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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

MTRF1 Gene

protein-coding   GIFtS: 54
GCID: GC13M041790

Mitochondrial Translational Release Factor 1

Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Mitochondrial Translational Release Factor 11 2     RF12
Mitochontrial Peptide Chain Release Factor 11 2     mtRF-12
MRF-12 3     Peptide Chain Release Factor 1, Mitochondrial2
MRF12     MtRF-13
MTTRF12     

External Ids:    HGNC: 74691   Entrez Gene: 96172   Ensembl: ENSG000001206627   OMIM: 6046015   UniProtKB: O755703   

Export aliases for MTRF1 gene to outside databases

Previous GC identifers: GC13M039777 GC13M035777 GC13M040727 GC13M039588 GC13M040689 GC13M022590


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for MTRF1 Gene:
The protein encoded by this gene was determined by in silico methods to be a mitochondrial protein with similarity
to the peptide chain release factors (RFs) discovered in bacteria and yeast. The peptide chain release factors
direct the termination of translation in response to the peptide chain termination codons. Initially thought to
have a role in the termination of mitochondria protein synthesis, a recent publication found no mitochondrial
translation release functionality. Multiple alternatively spliced transcript variants have been suggested by mRNA
and EST data; however, their full-length natures are not clear. (provided by RefSeq, Jul 2008)

GeneCards Summary for MTRF1 Gene: 
MTRF1 (mitochondrial translational release factor 1) is a protein-coding gene. Diseases associated with MTRF1 include ophthalmoplegia, and optic atrophy. GO annotations related to this gene include translation release factor activity, codon specific and translation release factor activity. An important paralog of this gene is MTRF1L.

UniProtKB/Swiss-Prot: RF1M_HUMAN, O75570
Function: Mitochondrial peptide chain release factor that directs the termination of translation in response to
the peptide chain non-cognate termination stop codons AGG and AGA

Gene Wiki entry for MTRF1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000013.10  NT_024524.14  NC_018924.2  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for MTRF1
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMTRF1 promoter sequence
   Search SABiosciences Chromatin IP Primers for MTRF1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MTRF1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 13q14.1-q14.3   Ensembl cytogenetic band:  13q14.11   HGNC cytogenetic band: 13q14.1-q14.3

MTRF1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MTRF1 gene location

GeneLoc information about chromosome 13         GeneLoc Exon Structure

GeneLoc location for GC13M041790:  view genomic region     (about GC identifiers)

Start:
41,790,505 bp from pter      End:
41,837,742 bp from pter
Size:
47,238 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: RF1M_HUMAN, O75570 (See protein sequence)
Recommended Name: Peptide chain release factor 1, mitochondrial precursor  
Size: 445 amino acids; 52306 Da
Subcellular location: Mitochondrion
Secondary accessions: Q5T6Y5 Q8IUQ6

Explore the universe of human proteins at neXtProt for MTRF1: NX_O75570

Explore proteomics data for MTRF1 at MOPED 

Post-translational modifications:

  • UniProtKB: Methylation of glutamine in the GGQ triplet is conserved from bacteria to mammals (By similarity)
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_O75570

  • MTRF1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    MTRF1 Protein Expression
    REFSEQ proteins: NP_004285.2  
    ENSEMBL proteins: 
     ENSP00000368793   ENSP00000368790   ENSP00000399279   ENSP00000400031  

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    Cloud-Clone Corp. Proteins for MTRF1 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm ----
    GO:0005739mitochondrion IEA--

    MTRF1 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    3 InterPro protein domains:
     IPR014720 dsRNA-bd-like_dom
     IPR005139 PCRF
     IPR000352 Pep_chain_release_fac_I_II

    Graphical View of Domain Structure for InterPro Entry O75570

    ProtoNet protein and cluster: O75570

    1 Blocks protein domain: IPB000352 Class I peptide chain release factor domain

    UniProtKB/Swiss-Prot: RF1M_HUMAN, O75570
    Similarity: Belongs to the prokaryotic/mitochondrial release factor family


    MTRF1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RF1M_HUMAN, O75570
    Function: Mitochondrial peptide chain release factor that directs the termination of translation in response to
    the peptide chain non-cognate termination stop codons AGG and AGA

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003747translation release factor activity TAS9838146
    GO:0016149translation release factor activity, codon specific IEA--
         
    MTRF1 for ontologies           About GeneDecksing


    Phenotypes:
         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Mtrf1):
     hematopoietic system 

    MTRF1 for phenotypes           About GeneDecksing

    Animal Models:
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MTRF1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 16)

