MTMR3 Gene
protein-coding GIFtS: 61
GCID: GC22P030279
|
|
myotubularin related protein 3
| |
Aliases
for MTMR3 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Myotubularin Related Protein 31 2 | | FYVE Domain-Containing Dual Specificity Protein Phosphatase 12 3 | | FYVE-DSP11 2 3 | | EC 3.1.3.483 8 | | ZFYVE101 2 3 | | FYVE (Fab1 YGLO23 Vsp27 EEA1 Domain) Dual-Specificity Protein Phosphatase2 | | KIAA03711 3 | | Myotubularin-Related Protein 32 | | Zinc Finger FYVE Domain-Containing Protein 102 3 | | Zinc Finger, FYVE Domain Containing 102 |
Export aliases for MTMR3 gene to outside databasesPrevious GC identifers: GC22P026975 GC22P028603 GC22P013241 |
Summaries
for MTMR3 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for MTMR3:
This gene encodes a member of the myotubularin dual specificity protein phosphatase gene family. The encoded protein isstructurally similar to myotubularin but in addition contains a FYVE domain and an N-terminal PH-GRAM domain. Theprotein can self-associate and also form heteromers with another myotubularin related protein. The protein binds tophosphoinositide lipids through the PH-GRAM domain, and can hydrolyze phosphatidylinositol(3)-phosphate andphosphatidylinositol(3,5)-biphosphate in vitro. The encoded protein has been observed to have a perinuclear, possiblymembrane-bound, distribution in cells, but it has also been found free in the cytoplasm. Multiple transcript variantsencoding different isoforms have been found for this gene. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: MTMR3_HUMAN, Q13615Function: Phosphatase that acts on lipids with a phosphoinositol headgroup. Has phosphatase activity towardsphosphatidylinositol 3-phosphate and phosphatidylinositol 3,5-bisphosphate. May also dephosphorylate proteinsphosphorylated on Ser, Thr, and Tyr residues
Gene Wiki entry for MTMR3
|
Genomic Views
for MTMR3 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000022.10 NC_018933.1 NT_011520.12
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the MTMR3 gene promoter:
SREBP-1a Pbx1a AML1a Pax-5 MAZR IRF-1 Cdc5 SREBP-1b
Other transcription factors
Search SABiosciences Chromatin IP Primers for MTMR3
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MTMR3 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 22q12.2 Ensembl cytogenetic band: 22q12.2 HGNC cytogenetic band: 22q12.2MTMR3 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 22 GeneLoc Exon Structure GeneLoc location for GC22P030279: view genomic region
(about GC identifiers)
Start:
|
30,279,144 bp from pter |
End:
|
31,521,442 bp from pter |
Size:
|
1,242,299 bases |
Orientation:
|
plus strand |
|
Proteins
for MTMR3 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: MTMR3_HUMAN, Q13615 (See
protein sequence)Recommended Name: Myotubularin-related protein 3 Size: 1198 amino acids; 133619 Da
Subcellular location: Cytoplasm. Membrane; Peripheral membrane protein
Sequence caution: Sequence=BAA20826.2; Type=Erroneous initiation;
Secondary accessions: A5PL26 A7MD32 Q9NYN5 Q9NYN6 Q9UDX6 Q9UEG3Alternative splicing: 3 isoforms: Q13615-1 Q13615-2 Q13615-3 Explore the universe of human proteins at neXtProt for MTMR3: NX_Q13615
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q13615
4/7 DME Specific Peptides for MTMR3 (Q13615) (see all 7)
MTMR3 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_066576.1 NP_694690.1 NP_694691.1
ENSEMBL proteins: ENSP00000384651 ENSP00000409063 ENSP00000318070 ENSP00000307271 ENSP00000384077 ENSP00000331649 Reactome Protein details: Q13615
Human Recombinant Protein Products:
Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6): About this table
MTMR3 for ontologies About GeneDecksing
MTMR3 Antibody Products:
Assay Products for MTMR3: |
Protein
Domains /
Families
for MTMR3 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
MTMR3 for domains About GeneDecksing
