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Aliases for MTRNR2L3 Gene

Aliases for MTRNR2L3 Gene

  • MT-RNR2-Like 3 2 3
  • Humanin-Like 3 2 3
  • HN3 3 4
  • Humanin-Like Protein 3 3
  • MT-RNR2-Like Protein 3 4
  • MTRNR2-Like 3 3

External Ids for MTRNR2L3 Gene

Previous GeneCards Identifiers for MTRNR2L3 Gene

  • GC20U900575
  • GC20M055937
  • GC20M055938
  • GC20M055939
  • GC20M055941
  • GC20M055944
  • GC20M055947
  • GC20M055952
  • GC20M055956

Summaries for MTRNR2L3 Gene

GeneCards Summary for MTRNR2L3 Gene

MTRNR2L3 (MT-RNR2-Like 3) is a Protein Coding gene.

UniProtKB/Swiss-Prot for MTRNR2L3 Gene

  • Plays a role as a neuroprotective and antiapoptotic factor.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MTRNR2L3 Gene

Genomics for MTRNR2L3 Gene

Genomic Location for MTRNR2L3 Gene

57,358,440 bp from pter
57,359,980 bp from pter
1,541 bases
Minus strand

Genomic View for MTRNR2L3 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MTRNR2L3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MTRNR2L3 Gene

No data available for Regulatory Elements for MTRNR2L3 Gene

Proteins for MTRNR2L3 Gene

  • Protein details for MTRNR2L3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Humanin-like 3
    Protein Accession:
    Secondary Accessions:

    Protein attributes for MTRNR2L3 Gene

    24 amino acids
    Molecular mass:
    2796 Da
    Quaternary structure:
    No Data Available

neXtProt entry for MTRNR2L3 Gene

Proteomics data for MTRNR2L3 Gene at MOPED

Post-translational modifications for MTRNR2L3 Gene

No Post-translational modifications

Other Protein References for MTRNR2L3 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for MTRNR2L3 Gene

Domains for MTRNR2L3 Gene

Protein Domains for MTRNR2L3 Gene


Suggested Antigen Peptide Sequences for MTRNR2L3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the humanin family.
  • Belongs to the humanin family.
genes like me logo Genes that share domains with MTRNR2L3: view

No data available for Gene Families for MTRNR2L3 Gene

Function for MTRNR2L3 Gene

Molecular function for MTRNR2L3 Gene

UniProtKB/Swiss-Prot Function:
Plays a role as a neuroprotective and antiapoptotic factor.
UniProtKB/Swiss-Prot Induction:
Down-regulated 6 hours following staurosporine (STS) treatment and up-regulated 24 hours following STS treatment. Down-regulated 6 hours following beta-carotene treatment, while it is up-regulated 24 hours following beta-carotene treatment.

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MTRNR2L3 Gene

Localization for MTRNR2L3 Gene

Subcellular locations from UniProtKB/Swiss-Prot for MTRNR2L3 Gene

Secreted. Cytoplasm.

Gene Ontology (GO) - Cellular Components for MTRNR2L3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IEA --
GO:0005737 cytoplasm IEA --
genes like me logo Genes that share ontologies with MTRNR2L3: view

No data available for Subcellular locations from COMPARTMENTS for MTRNR2L3 Gene

Pathways for MTRNR2L3 Gene

SuperPathways for MTRNR2L3 Gene

No Data Available

Interacting Proteins for MTRNR2L3 Gene

Gene Ontology (GO) - Biological Process for MTRNR2L3 Gene


No data available for Pathways by source for MTRNR2L3 Gene

Transcripts for MTRNR2L3 Gene

mRNA/cDNA for MTRNR2L3 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MTRNR2L3 Gene

No ASD Table

Relevant External Links for MTRNR2L3 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MTRNR2L3 Gene

mRNA expression in normal human tissues for MTRNR2L3 Gene

SOURCE GeneReport for Unigene cluster for MTRNR2L3 Gene Hs.727477

mRNA Expression by UniProt/SwissProt for MTRNR2L3 Gene

Tissue specificity: Highly expressed in testis. Also expressed in kidney, heart, skeletal muscles and brain.
genes like me logo Genes that share expressions with MTRNR2L3: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression and Expression partners for MTRNR2L3 Gene

Orthologs for MTRNR2L3 Gene

Evolution for MTRNR2L3 Gene

Gene Tree for MTRNR2L3 (if available)
Gene Tree for MTRNR2L3 (if available)

No data available for Orthologs for MTRNR2L3 Gene

Paralogs for MTRNR2L3 Gene

(2) SIMAP similar genes for MTRNR2L3 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with MTRNR2L3: view

No data available for Paralogs for MTRNR2L3 Gene

Variants for MTRNR2L3 Gene

Structural Variations from Database of Genomic Variants (DGV) for MTRNR2L3 Gene

Variant ID Type Subtype PubMed ID
nsv459027 CNV Loss 19166990

Relevant External Links for MTRNR2L3 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for MTRNR2L3 Gene

Disorders for MTRNR2L3 Gene

No disorders were found for MTRNR2L3 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for MTRNR2L3 Gene

Publications for MTRNR2L3 Gene

  1. Evidence for potential functionality of nuclearly-encoded humanin isoforms. (PMID: 19477263) Bodzioch M. … Dembinska-Kiec A. (Genomics 2009) 2 3 4
  2. The DNA sequence and comparative analysis of human chromosome 20. (PMID: 11780052) Deloukas P. … Rogers J. (Nature 2001) 3 4
  3. Evidence for in vivo production of Humanin peptide, a neuroprotective factor against Alzheimer's disease-related insults. (PMID: 12009529) Tajima H. … Nishimoto I. (Neurosci. Lett. 2002) 3
  4. Humanin peptide suppresses apoptosis by interfering with Bax activation. (PMID: 12732850) Guo B. … Reed J.C. (Nature 2003) 3
  5. Humanin: a novel central regulator of peripheral insulin action. (PMID: 19623253) Muzumdar R.H. … Cohen P. (PLoS ONE 2009) 3

Products for MTRNR2L3 Gene

Sources for MTRNR2L3 Gene

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