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MTCH2 Gene

protein-coding   GIFtS: 55
GCID: GC11M049909

Mitochondrial Carrier 2

(Previous name: mitochondrial carrier homolog 2 (C. elegans))
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Mitochondrial Carrier 21 2     Solute Carrier Family 251
Met-Induced Mitochondrial Protein2 3     2310034D24Rik2
MIMP2 3     SLC25A502
Member 501     Mitochondrial Carrier Homolog 22
Mitochondrial Carrier Homolog 2 (C. Elegans)1     Solute Carrier Family 25, Member 502

External Ids:    HGNC: 175871   Entrez Gene: 237882   Ensembl: ENSG000001099197   OMIM: 6132215   UniProtKB: Q9Y6C93   

Export aliases for MTCH2 gene to outside databases

Previous GC identifers: GC11U990208 GC11M048517 GC11M047670 GC11M047604 GC11M047600 GC11M047595 GC11M047639 GC11M047341 GC11M047745 GC11M048081 GC11M048804


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for MTCH2 Gene:
MTCH2 (mitochondrial carrier 2) is a protein-coding gene. An important paralog of this gene is MTCH1.

UniProtKB/Swiss-Prot: MTCH2_HUMAN, Q9Y6C9
Function: The substrate transported is not yet known. Induces mitochondrial depolarization

Gene Wiki entry for MTCH2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000011.9  NT_009237.19  NC_018922.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the MTCH2 gene promoter:
         NF-1   AML1a   Pax-2   MIF-1   Pax-2a   C/EBPalpha   MEF-2A   Pax-3   Pax-2b   HFH-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMTCH2 promoter sequence
   Search Chromatin IP Primers for MTCH2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MTCH2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11p11.2   Ensembl cytogenetic band:  11p11.2   HGNC cytogenetic band: 11p11.2

MTCH2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MTCH2 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11M049909:  view genomic region     (about GC identifiers)

Start:
47,638,858 bp from pter      End:
47,664,206 bp from pter
Size:
25,349 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: MTCH2_HUMAN, Q9Y6C9 (See protein sequence)
Recommended Name: Mitochondrial carrier homolog 2  
Size: 303 amino acids; 33331 Da
Secondary accessions: B2R7L8

Explore the universe of human proteins at neXtProt for MTCH2: NX_Q9Y6C9

Explore proteomics data for MTCH2 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys90, Lys100, Lys122, Lys293, Lys300
  • Modification sites at PhosphoSitePlus

  • See MTCH2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_055157.1  
    ENSEMBL proteins: 
     ENSP00000303222   ENSP00000432043   ENSP00000439013  

    MTCH2 Human Recombinant Protein Products:

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    Novus Biologicals MTCH2 Lysate
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    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for MTCH2

     
    Search eBioscience for Proteins for MTCH2 

     
    antibodies-online proteins for MTCH2 (2 products) 

     
    antibodies-online peptides for MTCH2

    MTCH2 Antibody Products:

    EMD Millipore Mono- and Polyclonal Antibodies for the study of MTCH2
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    antibodies-online antibodies for MTCH2 (38 products) 

    MTCH2 Assay Products:

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    Cloud-Clone Corp. ELISAs for MTCH2
    Cloud-Clone Corp. CLIAs for MTCH2
    Search eBioscience for ELISAs for MTCH2 
    antibodies-online kits for MTCH2 (3 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    SLC: Solute carriers

    2 InterPro protein domains:
     IPR023395 Mt_carrier_dom
     IPR018108 Mitochondrial_sb/sol_carrier

    Graphical View of Domain Structure for InterPro Entry Q9Y6C9

    ProtoNet protein and cluster: Q9Y6C9

    UniProtKB/Swiss-Prot: MTCH2_HUMAN, Q9Y6C9
    Similarity: Belongs to the mitochondrial carrier (TC 2.A.29) family
    Similarity: Contains 2 Solcar repeats


    Find genes that share domains with MTCH2           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: MTCH2_HUMAN, Q9Y6C9
    Function: The substrate transported is not yet known. Induces mitochondrial depolarization