5/7 InterPro domains/families (see all 7):Graphical View of Domain Structure for InterPro Entry Q13615ProtoNet protein and cluster: Q13615 2 Blocks protein families: IPB000306 Zn-finger IPB010569 Myotubularin-related
UniProtKB/Swiss-Prot: MTMR3_HUMAN, Q13615Similarity: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamilySimilarity: Contains 1 FYVE-type zinc fingerSimilarity: Contains 1 myotubularin phosphatase domain |
Function
for MTMR3 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: MTMR3_HUMAN, Q13615Function: Phosphatase that acts on lipids with a phosphoinositol headgroup. Has phosphatase activity towardsphosphatidylinositol 3-phosphate and phosphatidylinositol 3,5-bisphosphate. May also dephosphorylate proteinsphosphorylated on Ser, Thr, and Tyr residuesCatalytic activity: Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate Genatlas biochemistry entry for MTMR3:myotubularin related protein 3,expressed in skeletal muscle,heart,placenta,brain,liver and pancreas
Enzyme Number (IUBMB): EC 3.1.3.481 2
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MTMR3 (see all 6)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MTMR3 (see all 5)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): MTMR3 (NM_021090) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MTMR3 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MTMR3 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MTMR3 |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
MTMR3 for ontologies About GeneDecksing
3 GenomeRNAi human phenotypes for MTMR3:
Animal Models:
1 MGI mutant phenotype (inferred from 1 allele ) (MGI details for Mtmr3):
MTMR3 for phenotypes About GeneDecksing
|
Pathways & Interactions
for MTMR3 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/7 super-pathways (see all 7) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Metabolism | | | 2 | PI Metabolism | | | 3 | Phosphatases | | | 4 | D-myo-inositol-5-phosphate metabolism | | | 5 | Glycerophospholipid biosynthesis | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 
Cell Signaling Technology (CST) Pathway for MTMR3
3  BioSystems Pathways for MTMR3
5 
Reactome Pathways for MTMR3
MTMR3 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MTMR3
STRING Interaction
Network Preview (showing 5 interactants - click image to see 14)
5/16 Interacting proteins for MTMR3 (Q136153 ENSP000003846514) via UniProtKB, MINT, STRING, and/or I2D (see all 16)About this table
Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6): About this table
MTMR3 for ontologies About GeneDecksing
|
Drugs & Compounds
for MTMR3 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
MTMR3 for compounds About GeneDecksing
 Browse Tocris compounds for MTMR3
2 HMDB Compounds for MTMR3 About this table
2 Novoseek chemical compound relationships for MTMR3 gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| phosphatidylinositol 3-phosphate |
91.3 |
5 |
10900271 (1), 20188094 (1) |
| sodium orthovanadate |
72.2 |
1 |
11302699 (1) |
Search CenterWatch for drugs/clinical trials and news about MTMR3
|
Transcripts
for MTMR3 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for MTMR3 gene (4 alternative transcripts): NM_021090.3 NM_153050.2 NM_153051.2 NM_001013676.1 Unigene Cluster for MTMR3: Myotubularin related protein 3 Hs.474536 [show with all ESTs]Unigene Representative Sequence: NM_02109013 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000401950 ENST00000495098 ENST00000445401 ENST00000323630 ENST00000351488
ENST00000415511 ENST00000406629 ENST00000480776 ENST00000487907 ENST00000492087
ENST00000464734 ENST00000491251 ENST00000333027(uc003agu.4 uc003agv.4 uc003agw.4)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MTMR3 (see all 6)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MTMR3 (see all 5)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 3): MTMR3 (NM_021090) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MTMR3 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MTMR3 |
