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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

MTCH1 Gene

protein-coding   GIFtS: 50
GCID: GC06M036982

mitochondrial carrier 1

(Previous name: mitochondrial carrier homolog 1 (C. elegans) )
 Explore 1 disease affiliated with
MTCH1 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for MTCH1    

Aliases
for MTCH1 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Mitochondrial Carrier 11 2     Mitochondrial Carrier Homolog 1 (C. Elegans)1
PSAP1 2 3     PIG602
CGI-641 2     Cell Proliferation-Inducing Protein 602
SLC25A491 2     Mitochondrial Carrier Homolog 12
Presenilin-Associated Protein2 3     Solute Carrier Family 25, Member 492

External Ids:    HGNC: 175861   Entrez Gene: 237872   Ensembl: ENSG000001374097   OMIM: 6104495   UniProtKB: Q9NZJ73   

Export aliases for MTCH1 gene to outside databases

Previous GC identifers: GC06M036938 GC06M037043 GC06M036654


Summaries
for MTCH1 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for MTCH1:
This gene encodes a member of the mitochondrial carrier family. The encoded protein is localized to the mitochondrion
inner membrane and induces apoptosis independent of the proapoptotic proteins Bax and Bak. Pseudogenes on chromosomes
6 and 11 have been identified for this gene. Alternatively spliced transcript variants encoding multiple isoforms have
been observed. (provided by RefSeq, Oct 2012)

UniProtKB/Swiss-Prot: MTCH1_HUMAN, Q9NZJ7
Function: Potential mitochondrial transporter. May play a role in apoptosis

Gene Wiki entry for MTCH1


Genomic Views
for MTCH1 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NC_018917.1  NT_007592.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the MTCH1 gene promoter:
         Pax-5   MAZR   GCNF   CUTL1   LUN-1   CREB   IRF-2   GCNF-1   deltaCREB   GCNF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): MTCH1 promoter sequence
   Search SABiosciences Chromatin IP Primers for MTCH1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MTCH1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p21.2   Ensembl cytogenetic band:  6p21.2   HGNC cytogenetic band: 6p21.2

MTCH1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MTCH1 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06M036982:  view genomic region     (about GC identifiers)

Start:
 36,935,917 bp from pter      End:
 36,954,074 bp from pter
Size:
 18,158 bases      Orientation:
 minus strand

Proteins
for MTCH1 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: MTCH1_HUMAN, Q9NZJ7 (See protein sequence)
Recommended Name: Mitochondrial carrier homolog 1  
Size: 389 amino acids; 41544 Da
Subunit: Interacts with PSEN1
Subcellular location: Mitochondrion inner membrane; Multi-pass membrane protein (Potential)
Sequence caution: Sequence=AAF07936.1; Type=Erroneous initiation;
Secondary accessions: A8KAX5 B2RCE3 Q6PK60 Q6UX45 Q7L465 Q9BW23 Q9NZR6 Q9UJZ5
Alternative splicing: 3 isoforms:  Q9NZJ7-1   Q9NZJ7-2   Q9NZJ7-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for MTCH1: NX_Q9NZJ7

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9NZJ7

    • MTCH1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_001258570.1  NP_055156.1  

    ENSEMBL proteins: 
     ENSP00000362718   ENSP00000362730   ENSP00000362651   ENSP00000399187   ENSP00000419739  
     ENSP00000437660  

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    Novus Biologicals MTCH1 Protein
    Novus Biologicals MTCH1 Lysate
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    Browse ProSpec Recombinant Proteins
    Uscn Proteins for MTCH1

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular NAS10551805
    GO:0005739mitochondrion IMP12377771
    GO:0005743mitochondrial inner membrane IEA--
    GO:0016021integral to membrane IEA--


    MTCH1 for ontologies           About GeneDecksing



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    Protein Domains /
    Families
    for MTCH1 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    MTCH1 for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR023395 Mt_carrier_dom
     IPR018108 Mitochondrial_sb/sol_carrier

    Graphical View of Domain Structure for InterPro Entry Q9NZJ7

    ProtoNet protein and cluster: Q9NZJ7

    UniProtKB/Swiss-Prot: MTCH1_HUMAN, Q9NZJ7
    Similarity: Belongs to the mitochondrial carrier (TC 2.A.29) family
    Similarity: Contains 2 Solcar repeats


    Function
    for MTCH1 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: MTCH1_HUMAN, Q9NZJ7
    Function: Potential mitochondrial transporter. May play a role in apoptosis

    miRNA
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    hsa-miR-142-3p hsa-miR-520d-5p hsa-miR-4255 hsa-miR-524-5p hsa-miR-330-3p hsa-miR-580 hsa-miR-3652
    SwitchGear 3'UTR luciferase reporter plasmid: MTCH1 3' UTR sequence
    Inhib. RNA
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    Gene Editing
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    Search LifeMap BioReagents cell lines for MTCH1

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MTCH1

    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI10551805


    MTCH1 for ontologies           About GeneDecksing



    Pathways & Interactions
    for MTCH1 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for MTCH1

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    4 Interacting proteins for MTCH1 (Q9NZJ73 ENSP000003627184) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PSEN1P497683, ENSP000003263664I2D: score=2 STRING: ENSP00000326366
    SMAD2Q157963, ENSP000002621604I2D: score=2 STRING: ENSP00000262160
    YWHABP319463I2D: score=1 
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006810transport IEA--
    GO:0006919activation of cysteine-type endopeptidase activity involved in apoptotic process IMP12377771
    GO:0009966regulation of signal transduction NAS10551805
    GO:0043065positive regulation of apoptotic process IEP12377771
    GO:0045161neuronal ion channel clustering NAS10551805


