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Aliases for MTRNR2L9 Gene

Aliases for MTRNR2L9 Gene

  • MT-RNR2-Like 9 2 3
  • MT-RNR2-Like 9 (Pseudogene) 2 3
  • HN9 3 4
  • Humanin-Like Protein 9 3
  • MT-RNR2-Like Protein 9 4
  • Humanin-Like 9 3
  • MTRNR2-Like 9 3

External Ids for MTRNR2L9 Gene

Previous GeneCards Identifiers for MTRNR2L9 Gene

  • GC06U901943
  • GC06P059449
  • GC06P062284

Summaries for MTRNR2L9 Gene

GeneCards Summary for MTRNR2L9 Gene

MTRNR2L9 (MT-RNR2-Like 9) is a Protein Coding gene.

UniProtKB/Swiss-Prot for MTRNR2L9 Gene

  • Plays a role as a neuroprotective and antiapoptotic factor.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MTRNR2L9 Gene

Genomics for MTRNR2L9 Gene

Genomic Location for MTRNR2L9 Gene

Start:
61,574,103 bp from pter
End:
61,574,629 bp from pter
Size:
527 bases
Orientation:
Plus strand

Genomic View for MTRNR2L9 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MTRNR2L9 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MTRNR2L9 Gene

No data available for Regulatory Elements for MTRNR2L9 Gene

Proteins for MTRNR2L9 Gene

  • Protein details for MTRNR2L9 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P0CJ76-HMN9_HUMAN
    Recommended name:
    Humanin-like 9
    Protein Accession:
    P0CJ76
    Secondary Accessions:

    Protein attributes for MTRNR2L9 Gene

    Size:
    24 amino acids
    Molecular mass:
    2694 Da
    Quaternary structure:
    No Data Available

neXtProt entry for MTRNR2L9 Gene

Proteomics data for MTRNR2L9 Gene at MOPED

Post-translational modifications for MTRNR2L9 Gene

No Post-translational modifications

Other Protein References for MTRNR2L9 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for MTRNR2L9 Gene

Domains for MTRNR2L9 Gene

Protein Domains for MTRNR2L9 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for MTRNR2L9 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

P0CJ76

UniProtKB/Swiss-Prot:

HMN9_HUMAN :
  • P0CJ76
Family:
  • Belongs to the humanin family.
genes like me logo Genes that share domains with MTRNR2L9: view

No data available for Gene Families for MTRNR2L9 Gene

Function for MTRNR2L9 Gene

Molecular function for MTRNR2L9 Gene

UniProtKB/Swiss-Prot Function: Plays a role as a neuroprotective and antiapoptotic factor.
UniProtKB/Swiss-Prot Induction: Down-regulated 6 hours following staurosporine (STS) treatment and up-regulated 24 hours following STS treatment. Down-regulated 6 hours following beta-carotene treatment, returning to its basal level 24 hours following beta-carotene treatment.

Animal Model Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MTRNR2L9 Gene

Localization for MTRNR2L9 Gene

Subcellular locations from UniProtKB/Swiss-Prot for MTRNR2L9 Gene

Secreted. Cytoplasm.

Gene Ontology (GO) - Cellular Components for MTRNR2L9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IEA --
GO:0005737 cytoplasm IEA --
genes like me logo Genes that share ontologies with MTRNR2L9: view

No data available for Subcellular locations from COMPARTMENTS for MTRNR2L9 Gene

Pathways for MTRNR2L9 Gene

SuperPathways for MTRNR2L9 Gene

No Data Available

Interacting Proteins for MTRNR2L9 Gene

Gene Ontology (GO) - Biological Process for MTRNR2L9 Gene

None

No data available for Pathways by source for MTRNR2L9 Gene

Transcripts for MTRNR2L9 Gene

mRNA/cDNA for MTRNR2L9 Gene

(1) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for MTRNR2L9

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MTRNR2L9 Gene

No ASD Table

Relevant External Links for MTRNR2L9 Gene

GeneLoc Exon Structure for
MTRNR2L9
ECgene alternative splicing isoforms for
MTRNR2L9

Expression for MTRNR2L9 Gene

mRNA expression in normal human tissues for MTRNR2L9 Gene

mRNA differential expression in normal tissues according to GTEx for MTRNR2L9 Gene

This gene is overexpressed in Brain - Amygdala (7.4), Brain - Frontal Cortex (BA9) (5.6), Brain - Putamen (basal ganglia) (5.2), Brain - Caudate (basal ganglia) (4.4), Brain - Anterior cingulate cortex (BA24) (4.3), and Brain - Substantia nigra (4.2).

mRNA Expression by UniProt/SwissProt for MTRNR2L9 Gene

P0CJ76-HMN9_HUMAN
Tissue specificity: Highly expressed in the kidney, heart muscle and testis.
genes like me logo Genes that share expressions with MTRNR2L9: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and Protein expression for MTRNR2L9 Gene

Orthologs for MTRNR2L9 Gene

Evolution for MTRNR2L9 Gene

ENSEMBL:
Gene Tree for MTRNR2L9 (if available)
TreeFam:
Gene Tree for MTRNR2L9 (if available)

No data available for Orthologs for MTRNR2L9 Gene

Paralogs for MTRNR2L9 Gene

Selected SIMAP similar genes for MTRNR2L9 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with MTRNR2L9: view

No data available for Paralogs for MTRNR2L9 Gene

Variants for MTRNR2L9 Gene

Sequence variations from dbSNP and Humsavar for MTRNR2L9 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type MAF
rs2344448 -- 61,574,140(-) TCCTT(A/G)TGGGC utr-variant-5-prime
rs2344449 -- 61,573,808(-) ctttt(A/T)ctttt upstream-variant-2KB
rs2344450 -- 61,573,548(-) cctcc(A/G)aaagt upstream-variant-2KB
rs3056644 -- 61,573,899(-) aacta(-/TA)gttag upstream-variant-2KB
rs3056645 -- 61,573,898(-) actag(-/AGCCTT/CC/CCT)ttagt upstream-variant-2KB

Relevant External Links for MTRNR2L9 Gene

HapMap Linkage Disequilibrium report
MTRNR2L9

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for MTRNR2L9 Gene

Disorders for MTRNR2L9 Gene

No disorders were found for MTRNR2L9 Gene.

No data available for UniProtKB/Swiss-Prot for MTRNR2L9 Gene

Publications for MTRNR2L9 Gene

  1. Evidence for potential functionality of nuclearly-encoded humanin isoforms. (PMID: 19477263) Bodzioch M. … Dembinska-Kiec A. (Genomics 2009) 2 3 4
  2. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall A.J. … Beck S. (Nature 2003) 3 4
  3. A rescue factor abolishing neuronal cell death by a wide spectrum of familial Alzheimer's disease genes and Abeta. (PMID: 11371646) Hashimoto Y. … Nashimoto I. (Proc. Natl. Acad. Sci. U.S.A. 2001) 3
  4. Evidence for in vivo production of Humanin peptide, a neuroprotective factor against Alzheimer's disease-related insults. (PMID: 12009529) Tajima H. … Nishimoto I. (Neurosci. Lett. 2002) 3
  5. Humanin peptide suppresses apoptosis by interfering with Bax activation. (PMID: 12732850) Guo B. … Reed J.C. (Nature 2003) 3

Products for MTRNR2L9 Gene

Sources for MTRNR2L9 Gene

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