    Phenotypes:
         1 MGI phenotypic allele for Mtch2 (no phenotypes)


    Find genes that share phenotypes with MTCH2           About GenesLikeMe

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for MTCH2

    miRNA
    Products:
        
    miRTarBase miRNAs that target MTCH2:
    hsa-let-7e-5p (MIRT051550), hsa-mir-26b-5p (MIRT029895), hsa-mir-423-5p (MIRT038156), hsa-mir-30c-5p (MIRT047945), hsa-mir-484 (MIRT042361)

    Block miRNA regulation of human, mouse, rat MTCH2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate MTCH2 (see all 46):
    hsa-miR-323-3p hsa-miR-579 hsa-miR-219-1-3p hsa-miR-520e hsa-miR-302d hsa-miR-105 hsa-miR-4314 hsa-miR-372
    SwitchGear 3'UTR luciferase reporter plasmidMTCH2 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for MTCH2
    Predesigned siRNA for gene silencing in human, mouse, rat MTCH2

    Gene Editing
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    GenScript: all cDNA clones in your preferred vector: MTCH2 (NM_014342)
    Sino Biological Human cDNA Clone for MTCH2
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MTCH2

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    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MTCH2


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    MTCH2_HUMAN, Q9Y6C9: Mitochondrion inner membrane; Multi-pass membrane protein (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    mitochondrion5
    extracellular2
    cytosol1
    lysosome1
    nucleus1
    peroxisome1
    plasma membrane1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion ----
    GO:0005743mitochondrial inner membrane IEA--
    GO:0016021integral component of membrane IEA--

    Find genes that share ontologies with MTCH2           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for MTCH2
    Interactions:

        Search GeneGlobe Interaction Network for MTCH2

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    4 Interacting proteins for MTCH2 (Q9Y6C93 ENSP000003032224) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UBCP0CG483, ENSP000003448184I2D: score=1 STRING: ENSP00000344818
    ESR1P033723I2D: score=2 
    YWHABP319463I2D: score=1 
    SUMO2ENSP000004059654STRING: ENSP00000405965
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006810transport IEA--

    Find genes that share ontologies with MTCH2           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for MTCH2



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for MTCH2 gene: 
    NM_014342.3  

    Unigene Cluster for MTCH2:

    Mitochondrial carrier 2
    Hs.269944  [show with all ESTs]
    Unigene Representative Sequence: NM_014342
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000539759 ENST00000302503(uc010rho.2 uc010rhp.2) ENST00000534074
    ENST00000525649 ENST00000530428 ENST00000533571 ENST00000542981
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat MTCH2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate MTCH2 (see all 46):
    hsa-miR-323-3p hsa-miR-579 hsa-miR-219-1-3p hsa-miR-520e hsa-miR-302d hsa-miR-105 hsa-miR-4314 hsa-miR-372
    SwitchGear 3'UTR luciferase reporter plasmidMTCH2 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for MTCH2
    Predesigned siRNA for gene silencing in human, mouse, rat MTCH2
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    GenScript: all cDNA clones in your preferred vector: MTCH2 (NM_014342)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MTCH2
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for MTCH2
    OriGene qSTAR qPCR primer pairs in human, mouse for MTCH2
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat MTCH2
      QuantiTect SYBR Green Assays in human, mouse, rat MTCH2
      QuantiFast Probe-based Assays in human, mouse, rat MTCH2

    Additional mRNA sequence: 

    AF085361.1 AF176008.1 AK223097.1 AK295218.1 AK313032.1 AY380792.1 BC000875.1 

    16 DOTS entries:

    DT.454735  DT.97862134  DT.100805067  DT.100833567  DT.100805069  DT.100805066  DT.92450572  DT.95099612 
    DT.95160519  DT.120745740  DT.92450569  DT.95160524  DT.100810427  DT.92471420  DT.95160523  DT.95202405 

    Selected AceView cDNA sequences (see all 420):