    5/16 Interacting proteins for MTRF1 (O755703 ENSP000003687904) via UniProtKB, MINT, STRING, and/or I2D (see all 16)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MYCP011063, ENSP000003672074I2D: score=1 STRING: ENSP00000367207
    PARK7Q994973, ENSP000003402784I2D: score=1 STRING: ENSP00000340278
    RPS20ENSP000000095894STRING: ENSP00000009589
    MRPS16ENSP000003620364STRING: ENSP00000362036
    RPS16ENSP000002514534STRING: ENSP00000251453
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006415translational termination ----
    GO:0006449regulation of translational termination TAS9838146

    MTRF1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for MTRF1 (RF1M)

    Search CenterWatch for drugs/clinical trials and news about MTRF1 / RF1M

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for MTRF1 gene: 
    NM_004294.2  

    Unigene Cluster for MTRF1:

    Mitochondrial translational release factor 1
    Hs.382176  [show with all ESTs]
    Unigene Representative Sequence: BC038427
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000379480(uc001uxy.3 uc001uxz.3 uc010tff.2) ENST00000473492
    ENST00000379477(uc001uxx.3) ENST00000239852 ENST00000480434 ENST00000452359
    ENST00000497679 ENST00000492827 ENST00000498245 ENST00000430347(uc001uyc.1)

    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
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    hsa-miR-138-1* hsa-miR-3164 hsa-miR-579 hsa-miR-4311 hsa-miR-130b*
    SwitchGear 3'UTR luciferase reporter plasmidMTRF1 3' UTR sequence
    Inhib. RNA
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    Additional mRNA sequence: 

    AF072934.1 AK055086.1 AK294343.1 BC027731.2 BC038427.1 BC042196.1 BC065496.1 

    15 DOTS entries:

    DT.410020  DT.97818650  DT.95186214  DT.91989067  DT.100754099  DT.120794044  DT.120794077  DT.120794082 
    DT.120794066  DT.40287987  DT.95309200  DT.95368323  DT.99928783  DT.120794065  DT.91865335 

    24/73 AceView cDNA sequences (see all 73):

    AI051946 BC042196 AI802069 NM_004294 CF528940 AW572070 AI499198 AI075047 
    AA573449 CK821811 BC027731 AA805424 AA496969 AI884353 BM280337 AI432457 
    BQ013968 BC038427 AW241988 CK821812 AA406632 AW274255 BM312083 BX480457 

    GeneLoc Exon Structure

    5/11 Alternative Splicing Database (ASD) splice patterns (SP) for MTRF1 (see all 11)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b ^ 4a · 4b · 4c · 4d ^ 5a · 5b · 5c · 5d · 5e ^ 6 ^ 7 ^ 8 ^ 9a · 9b · 9c ^ 10 ^ 11 ^ 12 ^ 13 ^
    SP1:                          -           -           -     -     -                                   -                       -     -                           
    SP2:                    -     -     -     -     -     -     -     -                                                           -     -                           
    SP3:                    -     -     -     -     -     -     -     -                                   -                       -     -                           
    SP4:                    -           -     -     -     -     -     -                                   -                                                         
    SP5:                                            -     -     -     -                                                                                             

    ExUns: 14a · 14b
    SP1:            
    SP2:            
    SP3:            
    SP4:            
    SP5:            


    ECgene alternative splicing isoforms for MTRF1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    MTRF1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTAAAGTTAA
    MTRF1 Expression
    About this image


    See MTRF1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for MTRF1

    SOURCE GeneReport for Unigene cluster: Hs.382176
        SABiosciences Custom PCR Arrays for MTRF1
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for MTRF1 gene from 10/16 species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Mtrf11 , 5 mitochondrial translational release factor 11, 5 84.49(n)1
    82.02(a)1
      14 (42.63 cM)5
    2112531  NM_145960.41  NP_666072.31 
     793977725 
    chicken
    (Gallus gallus)
    Aves MTRF11 mitochondrial translational release factor 1 68.82(n)
    66.74(a)
      418830  XM_417026.3  XP_417026.1 
    lizard
    (Anolis carolinensis)
    Reptilia MTRF16
    mitochondrial translational release factor 1
    58(a)
    1 ↔ 1
    3(70640277-70663330)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.105312 Xenopus laevis transcribed sequence with weak similarity to protein spO75570 (H.sapiens) RF1M_HUMAN Mitochondrial peptide chain release factor 1 precursor (MRF-1) less 76.47(n)    BJ633445.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc:1131041 zgc:113104 63.39(n)
    67.52(a)
      503530  NM_001012494.1  NP_001012512.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG57053 translational termination translation
    release factor, codon specific less
    37(a)   34A10   --
    worm
    (Caenorhabditis elegans)
    Secernentea W03F8.33 protein releasing factor 34(a)   IV(5187349-5189186)   --
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes MRF16
    Mitochondrial translation release factor, involved...
    28(a)
    1 → many
    VII(234717-235958)
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT2G470201 Peptide chain release factor 1 48.49(n)
    39.27(a)
      819316  NM_130270.3  NP_182225.3 
    rice
    (Oryza sativa)
    Liliopsida Os05g02773001 hypothetical protein 49.53(n)
    45.17(a)
      4338281  NM_001061615.1  NP_001055080.1 


