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MTRF1 Gene

protein-coding   GIFtS: 55
GCID: GC13M041790

Mitochondrial Translational Release Factor 1

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Mitochondrial Translational Release Factor 11 2     RF12
Mitochontrial Peptide Chain Release Factor 11 2     mtRF-12
MRF-12 3     Peptide Chain Release Factor 1, Mitochondrial2
MRF12     MtRF-13
MTTRF12     

External Ids:    HGNC: 74691   Entrez Gene: 96172   Ensembl: ENSG000001206627   OMIM: 6046015   UniProtKB: O755703   

Export aliases for MTRF1 gene to outside databases

Previous GC identifers: GC13M039777 GC13M035777 GC13M040727 GC13M039588 GC13M040689 GC13M022590


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for MTRF1 Gene:
The protein encoded by this gene was determined by in silico methods to be a mitochondrial protein with similarity
to the peptide chain release factors (RFs) discovered in bacteria and yeast. The peptide chain release factors
direct the termination of translation in response to the peptide chain termination codons. Initially thought to
have a role in the termination of mitochondria protein synthesis, a recent publication found no mitochondrial
translation release functionality. Multiple alternatively spliced transcript variants have been suggested by mRNA
and EST data; however, their full-length natures are not clear. (provided by RefSeq, Jul 2008)

GeneCards Summary for MTRF1 Gene:
MTRF1 (mitochondrial translational release factor 1) is a protein-coding gene. GO annotations related to this gene include translation release factor activity, codon specific and translation release factor activity. An important paralog of this gene is MTRF1L.

UniProtKB/Swiss-Prot: RF1M_HUMAN, O75570
Function: Mitochondrial peptide chain release factor that directs the termination of translation in response to
the peptide chain non-cognate termination stop codons AGG and AGA

Gene Wiki entry for MTRF1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000013.10  NT_024524.15  NC_018924.2  
Regulatory elements:
   Search for regulatory transcription factor binding sites for MTRF1
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMTRF1 promoter sequence
   Search Chromatin IP Primers for MTRF1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MTRF1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 13q14.1-q14.3   Ensembl cytogenetic band:  13q14.11   HGNC cytogenetic band: 13q14.1-q14.3

MTRF1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MTRF1 gene location

GeneLoc information about chromosome 13         GeneLoc Exon Structure

GeneLoc location for GC13M041790:  view genomic region     (about GC identifiers)

Start:
41,790,505 bp from pter      End:
41,837,742 bp from pter
Size:
47,238 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: RF1M_HUMAN, O75570 (See protein sequence)
Recommended Name: Peptide chain release factor 1, mitochondrial precursor  
Size: 445 amino acids; 52306 Da
Secondary accessions: Q5T6Y5 Q8IUQ6

Explore the universe of human proteins at neXtProt for MTRF1: NX_O75570

Explore proteomics data for MTRF1 at MOPED

Post-translational modifications: 

  • Methylation of glutamine in the GGQ triplet is conserved from bacteria to mammals (By similarity)1
  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See MTRF1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_004285.2  
    ENSEMBL proteins: 
     ENSP00000368793   ENSP00000368790   ENSP00000399279   ENSP00000400031  

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    antibodies-online peptides for MTRF1

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    3 InterPro protein domains:
     IPR014720 dsRNA-bd_dom
     IPR005139 PCRF
     IPR000352 Pep_chain_release_fac_I_II

    Graphical View of Domain Structure for InterPro Entry O75570

    ProtoNet protein and cluster: O75570

    1 Blocks protein domain: IPB000352 Class I peptide chain release factor domain

    UniProtKB/Swiss-Prot: RF1M_HUMAN, O75570
    Similarity: Belongs to the prokaryotic/mitochondrial release factor family


    Find genes that share domains with MTRF1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RF1M_HUMAN, O75570
    Function: Mitochondrial peptide chain release factor that directs the termination of translation in response to
    the peptide chain non-cognate termination stop codons AGG and AGA

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003747translation release factor activity TAS9838146
    GO:0016149translation release factor activity, codon specific IEA--
         
    Find genes that share ontologies with MTRF1           About GenesLikeMe


    Phenotypes:
         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Mtrf1):
     hematopoietic system 

    Find genes that share phenotypes with MTRF1           About GenesLikeMe

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for MTRF1

    miRNA
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    miRTarBase miRNAs that target MTRF1:
    hsa-mir-26a-5p (MIRT050076), hsa-mir-18a-3p (MIRT040962)

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    RF1M_HUMAN, O75570: Mitochondrion
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    mitochondrion5
    cytosol2

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm ----
    GO:0005739mitochondrion IEA--

    Find genes that share ontologies with MTRF1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for MTRF1
    Interactions:

