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MUC17 Gene

protein-coding   GIFtS: 52
GCID: GC07P100663

Mucin 17, Cell Surface Associated

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Mucin 17, Cell Surface Associated1 2     mucin-172
Small Intestinal Mucin-32 3     Secreted Mucin MUC172
MUC-172 3     Small Intestinal Mucin MUC32
MUC-32 3     EC 3.1.38
MUC32 3     EC 6.3.2.88
Membrane Mucin MUC172     

External Ids:    HGNC: 168001   Entrez Gene: 1404532   Ensembl: ENSG000001698767   OMIM: 6084245   UniProtKB: Q685J33   

Export aliases for MUC17 gene to outside databases

Previous GC identifers: GC07P099168 GC07P100231 GC07P100235 GC07P100276 GC07P100450 GC07P100022


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for MUC17 Gene:
Membrane mucins, such as MUC17, function in epithelial cells to provide cytoprotection, maintain luminal
structure, provide signal transduction, and confer antiadhesive properties upon cancer cells that lose their
apical/basal polarization.(supplied by OMIM, Apr 2004)

GeneCards Summary for MUC17 Gene:
MUC17 (mucin 17, cell surface associated) is a protein-coding gene. Diseases associated with MUC17 include biliary papillomatosis, and bile reflux. GO annotations related to this gene include PDZ domain binding and extracellular matrix constituent, lubricant activity. An important paralog of this gene is MUC3A.

UniProtKB/Swiss-Prot: MUC17_HUMAN, Q685J3
Function: Probably plays a role in maintaining homeostasis on mucosal surfaces

Gene Wiki entry for MUC17 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000007.14  NC_018918.2  NT_007933.16  
Regulatory elements:
   Regulatory transcription factor binding sites in the MUC17 gene promoter:
         NRSF form 1   NF-kappaB   NRSF form 2   NF-kappaB1   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for MUC17

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MUC17


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q22.1   Ensembl cytogenetic band:  7q22.1   HGNC cytogenetic band: 7q22

MUC17 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MUC17 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07P100663:  view genomic region     (about GC identifiers)

Start:
100,663,353 bp from pter      End:
100,702,140 bp from pter
Size:
38,788 bases      Orientation:
plus strand

1 alternative location:
Chr7+,CRA_TCAG 100,021,753-100,060,529     

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: MUC17_HUMAN, Q685J3 (See protein sequence)
Recommended Name: Mucin-17 precursor  
Size: 4493 amino acids; 451741 Da
Subunit: Interacts via its C-terminus with PDZK1 and this interaction appears important for proper localization
Secondary accessions: O14761 Q685J2 Q8TDH7
Alternative splicing: 2 isoforms:  Q685J3-1   Q685J3-2   

Explore the universe of human proteins at neXtProt for MUC17: NX_Q685J3

Explore proteomics data for MUC17 at MOPED

Post-translational modifications: 

  • Probably cleaved within the SEA domain1
  • N-glycosylated. Contains high mannose and complex-type glycans. The forms containing the complex type glycans
    localize to the cell surface. Not O-glycosylated1
  • Glycosylation2 at Ser56, Asn471, Asn696, Asn898, Asn1345, Asn2077, Asn2194, Asn3344, Asn4116, Asn4205,
                                 Asn4236, Asn4267, Asn4297, Asn4305
  • Modification sites at PhosphoSitePlus
  • 2 DME Specific Peptides for MUC17 (Q685J3)
     EINSLST  VVTSTAV 


    See MUC17 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_001035194.1  
    ENSEMBL proteins: 
     ENSP00000302716   ENSP00000368751  
    Reactome Protein details: Q685J3

    MUC17 Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    MUC: Mucins

    3 InterPro protein domains:
     IPR000742 EG-like_dom
     IPR000082 SEA_dom
     IPR013032 EGF-like_CS

    Graphical View of Domain Structure for InterPro Entry Q685J3

    ProtoNet protein and cluster: Q685J3

    1 Blocks protein domain: IPB000082 SEA domain

    UniProtKB/Swiss-Prot: MUC17_HUMAN, Q685J3
    Similarity: Contains 1 EGF-like domain
    Similarity: Contains 1 SEA domain


    MUC17 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: MUC17_HUMAN, Q685J3
    Function: Probably plays a role in maintaining homeostasis on mucosal surfaces

         Enzyme Numbers (IUBMB): EC 3.1.32 EC 6.3.2.82

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI17990980
    GO:0030165PDZ domain binding IPI17990980
    GO:0030197extracellular matrix constituent, lubricant activity NAS9299468
         
    MUC17 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for MUC17:
     Synthetic lethal with Ras 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for MUC17
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    miRNA
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    miRTarBase miRNAs that target MUC17:
    hsa-mir-20b-5p (MIRT004712), hsa-mir-30c-5p (MIRT004714), hsa-mir-20a-5p (MIRT004711), hsa-mir-132-3p (MIRT021736), hsa-mir-30e-5p (MIRT004715), hsa-mir-17-5p (MIRT004710)

