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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

MTUS2 Gene

protein-coding GIFtS: 45
GCID: GC13P029599

Microtubule Associated Tumor Suppressor Candidate 2

(Previous name: KIAA0774)
(Previous symbol: KIAA0774)

Search for MTUS2
at

MalaCards

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, ¹⁰fRNAdb, ¹²H-InvDB, ¹³NCBI, ¹⁴NONCODE, and/or ¹⁵RNAdb)
About This Section

Aliases
Microtubule Associated Tumor Suppressor Candidate 2¹ ²		Tracking Protein Of 150 KDa² ³
KIAA0774¹ ² ³		CAZIP² ³
Cardiac Zipper Protein¹ ² ³		TIP150² ³
+TIP Of 150 KDa¹ ²		ICIS²
Microtubule Plus-End Tracking Protein TIP150² ³		Microtubule-Associated Tumor Suppressor Candidate 2²

External Ids:	HGNC: 20595¹	Entrez Gene: 23281²	Ensembl: ENSG00000132938⁷	UniProtKB: Q5JR59³

Export aliases for MTUS2 gene to outside databases

Previous GC identifers: GC13P028497 GC13P010420

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for MTUS2 Gene:

MTUS2 (microtubule associated tumor suppressor candidate 2) is a protein-coding gene. GO annotations related to this gene include microtubule binding and protein homodimerization activity. An important paralog of this gene is MTUS1.

UniProtKB/Swiss-Prot: MTUS2_HUMAN, Q5JR59

Function: Binds microtubules. Together with MAPRE1 may target the microtubule depolymerase KIF2C to the plus-end

of microtubules. May regulate the dynamics of microtubules at their growing distal tip

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000013.10 NT_024524.14 NC_018924.2

Regulatory elements:

Search SABiosciences Regulatory transcription factor binding sites for MTUS2
Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids

Search SABiosciences Chromatin IP Primers for MTUS2

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MTUS2

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 13q12.3 Ensembl cytogenetic band: 13q12.3 HGNC cytogenetic band: 13q12.3

MTUS2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MTUS2 gene location

GeneLoc information about chromosome 13 GeneLoc Exon Structure

GeneLoc location for GC13P029599: view genomic region (about GC identifiers)

Start:	29,598,748 bp from pter	End:	30,080,084 bp from pter
Size:	481,337 bases	Orientation:	plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE ¹MOPED, ²PaxDb, and ³MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: MTUS2_HUMAN, Q5JR59 (See protein sequence)

Recommended Name: Microtubule-associated tumor suppressor candidate 2

Size: 1369 amino acids; 150195 Da

Subunit: Homodimer. Interacts with KIF2C and MAPRE1; the interaction is direct and probably targets MTUS2 and

KIF2C to microtubules

Subcellular location: Cytoplasm, cytoskeleton. Note=Associated with the microtubule network at the growing distal

tip (the plus-end) of microtubules

Sequence caution: Sequence=AAI50246.1; Type=Erroneous initiation; Sequence=BAA34494.2; Type=Erroneous initiation;

Sequence=CAI39910.1; Type=Erroneous gene model prediction; Sequence=CAI39912.1; Type=Erroneous gene model

prediction; Sequence=CAI40386.1; Type=Erroneous gene model prediction; Sequence=CAI40565.1; Type=Erroneous gene

model prediction; Sequence=CAI40566.1; Type=Erroneous gene model prediction; Sequence=CAI41204.1; Type=Erroneous

gene model prediction;

Secondary accessions: A7E292 B4DF81 O94872 Q08E97 Q5JQR3 Q8N5E2

Alternative splicing: 3 isoforms: Q5JR59-2 Q5JR59-3 Q5JR59-4 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for MTUS2: NX_Q5JR59

Post-translational modifications:

View modification sites using PhosphoSitePlus

View neXtProt modification sites for NX_Q5JR59

MTUS2 Protein expression data from MOPED¹, PaxDb² and MAXQB³ : --

REFSEQ proteins (2 alternative transcripts):

NP_001028774.2 NP_056048.1

ENSEMBL proteins:

ENSP00000392057 ENSP00000370186 ENSP00000445403

Human Recombinant Protein Products for MTUS2:

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	Novus Biologicals MTUS2 Proteins Novus Biologicals MTUS2 Lysate
	Browse Sino Biological Recombinant Proteins Browse Sino Biological Cell Lysates
	Browse ProSpec Recombinant Proteins
	Browse Proteins at Cloud-Clone Corp.