        Search GeneGlobe Interaction Network for MTRF1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for MTRF1 (O755703 ENSP000003687904) via UniProtKB, MINT, STRING, and/or I2D (see all 49)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MYCP011063, ENSP000003672074I2D: score=1 STRING: ENSP00000367207
    PARK7Q994973, ENSP000003402784I2D: score=1 STRING: ENSP00000340278
    MRPS16ENSP000003620364STRING: ENSP00000362036
    RPS13ENSP000002281404STRING: ENSP00000228140
    RPS20ENSP000000095894STRING: ENSP00000009589
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006415translational termination ----
    GO:0006449regulation of translational termination TAS9838146

    Find genes that share ontologies with MTRF1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for MTRF1 (RF1M)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for MTRF1 gene: 
    NM_004294.2  

    Unigene Cluster for MTRF1:

    Mitochondrial translational release factor 1
    Hs.382176  [show with all ESTs]
    Unigene Representative Sequence: BC038427
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000379480(uc001uxy.3 uc001uxz.3 uc010tff.2) ENST00000473492
    ENST00000379477(uc001uxx.3) ENST00000239852 ENST00000480434 ENST00000452359
    ENST00000497679 ENST00000492827 ENST00000498245 ENST00000430347(uc001uyc.1)

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    Additional mRNA sequence: 

    AF072934.1 AK055086.1 AK294343.1 BC027731.2 BC038427.1 BC042196.1 BC065496.1 

    15 DOTS entries:

    DT.410020  DT.97818650  DT.95186214  DT.91989067  DT.100754099  DT.120794044  DT.120794077  DT.120794082 
    DT.120794066  DT.40287987  DT.95309200  DT.95368323  DT.99928783  DT.120794065  DT.91865335 

    Selected AceView cDNA sequences (see all 73):

    AA573449 AI802069 AI884353 BC042196 AW572070 AA805424 CF528940 BC027731 
    AI051946 AI075047 AA496969 CK821811 NM_004294 BM280337 AI499198 BM312083 
    AW612002 BP377446 BX956016 AK055086 BF447912 AA490567 BX099180 AI248927 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for MTRF1 (see all 11)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b ^ 4a · 4b · 4c · 4d ^ 5a · 5b · 5c · 5d · 5e ^ 6 ^ 7 ^ 8 ^ 9a · 9b · 9c ^ 10 ^ 11 ^ 12 ^ 13 ^
    SP1:                          -           -           -     -     -                                   -                       -     -                           
    SP2:                    -     -     -     -     -     -     -     -                                                           -     -                           
    SP3:                    -     -     -     -     -     -     -     -                                   -                       -     -                           
    SP4:                    -           -     -     -     -     -     -                                   -                                                         
    SP5:                                            -     -     -     -                                                                                             

    ExUns: 14a · 14b
    SP1:            
    SP2:            
    SP3:            
    SP4:            
    SP5:            


    ECgene alternative splicing isoforms for MTRF1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    MTRF1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTAAAGTTAA
    MTRF1 Expression
    About this image


    MTRF1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Blood (Hematopoietic System)
             T-Cytotoxic Cells Peripheral Blood
    MTRF1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    MTRF1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.382176
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for MTRF1 gene from Selected species (see all 18)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Mtrf11 , 5 mitochondrial translational release factor 11, 5 84.49(n)1
    82.02(a)1
      14 (42.63 cM)5
    2112531  NM_145960.41  NP_666072.31 
     793977725 
    chicken
    (Gallus gallus)
    Aves MTRF11 mitochondrial translational release factor 1 68.82(n)
    66.59(a)
      418830  XM_417026.4  XP_417026.2 
    lizard
    (Anolis carolinensis)
    Reptilia MTRF16
    mitochondrial translational release factor 1
    59(a)
    1 ↔ 1
    3(70640277-70663330)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.105312 Xenopus laevis transcribed sequence with weak similarity more 76.47(n)    BJ633445.1 
    zebrafish
    (Danio rerio)
    Actinopterygii mtrf11 mitochondrial translational release factor 1 63.39(n)
    67.52(a)
      503530  NM_001012494.1  NP_001012512.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG57053 translational termination translation
    release more
    37(a)   34A10   --
    worm
    (Caenorhabditis elegans)
    Secernentea W03F8.33 protein releasing factor 34(a)   IV(5187349-5189186)   --
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes MRF16
    Mitochondrial translation release factor, involved...
    31(a)
    1 → many
    VII(234717-235958) YGL143C
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT2G470201 AT2G47020 52.66(n)
    45.6(a)
      819316  NM_130270.3  NP_182225.3 
    rice
    (Oryza sativa)
    Liliopsida Os05g02773001 Os05g0277300 50.63(n)
    46.54(a)
      4338281  NM_001061615.1  NP_001055080.1 


