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Aliases for MTHFR Gene

Aliases for MTHFR Gene

  • Methylenetetrahydrofolate Reductase 2 3 5
  • EC 1.5.1.20 4 61
  • 5,10-Methylenetetrahydrofolate Reductase (NADPH) 2
  • Methylenetetrahydrofolate Reductase (NAD(P)H) 2

External Ids for MTHFR Gene

Previous GeneCards Identifiers for MTHFR Gene

  • GC01U990112
  • GC01M011694
  • GC01M011459
  • GC01M011556
  • GC01M011780
  • GC01M011000

Summaries for MTHFR Gene

Entrez Gene Summary for MTHFR Gene

  • The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.[provided by RefSeq, Oct 2009]

GeneCards Summary for MTHFR Gene

MTHFR (Methylenetetrahydrofolate Reductase) is a Protein Coding gene. Diseases associated with MTHFR include Homocystinuria Due To Mthfr Deficiency and Thrombophilia Due To Thrombin Defect. Among its related pathways are Folate-Alcohol and Cancer Pathway and Metabolism. GO annotations related to this gene include protein complex binding and NADP binding.

UniProtKB/Swiss-Prot for MTHFR Gene

  • Catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine.

Gene Wiki entry for MTHFR Gene

PharmGKB "VIP" Summary for MTHFR Gene

No data available for Tocris Summary , fRNAdb sequence ontologies and piRNA Summary for MTHFR Gene

Genomics for MTHFR Gene

Regulatory Elements for MTHFR Gene

Enhancers for MTHFR Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01F012166 1.6 FANTOM5 Ensembl ENCODE 22.3 -370.3 -370300 21.2 HDGF PKNOX1 CREB3L1 WRNIP1 ARID4B SIN3A YY1 ZNF143 ZNF207 FOS MTHFR TNFRSF1B UBIAD1 TNFRSF8 CLCN6 VPS13D DHRS3 AGTRAP MIIP MFN2
GH01F011943 0.2 ENCODE 20 -137.6 -137563 1.9 HDGF ATF1 PKNOX1 ARNT CREB3L1 FEZF1 GLI4 ZNF2 GLIS2 GATA2 ENSG00000226849 EXOSC10 MTHFR RNU5E-4P RNU5E-1 LOC102724659 PRAMEF30P LINC01784 PRAMEF4 HNRNPCL1
GH01F011784 1.3 Ensembl ENCODE 19.6 +18.3 18268 9.2 HDGF ARNT ZFP64 ARID4B ZNF2 YY1 SLC30A9 ZNF143 FOS KLF13 MTHFR NPPA-AS1 CLCN6 AGTRAP NPPB GC01M011790 PIR55960 LOC102724659
GH01F011800 0.2 ENCODE 14.3 +2.7 2692 8.3 HDGF PKNOX1 CREB3L1 MLX ARID4B SIN3A DMAP1 YY1 ZNF143 ZNF207 UBIAD1 CLCN6 EXOSC10 MTHFR NPPA-AS1 DHRS3 ENSG00000271895 ENSG00000226849 SNORA59A TNFRSF8
GH01F011795 0.5 ENCODE 12.3 +9.5 9524 4.6 HDGF PKNOX1 ARNT MLX CREB3L1 ZFP64 ARID4B SIN3A SLC30A9 ZNF766 CLCN6 NPPA-AS1 MTHFR AGTRAP NPPB ENSG00000271895 FBXO44 EXOSC10 GC01M011785
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MTHFR on UCSC Golden Path with GeneCards custom track

Promoters for MTHFR Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000161758 920 2401 HDGF PKNOX1 MLX ARID4B SIN3A DMAP1 YY1 ZNF143 ZNF207 FOS

Genomic Location for MTHFR Gene

Chromosome:
1
Start:
11,785,723 bp from pter
End:
11,806,920 bp from pter
Size:
21,198 bases
Orientation:
Minus strand

Genomic View for MTHFR Gene

Genes around MTHFR on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MTHFR Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MTHFR Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MTHFR Gene

Proteins for MTHFR Gene

  • Protein details for MTHFR Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P42898-MTHR_HUMAN
    Recommended name:
    Methylenetetrahydrofolate reductase
    Protein Accession:
    P42898
    Secondary Accessions:
    • B2R7A6
    • Q5SNW6
    • Q5SNW9
    • Q7Z6M6
    • Q8IU73
    • Q9UQR2

    Protein attributes for MTHFR Gene

    Size:
    656 amino acids
    Molecular mass:
    74597 Da
    Cofactor:
    Name=FAD; Xref=ChEBI:CHEBI:57692;
    Quaternary structure:
    • Homodimer.