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005813	colocalizes with centrosome	IDA	19543227
GO:0005881	colocalizes with cytoplasmic microtubule	IDA	19543227

MTUS2 for ontologies About GeneDecksing

MTUS2 Antibody Products:

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	Novus Biologicals MTUS2 Antibodies
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	ThermoFisher Antibodies for MTUS2
	LSBio Antibodies in human, mouse, rat for MTUS2

Assay Products for MTUS2:

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	GenScript Custom Assay Services for MTUS2
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	Browse ELISAs at Cloud-Clone Corp. Browse CLIAs at Cloud-Clone Corp.

(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

ProtoNet protein and cluster: Q5JR59

UniProtKB/Swiss-Prot: MTUS2_HUMAN, Q5JR59

Similarity: In the C-terminal section; belongs to the MTUS1 family

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: MTUS2_HUMAN, Q5JR59

Function: Binds microtubules. Together with MAPRE1 may target the microtubule depolymerase KIF2C to the plus-end

of microtubules. May regulate the dynamics of microtubules at their growing distal tip

Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005515	protein binding	IPI	19060904
GO:0008017	microtubule binding	IDA	19543227
GO:0042803	protein homodimerization activity	IPI	19543227

MTUS2 for ontologies About GeneDecksing

Animal Models:

inGenious Targeting Laboratory - Custom generated mouse model solutions for MTUS2

inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for MTUS2

genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for MTUS2

genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for MTUS2

miRNA Products:		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MTUS2
		8/54 QIAGEN miScript miRNA Assays for microRNAs that regulate MTUS2 (see all 54):
		hsa-miR-3678-3p hsa-miR-579 hsa-miR-488 hsa-miR-138-2* hsa-miR-507 hsa-miR-1184 hsa-miR-649 hsa-miR-525-3p

		SwitchGear 3'UTR luciferase reporter plasmid: MTUS2 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
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		OriGene clones in human, mouse for MTUS2 (see all 11) OriGene ORF clones in mouse, rat for MTUS2 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 2): MTUS2 (NM_001033602)
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Cell Line Products:		GenScript Custom overexpressing Cell Line Services for MTUS2
		Search LifeMap BioReagents cell lines for MTUS2

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MTUS2

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for MTUS2

5/25 Interacting proteins for MTUS2 (Q5JR59^{2, 3}) via UniProtKB, MINT, STRING, and/or I2D (see all 25)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
MAPRE1	Q15691²^,³	MINT-7256299 MINT-7256149 MINT-7256258 MINT-7256350 MINT-7256110 MINT-7256165 MINT-7256121 I2D: score=1
KIF2C	Q99661²^,³	MINT-7256299 MINT-7256258 MINT-7256235 MINT-7256361 MINT-7256216 MINT-7256202 I2D: score=1
PLK4	O00444²^,³	MINT-67204 I2D: score=5
ZNF655	Q8N720²^,³	MINT-67594 I2D: score=5
C1orf216	Q8TAB5²^,³	MINT-67819 I2D: score=4

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for MTUS2

Search CenterWatch for drugs/clinical trials and news about MTUS2

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for MTUS2 gene (2 alternative transcripts):

NM_001033602.2 NM_015233.5

Unigene Cluster for MTUS2:

Microtubule associated tumor suppressor candidate 2

Hs.22287 [show with all ESTs]

Unigene Representative Sequence: NM_001033602

6 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000431530(uc001usl.4 uc010tdq.2) ENST00000255289 ENST00000380808(uc001usm.4 uc010aau.3)

ENST00000400542 ENST00000467990 ENST00000542829

miRNA Products:		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MTUS2
		8/54 QIAGEN miScript miRNA Assays for microRNAs that regulate MTUS2 (see all 54):
		hsa-miR-3678-3p hsa-miR-579 hsa-miR-488 hsa-miR-138-2* hsa-miR-507 hsa-miR-1184 hsa-miR-649 hsa-miR-525-3p

		SwitchGear 3'UTR luciferase reporter plasmid: MTUS2 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
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		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MTUS2

Clone Products:		OriGene clones in human, mouse for MTUS2 (see all 11) OriGene ORF clones in mouse, rat for MTUS2 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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		DNA2.0 Custom Codon Optimized Gene Synthesis Service for MTUS2
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MTUS2
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		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MTUS2
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MTUS2

Additional mRNA sequence:

AB018317.2 AK293970.1 AK301633.1 AK302516.1 BC032481.1 BC119654.1 BC119655.1 BC129985.1

BC150245.1

6 DOTS entries:

DT.100743967 DT.209340 DT.311611 DT.120783141 DT.100658767 DT.91814423

24/30 AceView cDNA sequences (see all 30):

