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Aliases for MUC1 Gene

Aliases for MUC1 Gene

  • Mucin 1, Cell Surface Associated 2 3
  • PUM 3 4 6
  • Tumor-Associated Epithelial Membrane Antigen 3 4
  • Breast Carcinoma-Associated Antigen DF3 3 4
  • Peanut-Reactive Urinary Mucin 3 4
  • Polymorphic Epithelial Mucin 3 4
  • Carcinoma-Associated Mucin 3 4
  • Mucin 1, Transmembrane 2 3
  • Krebs Von Den Lungen-6 3 4
  • Cancer Antigen 15-3 3 4
  • Episialin 3 4
  • CA 15-3 3 4
  • MCKD1 3 6
  • H23AG 3 4
  • MUC-1 3 4
  • KL-6 3 4
  • PEMT 3 4
  • EMA 3 4
  • PEM 3 4
  • Medullary Cystic Kidney Disease 1 (Autosomal Dominant) 2
  • Medullary Cystic Kidney Disease, Autosomal Dominant 3
  • Tumor Associated Epithelial Mucin 3
  • Tumor-Associated Mucin 4
  • CD227 Antigen 4
  • DF3 Antigen 3
  • H23 Antigen 3
  • MUC-1/SEC 3
  • ADMCKD1 3
  • MUC-1/X 3
  • MUC1/ZD 3
  • Mucin-1 3
  • ADMCKD 3
  • CD227 3
  • MAM6 3
  • MCKD 3
  • MCD 3

External Ids for MUC1 Gene

Previous HGNC Symbols for MUC1 Gene

  • PUM
  • MCKD1

Previous GeneCards Identifiers for MUC1 Gene

  • GC01M153036
  • GC01M150898
  • GC01M151933
  • GC01M152377
  • GC01M152378
  • GC01M151854
  • GC01M153388
  • GC01M153424
  • GC01M126521

Summaries for MUC1 Gene

Entrez Gene Summary for MUC1 Gene

  • This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2011]

GeneCards Summary for MUC1 Gene

MUC1 (Mucin 1, Cell Surface Associated) is a Protein Coding gene. Diseases associated with MUC1 include medullary cystic kidney disease 1 and cystadenocarcinoma. Among its related pathways are ERK Signaling and Adhesion. GO annotations related to this gene include p53 binding and RNA polymerase II core promoter proximal region sequence-specific DNA binding.

UniProtKB/Swiss-Prot for MUC1 Gene

  • The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack

  • The beta subunit contains a C-terminal domain which is involved in cell signaling, through phosphorylations and protein-protein interactions. Modulates signaling in ERK, SRC and NF-kappa-B pathways. In activated T-cells, influences directly or indirectly the Ras/MAPK pathway. Promotes tumor progression. Regulates TP53-mediated transcription and determines cell fate in the genotoxic stress response. Binds, together with KLF4, the PE21 promoter element of TP53 and represses TP53 activity

Gene Wiki entry for MUC1 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MUC1 Gene

Genomics for MUC1 Gene

Regulatory Elements for MUC1 Gene

Transcription factor binding sites by QIAGEN in the MUC1 gene promoter:

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for MUC1 Gene

Start:
155,185,824 bp from pter
End:
155,192,916 bp from pter
Size:
7,093 bases
Orientation:
Minus strand

Genomic View for MUC1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MUC1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MUC1 Gene

Proteins for MUC1 Gene

  • Protein details for MUC1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P15941-MUC1_HUMAN
    Recommended name:
    Mucin-1
    Protein Accession:
    P15941
    Secondary Accessions:
    • A5YRV1
    • A6ZID9
    • A6ZIE0
    • B1AVQ8
    • B1AVR0
    • B6ECA1
    • E7ESE5
    • E7EUG9
    • P13931
    • P15942
    • P17626
    • Q0VAP5
    • Q0VAP6
    • Q14128
    • Q14876
    • Q16437
    • Q16442
    • Q16615
    • Q6S4Y3
    • Q7Z547
    • Q7Z548
    • Q7Z550
    • Q7Z552
    • Q9BXA4
    • Q9UE75
    • Q9UE76
    • Q9UQL1
    • Q9Y4J2