    Alternative splice isoforms for MTHFR Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for MTHFR Gene

Post-translational modifications for MTHFR Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Antibody Products

  • Cloud-Clone Corp. Antibodies for MTHFR
  • Santa Cruz Biotechnology (SCBT) Antibodies for MTHFR

Domains & Families for MTHFR Gene

Graphical View of Domain Structure for InterPro Entry

P42898

UniProtKB/Swiss-Prot:

MTHR_HUMAN :
  • Belongs to the methylenetetrahydrofolate reductase family.
Family:
  • Belongs to the methylenetetrahydrofolate reductase family.
genes like me logo Genes that share domains with MTHFR: view

No data available for Gene Families for MTHFR Gene

Function for MTHFR Gene

Molecular function for MTHFR Gene

GENATLAS Biochemistry:
5-10 methylenetetrahydrofolate (THF) reductase,NADPH dependent,70kDa,reducing 5-10 methylene THF to,5 methyl-THF for methionine biosynthesis,with a common variant putatively involved in occlusive vascular disease,neural tube defects,colon cancer and adult akute leukemia. And a mutation responsible of increased mortality risk in men in middle and old age
UniProtKB/Swiss-Prot CatalyticActivity:
5-methyltetrahydrofolate + NAD(P)(+) = 5,10-methylenetetrahydrofolate + NAD(P)H.
UniProtKB/Swiss-Prot EnzymeRegulation:
Allosterically regulated by S-adenosylmethionine.
UniProtKB/Swiss-Prot Function:
Catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine.

Enzyme Numbers (IUBMB) for MTHFR Gene

Gene Ontology (GO) - Molecular Function for MTHFR Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003824 catalytic activity IEA --
GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity TAS --
GO:0016491 oxidoreductase activity IEA --
GO:0032403 protein complex binding IPI 24769206
GO:0050660 flavin adenine dinucleotide binding IDA 12673793
genes like me logo Genes that share ontologies with MTHFR: view
genes like me logo Genes that share phenotypes with MTHFR: view

Human Phenotype Ontology for MTHFR Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for MTHFR Gene

MGI Knock Outs for MTHFR:

Animal Model Products

Inhibitory RNA Products

Flow Cytometry Products

No data available for Transcription Factor Targets and HOMER Transcription for MTHFR Gene

Localization for MTHFR Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for MTHFR Gene COMPARTMENTS Subcellular localization image for MTHFR gene
Compartment Confidence
cytosol 5
nucleus 3
extracellular 2
mitochondrion 2
plasma membrane 2

Gene Ontology (GO) - Cellular Components for MTHFR Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005829 cytosol TAS --
GO:0045202 synapse IEA --
genes like me logo Genes that share ontologies with MTHFR: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for MTHFR Gene

Pathways & Interactions for MTHFR Gene

genes like me logo Genes that share pathways with MTHFR: view

UniProtKB/Swiss-Prot P42898-MTHR_HUMAN

  • Pathway: One-carbon metabolism; tetrahydrofolate interconversion.