AB018317 CB151991 BC032481 T26932 BF512653 CF552274 BI838225 BX101662

AJ709151 AI818409 BM906724 BU788127 CB153757 AL702629 T26418 AA021163

AA962508 BG218308 R17729 R17357 BE671488 AA443334 H04911 AA248815

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

MTUS2 expression in normal human tissues (normalized intensities) MTUS2 embryonic expression: see
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>^2/3
CGAP TAG: CTGGGACAAG

About this image

MTUS2 expression in embryonic tissues and stem cells About this table

Data from LifeMap, the Embryonic Development and Stem Cells Database

5/9 selected tissues (see all 9) fully expand


Brain (Nervous System) fully expand to see all 11 entries
Epithalamus
brain/midbrain/lateral wall

Neural Tube (Nervous System) fully expand to see all 7 entries
Metencephalon
spinal cord/lateral wall

Heart (Cardiovascular System) fully expand to see all 6 entries
Left Ventricle
heart/ventricle

Peripheral Nervous System (Nervous System) fully expand to see all 2 entries
autonomic/nerve plexus/hypogastric plexus

Bone (Muscoskeletal System) fully expand to see all 2 entries
TGFbeta3+BMP7-induced chondrocytes

Genevestigator expression for MTUS2

SOURCE GeneReport for Unigene cluster: Hs.22287

UniProtKB/Swiss-Prot: MTUS2_HUMAN, Q5JR59

Tissue specificity: Detected in embryonic stem cells differentiating to cardiomyocytes

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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MTUS2

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MTUS2

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for MTUS2 gene from 5/10 species (see all 10) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Mtus2^{1 , 5}	microtubule associated tumor suppressor candidate 2^{1, 5}	75.91(n)¹ 71.24(a)¹		5 (87.82 cM)⁵ 77521¹ NM_029920.7¹ NP_084196.4¹ 147957320⁵
chicken (Gallus gallus)	Aves	MTUS2¹	microtubule associated tumor suppressor candidate 2	61.84(n) 51.22(a)		418923 XM_417117.2 XP_417117.2
lizard (Anolis carolinensis)	Reptilia	MTUS2⁶	Uncharacterized protein	72(a)	1 ↔ 1	3(185057937-185085564)
tropical clawed frog (Xenopus tropicalis)	Amphibia	Str.9204²	Transcribed sequence with weak similarity to protein more	75.11(n)		BX684473.1
zebrafish (Danio rerio)	Actinopterygii	MTUS2 (2 of 2)⁶ mtus2⁶	microtubule associated tumor suppressor candidate ... microtubule associated tumor suppressor candidate ...	53(a) 28(a)	1 ↔ many 1 ↔ many	15(3319595-3331916) 10(24995231-25052835)

ENSEMBL Gene Tree for MTUS2 (if available)
TreeFam Gene Tree for MTUS2 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for MTUS2 gene

MTUS1² CCDC69²

1 SIMAP similar gene for MTUS2 using alignment to 2 protein entries: MTUS2_HUMAN (see all proteins):

CCDC69

MTUS2 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, ⁴UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 13 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
VAR_058831⁴		--	--	see VAR_058831	2	L Q	mis⁴		0	--	--	--	--
rs59916653^1,2	C	--	10460457(+)	`TTTTT-/TTTT /TTTTTTGACAG`	1	--	int¹		1		NA	2
rs111848236^1,2	C	--	10915260(+)	`TGAGC-/CCTT CCTTC`	1	--	int¹		1		CSA	2
rs180926646^1,2		--	29596752(+)	`GTGCAC/TGTGTG`	1	--	us2k¹		0	--	--	--	--
rs115735523^1,2	F	--	29596790(+)	`AAAGTG/ATGGAA`	1	--	us2k¹		1		WA	118
rs183856282^1,2		--	29596811(+)	`CTCCAC/TTGGGG`	1	--	us2k¹		0	--	--	--	--
rs111736906^1,2	C,F	--	29596827(+)	`GGTGAC/TGGGGC`	1	--	us2k¹		2		CSA WA	120
rs188579575^1,2		--	29596888(+)	`ACTCAC/TAATAG`	1	--	us2k¹		0	--	--	--	--
rs140357575^1,2	C	--	29596989(+)	`AACTCC/TTTGGG`	1	--	us2k¹		0	--	--	--	--
rs145437446^1,2		--	29597007(+)	`ATAACC/GCTGAT`	1	--	us2k¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for MTUS2 (29598748 - 29848748 bp, first 250kb of MTUS2)