    Protein attributes for MUC1 Gene

    Size:
    1255 amino acids
    Molecular mass:
    122102 Da
    Quaternary structure:
    • The alpha subunit forms a tight, non-covalent heterodimeric complex with the proteolytically-released beta-subunit. Interaction, via the tandem repeat region, with domain 1 of ICAM1 is implicated in cell migration and metastases. Isoform 1 binds directly the SH2 domain of GRB2, and forms a MUC1/GRB2/SOS1 complex involved in RAS signaling. The cytoplasmic tail (MUC1CT) interacts with several proteins such as SRC, CTNNB1 and ERBs. Interaction with the SH2 domain of CSK decreases interaction with GSK3B. Interacts with CTNNB1/beta-catenin and JUP/gamma-catenin and promotes cell adhesion. Interaction with JUP/gamma-catenin is induced by heregulin. Binds PRKCD, ERBB2, ERBB3 and ERBB4. Heregulin (HRG) stimulates the interaction with ERBB2 and, to a much lesser extent, the interaction with ERBB3 and ERBB4. Interacts with P53 in response to DNA damage. Interacts with KLF4. Interacts with estrogen receptor alpha/ESR1, through its DNA-binding domain, and stimulates its transcription activity. Binds ADAM17. Isoform ZD forms disulfide-linked oligomers.
    Miscellaneous:
    • The name KL-6 was originally that of a murine monoclonal antibody reacting with pulmonary adenocarcinoma cell lines and pulmonary epithelial cells. This antibody recognizes a sialylated carbohydrate chain on MUC1
    SequenceCaution:
    • Sequence=AAD14369.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305}; Sequence=AAD14376.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

    Three dimensional structures from OCA and Proteopedia for MUC1 Gene

neXtProt entry for MUC1 Gene

Proteomics data for MUC1 Gene at MOPED

Post-translational modifications for MUC1 Gene

  • Dual palmitoylation on cysteine residues in the CQC motif is required for recycling from endosomes back to the plasma membrane.
  • Highly glycosylated (N- and O-linked carbohydrates and sialic acid). O-glycosylated to a varying degree on serine and threonine residues within each tandem repeat, ranging from mono- to penta-glycosylation. The average density ranges from about 50% in human milk to over 90% in T47D breast cancer cells. Further sialylation occurs during recycling. Membrane-shed glycoproteins from kidney and breast cancer cells have preferentially sialyated core 1 structures, while secreted forms from the same tissues display mainly core 2 structures. The O-glycosylated content is overlapping in both these tissues with terminal fucose and galactose, 2- and 3-linked galactose, 3- and 3,6-linked GalNAc-ol and 4-linked GlcNAc predominating. Differentially O-glycosylated in breast carcinomas with 3,4-linked GlcNAc. N-glycosylation consists of high-mannose, acidic complex-type and hybrid glycans in the secreted form MUC1/SEC, and neutral complex-type in the transmembrane form, MUC1/TM.
  • Phosphorylated on tyrosines and serine residues in the C-terminal. Phosphorylation on tyrosines in the C-terminal increases the nuclear location of MUC1 and beta-catenin. Phosphorylation by PKC delta induces binding of MUC1 to beta-catenin/CTNNB1 and thus decreases the formation of the beta-catenin/E-cadherin complex. Src-mediated phosphorylation inhibits interaction with GSK3B. Src- and EGFR-mediated phosphorylation on Tyr-1229 increases binding to beta-catenin/CTNNB1. GSK3B-mediated phosphorylation on Ser-1227 decreases this interaction but restores the formation of the beta-cadherin/E-cadherin complex. On T-cell receptor activation, phosphorylated by LCK. PDGFR-mediated phosphorylation increases nuclear colocalization of MUC1CT and CTNNB1.
  • Proteolytic cleavage in the SEA domain occurs in the endoplasmic reticulum by an autoproteolytic mechanism and requires the full-length SEA domain as well as requiring a Ser, Thr or Cys residue at the P + 1 site. Cleavage at this site also occurs on isoform MUC1/X but not on isoform MUC1/Y. Ectodomain shedding is mediated by ADAM17.
  • The N-terminal sequence has been shown to begin at position 24 or 28.
  • Glycosylation at Thr131, Thr139, Ser140, Thr144, Asn957, Asn975, Ser989, Thr990, Ser993, Ser999, Thr1001, Thr1003, Thr1004, Ser1009, Thr1010, Asn1029, Asn1055, and Asn1133
  • Modification sites at PhosphoSitePlus