    ENSEMBL Gene Tree for MTRF1 (if available)
    TreeFam Gene Tree for MTRF1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for MTRF1 gene
    MTRF1L2  
    1 SIMAP similar gene for MTRF1 using alignment to 3 protein entries:     RF1M_HUMAN (see all proteins):
    MTRF1L

    Find genes that share paralogs with MTRF1           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for MTRF1 (see all 1068)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 13 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1509391911,2
    C,Funtested141814531(+) GACACC/TGTCAC 2 S G mis12Minor allele frequency- T:0.01NA EU 5873
    rs1889645541,2
    --41790079(+) TGCCCA/GGCTAG 1 -- ds50010--------
    rs1448049991,2
    --41790162(+) CTGCCC/TGCCTC 1 -- ds50010--------
    rs1485288351,2
    C--41790183(+) AGTGCC/TGGGAT 1 -- ds50010--------
    rs1129686781,2
    F--41790184(+) GTGCTA/GGGATT 1 -- ds50011Minor allele frequency- G:0.00CSA 1
    rs3735880371,2
    C--41790393(+) ATTAC-/CACACATC 1 -- cds10--------
    rs30720511,2
    C--41790395(+) TACACCAC/-ATCTA 1 -- cds11Minor allele frequency- -:0.00NA 2
    rs2009253021,2
    C--41790483(-) TATTTC/TTTTTT 1 -- ds50010--------
    rs1118509291,2
    C,F--41790533(+) GTTTAC/TATAGT 1 -- ut311Minor allele frequency- T:0.50NA 2
    rs1399998481,2
    C--41790577(+) GTCTGC/TACCCA 1 -- ut310--------

    HapMap Linkage Disequilibrium report for MTRF1 (41790505 - 41837742 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for MTRF1:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2747301CNV Deletion23290073
    nsv1015CNV Insertion18451855
    nsv1014CNV Insertion18451855
    nsv832587CNV Gain17160897

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 604601    OMIM disorders: --

    2 diseases from the University of Copenhagen DISEASES database for MTRF1:
    Leigh disease     Ophthalmoplegia

    Find genes that share disorders with MTRF1           About GenesLikeMe

    1 Novoseek inferred disease relationship for MTRF1 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    sterility male 83.6 3 14968308 (1), 17622268 (1), 12782297 (1)

    Genetic Association Database (GAD): MTRF1
    Human Genome Epidemiology (HuGE) Navigator: MTRF1 (1 document)

    Export disorders for MTRF1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for MTRF1 gene, integrated from 10 sources (see all 18):
    (articles sorted by number of sources associating them with MTRF1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification and cloning of human mitochondrial translational release factor 1 and the ribosome recycling factor. (PubMed id 9838146)1, 2, 3 Zhang Y. and Spremulli L.L. (Biochim. Biophys. Acta 1998)
    2. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (PLoS ONE 2010)
    3. mtRF1a is a human mitochondrial translation release factor decoding the major termination codons UAA and UAG. (PubMed id 17803939)1, 2 Soleimanpour-Lichaei H.R....Chrzanowska-Lightowlers Z. (Mol. Cell 2007)
    4. The DNA sequence and analysis of human chromosome 13. (PubMed id 15057823)1, 2 Dunham A.... Ross M.T. (Nature 2004)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. Assignment of the human mitochondrial translational release factor 1 (MTRF1) to chromosome 13q14.1--&gt;q14.3 and of the human mitochondrial ribosome recycling factor (MRRF) to chromosome 9q32--&gt;q34.1 with radiation hybrid mapping. (PubMed id 10773675)1, 3 Hansen L.L....Justesen J. (Cytogenet. Cell Genet. 2000)
    7. DJ-1 enhances cell survival through the binding of cezanne, a negative regulator of NF-{kappa}B. (PubMed id 21097510)1 McNally R.S.... Ting J.P. (J. Biol. Chem. 2011)
    8. Mutations in C12orf65 in patients with encephalomyopathy and a mitochondrial translation defect. (PubMed id 20598281)1 Antonicka H.... Shoubridge E.A. (Am. J. Hum. Genet. 2010)
    9. HMRF1L is a human mitochondrial translation release factor involved in the decoding of the termination codons UAA and UAG. (PubMed id 18429816)1 Nozaki Y....Takeuchi N. (amp 2008)
    10. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (Nat. Genet. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

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    Entrez Gene: 9617 HGNC: 7469 AceView: MTRF1 Ensembl:ENSG00000120662 euGenes: HUgn9617
    ECgene: MTRF1 H-InvDB: MTRF1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for MTRF1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for MTRF1 gene:
    Search GeneIP for patents involving MTRF1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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