Gene Ontology (GO) - Biological Process for MTHFR Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001666 response to hypoxia IEA --
GO:0006520 cellular amino acid metabolic process TAS 7647779
GO:0006555 methionine metabolic process IGI 10551815
GO:0008015 blood circulation TAS 7647779
GO:0008152 metabolic process IEA --
genes like me logo Genes that share ontologies with MTHFR: view

No data available for SIGNOR curated interactions for MTHFR Gene

Drugs & Compounds for MTHFR Gene

(86) Drugs for MTHFR Gene - From: DrugBank, PharmGKB, ClinicalTrials, HMDB, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Cyanocobalamin Approved Nutra Target, cofactor 249
Folic Acid Approved, Vet_approved Nutra Enzyme, substrate 4279
Benazepril Approved, Investigational Pharma Enzyme, substrate 45
Methotrexate Approved Pharma Enzyme, substrate Folate antagonist,inhibits DFHR 1518
Riboflavin Approved, Vet_approved Nutra Enzyme, cofactor 165

(39) Additional Compounds for MTHFR Gene - From: Novoseek and HMDB

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
5,10-Methylene-THF
  • (6R)-5,10-methylenetetrahydrofolate
  • 5,10-Methenyltetrahydropteroylglutamate
  • 5,10-Methylene-6-Hydrofolate
  • 5,10-Methylene-6-Hydrofolic acid
  • 5,10-Methylene-THF
31690-11-6
Hydrogen Ion
  • Hydrogen cation
  • Hydron
  • Proton
NADP
  • Adenine-nicotinamide dinucleotide phosphate
  • b-NADP
  • b-Nicotinamide adenine dinucleotide phosphate
  • b-TPN
  • beta-NADP
53-59-8
nadph
  • 2'-(Dihydrogen phosphate) 5'-(trihydrogen pyrophosphate) Adenosine 5'-ester with 1,4-dihydro-1-b-D-ribofuranosylnicotinamide
  • 2'-(Dihydrogen phosphate) 5'-(trihydrogen pyrophosphate) Adenosine 5'-ester with 1,4-dihydro-1-beta-delta-ribofuranosylnicotinamide
  • Adenosine 5'-(trihydrogen diphosphate) 2'-(dihydrogen phosphate) P'-5'-ester with 1,4-dihydro-1-beta-D-ribofuranosyl-3-pyridinecarboxamide
  • Adenosine 5'-(trihydrogen diphosphate) 2'-(dihydrogen phosphate) P'-5'-ester with 1,4-dihydro-1-beta-delta-ribofuranosyl-3-pyridinecarboxamide
  • b-NADPH
53-57-6
genes like me logo Genes that share compounds with MTHFR: view

Transcripts for MTHFR Gene

Unigene Clusters for MTHFR Gene

Methylenetetrahydrofolate reductase (NAD(P)H):
Representative Sequences:

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MTHFR Gene

ExUns: 1a · 1b · 1c · 1d · 1e ^ 2 ^ 3 ^ 4 ^ 5a · 5b · 5c ^ 6a · 6b · 6c · 6d · 6e · 6f ^ 7 ^ 8a · 8b ^ 9a · 9b ^ 10a · 10b ^ 11a · 11b ^
SP1: - - -
SP2: -
SP3: - - - - - - - -
SP4: - - - - - - -
SP5: - - - - -
SP6: - - - - - -
SP7: - -
SP8: - -
SP9:
SP10: - - - -
SP11: - - -

ExUns: 12 ^ 13 ^ 14 ^ 15a · 15b
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:
SP9:
SP10:
SP11:

Relevant External Links for MTHFR Gene

GeneLoc Exon Structure for
MTHFR
ECgene alternative splicing isoforms for
MTHFR

Expression for MTHFR Gene

mRNA expression in normal human tissues for MTHFR Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for MTHFR Gene

This gene is overexpressed in Peripheral blood mononuclear cells (17.7), Lymph node (15.8), and Stomach (6.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for MTHFR Gene



Protein tissue co-expression partners for MTHFR Gene

NURSA nuclear receptor signaling pathways regulating expression of MTHFR Gene:

MTHFR

SOURCE GeneReport for Unigene cluster for MTHFR Gene:

Hs.214142
genes like me logo Genes that share expression patterns with MTHFR: view

