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MUC2 Gene

protein-coding   GIFtS: 66

GC11P001064
mucin 2, oligomeric mucus/gel-forming
(Previous names: mucin 2, intestinal/tracheal )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
Services    

Aliases &
Descriptions
for MUC2

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section
Aliases
MLP 2
MUC-2 3
SMUC 2, 3
Descriptions
Intestinal mucin-2 3
mucin 2 2
mucin 2, intestinal/tracheal 1, 2
mucin 2, oligomeric mucus/gel-forming 2
mucin-like protein 2
External Ids
HGNC: 75121
Entrez Gene: 45832
UniProtKB: Q028173
Ensembl: ENSG000001987887
Search outside databases for aliases for MUC2 gene

Previous GC identifers: GC11U990088 GC11M000095 GC11P001072

Summaries
for MUC2

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

 EntrezGene summary for MUC2:
This gene encodes a member of the mucin protein family. Mucins are high molecular weight
glycoproteins produced by many epithelial tissues. The protein encoded by this gene is secreted
and forms an insoluble mucous barrier that protects the gut lumen. The protein polymerizes into a
gel of which 80% is composed of oligosaccharide side chains by weight. The protein features a
central domain containing tandem repeats rich in threonine and proline that varies between 50 and
115 copies in different individuals. Alternatively spliced transcript variants of this gene have
been described, but their full-length nature is not known. [provided by RefSeq]

UniProtKB/Swiss-Prot: MUC2_HUMAN, Q02817
Function: Coats the epithelia of the intestines, airways, and other mucus membrane-containing
organs. Thought to provide a protective, lubricating barrier against particles and infectious
agents at mucosal surfaces. Major constituent of both the inner and outer mucus layers of the
colon and may play a role in excluding bacteria from the inner mucus layer

Gene Wiki entry for MUC2

Genomic Location
for MUC2

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

 Genomic View:
UCSC Golden Path with GeneCards custom track

 Transcription factor binding sites upstream to the MUC2 gene  

Entrez Gene cytogenetic band: 11p15.5   Ensembl cytogenetic band:  11p15.5   HGNC cytogenetic band: 11p15.5

MUC2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11P001064:     (about GC identifiers)

Start:
 1,064,875 bp from pter
End:
 1,094,419 bp from pter
Size:
 29,545 bases
Orientation:
 plus strand
RefSeq DNA sequence:
NC_000011.8  NT_035113.6  

Proteins
for MUC2

(According to 1UniProtKB, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

 UniProtKB/Swiss-Prot: MUC2_HUMAN, Q02817 (See protein sequence)
Recommended Name: Mucin-2 precursor  
Size: 5179 amino acids; 540300 Da
Subunit: Homotrimer; disulfide-linked. Dimerizes in the endoplasmic reticulum via its C-terminal
region and polymerizes via its N-terminal region by disulfide-linked trimerization. Interacts with
FCGBP
Subcellular location: Secreted
Secondary accessions: Q14878

Post-translational modifications:

  • O-glycosylated1
  • May undergo proteolytic cleavage in the outer mucus layer of the colon, contributing to the
    expanded volume and loose nature of this layer which allows for bacterial colonization in contrast
    to the inner mucus layer which is dense and devoid of bacteria (By similarity)1
  • At low pH of 6 and under, undergoes autocatalytic cleavage in vitro in the N-terminal region of the
    fourth VWD domain. It is likely that this also occurs in vivo and is triggered by the low pH of
    the late secretory pathway1
  • View phosphorylation sites using PhosphoSite2


    • REFSEQ proteins: NP_002448.2  

    ENSEMBL proteins: 
    ENSP00000331373 ENSP00000354885 ENSP00000351956 


    Human Recombinant Proteins 
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    Browse recombinant and purified proteins available from Enzo Life Sciences
    Recombinant Proteins from Abcam (pan Mucin, MUC2)
    Browse Abnova for Human Recombinant Proteins
                    Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 

    1 Gene Ontology (GO) cellular component term (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576 extracellular region IEA--
    About this table

