MTSS1L Gene
protein-coding GIFtS : 40
GCID: GC16 M070695
metastasis suppressor 1-like
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Aliasesfor MTSS1L gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases Metastasis Suppressor 1-Like 1 2 ABBA-11 2 3 Actin-Bundling With BAIAP2 Homology Protein 12 3 LOC921541 Actin-Bundling Protein With BAIAP2 Homology2 MTSS1-Like Protein2
Export aliases for MTSS1L gene to outside databases Previous GC identifers: GC16M069254 GC16M056526
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Summariesfor MTSS1L gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section UniProtKB/Swiss-Prot: MTSSL_HUMAN, Q765P7 Function : May function in actin bundling
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Genomic Viewsfor MTSS1L gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,
and/or miRBase ,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000016.9 NC_018927.1 NT_010498.15 Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the MTSS1L gene promoter: HEN1 USF1 Pax-5 Hand1 USF-1:USF-2 Tal-1beta Gfi-1 E47 Other transcription factors Search SABiosciences Chromatin IP Primers for MTSS1L Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human , mouse , rat MTSS1L
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 16q22.1 Ensembl cytogenetic band: 16q22.1 HGNC cytogenetic band: 16q22.1 MTSS1L Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc information about chromosome 16 GeneLoc Exon Structure
GeneLoc location for GC16M070695: view genomic region
(about GC identifiers )
Start:
70,695,107 bp from pter
End:
70,719,969 bp from pter
Size:
24,863 bases
Orientation:
minus strand
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Proteinsfor MTSS1L gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
Biochemical Assays by
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB/Swiss-Prot: MTSSL_HUMAN, Q765P7 (See
protein sequence )Recommended Name: MTSS1-like protein Size : 747 amino acids; 79929 Da
Secondary accessions : A6NJI7 Q9BUA8Alternative splicing : 2 isoforms : Q765P7-1 Q765P7-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for MTSS1L: NX_Q765P7 Post-translational modifications:
View modification sites using PhosphoSitePlus 2 View neXtProt modification sites for NX_Q765P7 MTSS1L Protein expression data from MOPED and PaxDb : About this image
REFSEQ proteins: NP_612392.1 ENSEMBL proteins: ENSP00000341171 ENSP00000455480 ENSP00000459654 Human Recombinant Protein Products: MTSS1L Antibody Products: Assay Products for MTSS1L:
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Protein
Domains / Familiesfor MTSS1L gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section
MTSS1L for domains About GeneDecksing 1 InterPro domain/family :
Graphical View of Domain Structure for InterPro Entry Q765P7 ProtoNet protein and cluster: Q765P7
UniProtKB/Swiss-Prot: MTSSL_HUMAN, Q765P7 Similarity : Belongs to the MTSS1 familySimilarity : Contains 1 IMD (IRSp53/MIM homology) domainSimilarity : Contains 1 WH2 domain
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Functionfor MTSS1L gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences ,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section Function Summary: UniProtKB/Swiss-Prot: MTSSL_HUMAN, Q765P7 Function : May function in actin bundling
Clone Products: Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for MTSS1L (see all 2 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for MTSS1LOriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: MTSS1L (NM_138383 ) Browse Sino Biological Human cDNA Clones DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MTSS1L Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat MTSS1L
In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MTSS1L
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view) : About this table
MTSS1L for ontologies About GeneDecksing
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Pathways & Interactionsfor MTSS1L gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Interactions: Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MTSS1L Gene Ontology (GO): 2 biological process terms (GO ID links to tree view) : About this table
GO ID Qualified GO term Evidence PubMed IDs GO:0007165 signal transduction
IEA -- GO:0046847 filopodium assembly
IEA --
MTSS1L for ontologies About GeneDecksing
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Drugs & Compoundsfor MTSS1L gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section Browse Tocris compounds for MTSS1L Search CenterWatch for drugs/clinical trials and news about MTSS1L / MTSSL
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Transcriptsfor MTSS1L gene (Secondary structures according to
fRNAdb ,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
microRNA from QIAGEN ,
Tagged/untagged cDNA clones from
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section REFSEQ mRNAs for MTSS1L gene: NM_138383.2 Unigene Cluster for MTSS1L:
Metastasis suppressor 1-like Hs.432387 [show with all ESTs ] Unigene Representative Sequence: NM_138383 3 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000338779 (uc002ezk.1 uc002ezj.3 ) ENST00000562883 ENST00000576338 Clone Products: OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for MTSS1L (see all 2 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for MTSS1LOriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: MTSS1L (NM_138383 ) DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MTSS1L Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat MTSS1L
Additional cDNA sequence: AB115770.1 BC002770.1 BC011452.2 BC024752.1 BC025271.1
9 DOTS entries : DT.75194149 DT.97849342
DT.102830701 DT.100777725 DT.91746397 DT.91746395 DT.100777723 DT.95116088 DT.95206041 24/182 AceView cDNA sequences (see all 182 ):
BM669502 CB159940 AI784033 BU739115 BF197698 BQ018188 BF924396 CF541198 BM668517 BU859607 T32140 BX283517 BM695350 AA338945 BQ961872 BM722827 BM676669 CR590913 AB115770 BM714270 N74883 BM678314 BQ008633 BU741772 GeneLoc Exon Structure
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Expression for MTSS1L gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,
PCR Arrays from
SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section MTSS1L expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: ACAGAGGGGC
About this image MTSS1L expression in embryonic tissues and stem cells Expression by the Database of Embryonic development, Stem cell research, and
Regenerative medicine About this table See MTSS1L Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for MTSS1L SOURCE GeneReport for Unigene cluster: Hs.432387 SABiosciences Custom PCR Arrays for MTSS1L Primer Products: OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for MTSS1LBrowse OriGene validated miRNA SYBR primer pairs SABiosciences RT2 qPCR Primer Assay in human , mouse / rat MTSS1L QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat MTSS1L QIAGEN QuantiFast Probe-based Assays in human , mouse , rat MTSS1L In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MTSS1L
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Orthologsfor MTSS1L gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section
This gene was present in the common ancestor of animals.