Primer Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for MTHFR Gene

Orthologs for MTHFR Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for MTHFR Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia MTHFR 34 35
  • 99.54 (n)
dog
(Canis familiaris)
Mammalia MTHFR 34 35
  • 88.74 (n)
cow
(Bos Taurus)
Mammalia MTHFR 34 35
  • 88.53 (n)
mouse
(Mus musculus)
Mammalia Mthfr 34 16 35
  • 86.78 (n)
oppossum
(Monodelphis domestica)
Mammalia MTHFR 35
  • 86 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia MTHFR 35
  • 86 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Mthfr 34
  • 85.68 (n)
chicken
(Gallus gallus)
Aves MTHFR 34 35
  • 78.64 (n)
lizard
(Anolis carolinensis)
Reptilia MTHFR 35
  • 71 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia mthfr 34
  • 71.71 (n)
Str.513 34
African clawed frog
(Xenopus laevis)
Amphibia mthfr-prov 34
zebrafish
(Danio rerio)
Actinopterygii mthfr 34 35
  • 73.9 (n)
fruit fly
(Drosophila melanogaster)
Insecta CG7560 35
  • 22 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea mthf-1 34 35
  • 53.28 (n)
A. gosspyii yeast
(Ashbya gossypii)
Saccharomycetes AGOS_AAR170W 34
  • 54.56 (n)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes MET13 34 35 37 37 37
  • 51.55 (n)
K. lactis yeast
(Kluyveromyces lactis)
Saccharomycetes KLLA0F09647g 34
  • 49.71 (n)
thale cress
(Arabidopsis thaliana)
eudicotyledons MTHFR1 34
  • 52.03 (n)
rice
(Oryza sativa)
Liliopsida Os03g0815200 34
  • 53.58 (n)
barley
(Hordeum vulgare)
Liliopsida Hv.1973 34
wheat
(Triticum aestivum)
Liliopsida Ta.1521 34
corn
(Zea mays)
Liliopsida Zm.475 34
sea squirt
(Ciona savignyi)
Ascidiacea CSA.2215 35
  • 60 (a)
OneToOne
bread mold
(Neurospora crassa)
Ascomycetes NCU07690 34
  • 55.06 (n)
fission yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes met9 34
  • 49.52 (n)
Species where no ortholog for MTHFR was found in the sources mined by GeneCards:
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)

Evolution for MTHFR Gene

ENSEMBL:
Gene Tree for MTHFR (if available)
TreeFam:
Gene Tree for MTHFR (if available)

Paralogs for MTHFR Gene

No data available for Paralogs for MTHFR Gene

Variants for MTHFR Gene

Polymorphic Variants from UniProtKB/Swiss-Prot for MTHFR Gene

MTHR_HUMAN-P42898
Genetic variation in MTHFR influences susceptibility to occlusive vascular disease, neural tube defects (NTD), colon cancer and acute leukemia.

Sequence variations from dbSNP and Humsavar for MTHFR Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs121434295 Methylenetetrahydrofolate reductase deficiency (MTHFRD) [MIM:236250], Pathogenic 11,801,166(-) GCTGC(A/G)GGGAG reference, missense
rs121434296 Methylenetetrahydrofolate reductase deficiency (MTHFRD) [MIM:236250], Pathogenic 11,794,766(-) TCTAC(C/T)GTACC reference, missense
rs121434297 Methylenetetrahydrofolate reductase deficiency (MTHFRD) [MIM:236250], Pathogenic 11,795,161(-) CACCC(C/T)CAACC reference, missense
rs138189536 Methylenetetrahydrofolate reductase deficiency (MTHFRD) [MIM:236250], Pathogenic 11,802,981(+) CTCCC(A/G)GAGTC reference, missense, utr-variant-5-prime
rs144508139 Methylenetetrahydrofolate reductase deficiency (MTHFRD) [MIM:236250] 11,791,244(+) CGGTG(A/G)GCTGG reference, missense

Structural Variations from Database of Genomic Variants (DGV) for MTHFR Gene

Variant ID Type Subtype PubMed ID
nsv518652 CNV loss 19592680

Variation tolerance for MTHFR Gene

Residual Variation Intolerance Score: 60% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 13.52; 95.55% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for MTHFR Gene