    Antibodies for MUC2: 
    Invitrogen Antibodies for MUC2
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    Antibodies from Abcam (pan Mucin, MUC2), each with their AbpromiseSM
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    Novus Biologicals Antibodies for MUC2

    Assays for MUC2: 
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    Protein Domains/
    Families
    for MUC2

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    5/7 InterPro domains/families (see all 7 ):
     IPR014853 Conserved-cysteine-rich_domain
     IPR006552 VWC_out
     IPR006207 Cys_knot_C
     IPR013032 EGF-like_reg_CS
     IPR001007 VWF_C


       GeneDecks  MUC2 for the domains selected above  
    About GeneDecksing

    Graphical View of Domain Structure for InterPro Entry Q02817

    ProtoNet protein and cluster: Q02817

    5/6 Blocks protein families (see all 6 ):
    IPB001007 von Willebrand factor
    IPB001846 Von Willebrand factor
    IPB002400 Growth factor cystine knot superfamily signature
    IPB002919 Trypsin inhibitor-like
    IPB006207 Cystine knot


    UniProtKB/Swiss-Prot: MUC2_HUMAN, Q02817
    Similarity: Contains 1 CTCK (C-terminal cystine knot-like) domain
    Similarity: Contains 1 TIL (trypsin inhibitory-like) domain
    Similarity: Contains 2 VWFC domains
    Similarity: Contains 4 VWFD domains

    Gene Function
    for MUC2

    (According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
    RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section
    Inhib.
    RNA:    		Invitrogen RNAi Products for gene knock-down (MUC2)
    Browse for Gene Knock-down Tools from Millipore
    Abnova Chimera RNAi Products for Gene knock-down (MUC2)
                  OriGene 29mer shRNA kit in GFP-retroviral vector: NM_002457

                  Applied Biosystems Silencer® siRNAs for MUC2

                  Sigma-Aldrich siRNA for MUC2  
                         Sigma-Aldrich shRNA Panels and shRNA for MUC2  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Clones:Browse Clone Ranger at Invitrogen for clones
    Browse Clones for the Expression of Recombinant Proteins Available from Millipore
                  OriGene GFP tagged cDNA clone in CMV expression vector: NM_002457
                                     Myc/DDK tagged cDNA clone in CMV expression vector: NM_002457
                                     untagged cDNA clone in CMV expression vector: NM_002457 

    Primers: Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
                  OriGene genome-wide validated SYBR primer pairs: NM_002457

    UniProtKB/Swiss-Prot: MUC2_HUMAN, Q02817
    Function: Coats the epithelia of the intestines, airways, and other mucus membrane-containing
    organs. Thought to provide a protective, lubricating barrier against particles and infectious
    agents at mucosal surfaces. Major constituent of both the inner and outer mucus layers of the
    colon and may play a role in excluding bacteria from the inner mucus layer

    Genatlas biochemistry entry for MUC2:
    mucin 2,intestinal,glycoprotein of membrane,belonging to the secreted mucins cluster,involved in
    epithelial cell differentiation,expressed in epithelial ovarian cancer,in normal urothelium and in
    bladder cancer

    4 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for Muc2):

    cellulardigestive/alimentarytumorigenesis

    Pathways & Interactions
    for MUC2

    (Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
    Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section


    1 Kegg Pathway  (Kegg details for MUC2):
     hsa05110 Vibrio cholerae infection

       GeneDecks  MUC2 for the pathways selected above  
    About GeneDecksing
     Gene Network CentralTM Interacting Genes and Proteins Network for  MUC2 


    5/38 Interacting proteins for MUC2 (ENSP000003519563) via UniProtKB, MINT, and/or STRING (see all 38 )
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CHPFENSP000002437763STRING (score=.982)
    SMAD4ENSP000003415513STRING (score=.97)
    CDX2ENSP000003704083STRING (score=.953)
    CDX1ENSP000002316563STRING (score=.948)
    RELAENSP000003115083STRING (score=.945)
    About this table

    Drugs & Compounds
    for MUC2

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section

    Browse drugs & compounds from Enzo Life Sciences
    Browse Small Molecules at Sigma-Aldrich