    ENSEMBL Gene Tree for MTRF1 (if available)
    TreeFam Gene Tree for MTRF1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for MTRF1 gene
    MTRF1L2  
    1 SIMAP similar gene for MTRF1 using alignment to 3 protein entries:     RF1M_HUMAN (see all proteins):
    MTRF1L

    MTRF1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1068 SNPs in MTRF1 are shown (see all 1068)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 13 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1509391911,2
    C,Funtested141814531(+) GACACC/TGTCAC 2 S G mis12Minor allele frequency- T:0.01NA EU 5873
    rs1889645541,2
    --41790079(+) TGCCCA/GGCTAG 1 -- ds50010--------
    rs1448049991,2
    --41790162(+) CTGCCC/TGCCTC 1 -- ds50010--------
    rs1485288351,2
    C--41790183(+) AGTGCC/TGGGAT 1 -- ds50010--------
    rs1129686781,2
    F--41790184(+) GTGCTA/GGGATT 1 -- ds50011Minor allele frequency- G:0.00CSA 1
    rs3735880371,2
    C--41790393(+) ATTAC-/CACACATC 1 -- cds10--------
    rs30720511,2
    C--41790395(+) TACACCAC/-ATCTA 1 -- cds11Minor allele frequency- -:0.00NA 2
    rs2009253021,2
    C--41790483(-) TATTTC/TTTTTT 1 -- ds50010--------
    rs1118509291,2
    C,F--41790533(+) GTTTAC/TATAGT 1 -- ut311Minor allele frequency- T:0.50NA 2
    rs1399998481,2
    C--41790577(+) GTCTGC/TACCCA 1 -- ut310--------

    HapMap Linkage Disequilibrium report for MTRF1 (41790505 - 41837742 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for MTRF1:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2747301CNV Deletion23290073
    nsv1015CNV Insertion18451855
    nsv1014CNV Insertion18451855
    nsv832587CNV Gain17160897

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 604601    OMIM disorders: --

    4 diseases for MTRF1:    About MalaCards
    ophthalmoplegia    optic atrophy    pneumonia    tuberculosis

    2 diseases from the University of Copenhagen DISEASES database for MTRF1:
    Leigh disease     Ophthalmoplegia

    MTRF1 for disorders           About GeneDecksing

    1 Novoseek inferred disease relationship for MTRF1 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    sterility male 83.6 3 14968308 (1), 17622268 (1), 12782297 (1)

    Genetic Association Database (GAD): MTRF1
    Human Genome Epidemiology (HuGE) Navigator: MTRF1 (1 document)

    Export disorders for MTRF1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for MTRF1 gene, integrated from 9 sources (see all 18):
    (articles sorted by number of sources associating them with MTRF1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification and cloning of human mitochondrial translational release factor 1 and the ribosome recycling factor. (PubMed id 9838146)1, 2, 3 Zhang Y. and Spremulli L.L. (1998)
    2. Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (2010)
    3. mtRF1a is a human mitochondrial translation release factor decoding the major termination codons UAA and UAG. (PubMed id 17803939)1, 2 Soleimanpour-Lichaei H.R....Chrzanowska-Lightowlers Z. (2007)
    4. The DNA sequence and analysis of human chromosome 13. (PubMed id 15057823)1, 2 Dunham A.... Ross M.T. (2004)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. Assignment of the human mitochondrial translational release factor 1 (MTRF1) to chromosome 13q14.1-->q14.3 and of the human mitochondrial ribosome recycling factor (MRRF) to chromosome 9q32-->q34.1 with radiation hybrid mapping. (PubMed id 10773675)1, 3 Hansen L.L....Justesen J. (2000)
    7. DJ-1 enhances cell survival through the binding of cezanne, a negative regulator of NF-{kappa}B. (PubMed id 21097510)1 McNally R.S.... Ting J.P. (2010)
    8. Mutations in C12orf65 in patients with encephalomyopa thy and a mitochondrial translation defect. (PubMed id 20598281)1 Antonicka H....Shoubridge E.A. (2010)
    9. HMRF1L is a human mitochondrial translation release factor involved in the decoding of the termination codons UAA and UAG. (PubMed id 18429816)1 Nozaki Y....Takeuchi N. (2008)
    10. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 9617 HGNC: 7469 AceView: MTRF1 Ensembl:ENSG00000120662 euGenes: HUgn9617
    ECgene: MTRF1 H-InvDB: MTRF1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for MTRF1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for MTRF1 gene:
    Search GeneIP for patents involving MTRF1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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