Structural Variations
Database of Genomic Variants (DGV) 10/48 variations for MTUS2 (see all 48): About this table

Variant ID	Type	Subtype	PubMed ID
esv2747206	CNV	Deletion	23290073
esv4893	CNV	Deletion	18987735
esv2747205	CNV	Deletion	23290073
esv2028726	CNV	Deletion	18987734
esv2747199	CNV	Deletion	23290073
esv992274	CNV	Deletion	20482838
esv2747209	CNV	Deletion	23290073
esv1626402	CNV	Deletion	17803354
esv5230	CNV	Deletion	18987735
esv2747207	CNV	Deletion	23290073

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MTUS2

DNA2.0 Custom Variant and Variant Library Synthesis for MTUS2

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

MTUS2 for disorders About MalaCards

MTUS2 for disorders About GeneDecksing

Genetic Association Database (GAD): MTUS2
Human Genome Epidemiology (HuGE) Navigator: MTUS2 (1 document)

Export disorders for MTUS2 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for MTUS2 gene, integrated from 9 sources (see all 20):
(articles sorted by number of sources associating them with MTUS2)

Utopia: connect your pdf to the dynamic
world of online information

TIP150 interacts with and targets MCAK at the microtubule plus ends. (PubMed id 19543227)^{1, 2, 3} Jiang K....Yao X. (2009)
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)^{1, 4} Rose J.E....Uhl G.R. (2010)
CAZIP, a novel protein expressed in the developing heart and nervous system. (PubMed id 19806667)^{1, 2} Du Puy L.... Passier R. (2009)
Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 9872452)^{1, 2} Nagase T.... Ohara O. (1998)
Regulation of a dynamic interaction between two microt ubule-binding proteins, EB1 and TIP150, by the mitotic p300/CBP-associated facto r (PCAF) orchestrates kinetochore microtubule plasticity and chromosome stabilit y during mitosis. (PubMed id 23595990)¹ Ward T....Yao X. (2013)
Intersectin (ITSN) family of scaffolds function as mol ecular hubs in protein interaction networks. (PubMed id 22558309)¹ Wong K.A....O'Bryan J.P. (2012)
Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PubMed id 23251661)¹ Comuzzie A.G....Butte N.F. (2012)
A genome-wide association study of caffeine-related sl eep disturbance: confirmation of a role for a common variant in the adenosine re ceptor. (PubMed id 22754043)¹ Byrne E.M....Martin N.G. (2012)
Germline genetic variation in an organic anion transp orter polypeptide associated with methotrexate pharmacokinetics and clinical ef fects. (PubMed id 19901119)¹ TreviA+o L.R....Relling M.V. (2009)
An empirical framework for binary interactome mapping . (PubMed id 19060904)¹ Venkatesan K....Vidal M. (2009)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 23281	HGNC: 20595	AceView: KIAA0774	Ensembl:ENSG00000132938	euGenes: HUgn23281
ECgene: MTUS2	H-InvDB: MTUS2

(According to HUGE)
About This Section

HUGE: KIAA0774

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for MTUS2	Pharmacogenomics, SNPs, Pathways

Intellectual Property for MTUS2 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for MTUS2 gene:
Search GeneIP for patents involving MTUS2

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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MTUS2 Gene

Microtubule Associated Tumor Suppressor Candidate 2

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MTUS2 Gene

Microtubule Associated Tumor Suppressor Candidate 2

Aliasesfor MTUS2 gene

Summariesfor MTUS2 gene

Genomic Viewsfor MTUS2 gene

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Protein Domains /Familiesfor MTUS2 gene

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Specialized Databases showing MTUS2 gene

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Aliases
for MTUS2 gene

Summaries
for MTUS2 gene

Genomic Views
for MTUS2 gene

Proteins
for MTUS2 gene

Protein Domains /
Families
for MTUS2 gene

Function
for MTUS2 gene

Pathways & Interactions
for MTUS2 gene

Drugs & Compounds
for MTUS2 gene

Transcripts
for MTUS2 gene

Expression
for MTUS2 gene

Orthologs
for MTUS2 gene

Paralogs
for MTUS2 gene

Genomic Variants
for MTUS2 gene

Disorders / Diseases
for MTUS2 gene

Publications
for MTUS2 gene

Intellectual Property
for MTUS2 gene

Products
for MTUS2 gene