    Browse Tocris compounds for MUC2
    10/19 Novoseek chemical compound relationships for MUC2 gene (see all 19 )
    Compound   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
    cesium chloride 53.27 1 19246635 (1)
    deoxycholic acid 44.81 14 17576890 (4), 19014523 (3), 15754327 (1), 16385573 (1)
    threonine 35.72 15 19246635 (6), 9722984 (1), 9195982 (1), 10578046 (1) (see all 5)
    crcs 32.78 13 11051251 (4), 17951204 (2), 12555994 (1)
    pd 98,059 22.47 4 12482999 (1), 18176092 (1), 12077118 (1), 12391274 (1)
    proline 21.86 3 9195982 (1), 1892319 (1)
    oligonucleotide 20.96 5 11673830 (1), 8604237 (1), 8997274 (1), 11775866 (1) (see all 5)
    hpaii 20.80 2 12527922 (1), 9426407 (1)
    hematoxylin 12.49 1 10633292 (1)
    sialic acid 11.42 6 9147071 (2), 10394884 (2), 17640971 (1)
    About this table


    Transcripts
    for MUC2

    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Invitrogen, Millipore, and/or Abnova,
    siRNAs from Applied Biosystems, Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene,
    Tagged/untagged cDNA clones from OriGene,
    Expression Assays from Applied Biosystems)
    About This Section
    Inhib.
    RNA:    		Invitrogen RNAi Products for gene knock-down (MUC2)
    Browse for Gene Knock-down Tools from Millipore
    Abnova Chimera RNAi Products for Gene knock-down (MUC2)
                  OriGene 29mer shRNA kit in GFP-retroviral vector: NM_002457

                  Sigma-Aldrich siRNA for MUC2  
                         Sigma-Aldrich shRNA Panels and shRNA for MUC2  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Applied Biosystems Silencer® siRNAs: 

    NM_002457  

    REFSEQ mRNAs for MUC2 gene: 

    NM_002457.2   

    Applied Biosystems TaqMan ® Gene Expression Assays: 

    NM_002457  

                  OriGene GFP tagged cDNA clone in CMV expression vector: NM_002457
                                     Myc/DDK tagged cDNA clone in CMV expression vector: NM_002457
                                     untagged cDNA clone in CMV expression vector: NM_002457 

    Additional cDNA sequence: 

    AF257167.1 L21998.1 M22405.1 M86523.1 M94131.1 M94132.1 

    8 DOTS entries:

    DT.109216  DT.97835062  DT.95107578  DT.95375324  DT.120693040  DT.87004723  DT.120693023  DT.121004091 

    24/75 AceView cDNA sequences (see all 75 ):

    M94132 BM769184 BX506293 BX950907 CA433871 AI346844 AW604941 AI983400 
    AW849961 AI832475 AI991841 M86523 AA327452 BM988311 CA433774 AI672920 
    CD614857 AI991308 AI749252 AI732350 AI677743 BQ083982 AW001371 BX505925 

    highest scoring ESTs for MUC2:

    AA327059 AA327452 AA523410 AA534503 AA857748 AI246778 AI281892 AI346844 AI475425 AI672920 

    Unigene Cluster for MUC2:

    Mucin 2, oligomeric mucus/gel-forming
    Hs.315  [show with all ESTs]
    Unigene Representative Sequence: NM_002457


    GeneLoc Exon Structure

    3 Ensembl transcripts including schematic representations:
    ENST00000333592  ENST00000361558  ENST00000359061  

    Expression
    for MUC2

    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Expression Assays from Applied Biosystems )
    About This Section

    MUC2 expression in normal and diseased human tissues

     Applied Biosystems TaqMan ® Gene Expression Assays for MUC2

    1 / 2 / 3

    4 probe-sets matching MUC2 gene


    		Affymetrix
    probe-set    		 Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank

    		896_at2, 3 U95-A 1 1.00 1.00 0.83 1.21 L21998 0.80 1.00 0.91 1

    		733_at2, 3 U95-A 1 1.00 1.00 0.88 0.83 HG2149-HT2219 0.20 1.00 0.72 1

    		204673_at2, 3 U133-A 1 1.00 1.00 -- -- NM_002457 0.40 1.00 0.76 1

    		204673_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
    About this table
    Data from (Publications) and GNF BioGPS
        About these images
    About these images

    CGAP SAGE TAG: TACTCGGCCA

    SOURCE GeneReport for Unigene cluster: Hs.315

    Expression variation in blood from EXPOLDB for MUC2

    UniProtKB/Swiss-Prot: MUC2_HUMAN, Q02817
    Tissue specificity: Colon, small intestine, colonic tumors, bronchus, cervix and gall bladder

    Orthologs
    for MUC2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section
    Orthologs for MUC2 gene from 5 species
    Organism Gene Locus Description Human
    Similarity    		 NCBI accessions
    dog
    (Canis familiaris)    		 MUC21   -- mucin 2, oligomeric mucus/gel-forming 85.15(n)
    83.7(a)    		 483653  XM_540774.2  XP_540774.2 
    chimpanzee
    (Pan troglodytes)    		 MUC21   -- mucin 2, oligomeric mucus/gel-forming 83.8(n)
    79.92(a)    		 450941  XM_508211.2  XP_508211.2 
    mouse
    (Mus musculus)    		 Muc25
    LOC1000396491    		 7 (68.99 cM)5
    		 mucin 25
    similar to secreted gel-forming mucin1    		 83.06(n)1
    82.6(a)1    		 1000396491  XM_001473263.11  XP_001473313.11 
     AF0166955  AF0805845  (see all 18)
    chicken
    (Gallus gallus)    		 MUC21   -- mucin 2, oligomeric mucus/gel-forming 57.06(n)
    53.98(a)    		 423101  XM_421035.2  XP_421035.2 
    fruit fly
    (Drosophila melanogaster)    		 Hml3 70C4 defense response sugar binding 28(a)   --
    About this table        Species with no ortholog for MUC2

    ENSEMBL Gene Tree for MUC2

    Paralogs
    for MUC2

    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section

    Paralogs for MUC2 gene
    VWF2  MUC62  

    SNPs/Variants
    for MUC2

    (According to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
    About This Section

    		UniProtKB/Swiss-Prot: MUC2_HUMAN, Q02817
    Polymorphism: The number of repeats is highly polymorphic and varies among different alleles


    10/619 NCBI SNPs in MUC2 are shown (see all 619 )
    (Click for Applied Biosystems TaqMan ® Genotyping Assay)  (see all 112)
    ABGenomic DataTranscription DataAllele Frequencies
    SNP IDValidChr 11 posSequenceRecsAA
    Chg    		TypeMoreRecsAllele
    freq    		PopTotal
    sample    		More
    ------------
    rs20711751,2
    		A,C,F,H1064401(+) GCCCTC/TGGGGA 1 -- ng514Minor allele frequency- T:0.35EU EA WA 380
    rs79277651,2
    		A,C,F,H1094626(-) CATTTC/TGACAG 1 -- ng3112Minor allele frequency- T:0.29EU EA WA 1256
    rs118259771,2
    		A,C,F,H1065920(+) GGGCCG/ATGTGA 1 M/V mis1 ese36Minor allele frequency- A:0.15EU EA WA NA 602
    rs28561111,2
    		A,C,F,H1065747(+) CGGCCT/CCTGCG 1 P/L mis1 ese34Minor allele frequency- C:0.38EU EA WA 392
    rs71264051,2
    		A,C,F,H1093296(-) GCATCA/GAAGTT 2 Q/P Q/L mis17Minor allele frequency- G:0.18NA EU EA WA 552
    rs74805631,2
    		A,C,F,H1091649(-) TAGNAG/AGGNGA 2 P/T S/T mis1 ese36Minor allele frequency- A:0.29EU EA WA NA 594
    rs64219721,2
    		A,C,F,H1086494(-) CGGGGG/ACAGGA 1 T/I mis1 ese38Minor allele frequency- A:0.16EU EA WA 838
    rs20711741,2
    		A,C,F,H1063712(+) GTCTCT/CATAAC 1 -- ng519Minor allele frequency- C:0.47EA EU WA NA 2090
    rs20711731,2
    		A,C,F1063378(+) GGCCCG/ACCTGG 1 -- ng511Minor allele frequency- A:0.47EA 1492
    rs112459361,2
    		C,F,H1074362(+) CTTCCG/AGCGCC 1 S/G mis1 ese38Minor allele frequency- A:0.05EU EA WA 840
    About this table

