MTNR1B Gene
protein-coding GIFtS: 62
GCID: GC11P092705
|
|
melatonin receptor 1B
| |
Aliases
for MTNR1B gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Melatonin Receptor 1B1 2 | | MT22 | | Mel1b Receptor2 3 | | Melatonin Receptor MEL1B2 | | FGQTL22 | | Melatonin Receptor Type 1B2 | | MEL-1B-R2 | | Mel-1B-R3 |
Export aliases for MTNR1B gene to outside databasesPrevious GC identifers: GC11P095033 GC11P094210 GC11P092887 GC11P092390 GC11P092342 GC11P088793 |
Summaries
for MTNR1B gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for MTNR1B:
This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by thepineal gland. This gene product is an integral membrane protein that is a G-protein coupled, 7-transmembrane receptor.It is found primarily in the retina and brain although this detection requires RT-PCR. It is thought to participate inlight-dependent functions in the retina and may be involved in the neurobiological effects of melatonin. (provided byRefSeq, Jul 2008)
UniProtKB/Swiss-Prot: MTR1B_HUMAN, P49286Function: High affinity receptor for melatonin. Likely to mediates the reproductive and circadian actions of melatonin.The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclaseactivity
 summary
for MTNR1B: Melatonin receptors are a group of high affinity Gi/Go protein-coupled receptors, which are split into two
subtypes; MT1 and MT2. A third melatonin receptor, MT3, was proposed to exist but it has since been shown to
be the hamster homolog of human quinone reductase 2 and is therefore not considered within this GPCR
classification. MT1 and MT2 receptors are widely distributed with high concentrations found in the brain
(especially in the suprachiasmatic nucleus) and in the retina. Lower expression levels are seen in the
kidney, heart, lung and liver. Melatonin receptors regulate a variety of physiological and neuroendrocrine
functions including control of the endogenous circadian rhythm, thermoregulation and prolactin expression.
The human genes encoding MT1 and MT2 receptors are located on chromosome 4q35.1 and chromosome 11q21-22
respectively.
Gene Wiki entry for MTNR1B (Melatonin receptor 1B)
|
Genomic Views
for MTNR1B gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000011.9 NC_018922.1 NT_167190.1
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the MTNR1B gene promoter:
NF-1 Pbx1a Brachyury MIF-1 LCR-F1 AREB6 POU2F1 POU2F1a En-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for MTNR1B
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MTNR1B |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 11q21-q22 Ensembl cytogenetic band: 11q14.3 HGNC cytogenetic band: 11q21-q22MTNR1B Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 11 GeneLoc Exon Structure GeneLoc location for GC11P092705: view genomic region
(about GC identifiers)
Start:
|
92,702,789 bp from pter |
End:
|
92,718,232 bp from pter |
Size:
|
15,444 bases |
Orientation:
|
plus strand |
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Proteins
for MTNR1B gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: MTR1B_HUMAN, P49286 (See
protein sequence)Recommended Name: Melatonin receptor type 1B Size: 362 amino acids; 40188 Da
Subcellular location: Cell membrane; Multi-pass membrane proteinExplore the universe of human proteins at neXtProt for MTNR1B: NX_P49286
MTNR1B Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_005950.1
ENSEMBL proteins: ENSP00000257068 ENSP00000436101 ENSP00000433573 Reactome Protein details: P49286
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
MTNR1B for ontologies About GeneDecksing
MTNR1B Antibody Products:
Assay Products for MTNR1B: |
Protein
Domains /
Families
for MTNR1B gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
MTNR1B for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P49286ProtoNet protein and cluster: P49286 1 Blocks protein family: IPB000025 Melatonin receptor signature
UniProtKB/Swiss-Prot: MTR1B_HUMAN, P49286Similarity: Belongs to the G-protein coupled receptor 1 family |
Function
for MTNR1B gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: MTR1B_HUMAN, P49286Function: High affinity receptor for melatonin. Likely to mediates the reproductive and circadian actions of melatonin.The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclaseactivity Genatlas biochemistry entry for MTNR1B:melatonin receptor 1B,expressed in retina and brain,G protein coupled receptor superfamily
Clone
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OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MTNR1B