Human Gene Mutation Database (HGMD)
MTHFR
SNPedia medical, phenotypic, and genealogical associations of SNPs for
MTHFR

Disorders for MTHFR Gene

MalaCards: The human disease database

(140) MalaCards diseases for MTHFR Gene - From: OMIM, ClinVar, GeneTests, Orphanet, Swiss-Prot, DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
homocystinuria due to mthfr deficiency
  • homocystinuria due to deficiency of n -methylenetetrahydrofolate reductase activity
thrombophilia due to thrombin defect
  • thromboembolism
neural tube defects, folate-sensitive
  • neural tube defects
schizophrenia
  • schizophrenia 12
mthfr thermolabile variant
  • hyperhomocysteinemia
- elite association - COSMIC cancer census association via MalaCards
Search MTHFR in MalaCards View complete list of genes associated with diseases

UniProtKB/Swiss-Prot

MTHR_HUMAN
  • Ischemic stroke (ISCHSTR) [MIM:601367]: A stroke is an acute neurologic event leading to death of neural tissue of the brain and resulting in loss of motor, sensory and/or cognitive function. Ischemic strokes, resulting from vascular occlusion, is considered to be a highly complex disease consisting of a group of heterogeneous disorders with multiple genetic and environmental risk factors. {ECO:0000269 PubMed:15534175}. Note=Disease susceptibility is associated with variations affecting the gene represented in this entry.
  • Methylenetetrahydrofolate reductase deficiency (MTHFRD) [MIM:236250]: Autosomal recessive disorder with a wide range of features including homocysteinuria, homocysteinemia [MIM:603174], developmental delay, severe mental retardation, perinatal death, psychiatric disturbances, and later-onset neurodegenerative disorders. {ECO:0000269 PubMed:10679944, ECO:0000269 PubMed:20236116, ECO:0000269 PubMed:25736335, ECO:0000269 PubMed:7726158, ECO:0000269 PubMed:8940272, ECO:0000269 PubMed:9781030}. Note=The disease is caused by mutations affecting the gene represented in this entry.
  • Neural tube defects, folate-sensitive (NTDFS) [MIM:601634]: The most common NTDs are open spina bifida (myelomeningocele) and anencephaly. {ECO:0000269 PubMed:10323741, ECO:0000269 PubMed:7564788, ECO:0000269 PubMed:8826441}. Note=Disease susceptibility is associated with variations affecting the gene represented in this entry.

Relevant External Links for MTHFR

Genetic Association Database (GAD)
MTHFR
Human Genome Epidemiology (HuGE) Navigator
MTHFR
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MTHFR
genes like me logo Genes that share disorders with MTHFR: view

No data available for Genatlas for MTHFR Gene

Publications for MTHFR Gene

  1. A common haplotype on methylenetetrahydrofolate reductase gene modifies the effect of angiotensin-converting enzyme inhibitor on blood pressure in essential hypertension patients--a family-based association study. (PMID: 16081343) Jiang S. … Xu X. (Clin. Exp. Hypertens. 2005) 3 22 25 46 64
  2. Methylenetetrahydrofolate reductase genotype, vitamin B12, and folate influence plasma homocysteine in hemodialysis patients. (PMID: 11979347) Nakamura T. … Hata A. (Am. J. Kidney Dis. 2002) 3 22 25 46 64
  3. Polymorphisms in the methylenetetrahydrofolate reductase gene are associated with susceptibility to acute leukemia in adults. (PMID: 10536004) Skibola C.F. … Morgan G. (Proc. Natl. Acad. Sci. U.S.A. 1999) 3 4 22 46 64
  4. Human methylenetetrahydrofolate reductase: isolation of cDNA, mapping and mutation identification. (PMID: 7920641) Goyette P. … Rozen R. (Nat. Genet. 1994) 2 3 4 22 64
  5. Riboflavin lowers blood pressure in cardiovascular disease patients homozygous for the 677C-->T polymorphism in MTHFR. (PMID: 19952781) Horigan G. … Scott J.M. (J. Hypertens. 2010) 3 22 46 64

Products for MTHFR Gene

Sources for MTHFR Gene

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