    Block miRNA regulation of human, mouse, rat MUC17 using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate MUC17:
    hsa-miR-656
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MUC17


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    MUC17_HUMAN, Q685J3: Isoform 1: Cell membrane; Single-pass membrane protein
    MUC17_HUMAN, Q685J3: Isoform 2: Secreted (Probable). Cell membrane
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane5
    extracellular4
    golgi apparatus4
    endoplasmic reticulum1
    lysosome1

    Gene Ontology (GO): 5 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region IEA--
    GO:0005796Golgi lumen TAS--
    GO:0009897external side of plasma membrane IDA12888891
    GO:0016021integral component of membrane IEA--
    GO:0016324apical plasma membrane IDA17990980

    MUC17 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for MUC17 About    
    See pathways by source

    SuperPathContained pathways About
    1O-linked glycosylation of mucins
    O-linked glycosylation of mucins0.47
    Termination of O-glycan biosynthesis0.38
    2Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
    Post-translational protein modification0.43
    Metabolism of proteins0.30

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    2 Reactome Pathways for MUC17
        O-linked glycosylation of mucins
    Termination of O-glycan biosynthesis



    MUC17 for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for MUC17
    Interactions:

        GeneGlobe Interaction Network for MUC17

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for MUC17 (ENSP000003027164) via UniProtKB, MINT, STRING, and/or I2D (see all 44)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    GALNT1ENSP000002691954STRING: ENSP00000269195
    GALNT10ENSP000002971074STRING: ENSP00000297107
    GALNT14ENSP000002889884STRING: ENSP00000288988
    GALNT15ENSP000003442604STRING: ENSP00000344260
    GCNT1ENSP000003659204STRING: ENSP00000365920
    About this table

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016266O-glycan processing TAS--
    GO:0019725cellular homeostasis TAS17990980
    GO:0043687post-translational protein modification TAS--
    GO:0044267cellular protein metabolic process TAS--

    MUC17 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for MUC17

    1 Novoseek inferred chemical compound relationship for MUC17 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    serine 21.2 1 11855812 (1)



    MUC17 for compounds           About GeneDecksing



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for MUC17 gene (2 alternative transcripts): 
    NM_001040105.1  NM_001004430.1  

    Unigene Cluster for MUC17:

    Mucin 17, cell surface associated
    Hs.271819  [show with all ESTs]
    Unigene Representative Sequence: NM_001040105
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000306151(uc003uxp.1) ENST00000379439(uc010lho.1) ENST00000470303
    ENST00000497859
    miRNA
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    hsa-miR-656
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    Additional mRNA sequence: 

    AF016692.1 AF016693.1 AF016694.1 AF430017.1 AJ606307.1 AK026404.1 BC126315.1 

    5 DOTS entries:

    DT.95357674  DT.91743183  DT.92417971  DT.435208  DT.100777667 

    Selected AceView cDNA sequences (see all 50):

    BM830721 AJ606308 NM_001004430 BM987743 BM769398 BM823649 AJ606307 BM769898 
    BM831185 BM769819 BM819089 BM843401 BM823207 BM823637 AI700389 BM773519 
    BM768498 BM823632 BM830760 BM830704 BM825521 BM831173 BM823592 AF430017 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for MUC17    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11
    SP1:                                                                  
    SP2:                          -                                       


    ECgene alternative splicing isoforms for MUC17

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    MUC17 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AAAAACACCT
    MUC17 Expression
    About this image

    MUC17 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    MUC17 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.271819

    UniProtKB/Swiss-Prot: MUC17_HUMAN, Q685J3
    Tissue specificity: Expressed almost exclusively in the intestine. Expression is especially high in both the
    duodenum and transverse colon. Expressed in mature absorptive cells of the small intestinal villi. No expression
    is detected in goblet cells. Highly expressed in pancreatic adenocarcinoma tissue (at protein level). Expression
    is not detectable in normal pancreas, in pancreatitis or in cell lines derived from other cancers

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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for MUC17 gene from Selected species (see all 7)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Muc35 mucin 3, intestinal   --   5 (76.22 cM) 137134924 
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    29(a)
    many ↔ many
    6(62094334-62111444)


    ENSEMBL Gene Tree for MUC17 (if available)
    TreeFam Gene Tree for MUC17 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for MUC17 gene
    MUC3A2  MUC122  
    2 SIMAP similar genes for MUC17 using alignment to 3 protein entries:     MUC17_HUMAN (see all proteins):
    MUC3    MUC12