Additional cDNA sequence: AB002369.1 AF233436.2 AF233437.1 AF233438.1 AK056895.1 AK289581.1 BC142713.1 BC148216.1 BC151217.1 BC152455.1 CR456525.1 20 DOTS entries: DT.92436633 DT.117209 DT.445568 DT.100783326 DT.95205820 DT.97843870 DT.97765791 DT.91993302 DT.423228 DT.100783328 DT.40288631 DT.100783325 DT.101959245 DT.92000926 DT.95205818 DT.95300426 DT.40254946 DT.91836276 DT.91851590 DT.95337723 24/353 AceView cDNA sequences (see all 353): BF726258 BE673767 BF440002 AF233436 BE503878 AA658998 AL597523 BQ231958 BM974284 AA326426 BQ029405 AA973514 CR456525 AF233437 AI802137 AA253108 BQ718507 AI128208 BE670748 BQ182105 AA936077 BM707887 AL713498 AI797003
GeneLoc Exon Structure
5/9 Alternative Splicing Database (ASD) splice patterns (SP) for MTMR3 (see all 9) About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6a | · | 6b | ^ | 7a | · | 7b | · | 7c | ^ | 8a | · | 8b | ^ | 9a | · | 9b | ^ | 10a | · | 10b | ^ | 11a | · | 11b | ^ | 12 | ^ | 13 | ^ | 14a | · | 14b | ^ | 15 | ^ | 16a | · | 16b | ^ |
|---|
|
| SP1: | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 17a | · | 17b | · | 17c |
|---|
|
| SP1: | | | | | | | |
| SP2: | | | | | | | |
| SP3: | | | | | | | |
| SP4: | | | | | | | |
| SP5: | | | | | | |
ECgene alternative splicing isoforms for MTMR3
|
Expression
for MTMR3 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| MTMR3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AGGCTCAGAT
About this image
See MTMR3 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for MTMR3
SOURCE GeneReport for Unigene cluster: Hs.474536
SABiosciences Custom PCR Arrays for MTMR3
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MTMR3
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat MTMR3 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MTMR3 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MTMR3 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MTMR3 |
Orthologs
for MTMR3 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for MTMR3 gene from 7/23 species (see all 23) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
MTMR31 |
myotubularin related protein 3 |
76.19(n)
79.33(a) |
|
417015 XM_415304.3 XP_415304.3 |
African clawed frog
(Xenopus laevis) |
Amphibia |
Mtmr32 |
myotubularin-related protein 3 |
76.96(n) |
|
BC059312.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
BC062866.12 |
-- |
77.43(n) |
|
393838 BC062866.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG36321 , 3 |
protein amino acid dephosphorylation protein
tyrosine/serine/threonine more3
CG36321 |
48(a)3
46.5(n)1
39.67(a)1 |
|
325891 NM_001103526.21 NP_001096996.11 |
worm
(Caenorhabditis elegans) |
Secernentea |
T24A11.1b3 |
-- |
31(a)
(best of 2) |
|
III(3862632-3871844) -- |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
AT5G045406MTM16 |
Myotubularin-like phosphatases II-like protein |
24(a)22(a) |
many ↔ manymany ↔ many |
5(1296442-1302444) 3(3292899-3298522) |
rice
(Oryza sativa) |
Liliopsida |
-- |
inositol or phosphatidylinositol phosphatase/ phos... |
24(a) |
1 → many |
8(27856282-27865603) |
ENSEMBL Gene Tree for MTMR3 (if available)
TreeFam Gene Tree for MTMR3 (if available) |
Paralogs
for MTMR3 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for MTMR3 gene
- MTMR72 MTMR42 MTMR122 MTMR22 MTMR102 MTM12 MTMR82 MTMR92
- SBF22 MTMR62 MTMR112 SBF12 MTMR12
10 SIMAP similar genes for MTMR3 using alignment to 4 protein entries: MTMR3_HUMAN (see all proteins):MTMR4 MTMR10 MTM1 MTMR2 MTMR1 MTMR6
MTMR8 MTMR9 ZFYVE28 WUGSC
MTMR3 for paralogs About GeneDecksing
|
Genomic Variants
for MTMR3 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 22 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for MTMR3 (30279144 - 30529144 bp, first 250kb of MTMR3)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 4 variations for MTMR3
1 CNV: 73810
3 Indels: 79544 91023 67867 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MTMR3 |
|
Disorders
/ Diseases
for MTMR3 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
MTMR3 for disorders About GeneDecksing
