MTO1 Gene
protein-coding GIFtS: 53
GCID: GC06P074171
|
|
mitochondrial translation optimization 1 homolog (S. cerevisiae)
| |
Aliases for MTO1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Mitochondrial Translation Optimization 1 Homolog (S. Cerevisiae)1 2 | | Protein MTO1 Homolog, Mitochondrial2 | | COXPD102 | | EC 1.1.1.408 | | Homolog Of Yeast Mto12 | | EC 6.3.58 | | Mitochondrial MTO1-32 | | |
Export aliases for MTO1 gene to outside databasesPrevious GC identifers: GC06P074129 GC06P074167 GC06P074228 GC06P071369 |
Summaries for MTO1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for MTO1: This gene encodes a mitochondrial protein thought to be involved in mitochondrial tRNA modification. The encodedprotein may also play a role in the expression of the non-syndromic and aminoglycoside-induced deafness phenotypesassociated with a specific mutation in the mitochondrial 12S rRNA gene. Multiple transcript variants encodingdifferent isoforms have been found for this gene. (provided by RefSeq, Jul 2008) UniProtKB/Swiss-Prot: MTO1_HUMAN, Q9Y2Z2Function: Involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U34) of the wobble uridine base inmitochondrial tRNAs Gene Wiki entry for MTO1
|
Genomic Views for MTO1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000006.11 NC_018917.1 NT_007299.13
Regulatory elements: Search SABiosciences Regulatory transcription factor binding sites for MTO1 Other transcription factors
Search SABiosciences Chromatin IP Primers for MTO1
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MTO1 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 6q13 Ensembl cytogenetic band: 6q13 HGNC cytogenetic band: 6q14.1MTO1 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 6 GeneLoc Exon Structure GeneLoc location for GC06P074171: view genomic region
(about GC identifiers)
Start:
|
74,171,301 bp from pter |
End:
|
74,218,959 bp from pter |
Size:
|
47,659 bases |
Orientation:
|
plus strand |
|
Proteins for MTO1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: MTO1_HUMAN, Q9Y2Z2 (See
protein sequence)Recommended Name: Protein MTO1 homolog, mitochondrial precursor Size: 717 amino acids; 79964 Da
Cofactor: FAD (By similarity)
Subcellular location: Mitochondrion (By similarity)
Sequence caution: Sequence=AAD27712.1; Type=Frameshift; Positions=9; Sequence=AAH05808.2; Type=Erroneous initiation;Note=Translation N-terminally shortened;
Secondary accessions: B3KQB5 Q5SWL2 Q5SWL3 Q5SWL4 Q8NDN7 Q8WZ57 Q96FE6 Q9BS06Alternative splicing: 6 isoforms: Q9Y2Z2-1 Q9Y2Z2-2 Q9Y2Z2-3 Q9Y2Z2-4 Q9Y2Z2-5 Q9Y2Z2-6 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for MTO1: NX_Q9Y2Z2
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9Y2Z2 2 DME Specific Peptides for MTO1 (Q9Y2Z2)
MTO1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001116698.1 NP_036255.2 NP_598400.1 ENSEMBL proteins: ENSP00000402038 ENSP00000419561 ENSP00000396529 ENSP00000359328 ENSP00000428302 ENSP00000416397 ENSP00000359323 ENSP00000428903 ENSP00000407580 ENSP00000430660 ENSP00000428863 ENSP00000429595 Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005739 | mitochondrion |
IEA | -- |
MTO1 for ontologies About GeneDecksing
MTO1 Antibody Products: Assay Products for MTO1: |
Protein
Domains / Families for MTO1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
MTO1 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9Y2Z2ProtoNet protein and cluster: Q9Y2Z2 1 Blocks protein family: IPB002218 Glucose-inhibited division protein
UniProtKB/Swiss-Prot: MTO1_HUMAN, Q9Y2Z2Similarity: Belongs to the MnmG family |
Function for MTO1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Function Summary: UniProtKB/Swiss-Prot: MTO1_HUMAN, Q9Y2Z2Function: Involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U34) of the wobble uridine base inmitochondrial tRNAsEnzyme Numbers (IUBMB): EC 6.3.52 EC 1.1.1.402
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MTO1 (see all 6) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MTO1 (see all 4) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): MTO1 (NM_001123226) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MTO1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MTO1  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MTO1 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0050660 | flavin adenine dinucleotide binding |
IEA | -- |
MTO1 for ontologies About GeneDecksing
|
Pathways & Interactions for MTO1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MTO1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 7)
 5/36 Interacting proteins for MTO1 (Q9Y2Z23 ENSP000004020384) via UniProtKB, MINT, STRING, and/or I2D (see all 36)About this table
Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0002098 | tRNA wobble uridine modification |
-- | -- | | GO:0008033 | tRNA processing |
-- | -- | | GO:0055114 | oxidation-reduction process |
IEA | -- | | GO:0070899 | mitochondrial tRNA wobble uridine modification |
IEA | -- |
MTO1 for ontologies About GeneDecksing
|
Drugs & Compounds for MTO1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Browse Tocris compounds for MTO1
1 HMDB Compound for MTO1 About this table
| Compound | Synonyms |
CAS
# | PubMed Ids |
|---|
| FAD | 1H-Purin-6-amine flavin dinucleotide (see all 21) | 146-14-5 | -- | Search CenterWatch for drugs/clinical trials and news about MTO1 
|
Transcripts for MTO1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for MTO1 gene (3 alternative transcripts): NM_001123226.1 NM_012123.3 NM_133645.2 Unigene Cluster for MTO1: Mitochondrial translation optimization 1 homolog (S. cerevisiae) Hs.347614 [show with all ESTs]Unigene Representative Sequence: NM_00112322618/19 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 19): ENST00000415954 ENST00000498286(uc010kav.3 uc003pgz.4 uc003pha.4) ENST00000442897 ENST00000370305(uc010kaw.1) ENST00000521032 ENST00000370308 ENST00000415228 ENST00000370300(uc003pgy.4 uc003phb.4) ENST00000522205(uc003phc.1) ENST00000462039 ENST00000518210 ENST00000485082 ENST00000466977 ENST00000445187 ENST00000520366 ENST00000487960 ENST00000524046 ENST00000521156
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MTO1 (see all 6) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MTO1 (see all 4) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): MTO1 (NM_001123226) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MTO1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MTO1  |
Additional cDNA sequence: AF132937.1 AF319422.2 AF469110.1 AF469111.1 AK026073.1 AK074625.1 AK225828.1 AL833823.1 AY078985.1 AY078986.1 AY947715.1 AY947716.1 BC005808.2 BC011051.1 DQ656037.2 17 DOTS entries: DT.97855164 DT.455427 DT.100650931 DT.97795420 DT.100034226 DT.95234208 DT.95131199 DT.100650934 DT.100650932 DT.100650935 DT.100650919 DT.100872296 DT.121400859 DT.102842223 DT.121401059 DT.121401136 DT.121400519 24/204 AceView cDNA sequences (see all 204): BE070650 AK074625 BQ718226 AI160271 BQ002267 BX401352 BU165266 AK026073 BG177377 NM_133645 AY078985 BM807184 BG026018 CA309169 AU280169 AA573289 AA278420 BM707952 BM980628 H38254 CR605187 CA443179 AI560208 AF319422 GeneLoc Exon Structure
5/17 Alternative Splicing Database (ASD) splice patterns (SP) for MTO1 (see all 17) About this scheme
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | · | 2c | ^ | 3a | · | 3b | · | 3c | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7a | · | 7b | · | 7c | · | 7d | ^ | 8a | · | 8b | ^ | 9 | ^ | 10a | · | 10b | ^ | 11a | · | 11b | ^ | 12 | ^ | 13 | ^ | 14a | · | |
| SP1: | |   | |   | |   | |   | |   | - |   | - |   | - |   | |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | - |   | |
| SP2: | |   | |   | |   | |   | |   | - |   | - |   | - |   | |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | - |   | |   | - |   | - |   | |
| SP3: | |   | |   | |   | |   | |   | - |   | - |   | - |   | |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | - |   | |   | - |   | - |   | |
| SP4: | |   | |   | |   | |   | |   | - |   | - |   | - |   | |   | |   | - |   | - |   | - |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | - |   | - |   | |   | - |   | - |   | |
| SP5: | |   | |   | - |   | - |   | - |   | - |   | - |   | - |   | |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
| ExUns: | 14b | · | 14c | · | 14d | · | 14e | ^ | 15 | ^ | 16 | ^ | 17a | · | 17b | ^ | 18 | ^ | 19a | · | 19b | · | 19c | |
| SP1: | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for MTO1
|
Expression for MTO1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| MTO1 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: CAGATTTGCC
About this image See MTO1 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for MTO1
SOURCE GeneReport for Unigene cluster: Hs.347614 UniProtKB/Swiss-Prot: MTO1_HUMAN, Q9Y2Z2Tissue specificity: Ubiquitously expressed in various tissues, but with a markedly elevated expression in tissues ofhigh metabolic rates including cochlea SABiosciences Expression via Pathway-Focused PCR Array including MTO1:
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MTO1 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat MTO1 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MTO1 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MTO1 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MTO1 |
Orthologs for MTO1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the last universal common ancestor (LUCA).
