY358415 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    MUC21 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GAGCCCCCCA
    MUC21 Expression
    About this image

    MUC21 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    MUC21 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.448277

    UniProtKB/Swiss-Prot: MUC21_HUMAN, Q5SSG8
    Tissue specificity: Expressed in lung, large intestine, thymus, and testis. Expressed in normal and malignant
    bronchial epithelial cells

        Custom PCR Arrays for MUC21
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for MUC21
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat MUC21
    QuantiTect SYBR Green Assays in human, mouse, rat MUC21
    QuantiFast Probe-based Assays in human, mouse, rat MUC21
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MUC21

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of human and mouse.

    Orthologs for MUC21 gene from Selected species (see all 2)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Gm95735 predicted gene 9573   --   17 (18.70 cM) 35617923 


    ENSEMBL Gene Tree for MUC21 (if available)
    TreeFam Gene Tree for MUC21 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for MUC21 gene
    MUC222  

    Find genes that share paralogs with MUC21           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for MUC21 (see all 365)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1491946431,2
    C,Funtested130954327(+) GAGTCC/TAGCAC 2 S syn11Minor allele frequency- T:0.01EU 955
    rs1439898441,2
    Cuntested130954489(+) AGCACA/TGCCAC 2 T syn11Minor allele frequency- T:0.00EU 937
    rs737271471,2
    C--30949492(+) AATACG/AAATTA 1 -- us2k11Minor allele frequency- A:0.50WA 2
    rs25174251,2
    C,F,H--30949670(-) ATAGCA/CCTCTA 1 -- us2k127Minor allele frequency- C:0.16NS EA NA WA CSA 2905
    rs1445985061,2
    C--30949828(+) ACACCA/GCTGAC 1 -- us2k10--------
    rs1140786191,2
    C,F--30949829(+) CACCGC/GTGACC 1 -- us2k11Minor allele frequency- G:0.02WA 118
    rs1915113061,2
    --30949875(+) TTCATA/GTCTTC 1 -- us2k10--------
    rs1146306551,2
    C,F--30949937(+) AGCTCG/TTTCGC 1 -- us2k11Minor allele frequency- T:0.03WA 118
    rs25174241,2
    C,F,A,H--30949996(-) CCCCAA/TCAATG 1 -- us2k117Minor allele frequency- T:0.22NS EA MN NA WA 1610
    rs28446781,2
    C,F,H--30950050(-) TTTAAC/TAACCA 1 -- us2k124Minor allele frequency- T:0.13NS EA MN NA WA 2792

    HapMap Linkage Disequilibrium report for MUC21 (30951485 - 30957680 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 8 variations for MUC21:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2670269CNV Deletion23128226
    esv2731799CNV Deletion23290073
    esv2731800CNV Deletion23290073
    esv2677358CNV Deletion23128226
    esv2731791CNV Deletion23290073
    esv5663CNV Loss19470904
    dgv6535n71CNV Loss21882294
    nsv462744CNV Loss19166990

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing MUC21
    DNA2.0 Custom Variant and Variant Library Synthesis for MUC21

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    1 disease from the University of Copenhagen DISEASES database for MUC21:
    Breast carcinoma

    Find genes that share disorders with MUC21           About GenesLikeMe

    Genetic Association Database (GAD): MUC21
    Human Genome Epidemiology (HuGE) Navigator: MUC21 (2 documents)

    Export disorders for MUC21 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for MUC21 gene, integrated from 10 sources (see all 18):
    (articles sorted by number of sources associating them with MUC21)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification and expression of human epiglycanin/MUC21: a novel transmembrane mucin. (PubMed id 17977904)1, 2, 3 Itoh Y.... Irimura T. (Glycobiology 2008)
    2. Genome-wide association study of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in Europe. (PubMed id 21801394)1, 4 GAcnin E....Mockenhaupt M. (Orphanet J Rare Dis 2011)
    3. High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions. (PubMed id 19851445)1, 4 Barcellos L.F....Criswell L.A. (PLoS Genet. 2009)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (Genome Res. 2003)
    6. Genome-Wide Association Study of Pre-Eclampsia Detects Novel Maternal Single Nucleotide Polymorphisms and Copy-Number Variants in Subsets of the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study Cohort. (PubMed id 23551011)1 Zhao L....Dewan A.T. (Ann. Hum. Genet. 2013)
    7. GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children. (PubMed id 23263863)1 Li J....Sleiman P.M. (Hum. Mol. Genet. 2013)
    8. Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function. (PubMed id 23284291)1 Hancock D.B....London S.J. (PLoS Genet. 2012)
    9. Novel associations for hypothyroidism include known autoimmune risk loci. (PubMed id 22493691)4 Eriksson N....Do C.B. (PLoS ONE 2012)
    10. Multiple loci are associated with white blood cell phenotypes. (PubMed id 21738480)1 Nalls M.A....Ganesh S.K. (PLoS Genet. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 394263 HGNC: 21661 AceView: C6orf205 Ensembl:ENSG00000204544 euGenes: HUgn394263
    ECgene: MUC21 H-InvDB: MUC21

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for MUC21 Pharmacogenomics, SNPs, Pathways
    Mucin databasehttp://www.medkem.gu.se/mucinbiology/databases/

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for MUC21 gene:
    Search GeneIP for patents involving MUC21

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    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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     Block miRNA regulation of human, mouse, rat MUC21 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing MUC21
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