Orthologs for MTSS1L gene from 6/19 species (see all 19 ) About this table
ENSEMBL Gene Tree for MTSS1L (if available)TreeFam Gene Tree for MTSS1L (if available)
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Paralogsfor MTSS1L gene (Paralogs according to
1 HomoloGene , 2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section Paralogs for MTSS1L gene MTSS1 2 1 SIMAP similar gene for MTSS1L using alignment to 4 protein entries: MTSSL_HUMAN (see all proteins ):MTSS1
MTSS1L for paralogs About GeneDecksing
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Genomic Variantsfor MTSS1L gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section
Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical significance Chr 16 pos Sequence # AA Chg Type More # Allele freq Pop Total sample More
HapMap Linkage Disequilibrium report for MTSS1L (70695107 - 70719969 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 3 variations for MTSS1L 3 CNVs : 49742 77401 49741
SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing MTSS1L
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Disorders
/ Diseasesfor MTSS1L gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section --
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Publicationsfor MTSS1L gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for MTSS1L gene integrated from 9 sources : (articles sorted by number of sources associating them with MTSS1L) Utopia : connect your pdf to the dynamic world of online information
A novel actin bundling/filopodium-forming domain conserved in insulin receptor tyrosine kinase substrate p53 and missing in metastasis protein. (PubMed id 14752106) 1 , 2 Yamagishi A.... Mochizuki N. (2004) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932) 1 , 3 Strausberg R.L....Marra M.A. (2002) Abba promotes PDGF-mediated membrane ruffling through activation of the small GTPase Rac1. (PubMed id 20875796) 1 Zheng D....Zhan X. (2010) Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231) 2 Olsen J.V....Mann M. (2010) Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332) 2 Mayya V.... Han D.K. (2009) Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis. (PubMed id 18220336) 2 Cantin G.T....Yates J.R. III (2008) A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648) 2 Dephoure N.... Gygi S.P. (2008) The sequence and analysis of duplication-rich human chromosome 16. (PubMed id 15616553) 2 Martin J.... Pennacchio L.A. (2004) The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334) 2 Gerhard D.S....Malek J. (2004)
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External Searches for MTSS1L gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing MTSS1L gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
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Other Databases showing MTSS1L gene
(According to HUGE )
About This Section --
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Specialized Databases showing MTSS1L gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description
PharmGKB entry for MTSS1L Pharmacogenomics, SNPs, Pathways
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About This Section Patent Information for MTSS1L gene: Search GeneIP for patents involving MTSS1L GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor MTSS1L gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript and LifeMap BioReagents , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences ), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
Browse OriGene Antibodies OriGene shRNA RFP for MTSS1L OriGene 29mer shRNA kits in GFP-retroviral vector in human , mouse , rat for MTSS1L OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for MTSS1L Browse OriGene Protein Over-expression Lysates Browse OriGene Fluorogenic Cell Assay Kits OriGene siRNA for MTSS1L Browse 3'-UTR reporter clones for miRNA target validation OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for MTSS1L OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for MTSS1L Browse OriGene GFP tagged cDNA clones in CMV expression vector Browse OriGene MicroRNA Expression Plasmids Browse OriGene basic RS shRNAs Browse OriGene validated miRNA SYBR primer pairs Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling OriGene Custom Antibody Services for MTSS1L OriGene Custom Protein Services for MTSS1L OriGene Custom Immunoassay Development
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MTSS1L QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing MTSS1L QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human , mouse , rat MTSS1L QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human , mouse , rat MTSS1L QIAGEN QuantiFast Probe-based Assays in human , mouse , rat MTSS1L QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat MTSS1L
Search Tocris compounds for MTSS1L
MTSS1L Proteins, Antibodies, CLIAs, and ELISAs
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MTSS1L
Search ThermoFisher Antibodies for MTSS1L
Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat MTSS1L
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Proteins for MTSS1L
Publications for MTSS1L
Search Box for MTSS1L
Summaries for MTSS1L
Transcripts for MTSS1L
Variants for MTSS1L
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