    HapMap Linkage Disequilibrium images for MUC2 (up to first 250kb)

    Disorders & Mutations
    for MUC2

    (in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
    About This Section

    		 OMIM: 158370

    10/91 Novoseek disease relationships for MUC2 gene (see all 91 )

    Disease   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
    carcinoma mucinous 84.42 42 12493022 (4), 9306958 (4), 15378790 (2), 18487999 (2) (see all 26)
    metaplasia 81.29 76 17559374 (4), 16545139 (3), 10633292 (3), 10583575 (3) (see all 37)
    adenocarcinoma 76.88 99 15252308 (3), 18487999 (3), 17991319 (3), 12877727 (3) (see all 56)
    gastric carcinoma 74.05 66 17559374 (4), 15378790 (3), 15737028 (3), 14758553 (3) (see all 35)
    pseudomyxoma peritonei 71.90 13 12218214 (6), 12163380 (6)
    carcinoma 70.62 98 11893907 (4), 15272531 (4), 10227723 (3), 11420467 (3) (see all 55)
    adenoma 64.20 46 10424888 (4), 9215126 (3), 12820724 (3), 12210083 (2) (see all 24)
    carcinoma signet ring cell 63.46 1 19102008 (1)
    adenocarcinoma tubular 62.59 3 15378790 (1), 19102008 (1)
    barrett esophagus 60.02 8 16259110 (1), 16995451 (1), 16336609 (1), 12152167 (1) (see all 8)
    About this table

    1 PharmGKB disease relationship for MUC2 gene
    Disease PharmGKB Relations PubMed IDs for articles supporting these relationships
    Colorectal NeoplasmsFA  15754327
    About this table

    Human Gene Mutation Database: MUC2
    Genetic Association Database: MUC2
    Human Genome Epidemiology Navigator: MUC2 (5 documents)

    Medical News
    for MUC2

    (Possibly Related Articles in Doctor's Guide)
    About This Section

    		   --

    Publications
    for MUC2

    (in PubMed. Associations of this gene to articles via 1Novoseek, 2HGNC, 3Entrez Gene, 4UniProtKB/Swiss-Prot, 5UniProtKB/TrEMBL, 6GAD, and/or 7PharmGKB)
    About This Section

    		10/556 PubMed articles for MUC2 gene (see all 556 ):

    Search for MUC2

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing MUC2

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
    About This Section
    Entrez Gene: 4583 HGNC: 7512 AceView: MUC2.1 Ensembl:ENSG00000198788 euGenes: HUgn4583
    ECgene: MUC2 H-InvDB: MUC2

    Other Databases showing MUC2

    (According to HUGE)
    About This Section

    		   --

    Specialized Databases showing MUC2

    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    ATLAS Chromosomes in Cancer entry for MUC2 Genetics and Cytogenetics in Oncology and Haematology
    Mucin databasehttp://www.medkem.gu.se/mucinbiology/databases/

    Licensable Technologies
    for MUC2

    (Available from WIS Yeda, Salk, Tufts)
    About This Section

    		  --

    Services
    for MUC2

    (Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
    Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
    Enzo Life Sciences, and/or Tocris Bioscience)
    About This Section



    Products for MUC2:
     TaqMan ® Gene Expression Assays
     TaqMan ® Genotyping Assays
    		  Free SNP selection tool



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     Predesigned and custom siRNAs for MUC2 Antibodies for MUC2
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     Lentivirus-delivered shRNAs for MUC2 Browse small molecules at Sigma-Aldrich
     "Your Favorite Gene" Pathwaysfeedback


      
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