    BQ962596 AA505444 CR618611 AL047081 BU162682 CB144461 BC000875 BM695846 
    BM770934 BG255456 AI452396 AW511451 BG111172 AU280457 BM760118 AI207533 
    Z44944 BG250559 AF085361 AW162171 BU535539 W79341 AL546451 AI798270 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for MTCH2 (see all 6)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9a · 9b ^ 10 ^ 11 ^ 12 ^ 13
    SP1:                                                                                -                                 
    SP2:                                            -                                   -                                 
    SP3:                                            -                                   -                                 
    SP4:                    -                                                                                             
    SP5:                                                                                -                 -               


    ECgene alternative splicing isoforms for MTCH2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    MTCH2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGGAGCTCGG
    MTCH2 Expression
    About this image


    MTCH2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 7) fully expand
     
     Intermediate Mesoderm (Gastrulation Derivatives)
             Mesonephros
     
     Brain (Nervous System)
             Cerebellum
     
     Colon (Gastrointestinal Tract)
     
     Ovary (Reproductive System)
     
     Testis (Reproductive System)
    MTCH2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    MTCH2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.269944
        Custom PCR Arrays for MTCH2
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MTCH2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for MTCH2 gene from Selected species (see all 18)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Mtch21 , 5 mitochondrial carrier homolog 2 (C. elegans)1, 5 91.09(n)1
    93.73(a)1
      2 (50.41 cM)5
    564281  NM_019758.21  NP_062732.11 
     908471555 
    chicken
    (Gallus gallus)
    Aves MTCH21 mitochondrial carrier 2 70.41(n)
    80.27(a)
      395597  NM_204808.1  NP_990139.1 
    lizard
    (Anolis carolinensis)
    Reptilia MTCH26
    mitochondrial carrier 2
    75(a)
    1 ↔ 1
    1(94133800-94155901)
    African clawed frog
    (Xenopus laevis)
    Amphibia MGC645622 mitochondrial carrier homolog 2 72.88(n)    BC054302.1 
    zebrafish
    (Danio rerio)
    Actinopterygii mtch22 mitochondrial carrier homolog 2 73.67(n)   30655  BC055216.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Mtch1 , 3 carrier3
    Mitochondrial carrier homolog 11
    38(a)
    (best of 2)3
    46.64(n)1
    40.68(a)1
      61B23
    380261  NM_167799.31  NP_728481.11 
    worm
    (Caenorhabditis elegans)
    Secernentea mtch-11 mtch-1 43.35(n)
    30.74(a)
      174207  NM_063144.5  NP_495545.3 


    ENSEMBL Gene Tree for MTCH2 (if available)
    TreeFam Gene Tree for MTCH2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for MTCH2 gene
    MTCH12  
    2 SIMAP similar genes for MTCH2 using alignment to 3 protein entries:     MTCH2_HUMAN (see all proteins):
    PIG60    MTCH1

    Find genes that share paralogs with MTCH2           About GenesLikeMe


    5 Pseudogenes.org Pseudogenes for MTCH2
    PGOHUM00000239889 PGOHUM00000248894 PGOHUM00000259140 PGOHUM00000259141 PGOHUM00000237785


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for MTCH2 (see all 592)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1169564781,2
    F--47638453(+) ATGGTC/TTCGAA 1 -- ds50011Minor allele frequency- T:0.03NA 120
    rs1484550051,2
    --47638480(+) AACCAC/TCTGCC 1 -- ds50010--------
    rs1427356841,2
    --47638488(+) GCCTCA/GGCCTC 1 -- ds50010--------
    rs2016987691,2
    C--47638555(+) ATGGC-/ACCTAC 1 -- ds50010--------
    rs1465200401,2
    C--47638628(+) ATGGAA/GGATCA 1 -- ds50010--------
    rs1399472601,2
    --47638634(+) GATCAC/TAGGTA 1 -- ds50010--------
    rs1431891251,2
    --47638905(+) TTTTGG/TGAGAA 1 -- ut310--------
    rs1896804161,2
    --47638953(+) GCAGAC/TAGTAA 1 -- ut310--------
    rs120991301,2
    C,F,A,H--47639010(+) AGAGAC/AATCAA 1 -- ut3117Minor allele frequency- A:0.10NS EA NA WA 1896
    rs1823117031,2
    --47639030(+) AAGCCA/GAGCTC 1 -- ut310--------