Antibody Products

  • Cell Signaling Technology (CST) Antibodies for MUC1 (MUC1)

No data available for DME Specific Peptides for MUC1 Gene

Domains for MUC1 Gene

Gene Families for MUC1 Gene

HGNC:
  • CD :CD molecules
  • MUC :Mucins

Protein Domains for MUC1 Gene

InterPro:
Blocks:
ProtoNet:

Suggested Antigen Peptide Sequences for MUC1 Gene

Graphical View of Domain Structure for InterPro Entry

P15941

UniProtKB/Swiss-Prot:

MUC1_HUMAN :
  • P15941
Domain:
  • Contains 1 SEA domain.
genes like me logo Genes that share domains with MUC1: view

Function for MUC1 Gene

Molecular function for MUC1 Gene

GENATLAS Biochemistry: mucin 1,expressed in epithelial ovarian cancer,glycoprotein of membrane,marker for the type II pneumocyte cell lineage during the proces of lung carcinogenesis,expressed in normal urothelium and in bladder cancer,in esophageal squamous cell carcinoma with poor prognosis
UniProtKB/Swiss-Prot Function: The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack
UniProtKB/Swiss-Prot Function: The beta subunit contains a C-terminal domain which is involved in cell signaling, through phosphorylations and protein-protein interactions. Modulates signaling in ERK, SRC and NF-kappa-B pathways. In activated T-cells, influences directly or indirectly the Ras/MAPK pathway. Promotes tumor progression. Regulates TP53-mediated transcription and determines cell fate in the genotoxic stress response. Binds, together with KLF4, the PE21 promoter element of TP53 and represses TP53 activity

Gene Ontology (GO) - Molecular Function for MUC1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding IDA 15710329
GO:0002039 p53 binding IPI 15710329
GO:0003712 transcription cofactor activity IDA 15710329
GO:0005515 protein binding IPI 16888623
genes like me logo Genes that share ontologies with MUC1: view
genes like me logo Genes that share phenotypes with MUC1: view

Animal Models for MUC1 Gene

MGI Knock Outs for MUC1:

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targeting and HOMER Transcription for MUC1 Gene

Localization for MUC1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for MUC1 Gene

Apical cell membrane; Single-pass type I membrane protein. Note=Exclusively located in the apical domain of the plasma membrane of highly polarized epithelial cells. After endocytosis, internalized and recycled to the cell membrane. Located to microvilli and to the tips of long filopodial protusions.
Isoform 5: Secreted.
Isoform Y: Secreted.
Isoform 9: Secreted.
Mucin-1 subunit beta: Cell membrane. Cytoplasm. Nucleus. Note=On EGF and PDGFRB stimulation, transported to the nucleus through interaction with CTNNB1, a process which is stimulated by phosphorylation. On HRG stimulation, colocalizes with JUP/gamma-catenin at the nucleus.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for MUC1 Gene COMPARTMENTS Subcellular localization image for MUC1 gene
Compartment Confidence
extracellular 5
nucleus 5
plasma membrane 5
golgi apparatus 4
cytoskeleton 2
endosome 1

Gene Ontology (GO) - Cellular Components for MUC1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000790 nuclear chromatin IDA 15710329
GO:0005615 extracellular space IDA 16502470
GO:0005737 cytoplasm --
GO:0005796 Golgi lumen TAS --
GO:0005886 plasma membrane --
genes like me logo Genes that share ontologies with MUC1: view

Pathways for MUC1 Gene

genes like me logo Genes that share pathways with MUC1: view

Pathways by source for MUC1 Gene

1 Sino Biological pathway for MUC1 Gene
2 Qiagen pathways for MUC1 Gene
1 Cell Signaling Technology pathway for MUC1 Gene
2 BioSystems pathways for MUC1 Gene

