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Aliases for MTFR1L Gene

Aliases for MTFR1L Gene

  • Mitochondrial Fission Regulator 1-Like 2 3
  • Family With Sequence Similarity 54, Member B 2 3
  • FAM54B 3 4
  • Protein FAM54B 3
  • HYST1888 3
  • MSTP116 3
  • MST116 3

External Ids for MTFR1L Gene

Previous Symbols for MTFR1L Gene

  • FAM54B

Summaries for MTFR1L Gene

GeneCards Summary for MTFR1L Gene

MTFR1L (Mitochondrial Fission Regulator 1-Like) is a Protein Coding gene. An important paralog of this gene is MTFR2.

Gene Wiki entry for MTFR1L Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MTFR1L Gene

Genomics for MTFR1L Gene

Genomic Location for MTFR1L Gene

Start:
25,818,640 bp from pter
End:
25,832,942 bp from pter
Size:
14,303 bases
Orientation:
Plus strand

Genomic View for MTFR1L Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MTFR1L Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MTFR1L Gene

No data available for Regulatory Elements for MTFR1L Gene

Proteins for MTFR1L Gene

  • Protein details for MTFR1L Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9H019-MFR1L_HUMAN
    Recommended name:
    Mitochondrial fission regulator 1-like
    Protein Accession:
    Q9H019
    Secondary Accessions:
    • A6NCB4
    • B7WNV5
    • D3DPJ4
    • Q63HP1
    • Q7Z2S7
    • Q9NUI7

    Protein attributes for MTFR1L Gene

    Size:
    292 amino acids
    Molecular mass:
    31957 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAQ13638.1; Type=Frameshift; Positions=7, 49; Evidence={ECO:0000305};

    Alternative splice isoforms for MTFR1L Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for MTFR1L Gene

Proteomics data for MTFR1L Gene at MOPED

Post-translational modifications for MTFR1L Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for MTFR1L Gene

Domains for MTFR1L Gene

Protein Domains for MTFR1L Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

MFR1L_HUMAN
Family:
  • Belongs to the MTFR1 family.:
    • Q9H019
genes like me logo Genes that share domains with MTFR1L: view

No data available for Gene Families for MTFR1L Gene

Function for MTFR1L Gene

Gene Ontology (GO) - Molecular Function for MTFR1L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with MTFR1L: view

Phenotypes for MTFR1L Gene

GenomeRNAi human phenotypes for MTFR1L:
genes like me logo Genes that share phenotypes with MTFR1L: view

miRNA for MTFR1L Gene

miRTarBase miRNAs that target MTFR1L

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for MTFR1L Gene

Localization for MTFR1L Gene

No data available for Gene Ontology (GO) - Cellular Components for MTFR1L Gene

Pathways for MTFR1L Gene

SuperPathways for MTFR1L Gene

No Data Available

Interacting Proteins for MTFR1L Gene

Gene Ontology (GO) - Biological Process for MTFR1L Gene

None

No data available for Pathways by source for MTFR1L Gene

Transcripts for MTFR1L Gene

Unigene Clusters for MTFR1L Gene

Mitochondrial fission regulator 1-like:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for MTFR1L Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b · 3c ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b · 8c ^ 9a · 9b · 9c ^ 10 ^ 11a · 11b · 11c ^ 12a · 12b ^ 13a · 13b ·
SP1: - - - - - - -
SP2: - - -
SP3: - - - - - - - -
SP4: - - - - - - - - -
SP5: - - - - - -
SP6: - - - - - - - - - - - - - - -
SP7: - - - - - - - -
SP8: - - - -
SP9: - -
SP10: - -
SP11: - -
SP12: - - - - - - - - - - -
SP13: - - - - - - - - - - - - -
SP14:

ExUns: 13c · 13d
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:
SP9:
SP10:
SP11:
SP12:
SP13:
SP14:

Relevant External Links for MTFR1L Gene

GeneLoc Exon Structure for
MTFR1L
ECgene alternative splicing isoforms for
MTFR1L

Expression for MTFR1L Gene

mRNA expression in normal human tissues for MTFR1L Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for MTFR1L Gene

SOURCE GeneReport for Unigene cluster for MTFR1L Gene Hs.149305

genes like me logo Genes that share expressions with MTFR1L: view

Orthologs for MTFR1L Gene

This gene was present in the common ancestor of chordates.