    HapMap Linkage Disequilibrium report for MTCH2 (47638858 - 47664206 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10 variations for MTCH2:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2744440CNV Deletion23290073
    nsv509405CNV Insertion20534489
    esv995881CNV Insertion20482838
    esv1465053CNV Insertion17803354
    esv998557CNV Insertion20482838
    nsv69CNV Insertion15895083
    nsv315CNV Insertion18451855
    nsv832142CNV Loss17160897
    nsv469858CNV Gain16826518
    nsv825872CNV Gain20364138

    Human Gene Mutation Database (HGMD): MTCH2
    Site Specific Mutation Identification with PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers for resequencing MTCH2
    DNA2.0 Custom Variant and Variant Library Synthesis for MTCH2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 613221    OMIM disorders: --


    Find genes that share disorders with MTCH2           About GenesLikeMe

    Genetic Association Database (GAD): MTCH2
    Human Genome Epidemiology (HuGE) Navigator: MTCH2 (24 documents)

    Export disorders for MTCH2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for MTCH2 gene, integrated from 10 sources (see all 54):
    (articles sorted by number of sources associating them with MTCH2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Association between obesity and polymorphisms in SEC16B, TMEM18, GNPDA2, BDNF, FAIM2 and MC4R in a Japanese population. (PubMed id 19851340)1, 4, 9 Hotta K....Nakamura Y. (J. Hum. Genet. 2009)
    2. Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. (PubMed id 20935630)1, 4 Speliotes E.K....Loos R.J. (Nat. Genet. 2010)
    3. Genetic susceptibility to obesity and related traits in childhood and adolescence: influence of loci identified by genome-wide association studies. (PubMed id 20724581)1, 4 den Hoed M....Loos R.J. (Diabetes 2010)
    4. Evaluating the discriminative power of multi-trait genetic risk scores for type 2 diabetes in a northern Swedish population. (PubMed id 20571754)1, 4 Fontaine-Bisson B....Franks P.W. (Diabetologia 2010)
    5. Implication of genetic variants near NEGR1, SEC16B, TMEM18, ETV5/DGKG, GNPDA2, LIN7C/BDNF, MTCH2, BCDIN3D/FAIM2, SH2B1, FTO, MC4R, and KCTD15 with obesity and type 2 diabetes in 7705 Chinese. (PubMed id 20215397)1, 4 Ng M.C....Ma R.C. (J. Clin. Endocrinol. Metab. 2010)
    6. Are recently identified genetic variants regulating BMI in the general population associated with anorexia nervosa? (PubMed id 19746409)1, 4 Brandys M.K....Adan R.A. (Am. J. Med. Genet. B Neuropsychiatr. Genet. 2010)
    7. Analyses of shared genetic factors between asthma and obesity in children. (PubMed id 20816195)1, 4 MelAcn E....Lasky-Su J. (J. Allergy Clin. Immunol. 2010)
    8. Obesity and diabetes genetic variants associated with gestational weight gain. (PubMed id 20816152)1, 4 Stuebe A.M....Siega-Riz A.M. (Am. J. Obstet. Gynecol. 2010)
    9. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (PLoS ONE 2010)
    10. Obesity genotype score and cardiovascular risk in women with type 2 diabetes mellitus. (PubMed id 19910641)1, 4 He M....Qi L. (Arterioscler. Thromb. Vasc. Biol. 2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 23788 HGNC: 17587 AceView: MTCH2 Ensembl:ENSG00000109919 euGenes: HUgn23788
    ECgene: MTCH2 H-InvDB: MTCH2

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for MTCH2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for MTCH2 gene:
    Search GeneIP for patents involving MTCH2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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