PCR Array Products

  • Pathway & Disease-focused RT² Profiler PCR Arrays

Gene Ontology (GO) - Biological Process for MUC1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001666 response to hypoxia --
GO:0001701 in utero embryonic development --
GO:0006493 protein O-linked glycosylation TAS --
GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest IDA 15710329
GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator IDA 15710329
genes like me logo Genes that share ontologies with MUC1: view

Compounds for MUC1 Gene

(83) Novoseek inferred chemical compound relationships for MUC1 Gene

Compound -log(P) Hits PubMed IDs
b 723 81.5 54
mucicarmine 80.4 10
benzyl-alpha-galnac 72.9 9
pe-10 65 4
[alcl] 64.2 12
genes like me logo Genes that share compounds with MUC1: view

Transcripts for MUC1 Gene

Unigene Clusters for MUC1 Gene

Mucin 1, cell surface associated:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for MUC1

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MUC1 Gene

ExUns: 1 ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5a · 5b ^ 6 ^ 7a · 7b ^ 8
SP1: -
SP2: - - -
SP3:
SP4:
SP5: -

Relevant External Links for MUC1 Gene

GeneLoc Exon Structure for
MUC1
ECgene alternative splicing isoforms for
MUC1

Expression for MUC1 Gene

mRNA expression in normal human tissues for MUC1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for MUC1 Gene

This gene is overexpressed in Stomach (13.2), Lung (5.9), Kidney - Cortex (4.4), and Colon - Transverse (4.2).

Integrated Proteomics: protein expression from ProteomicsDB, MOPED, and MaxQB for MUC1 Gene

SOURCE GeneReport for Unigene cluster for MUC1 Gene Hs.89603

mRNA Expression by UniProt/SwissProt for MUC1 Gene

P15941-MUC1_HUMAN
Tissue specificity: Expressed on the apical surface of epithelial cells, especially of airway passages, breast and uterus. Also expressed in activated and unactivated T-cells. Overexpressed in epithelial tumors, such as breast or ovarian cancer and also in non-epithelial tumor cells. Isoform 7 is expressed in tumor cells only.
genes like me logo Genes that share expressions with MUC1: view

In Situ Assay Products

Orthologs for MUC1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MUC1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia MUC1 35
  • 94.63 (n)
  • 94.08 (a)
MUC1 36
  • 96 (a)
OneToOne
cow
(Bos Taurus)
Mammalia MUC1 36
  • 46 (a)
OneToOne
dog
(Canis familiaris)
Mammalia MUC1 36
  • 45 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Muc1 16
Muc1 36
  • 39 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia MUC1 36
  • 34 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia MUC1 36
  • 18 (a)
OneToOne
Species with no ortholog for MUC1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MUC1 Gene

ENSEMBL:
Gene Tree for MUC1 (if available)
TreeFam:
Gene Tree for MUC1 (if available)

Paralogs for MUC1 Gene

No data available for Paralogs for MUC1 Gene

Variants for MUC1 Gene

Polymorphic Variants from UniProtKB/Swiss-Prot for MUC1 Gene

P15941-MUC1_HUMAN
The number of repeats is highly polymorphic. It varies from 21 to 125 in the northern European population. The most frequent alleles contains 41 and 85 repeats. The tandemly repeated icosapeptide underlies polymorphism at three positions: PAPGSTAP[PAQT]AHGVTSAP[DT/ES]R, DT -> ES and the single replacements P -> A, P -> Q and P-> T. The most frequent replacement DT -> ES occurs in up to 50% of the repeats

Sequence variations from dbSNP and Humsavar for MUC1 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs1131772 -- 155,191,302(-) GGCCG(C/G)CCCCG intron-variant, missense, reference
rs1611770 - 155,187,794(-) ACGAC(A/G/T)TGGAG missense, reference, intron-variant
rs1611771 -- 155,187,419(-) CCCCC(A/G)GTAGA intron-variant
rs1611772 -- 155,186,129(-) GGGCA(C/T)GTCGC utr-variant-3-prime
rs1611773 -- 155,186,056(-) CCCTG(C/T)ACCCT utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for MUC1 Gene

