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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

MTMR12 Gene

protein-coding   GIFtS: 53
GCID: GC05M032227

myotubularin related protein 12

(Previous name: phosphatidylinositol-3-phosphate associated protein )
(Previous symbol: PIP3AP)
 Explore 7 diseases affiliated with
MTMR12 via our new
 Human Malady Compendium 
Biological research products
for MTMR12
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Myotubularin Related Protein 121 2     3PAP1 5
3-PAP1 2 3     FLJ204761
PIP3AP1 2 3     3-Phosphatase Adapter Subunit2
KIAA16821 3 5     Myotubularin-Related Protein 122
Phosphatidylinositol-3-Phosphate Associated Protein1 2     Phosphatidylinositol-3 Phosphate 3-Phosphatase Adapter Subunit2
Phosphatidylinositol 3 Phosphate 3-Phosphatase Adapter Subunit2 3     Phosphatidylinositol-3 Phosphate 3-Phosphatase Adaptor Subunit2
3-Phosphatase Adapter Protein2 3     

External Ids:    HGNC: 181911   Entrez Gene: 545452   Ensembl: ENSG000001507127   OMIM: 6065015   UniProtKB: Q9C0I13   

Export aliases for MTMR12 gene to outside databases

Previous GC identifers: GC05M032263 GC05M032194


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for MTMR12:
Phosphatidylinositide 3-kinase-derived membrane-anchored phosphatidylinositides, such as phosphatidylinositol
3-phosphate (PtdIns(3)P), regulate diverse cellular processes. The protein encoded by this gene functions as an
adaptor subunit in a complex with an active PtdIns(3)P 3-phosphatase. Alternatively spliced transcript variants have
been identified, but their biological validity has not been determined. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: MTMRC_HUMAN, Q9C0I1
Function: Catalytically inactive phosphatase that plays a role as an adapter for the phosphatase myotubularin to
regulate myotubularin intracellular location




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000005.9  NC_018916.1  NT_006576.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the MTMR12 gene promoter:
         c-Fos   AP-1   FosB   HNF-1A   Max   AREB6   COMP1   HNF-1   c-Jun   c-Myc   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for MTMR12

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MTMR12


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5p13.3   Ensembl cytogenetic band:  5p13.3   HGNC cytogenetic band: 5p15.33

MTMR12 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MTMR12 gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05M032227:  view genomic region     (about GC identifiers)

Start:
32,227,100 bp from pter      End:
32,313,115 bp from pter
Size:
86,016 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: MTMRC_HUMAN, Q9C0I1 (See protein sequence)
Recommended Name: Myotubularin-related protein 12  
Size: 747 amino acids; 86148 Da
Subunit: Interacts with myotubularin MTM1 and myotubularin-related MTMR2
Subcellular location: Cytoplasm. Note=Localizes to punctate vesicles when associated with MTM1
Caution: Lacks the phosphocysteine intermediate Cys active site in position 391 that is replaced by a Glu residue,
preventing the hydrolase activity
Sequence caution: Sequence=BAB21773.1; Type=Erroneous initiation;
Secondary accessions: Q69YJ4 Q6PFW3 Q96QU2 Q9NX27
Alternative splicing: 3 isoforms:  Q9C0I1-1   Q9C0I1-2   Q9C0I1-3   

Explore the universe of human proteins at neXtProt for MTMR12: NX_Q9C0I1

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9C0I1

  • MTMR12 Protein expression data from MOPED and PaxDb:    About this image 
    MTMR12 Protein Expression
    REFSEQ proteins: NP_001035536.1  
    ENSEMBL proteins: 
     ENSP00000280285   ENSP00000371577   ENSP00000264934   ENSP00000426028   ENSP00000426912  

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    Uscn Proteins for MTMR12

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IEA--

    MTMR12 for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    MTMR12 for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR022587 Myotubularin_assoc
     IPR017906 Myotubularin_phosphatase_dom
     IPR011993 PH_like_dom

    Graphical View of Domain Structure for InterPro Entry Q9C0I1

    ProtoNet protein and cluster: Q9C0I1

    1 Blocks protein family: IPB010569 Myotubularin-related

    UniProtKB/Swiss-Prot: MTMRC_HUMAN, Q9C0I1
    Similarity: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily
    Similarity: Contains 1 myotubularin phosphatase domain


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: MTMRC_HUMAN, Q9C0I1
    Function: Catalytically inactive phosphatase that plays a role as an adapter for the phosphatase myotubularin to
    regulate myotubularin intracellular location

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016791phosphatase activity IEA--
         
    MTMR12 for ontologies           About GeneDecksing


    Phenotypes:
         3 GenomeRNAi human phenotypes for MTMR12:
     Decreased viability  Increased Salmonella enterica   Increased apoptosis 