Orthologs for MTO1 gene from 10/34 species (see all 34) About this table
ENSEMBL Gene Tree for MTO1 (if available) TreeFam Gene Tree for MTO1 (if available)  |
Paralogs for MTO1 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| -- |
Genomic Variants for MTO1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 6 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for MTO1 (74171301 - 74218959 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for MTO1: -- Human Gene Mutation Database (HGMD): MTO1
 | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MTO1 |
|
Disorders
/ Diseases for MTO1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
MTO1 for disorders About GeneDecksing
OMIM gene information: 614667
OMIM disorders: --
UniProtKB/Swiss-Prot: MTO1_HUMAN, Q9Y2Z2
Defects in MTO1 are the cause of combined oxidative phosphorylation deficiency type 10 (COXPD10) [MIM:614702].An autosomal recessive disorder resulting in variable defects of mitochondrial oxidative respiration. Affectedindividuals present in infancy with hypertrophic cardiomyopathy and lactic acidosis. The severity is variable, but canbe fatal in the most severe cases 5 diseases for MTO1: About MalaCardssensorineural hearing loss hearing loss diabetes mellitus pneumonia malaria 1 disease from the University of Copenhagen DISEASES database for MTO1:Nonsyndromic deafness Human Genome Epidemiology (HuGE) Navigator: MTO1 (3 documents) Export disorders for MTO1 gene to outside databases
|
Publications for MTO1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for MTO1 gene, integrated from 9 sources (see all 21): (articles sorted by number of sources associating them with MTO1) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Isolation and characterization of the putative nuclear modifier gene MTO1 involved in the pathogenesis of deafness-associated mitochondrial 12 S rRNA A1555G mutation. (PubMed id 12011058)1, 2, 3 Li X.M.... Guan M.-X. (2002)
- Mutations of the mitochondrial-tRNA modifier MTO1 caus e hypertrophic cardiomyopathy and lactic acidosis. (PubMed id 22608499)1, 2 Ghezzi D....Zeviani M. (2012)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (2003)
- Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. (PubMed id 10810093)1, 2 Lai C.H....Lin W. (2000)
- Study of modifiers factors associated to mitochondrial mutations in individuals with hearing impairment. (PubMed id 19338775)1, 9 de Moraes V.C....Sartorato E.L. (2009)
- Molecular characterization of putative modulatory factors in two Spanish families with A1555G deafness. (PubMed id 18391568)1, 9 Otaegui D....Lopez de Munain A. (2008)
- Phenotype of non-syndromic deafness associated with the mitochondrial A1555G mutation is modulated by mitochondrial RNA modifying enzymes MTO1 and GTPBP3. (PubMed id 15542390)1, 9 Bykhovskaya Y....Fischel-Ghodsian N. (2004)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
|
External Searches for MTO1 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing MTO1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing MTO1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing MTO1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for MTO1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for MTO1 gene: Search GeneIP for patents involving MTO1
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for MTO1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
|
 | |
 | |
 |
| | | | Browse OriGene Antibodies | | OriGene shRNA RFP for MTO1 | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MTO1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MTO1 | | OriGene Protein Over-expression Lysate for MTO1 | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for MTO1 | | OriGene 3'-UTR Clone for MTO1 | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MTO1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MTO1 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | OriGene Purified Protein for MTO1 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for MTO1 | | OriGene Custom Protein Services for MTO1 | | OriGene Custom Immunoassay Development | | |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MTO1 | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MTO1 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MTO1 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MTO1 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MTO1 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MTO1 |
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| | | Search Tocris compounds for MTO1 |
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 | | MTO1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MTO1 |
|  |  |  | | | Search ThermoFisher Antibodies for MTO1 |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MTO1 |
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