Variant ID Type Subtype PubMed ID
nsv464084 CNV Loss 19166990
dgv3n68 CNV Loss 17160897
dgv132e1 CNV Complex 17122850
nsv470741 CNV Loss 18288195
nsv872457 CNV Loss 21882294
nsv872458 CNV Loss 21882294
dgv390n71 CNV Loss 21882294
nsv527682 CNV Gain 19592680
nsv872460 CNV Loss 21882294
nsv2988 CNV Insertion 18451855
dgv391n71 CNV Loss 21882294
nsv872464 CNV Loss 21882294
esv1005636 CNV Insertion 20482838
esv23811 CNV Gain+Loss 19812545

Relevant External Links for MUC1 Gene

HapMap Linkage Disequilibrium report
MUC1
Human Gene Mutation Database (HGMD)
MUC1

Disorders for MUC1 Gene

(1) OMIM Diseases for MUC1 Gene (158340)

UniProtKB/Swiss-Prot

MUC1_HUMAN
  • Note=MUC1/CA 15-3 is used as a serological clinical marker of breast cancer to monitor response to breast cancer treatment and disease recurrence (PubMed:20816948). Decreased levels over time may be indicative of a positive response to treatment. Conversely, increased levels may indicate disease progression. At an early stage disease, only 21% of patients exhibit high MUC1/CA 15-3 levels, that is why CA 15-3 is not a useful screening test. Most antibodies target the highly immunodominant core peptide domain of 20 amino acid (APDTRPAPGSTAPPAHGVTS) tandem repeats. Some antibodies recognize glycosylated epitopes. {ECO:0000269 PubMed:20816948}.
  • Medullary cystic kidney disease 1 (MCKD1) [MIM:174000]: A form of tubulointerstitial nephropathy characterized by formation of renal cysts at the corticomedullary junction. It is characterized by adult onset of impaired renal function and salt wasting resulting in end-stage renal failure by the sixth decade. {ECO:0000269 PubMed:23396133}. Note=The disease is caused by mutations affecting the gene represented in this entry.

(97) Novoseek inferred disease relationships for MUC1 Gene

Disease -log(P) Hits PubMed IDs
perineurioma 89.4 20
tumors 84.8 283
carcinoma 82.5 150
sarcoma epithelioid 82.3 7
sarcoma synovial 80.6 16

Relevant External Links for MUC1

Genetic Association Database (GAD)
MUC1
Human Genome Epidemiology (HuGE) Navigator
MUC1
Tumor Gene Database (TGDB):
MUC1
genes like me logo Genes that share disorders with MUC1: view

Publications for MUC1 Gene

  1. Comparison of MUC-1 mucin expression in epithelial and non-epithelial cancer cell lines and demonstration of a new short variant form (MUC- 1/Z). (PMID: 9212228) Oosterkamp H.M. … Finstad C.L. (Int. J. Cancer 1997) 3 4 23
  2. Interaction of glycogen synthase kinase 3beta with the DF3/MUC1 carcinoma-associated antigen and beta-catenin. (PMID: 9819408) Li Y. … Kufe D. (Mol. Cell. Biol. 1998) 3 4 23
  3. High density O-glycosylation on tandem repeat peptide from secretory MUC1 of T47D breast cancer cells. (PMID: 10373415) Mueller S. … Hanisch F.-G. (J. Biol. Chem. 1999) 3 4 23
  4. The epidermal growth factor receptor regulates interaction of the human DF3/MUC1 carcinoma antigen with c-Src and beta-catenin. (PMID: 11483589) Li Y. … Kufe D. (J. Biol. Chem. 2001) 3 4 23
  5. Tyrosine phosphorylation of the MUC1 breast cancer membrane proteins. Cytokine receptor-like molecules. (PMID: 7988707) Zrihan-Licht S. … Wreschner D.H. (FEBS Lett. 1994) 3 4 23

Products for MUC1 Gene

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