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Aliases for MTRNR2L10 Gene

Aliases for MTRNR2L10 Gene

  • MT-RNR2-Like 10 2 3
  • Humanin-Like 10 2 3
  • HN10 3 4
  • Humanin-Like Protein 10 3
  • MT-RNR2-Like Protein 10 4
  • MTRNR2-Like 10 3

External Ids for MTRNR2L10 Gene

Summaries for MTRNR2L10 Gene

GeneCards Summary for MTRNR2L10 Gene

MTRNR2L10 (MT-RNR2-Like 10) is a Protein Coding gene.

UniProtKB/Swiss-Prot for MTRNR2L10 Gene

  • Plays a role as a neuroprotective and antiapoptotic factor.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MTRNR2L10 Gene

Genomics for MTRNR2L10 Gene

Genomic Location for MTRNR2L10 Gene

Start:
55,181,391 bp from pter
End:
55,182,920 bp from pter
Size:
1,530 bases
Orientation:
Minus strand

Genomic View for MTRNR2L10 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MTRNR2L10 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MTRNR2L10 Gene

No data available for Regulatory Elements for MTRNR2L10 Gene

Proteins for MTRNR2L10 Gene

  • Protein details for MTRNR2L10 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P0CJ77-HMN10_HUMAN
    Recommended name:
    Humanin-like 10
    Protein Accession:
    P0CJ77
    Secondary Accessions:

    Protein attributes for MTRNR2L10 Gene

    Size:
    24 amino acids
    Molecular mass:
    2806 Da
    Quaternary structure:
    No Data Available

neXtProt entry for MTRNR2L10 Gene

Proteomics data for MTRNR2L10 Gene at MOPED

Post-translational modifications for MTRNR2L10 Gene

No Post-translational modifications

Other Protein References for MTRNR2L10 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for MTRNR2L10 Gene

Domains for MTRNR2L10 Gene

Protein Domains for MTRNR2L10 Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

HMN10_HUMAN
Family:
  • Belongs to the humanin family.:
    • P0CJ77
genes like me logo Genes that share domains with MTRNR2L10: view

No data available for Gene Families for MTRNR2L10 Gene

Function for MTRNR2L10 Gene

Molecular function for MTRNR2L10 Gene

UniProtKB/Swiss-Prot Function: Plays a role as a neuroprotective and antiapoptotic factor.
UniProtKB/Swiss-Prot Induction: Down-regulated 6 hours following staurosporine (STS) treatment and up-regulated 24 hours following STS treatment. Down-regulated 6 hours following beta-carotene treatment, while it is up-regulated 24 hours following beta-carotene treatment.

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MTRNR2L10 Gene

Localization for MTRNR2L10 Gene

Subcellular locations from UniProtKB/Swiss-Prot for MTRNR2L10 Gene

Secreted. Cytoplasm.

Gene Ontology (GO) - Cellular Components for MTRNR2L10 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IEA --
GO:0005737 cytoplasm IEA --
genes like me logo Genes that share ontologies with MTRNR2L10: view

Pathways for MTRNR2L10 Gene

SuperPathways for MTRNR2L10 Gene

No Data Available

Interacting Proteins for MTRNR2L10 Gene

Gene Ontology (GO) - Biological Process for MTRNR2L10 Gene

None

No data available for Pathways by source for MTRNR2L10 Gene

Transcripts for MTRNR2L10 Gene

mRNA/cDNA for MTRNR2L10 Gene

(1) REFSEQ mRNAs :
(0) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for MTRNR2L10 Gene

MT-RNR2-like 10:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for MTRNR2L10 Gene

No ASD Table

Relevant External Links for MTRNR2L10 Gene

GeneLoc Exon Structure for
MTRNR2L10
ECgene alternative splicing isoforms for
MTRNR2L10

Expression for MTRNR2L10 Gene

mRNA expression in normal human tissues for MTRNR2L10 Gene

SOURCE GeneReport for Unigene cluster for MTRNR2L10 Gene Hs.722730

mRNA Expression by UniProt/SwissProt for MTRNR2L10 Gene

P0CJ77-HMN10_HUMAN
Tissue specificity: Expressed in mature brain, thyroid gland and testis.
genes like me logo Genes that share expressions with MTRNR2L10: view

Orthologs for MTRNR2L10 Gene

Evolution for MTRNR2L10 Gene

ENSEMBL:
Gene Tree for MTRNR2L10 (if available)
TreeFam:
Gene Tree for MTRNR2L10 (if available)

No data available for Orthologs for MTRNR2L10 Gene

Paralogs for MTRNR2L10 Gene

Selected SIMAP similar genes for MTRNR2L10 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with MTRNR2L10: view

No data available for Paralogs for MTRNR2L10 Gene

Variants for MTRNR2L10 Gene

Sequence variations from dbSNP and Humsavar for MTRNR2L10 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs5960402 -- 55,181,461(+) GGAGC(A/G)AGGGC utr-variant-3-prime
rs5960403 -- 55,181,535(+) AAACC(G/T)ACCTG utr-variant-3-prime
rs10521478 -- 55,181,728(+) TTATC(A/G)GGTCA utr-variant-3-prime
rs12846023 -- 55,184,175(+) ATTTA(A/G)GACAT upstream-variant-2KB
rs12846441 -- 55,184,329(+) ATTGA(A/G)GGGTA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MTRNR2L10 Gene

Variant ID Type Subtype PubMed ID
nsv435891 CNV Deletion 17901297
esv2740175 CNV Deletion 23290073
esv2740181 CNV Deletion 23290073

Relevant External Links for MTRNR2L10 Gene

HapMap Linkage Disequilibrium report
MTRNR2L10

Disorders for MTRNR2L10 Gene

No disorders were found for MTRNR2L10 Gene.

No data available for UniProtKB/Swiss-Prot for MTRNR2L10 Gene

Publications for MTRNR2L10 Gene

  1. Evidence for potential functionality of nuclearly-encoded humanin isoforms. (PMID: 19477263) Bodzioch M. … Dembinska-Kiec A. (Genomics 2009) 2 3 4
  2. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 3 4
  3. A rescue factor abolishing neuronal cell death by a wide spectrum of familial Alzheimer's disease genes and Abeta. (PMID: 11371646) Hashimoto Y. … Nashimoto I. (Proc. Natl. Acad. Sci. U.S.A. 2001) 3
  4. Evidence for in vivo production of Humanin peptide, a neuroprotective factor against Alzheimer's disease-related insults. (PMID: 12009529) Tajima H. … Nishimoto I. (Neurosci. Lett. 2002) 3
  5. Humanin peptide suppresses apoptosis by interfering with Bax activation. (PMID: 12732850) Guo B. … Reed J.C. (Nature 2003) 3

Products for MTRNR2L10 Gene

Sources for MTRNR2L10 Gene

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