    Animal Models:
       inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for MTMR12 

    miRNA
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    miRTarBase miRNAs that target MTMR12:
    hsa-mir-1 (MIRT003764)

    OriGene 3'-UTR Clone: MTMR12
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MTMR12
    8/96 QIAGEN miScript miRNA Assays for microRNAs that regulate MTMR12 (see all 96):
    hsa-miR-3938 hsa-miR-607 hsa-miR-520f hsa-miR-300 hsa-miR-200a hsa-miR-3653 hsa-miR-890 hsa-miR-29a*
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MTMR12


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MTMR12

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    4 Interacting proteins for MTMR12 (Q9C0I12, 3 ENSP000003715774) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MTMR2Q136142, 3, ENSP000003457524MINT-8217155 I2D: score=1 STRING: ENSP00000345752
    MTM1Q134962, 3, ENSP000003594234MINT-8216994 MINT-8217019 MINT-8217228 MINT-8217008 I2D: score=1 STRING: ENSP00000359423
    KBTBD7Q8WVZ93I2D: score=1 
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    MTMR12 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for MTMR12
    3 Novoseek chemical compound relationships for MTMR12 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    phosphatidylinositol 3-phosphate 92.3 5 11846405 (2), 11504939 (1), 1656463 (1)
    phosphatidylinositol 58.1 1 1656463 (1)
    lipid 28.2 2 11504939 (1), 12847286 (1)

    Search CenterWatch for drugs/clinical trials and news about MTMR12 / MTMRC 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for MTMR12 gene (2 alternative transcripts): 
    NM_001040446.1  NM_019061.2  

    Unigene Cluster for MTMR12:

    Myotubularin related protein 12
    Hs.481836  [show with all ESTs]
    Unigene Representative Sequence: NM_001040446
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000280285 ENST00000382142(uc003jhq.3 uc010iuk.3 uc010iul.3)
    ENST00000264934 ENST00000510216 ENST00000504049 ENST00000505419 ENST00000513622


    miRNA
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    OriGene 3'-UTR Clone: MTMR12
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MTMR12
    8/96 QIAGEN miScript miRNA Assays for microRNAs that regulate MTMR12 (see all 96):
    hsa-miR-3938 hsa-miR-607 hsa-miR-520f hsa-miR-300 hsa-miR-200a hsa-miR-3653 hsa-miR-890 hsa-miR-29a*
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    OriGene shRNA RFP: MTMR12
    OriGene siRNA: MTMR12
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MTMR12
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    Additional cDNA sequence: 

    AF085901.1 AK000483.1 AK000967.1 AL833231.1 AY028703.1 BC057393.1 

    7 DOTS entries:

    DT.86839464  DT.91819268  DT.100642802  DT.114764  DT.100778564  DT.91674264  DT.120840639 

    24/144 AceView cDNA sequences (see all 144):

    AI631808 AW517923 BG110634 AW673485 AF085901 AA427383 AK000483 AU117939 
    AA954508 CD251040 AW103743 NM_019061 AA810041 CD643788 BX099789 AA806806 
    H27970 AW473612 BQ017266 BM477473 BP357937 BQ011905 BG613924 AY028703 

    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for MTMR12 (see all 6)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9a · 9b ^ 10 ^ 11a · 11b ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18
    SP1:                          -                                         -                             -                                       
    SP2:                          -                                         -                             -                       -     -         
    SP3:                                                                                                                                          
    SP4:                                                                                                                                          
    SP5:                          -     -                                                                                                         


    ECgene alternative splicing isoforms for MTMR12

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    MTMR12 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: ACAATTTTTG
    MTMR12 Expression
    About this image
    See MTMR12 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for MTMR12

    SOURCE GeneReport for Unigene cluster: Hs.481836

    UniProtKB/Swiss-Prot: MTMRC_HUMAN, Q9C0I1
    Tissue specificity: Ubiquitous with prominent expression in brain, heart, kidney, placenta, and lung

        SABiosciences Custom PCR Arrays for MTMR12
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MTMR12

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for MTMR12 gene from 8/21 species (see all 21)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Mtmr121 , 5 myotubularin related protein 121, 5 87.18(n)1
    89.68(a)1
      15 (5.90 cM)5
    2687831  NM_172958.31  NP_766546.11 
     122050285 
    chicken
    (Gallus gallus)
    Aves MTMR121 myotubularin related protein 12 73.93(n)
    75.48(a)
      427423  XM_424996.3  XP_424996.3 
    lizard
    (Anolis carolinensis)
    Reptilia MTMR126
    --
    68(a)
    1 ↔ 1
    GL343335.1(194399-213995)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.174892 Transcribed sequence with weak similarity to protein more 76.81(n)    142013633 
    zebrafish
    (Danio rerio)
    Actinopterygii mtmr121 myotubularin related protein 12 59.18(n)
    53.95(a)
      569130  NM_001113613.1  NP_001107085.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG144116
    --
    21(a)
    1 → many
    X(14726671-14730295)
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons MTM16
    AT5G045406
    Myotubularin-like phosphatases II-like protein
    12(a)
    12(a)
    many ↔ many
    many ↔ many
    3(3292899-3298522)
    5(1296442-1302444)
    rice
    (Oryza sativa)
    Liliopsida --
    inositol or phosphatidylinositol phosphatase/ phos...
    13(a)
    1 → many
    8(27856282-27865603)