OMIM gene information: 603558
OMIM disorders: --
9  diseases for MTMR3: About MalaCardscentronuclear myopathy inflammatory bowel disease myopathy crohn's disease
colon carcinoma lung carcinoma nephropathy carcinoma
neuronitis
1 disease from the University of Copenhagen DISEASES database for MTMR3:Centronuclear myopathy Human Genome Epidemiology (HuGE) Navigator: MTMR3 (1 document)
Export disorders for MTMR3 gene to outside databases
|
Publications
for MTMR3 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for MTMR3 gene, integrated from 9 sources (see all 37):
(articles sorted by number of sources associating them with MTMR3) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Characterization of the myotubularin dual specificity phosphatase gene family from yeast to human. (PubMed id 9736772)1, 2, 3 Laporte J....Mandel J.-L. (1998)
- A gene mutated in X-linked myotubular myopathy defines a new putative tyrosine phosphatase family conserved in yeast. (PubMed id 8640223)1, 2, 3 Laporte J.... Dahl N. (1996)
- FYVE-DSP1, a dual-specificity protein phosphatase containing an FYVE domain. (PubMed id 10733931)1, 2, 9 Zhao R.... Zhao Z.J. (2000)
- A genome annotation-driven approach to cloning the human ORFeome. (PubMed id 15461802)1, 2 Collins J.E.... Dunham I. (2004)
- Characterization of MTMR3. an inositol lipid 3-phosphatase with novel substrate specificity. (PubMed id 11676921)1, 2 Walker D.M.... Clague M.J. (2001)
- The DNA sequence of human chromosome 22. (PubMed id 10591208)1, 2 Dunham I....O'Brien K.P. (1999)
- Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9205841)1, 2 Nagase T.... Ohara O. (1997)
- FYVE-DSP2, a FYVE domain-containing dual specificity protein phosphatase that dephosphorylates phosphotidylinositol 3-phosphate. (PubMed id 11302699)1, 9 Zhao R.... Zhao Z.J. (2001)
- Modulation of local PtdIns3P levels by the PI phospha tase MTMR3 regulates constitutive autophagy. (PubMed id 20059746)1, 9 Taguchi-Atarashi N....Noda T. (2010)
- Inaugural article: myotubularin, a protein tyrosine phosphatase mutated in myotubular myopathy, dephosphorylates the lipid second messenger, phosphatidylinositol 3-phosphate. (PubMed id 10900271)1, 9 Taylor G.S....Dixon J.E. (2000)
|
External Searches for MTMR3 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing MTMR3 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing MTMR3 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing MTMR3 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for MTMR3 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for MTMR3 gene:
Search GeneIP for patents involving MTMR3
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for MTMR3 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for MTMR3 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MTMR3 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MTMR3 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for MTMR3 | | OriGene 3'-UTR Clone for MTMR3 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MTMR3 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MTMR3 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for MTMR3 | | OriGene Custom Protein Services for MTMR3 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MTMR3 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MTMR3 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MTMR3 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MTMR3 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MTMR3 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MTMR3 |
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| | Antibodies & Assays for MTMR3 |
| | | | Search Tocris compounds for MTMR3 |
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 | | | MTMR3 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MTMR3 |
|  |  |  | | | | Search ThermoFisher Antibodies for MTMR3 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MTMR3 |
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