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In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MTNR1B |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0004930 | G-protein coupled receptor activity |
TAS | 7568007 | | GO:0008502 | melatonin receptor activity |
IEA | -- |
MTNR1B for ontologies About GeneDecksing
Animal Models:
Mouse knock-out Mtnr1btm1Drw for MTNR1B
1 MGI mutant phenotype (inferred from 1 allele ) (MGI details for Mtnr1b):
MTNR1B for phenotypes About GeneDecksing
|
Pathways & Interactions
for MTNR1B gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Class A/1 (Rhodopsin-like receptors) | | | 2 | Signaling by GPCR | | | 3 | Sweet Taste Signaling | | | 4 | Prostanoid ligand receptors | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for MTNR1B
2  BioSystems Pathways for MTNR1B
5/6 
Reactome Pathways for MTNR1B (see all 6)
1 
Kegg Pathway (Kegg details for MTNR1B):
MTNR1B for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for MTNR1B
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/162 Interacting proteins for MTNR1B (P492862, 3 ENSP000002570684) via UniProtKB, MINT, STRING, and/or I2D (see all 162)About this table
Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0007187 | G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger |
TAS | 7568007 | | GO:0007268 | synaptic transmission |
TAS | 7568007 | | GO:0042593 | glucose homeostasis |
IMP | -- | | GO:0050796 | regulation of insulin secretion |
IMP | -- |
MTNR1B for ontologies About GeneDecksing
|
Drugs & Compounds
for MTNR1B gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
MTNR1B for compounds About GeneDecksing
Compounds for MTNR1B available from Tocris Bioscience About this table
3 DrugBank Compounds for MTNR1B About this table
2 Novoseek chemical compound relationships for MTNR1B gene About this table
Search CenterWatch for drugs/clinical trials and news about MTNR1B / MTR1B
|
Transcripts
for MTNR1B gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for MTNR1B gene: NM_005959.3 Unigene Cluster for MTNR1B: Melatonin receptor 1B Hs.569039 [show with all ESTs]Unigene Representative Sequence: NM_0059593 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000257068(uc001pdk.1) ENST00000532482 ENST00000528076
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MTNR1B (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MTNR1B
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: MTNR1B (NM_005959) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MTNR1B | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MTNR1B |
Additional cDNA sequence: AF467654.1 AY114100.1 AY521019.1 BC069163.1 U25341.1 2 DOTS entries: DT.102821914 DT.101963086 12 AceView cDNA sequences: U25341 AI222420 BC069163 AY521019 CN842566 BF725791 NM_005959 BV169750 CN842471 CN835266 CN835231 BX118886
GeneLoc Exon Structure
|
Expression
for MTNR1B gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| MTNR1B expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GGTTCAGGCT
About this image
See MTNR1B Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for MTNR1B
SOURCE GeneReport for Unigene cluster: Hs.569039
UniProtKB/Swiss-Prot: MTR1B_HUMAN, P49286Tissue specificity: Expressed in retina and less in brain and hippocampus
SABiosciences Expression via Pathway-Focused PCR Arrays including MTNR1B:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MTNR1B
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat MTNR1B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MTNR1B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MTNR1B | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MTNR1B |
Orthologs
for MTNR1B gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for MTNR1B gene from 3/13 species (see all 13) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
MTNR1B1 |
melatonin receptor 1B |
68.77(n)
70.69(a) |
|
396338 XM_417201.2 XP_417201.2 |
lizard
(Anolis carolinensis) |
Reptilia |
MTNR1B6 |
-- |
68(a) |
1 ↔ 1 |
3(196737357-196738223) |
zebrafish
(Danio rerio) |
Actinopterygii |
mel1c2 |
melatonin receptor type 1C z2.3 |
76.59(n) |
|
30661 AY166825.1 |
ENSEMBL Gene Tree for MTNR1B (if available)
TreeFam Gene Tree for MTNR1B (if available) |
Paralogs
for MTNR1B gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for MTNR1B gene
- MTNR1A2 GPR502
2 SIMAP similar genes for MTNR1B using alignment to 5 protein entries: MTR1B_HUMAN (see all proteins):MTNR1A GPR50
MTNR1B for paralogs About GeneDecksing
|
Genomic Variants
for MTNR1B gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 11 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for MTNR1B (92702789 - 92718232 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 4 variations for MTNR1B
