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Aliases for MTURN Gene

Aliases for MTURN Gene

  • Maturin, Neural Progenitor Differentiation Regulator Homolog (Xenopus) 2 3 5
  • Maturin Neural Progenitor Differentiation Regulator Protein Homolog 3 4
  • Protein Ells1 3 4
  • C7orf41 3 4
  • Chromosome 7 Open Reading Frame 41 2
  • UPF0452 Protein C7orf41 3
  • Ells1 3

External Ids for MTURN Gene

Previous HGNC Symbols for MTURN Gene

  • C7orf41

Previous GeneCards Identifiers for MTURN Gene

  • GC07P030174

Summaries for MTURN Gene

GeneCards Summary for MTURN Gene

MTURN (Maturin, Neural Progenitor Differentiation Regulator Homolog (Xenopus)) is a Protein Coding gene.

UniProtKB/Swiss-Prot for MTURN Gene

  • May be involved in early neuronal development.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MTURN Gene

Genomics for MTURN Gene

Regulatory Elements for MTURN Gene

Enhancers for MTURN Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around MTURN on UCSC Golden Path with GeneCards custom track

Promoters for MTURN Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around MTURN on UCSC Golden Path with GeneCards custom track

Genomic Location for MTURN Gene

30,134,810 bp from pter
30,162,765 bp from pter
27,956 bases
Plus strand

Genomic View for MTURN Gene

Genes around MTURN on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MTURN Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MTURN Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MTURN Gene

Proteins for MTURN Gene

  • Protein details for MTURN Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein Accession:
    Secondary Accessions:
    • B8ZZW9
    • Q8N791
    • Q8N8M4
    • Q8NEX2

    Protein attributes for MTURN Gene

    131 amino acids
    Molecular mass:
    14925 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for MTURN Gene


neXtProt entry for MTURN Gene

Proteomics data for MTURN Gene at MOPED

Post-translational modifications for MTURN Gene

  • Ubiquitination at Lys 80 and Lys 88
  • Modification sites at PhosphoSitePlus

Other Protein References for MTURN Gene

No data available for DME Specific Peptides for MTURN Gene

Domains & Families for MTURN Gene

Protein Domains for MTURN Gene


Suggested Antigen Peptide Sequences for MTURN Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the MTURN family.
  • Belongs to the MTURN family.
genes like me logo Genes that share domains with MTURN: view

No data available for Gene Families for MTURN Gene

Function for MTURN Gene

Molecular function for MTURN Gene

UniProtKB/Swiss-Prot Function:
May be involved in early neuronal development.
genes like me logo Genes that share phenotypes with MTURN: view

Animal Model Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MTURN Gene

Localization for MTURN Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MTURN Gene

Pathways & Interactions for MTURN Gene

SuperPathways for MTURN Gene

No Data Available

Interacting Proteins for MTURN Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
Selected Interacting proteins: ENSP00000324204 for MTURN Gene via STRING

Gene Ontology (GO) - Biological Process for MTURN Gene


No data available for Pathways by source and SIGNOR curated interactions for MTURN Gene

Drugs & Compounds for MTURN Gene

No Compound Related Data Available

Transcripts for MTURN Gene

Alternative Splicing Database (ASD) splice patterns (SP) for MTURN Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b · 5c · 5d · 5e ^ 6
SP1: - - - - - -
SP4: - -
SP5: - - - -
SP6: -

Relevant External Links for MTURN Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MTURN Gene

mRNA expression in normal human tissues for MTURN Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for MTURN Gene

This gene is overexpressed in Brain - Spinal cord (cervical c-1) (x10.7), Brain - Substantia nigra (x6.4), Brain - Amygdala (x5.1), Brain - Hippocampus (x5.1), and Brain - Putamen (basal ganglia) (x4.3).

Protein differential expression in normal tissues from HIPED for MTURN Gene

This gene is overexpressed in Spinal cord (28.7), Nasopharynx (6.5), and Peripheral blood mononuclear cells (6.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for MTURN Gene

genes like me logo Genes that share expression patterns with MTURN: view

Primer Products

No data available for mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MTURN Gene

Orthologs for MTURN Gene

This gene was present in the common ancestor of chordates.

Orthologs for MTURN Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia MTURN 35
  • 95.67 (n)
  • 100 (a)
C4H7orf41 36
  • 100 (a)
(Pan troglodytes)
Mammalia MTURN 35
  • 99.49 (n)
  • 100 (a)
  • 100 (a)
(Rattus norvegicus)
Mammalia Mturn 35
  • 90.84 (n)
  • 96.95 (a)
(Canis familiaris)
Mammalia MTURN 36
  • 96 (a)
(Monodelphis domestica)
Mammalia MTURN 36
  • 96 (a)
(Ornithorhynchus anatinus)
Mammalia MTURN 36
  • 46 (a)
(Gallus gallus)
Aves MTURN 35
  • 82.7 (n)
  • 85.5 (a)
gga-mir-1723 36
  • 85 (a)
(Anolis carolinensis)
Reptilia MTURN 36
  • 92 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia mturn 35
  • 83.46 (n)
  • 92.37 (a)
Str.11166 35
African clawed frog
(Xenopus laevis)
Amphibia MGC53931 35
(Danio rerio)
Actinopterygii mturn 35
  • 75.9 (n)
  • 78.46 (a)
mturn 36
  • 75 (a)
Species with no ortholog for MTURN:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MTURN Gene

Gene Tree for MTURN (if available)
Gene Tree for MTURN (if available)

Paralogs for MTURN Gene

No data available for Paralogs for MTURN Gene

Variants for MTURN Gene

Sequence variations from dbSNP and Humsavar for MTURN Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs887883 -- 30,139,778(+) TCTCT(A/G)TCTCG intron-variant
rs957868 -- 30,153,111(+) CTTTT(A/C/T)GGTAT intron-variant
rs997349 -- 30,142,828(+) AGTCA(A/G)TACTT intron-variant
rs1003696 -- 30,141,471(+) GTGGA(C/T)TGTGG intron-variant
rs1054366 -- 30,159,778(+) TGTGT(A/G)CACAT utr-variant-3-prime

Variation tolerance for MTURN Gene

Residual Variation Intolerance Score: 58.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.20; 4.48% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for MTURN Gene

Disorders for MTURN Gene

Relevant External Links for MTURN

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MTURN Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MTURN Gene

Publications for MTURN Gene

  1. Maturin is a novel protein required for differentiation during primary neurogenesis. (PMID: 24095902) Martinez-De Luna R.I. … Zuber M.E. (Dev. Biol. 2013) 2 3 67
  2. Novel function of the chromosome 7 open reading frame 41 gene to promote leukemic megakaryocyte differentiation by modulating TPA-induced signaling. (PMID: 24681962) Sun X. … Huang Z. (Blood Cancer J 2014) 3
  3. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) OlA!h J. … OvA!di J. (J. Biol. Chem. 2011) 3
  4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3
  5. Ubiquitin-mediated proteolysis of HuR by heat shock. (PMID: 19322201) Abdelmohsen K. … Gorospe M. (EMBO J. 2009) 3

Products for MTURN Gene

Sources for MTURN Gene