Orthologs for MTFR1L Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia FAM54B 36
  • 99.89 (n)
  • 100 (a)
FAM54B 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia MTFR1L 36
  • 93.54 (n)
  • 97.92 (a)
MTFR1L 37
  • 85 (a)
OneToOne
dog
(Canis familiaris)
Mammalia MTFR1L 36
  • 93.04 (n)
  • 98.63 (a)
MTFR1L 37
  • 99 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mtfr1l 36
  • 89.85 (n)
  • 95.85 (a)
Mtfr1l 16
Mtfr1l 37
  • 96 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia MTFR1L 37
  • 90 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia MTFR1L 37
  • 69 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Mtfr1l 36
  • 91.12 (n)
  • 95.85 (a)
chicken
(Gallus gallus)
Aves FAM54B 36
  • 73.5 (n)
  • 79.51 (a)
MTFR1L 37
  • 78 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia MTFR1L 37
  • 77 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia mtfr1l 36
  • 61.09 (n)
  • 58.91 (a)
zebrafish
(Danio rerio)
Actinopterygii mtfr1l 36
  • 60.17 (n)
  • 59.22 (a)
mtfr1l 37
  • 51 (a)
OneToOne
wufi39f11 36
Species with no ortholog for MTFR1L:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MTFR1L Gene

ENSEMBL:
Gene Tree for MTFR1L (if available)
TreeFam:
Gene Tree for MTFR1L (if available)

Paralogs for MTFR1L Gene

Paralogs for MTFR1L Gene

genes like me logo Genes that share paralogs with MTFR1L: view

Variants for MTFR1L Gene

Sequence variations from dbSNP and Humsavar for MTFR1L Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs1811819 -- 25,830,411(-) GTTCT(A/G)CTTTA intron-variant
rs1883161 -- 25,830,389(-) GTGTA(C/T)TTTTA intron-variant
rs2115804 -- 25,830,771(+) TTTGT(C/T)TCCTG intron-variant
rs4659384 -- 25,831,163(+) ACCAA(C/G)CAAAC intron-variant
rs6598923 -- 25,826,175(+) CCTTC(C/T)TCTGC intron-variant

Relevant External Links for MTFR1L Gene

HapMap Linkage Disequilibrium report
MTFR1L

No data available for Structural Variations from Database of Genomic Variants (DGV) for MTFR1L Gene

Disorders for MTFR1L Gene

No disorders were found for MTFR1L Gene.

No data available for UniProtKB/Swiss-Prot for MTFR1L Gene

Publications for MTFR1L Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. Expression profiling and differential screening between hepatoblastomas and the corresponding normal livers: identification of high expression of the PLK1 oncogene as a poor-prognostic indicator of hepatoblastomas. (PMID: 15221005) Yamada S. … Nakagawara A. (Oncogene 2004) 3 4
  3. Large-scale concatenation cDNA sequencing. (PMID: 9110174) Yu W. … Gibbs R.A. (Genome Res. 1997) 2 3
  4. A "double adaptor" method for improved shotgun library construction. (PMID: 8619474) Andersson B. … Gibbs R.A. (Anal. Biochem. 1996) 2 3
  5. Normalization and subtraction: two approaches to facilitate gene discovery. (PMID: 8889548) Bonaldo M.F. … Soares M.B. (Genome Res. 1996) 3

Products for MTFR1L Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate MTFR1L
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for MTFR1L
    • Block miRNA regulation of MTFR1L using miScript Target Protectors

    Sources for MTFR1L Gene

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