3 CNVs: 75754 37670 66034
1 Indel: 85931
Human Gene Mutation Database (HGMD): MTNR1B
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MTNR1B |
|
Disorders
/ Diseases
for MTNR1B gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
MTNR1B for disorders About GeneDecksing
OMIM gene information: 600804
OMIM disorders: --
18  diseases for MTNR1B: About MalaCardstardive dyskinesia autism spectrum disorder polycystic ovary syndrome scoliosis
gestational diabetes sleep disorder diabetes mellitus rheumatoid arthritis
pertussis alzheimer's disease arthritis breast cancer
atherosclerosis obesity schizophrenia melanoma
pancreatitis neuronitis
1 disease from the University of Copenhagen DISEASES database for MTNR1B:Diabetes mellitus 1 Novoseek disease relationship for MTNR1B gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| scoliosis idiopathic |
65.8 |
2 |
17632395 (2) |
Genetic Association Database (GAD): MTNR1B
Human Genome Epidemiology (HuGE) Navigator: MTNR1B (56 documents)
Export disorders for MTNR1B gene to outside databases
|
Publications
for MTNR1B gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for MTNR1B gene, integrated from 9 sources (see all 127):
(articles sorted by number of sources associating them with MTNR1B) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Molecular characterization of a second melatonin receptor expressed in human retina and brain: the Mel1b melatonin receptor. (PubMed id 7568007)1, 2, 9 Reppert S.M....Gusella J.F. (1995)
- Positive relationship between melatonin receptor type 1B polymorphism and rheumatoid factor in rheumatoid arthritis patients in the Korean population. (PubMed id 16098099)1, 4, 9 Ha E....Hong S.J. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Genetic polymorphisms of human melatonin 1b receptor gene in circadian rhythm sleep disorders and controls. (PubMed id 10696804)1, 2 Ebisawa T.... Yamauchi T. (2000)
- MTNR1B G24E variant associates With BMI and fasting p lasma glucose in the general population in studies of 22,142 Europeans. (PubMed id 20200315)1, 9 Andersson E.A....Hansen T. (2010)
- Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion. (PubMed id 19060908)1, 9 Lyssenko V....Groop L. (2009)
- A common variant in MTNR1B, encoding melatonin receptor 1B, is associated with type 2 diabetes and fasting plasma glucose in Han Chinese individuals. (PubMed id 19241057)1, 9 RAPnn T....Ling C. (2009)
- Melatonin receptor 1B (MTNR1B) gene polymorphism is associated with the occurrence of adolescent idiopathic scoliosis. (PubMed id 17632395)1, 9 Qiu X.S....Cheng J.C. (2007)
- Combined effects of single-nucleotide polymorphisms i n GCK, GCKR, G6PC2 and MTNR1B on fasting plasma glucose and type 2 diabetes ris k. (PubMed id 19533084)1, 9 Reiling E....'t Hart L.M. (2009)
- Variants in MTNR1B influence fasting glucose levels. (PubMed id 19060907)1, 9 Prokopenko I....Abecasis G.R. (2009)
|
External Searches for MTNR1B gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing MTNR1B gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing MTNR1B gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing MTNR1B gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for MTNR1B | Pharmacogenomics, SNPs, Pathways | | Wikipedia | http://en.wikipedia.org/wiki/Melatonin_receptor |
|
| | |
About This Section
| Patent Information for MTNR1B gene:
Search GeneIP for patents involving MTNR1B
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for MTNR1B gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for MTNR1B | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MTNR1B | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MTNR1B | | | OriGene Protein Over-expression Lysate for MTNR1B | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for MTNR1B | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MTNR1B | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MTNR1B | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MTNR1B | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MTNR1B | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MTNR1B | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MTNR1B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MTNR1B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MTNR1B |
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 |
 |
 | | | MTNR1B Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MTNR1B |
|  |  |  | | | | Search ThermoFisher Antibodies for MTNR1B |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MTNR1B |
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