Aliases for MTRF1 Gene
External Ids for MTRF1 Gene
Previous GeneCards Identifiers for MTRF1 Gene
The protein encoded by this gene was determined by in silico methods to be a mitochondrial protein with similarity to the peptide chain release factors (RFs) discovered in bacteria and yeast. The peptide chain release factors direct the termination of translation in response to the peptide chain termination codons. Initially thought to have a role in the termination of mitochondria protein synthesis, a recent publication found no mitochondrial translation release functionality. Multiple alternatively spliced transcript variants have been suggested by mRNA and EST data; however, their full-length natures are not clear. [provided by RefSeq, Jul 2008]
GeneCards Summary for MTRF1 Gene
MTRF1 (Mitochondrial Translation Release Factor 1) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include nucleotide binding and translation release factor activity, codon specific. An important paralog of this gene is MTRF1L.
UniProtKB/Swiss-Prot for MTRF1 Gene
Mitochondrial peptide chain release factor that directs the termination of translation in response to the peptide chain non-cognate termination stop codons AGG and AGA.