    MUC17 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for MUC17 (see all 1737)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1484707781,2
    Cuntested1100681388(+) CCATGA/C/TCGGTA 2 P S mis10--------
    rs1939207841,2
    Cuntested1100683647(+) CTGGCA/GAAAGA 2 K E mis10--------
    rs1496358461,2
    Cuntested1100692191(+) TCACCG/AAAGAG 2 /K /E mis11Minor allele frequency- A:0.00NA 4550
    rs1808257191,2
    --100662782(+) GCCTCC/GTGAGT 1 -- us2k10--------
    rs1407533701,2
    --100662803(+) ACAGGC/TGCCCG 1 -- us2k10--------
    rs1449193431,2
    C--100662807(+) GCGCCC/TGCCAC 1 -- us2k10--------
    rs1479639531,2
    --100662826(+) GCTGAG/TTTTTG 1 -- us2k10--------
    rs1864039051,2
    C--100662891(+) TCATCC/TCAAGT 1 -- us2k10--------
    rs1913101411,2
    --100662893(+) ATCTCA/CAGTGA 1 -- us2k10--------
    rs69739131,2
    C,F,A,H--100662969(+) GAAGGG/ATTAGA 1 -- us2k122Minor allele frequency- A:0.33NS EA NA WA CSA 2343

    HapMap Linkage Disequilibrium report for MUC17 (100663353 - 100702140 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for MUC17 (see all 22):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2734915CNV Deletion23290073
    dgv1156e201CNV Deletion23290073
    esv2734923CNV Deletion23290073
    esv2673265CNV Deletion23128226
    esv2734888CNV Deletion23290073
    dgv1229e199CNV Deletion23128226
    dgv1157e201CNV Deletion23290073
    esv2669267CNV Deletion23128226
    esv2663086CNV Deletion23128226
    esv2734924CNV Deletion23290073

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 608424    OMIM disorders: --

    12 diseases for MUC17:    
    About MalaCards
    biliary papillomatosis    bile reflux    cholangiocarcinoma    pancreatic ductal adenocarcinoma
    intrahepatic cholangiocarcinoma    laryngitis    adenocarcinoma    pneumonia
    pancreatitis    pancreatic cancer    hypoxia    breast cancer


    MUC17 for disorders           About GeneDecksing

    7 Novoseek inferred disease relationships for MUC17 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    cholangiocarcinoma 42.2 1 8903378 (1)
    adenocarcinoma 28.8 3 12657964 (2), 8976874 (1)
    dysplasia 20.9 2 12657964 (1), 8903378 (1)
    colon cancer 20.4 1 11855812 (1)
    carcinoma 18.8 1 11422499 (1)
    cancer 8.71 2 8976874 (1), 12478674 (1)
    tumors 0 3 12657964 (3)


    Export disorders for MUC17 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for MUC17 gene, integrated from 10 sources (see all 37):
    (articles sorted by number of sources associating them with MUC17)
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    world of online information

    1. MUC17, a novel membrane-tethered mucin. (PubMed id 11855812)1, 2, 3, 9 Gum J.R. Jr.... Kim Y.S. (Biochem. Biophys. Res. Commun. 2002)
    2. The C-terminus of the transmembrane mucin MUC17 binds to the scaffold protein PDZK1 that stably localizes it to the enterocyte apical membrane in the small intestine. (PubMed id 17990980)1, 2 Malmberg E.K.... Hansson G.C. (Biochem. J. 2008)
    3. Characterization of human mucin MUC17. Complete coding sequence and organization. (PubMed id 16737958)1, 2 Moniaux N.... Batra S.K. (J. Biol. Chem. 2006)
    4. N-glycosylation is required for the surface localization of MUC17 mucin. (PubMed id 12888891)1, 2 Ho J.J.L.... Kim Y.S. (Int. J. Oncol. 2003)
    5. Molecular cloning of human MUC3 cDNA reveals a novel 59 amino acid tandem repeat region. (PubMed id 9299468)1, 2 Van Klinken B.J.-W.... Einerhand A.W. (Biochem. Biophys. Res. Commun. 1997)
    6. Human intestinal MUC17 mucin augments intestinal cell restitution and enhances healing of experimental colitis. (PubMed id 20211273)1, 9 Luu Y....Ho S.B. (amp 2010)
    7. Carbachol-induced MUC17 endocytosis is concomitant with NHE3 internalization and CFTR membrane recruitment in enterocytes. (PubMed id 23784542)1 Pelaseyed T....Hansson G.C. (Am. J. Physiol., Cell Physiol. 2013)
    8. Expression of MUC17 is regulated by HIF1I+-mediated hypoxic responses and requires a methylation-free hypoxia responsible element in pancreatic cancer. (PubMed id 22970168)1 Kitamoto S....Yonezawa S. (PLoS ONE 2012)
    9. Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation. (PubMed id 22990020)1 Huang J....Hamsten A. (Blood 2012)
    10. DNA methylation and histone H3-K9 modifications contribute to MUC17 expression. (PubMed id 20926598)1 Kitamoto S....Yonezawa S. (Glycobiology 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 140453 HGNC: 16800 AceView: MUC17 Ensembl:ENSG00000169876 euGenes: HUgn140453
    ECgene: MUC17 H-InvDB: MUC17

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for MUC17 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for MUC17 Genetics and Cytogenetics in Oncology and Haematology
    Mucin databasehttp://www.medkem.gu.se/mucinbiology/databases/

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for MUC17 gene:
    Search GeneIP for patents involving MUC17

    GeneCards and IP:
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