    ENSEMBL Gene Tree for MTMR12 (if available)
    TreeFam Gene Tree for MTMR12 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for MTMR12 gene
    MTMR42  MTMR72  MTMR22  MTMR102  MTM12  MTMR82  MTMR32  MTMR92  
    SBF22  MTMR62  MTMR112  SBF12  MTMR12  
    1 SIMAP similar gene for MTMR12 using alignment to 3 protein entries:     MTMRC_HUMAN (see all proteins):
    MTMR10

    MTMR12 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for MTMR12
    PGOHUM00000242876


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1481 NCBI SNPs in MTMR12 are shown (see all 1481    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 5 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs761378281,2
    F--32226676(+) TTTAGC/ATCCCA 1 -- ds50011Minor allele frequency- A:0.03EA 120
    rs1862734031,2
    --32226686(+) ACTTAC/TGAGAA 1 -- ds50010--------
    rs1154001621,2
    --32226762(+) ATGTTG/ACCGCA 1 -- ds50011Minor allele frequency- A:0.01NA 120
    rs1895315641,2
    C--32226885(+) TTGCTA/GTTGTG 1 -- ds50010--------
    rs18739231,2
    C,F,A--32226951(+) GTTATT/CGGTTC 1 -- ds50018Minor allele frequency- C:0.47WA NA CSA EA 366
    rs1385563041,2
    --32227071(+) TGAAAC/TGGATT 1 -- ds50010--------
    rs1814014461,2
    --32227104(+) CACCAA/GGTACA 1 -- ds50010--------
    rs1995636321,2
    C--32227249(+) TAAAG-/AAAAAA 1 -- ut310--------
    rs1865425111,2
    --32227462(+) AAATCA/CATTGA 1 -- ut310--------
    rs1905908871,2
    --32227476(+) TTCTGC/TACACA 1 -- ut310--------

    HapMap Linkage Disequilibrium report for MTMR12 (32227100 - 32313115 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 6 variations for MTMR12
         4 CNVs: 31229 3552 3551 8481
         2 Indels: 69045 33789
    Human Gene Mutation Database (HGMD): MTMR12

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    MTMR12 for disorders           About GeneDecksing

    OMIM gene information: 606501    OMIM disorders: --

    7 diseases for MTMR12:    About MalaCards
    cri-du-chat syndrome    cervix uteri carcinoma in situ    pelvic inflammatory disease    centronuclear myopathy
    gonorrhea    myopathy    carcinoma

    1 disease from the University of Copenhagen DISEASES database for MTMR12:
    Cri-Du-Chat syndrome
    Human Genome Epidemiology (HuGE) Navigator: MTMR12 (1 document)

    Export disorders for MTMR12 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for MTMR12 gene, integrated from 9 sources (see all 15):
    (articles sorted by number of sources associating them with MTMR12)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Characterization of an adapter subunit to a phosphatidylinositol (3)P 3-phosphatase: identification of a myotubularin-related protein lacking catalytic activity. (PubMed id 11504939)1, 2, 3, 9 Nandurkar H.H.... Mitchell C.A. (2001)
    2. Identification of myotubularin as the lipid phosphatase catalytic subunit associated with the 3-phosphatase adapter protein, 3-PAP. (PubMed id 12847286)1, 2, 9 Nandurkar H.H....Mitchell C.A. (2003)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. PTEN and myotubularin phosphatases: from 3-phosphoino sitide dephosphorylation to disease. (PubMed id 12495846)1, 3 Wishart M.J. and Dixon J.E. (2002)
    5. Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 11214970)1, 2 Nagase T.... Ohara O. (2000)
    6. Mutation screening of PDZD2, GOLPH3, and MTMR12 genes in patients with schizophrenia. (PubMed id 21451436)1 Ritter B.P....Bespalova I.N. (2012)
    7. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    8. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    9. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    10. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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    OMIM
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 54545 HGNC: 18191 AceView: PIP3AP Ensembl:ENSG00000150712 euGenes: HUgn54545
    ECgene: MTMR12 H-InvDB: MTMR12

    (According to HUGE)
    About This Section
    HUGE: KIAA1682

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for MTMR12 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for MTMR12 gene:
    Search GeneIP for patents involving MTMR12

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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