    MTCH1 for ontologies           About GeneDecksing



    Drugs & Compounds
    for MTCH1 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for MTCH1
    Search CenterWatch for drugs/clinical trials and news about MTCH1 

    Transcripts
    for MTCH1 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for MTCH1 gene (2 alternative transcripts): 
    NM_001271641.1  NM_014341.2  

    Unigene Cluster for MTCH1:

    Mitochondrial carrier 1
    Hs.485262  [show with all ESTs]
    Unigene Representative Sequence: BC040659
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000490662 ENST00000373616(uc003onc.1 uc010jwo.1) ENST00000373627(uc003ond.1)
    ENST00000373550 ENST00000471737 ENST00000418541 ENST00000460219(uc003one.4 uc011dtt.2)
    ENST00000492754 ENST00000538808

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MTCH1
    7 QIAGEN miScript miRNA Assays for microRNAs that regulate MTCH1:
    hsa-miR-142-3p hsa-miR-520d-5p hsa-miR-4255 hsa-miR-524-5p hsa-miR-330-3p hsa-miR-580 hsa-miR-3652
    SwitchGear 3'UTR luciferase reporter plasmid: MTCH1 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MTCH1 (see all 7)
    OriGene shRNA RFP: MTCH1
    OriGene siRNA: MTCH1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MTCH1
    Clone
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    Primer
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    Additional cDNA sequence: 

    AF151822.1 AF176006.3 AF189289.1 AF192559.3 AK022783.1 AK130842.1 AK225628.1 AK303318.1 
    AK315067.1 AY358519.1 AY947344.1 BC000702.2 BC006507.2 BC009962.2 BC040659.1 BC110914.1 
    BC125055.1 BC125056.1 BC153873.1 

    24/35 DOTS entries (see all 35):

    DT.100039450  DT.320309  DT.100883871  DT.100023468  DT.100883870  DT.100883904  DT.91654661  DT.95141083 
    DT.100883893  DT.95141233  DT.100883884  DT.100039449  DT.100883891  DT.121371871  DT.100660960  DT.100883863 
    DT.100883876  DT.121316273  DT.92459747  DT.95141107  DT.95141205  DT.100651201  DT.100652777  DT.100692464 

    24/1022 AceView cDNA sequences (see all 1022):

    AA365970 CA306519 AI279557 AI339100 BM836672 CA396326 BQ880974 BQ672320 
    BU528925 BM013688 BQ919177 AW732241 CA394471 CF132117 BM811015 CR591303 
    AI350873 CR615322 CR601627 CR591948 AI610303 AA613417 BI861019 AA736839 

    GeneLoc Exon Structure

    5/12 Alternative Splicing Database (ASD) splice patterns (SP) for MTCH1 (see all 12)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5a · 5b · 5c ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10a · 10b · 10c · 10d ^ 11a · 11b ^ 12 ^ 13a · 13b ^ 14 ^ 15 ^ 16a ·
    SP1:              -           -                 -     -                       -                       -     -     -                       -     -     -         
    SP2:              -           -                 -     -     -                 -                       -     -     -                       -     -     -         
    SP3:              -           -                 -     -     -                 -                                   -                       -     -     -         
    SP4:              -           -                 -     -     -                 -                                   -                                             
    SP5:                          -                 -     -     -                 -                                                                                 

    ExUns: 16b · 16c
    SP1:            
    SP2:            
    SP3:            
    SP4:            
    SP5:            


    ECgene alternative splicing isoforms for MTCH1

    Expression
    for MTCH1 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    MTCH1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GTAAGATTTG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    MTCH1 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    4 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    BrainCerebral CortexBrain
    BrainChoroid PlexusBrain
    Neural TubeDiencephalic Roof PlateNeural Tube
    Neural TubeMetencephalonNeural Tube
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See MTCH1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for MTCH1

    SOURCE GeneReport for Unigene cluster: Hs.485262

    UniProtKB/Swiss-Prot: MTCH1_HUMAN, Q9NZJ7
    Tissue specificity: Widely expressed with a predominant expression in brain

        SABiosciences Expression via Pathway-Focused PCR Array including MTCH1: 
              Apoptosis 384HT in human mouse rat

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    In Situ
    Assay Products:     
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    Orthologs
    for MTCH1 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for MTCH1 gene from 5/17 species (see all 17)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Mtch11 , 5 mitochondrial carrier homolog 1 (C. elegans)1, 5 90.41(n)1
    98.12(a)1    		   17 (15.23 cM)5
    564621  NM_019880.31  NP_063933.11 
     293320725 
    chicken
    (Gallus gallus)    		 Aves MTCH11 mitochondrial carrier 1 74.81(n)
    77.17(a)    		   425491  XM_423245.3  XP_423245.2 
    African clawed frog
    (Xenopus laevis)    		 Amphibia Xl.208342 Xenopus laevis transcribed sequence 84.41(n)    BQ884392.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta Mtch3 carrier 36(a)   61B2   --
    worm
    (Caenorhabditis elegans)    		 Secernentea mtch-16
    		 Protein MTCH-1, isoform b
    		 24(a)
    		 1 → many
    		 II(7372553-7374131)


    ENSEMBL Gene Tree for MTCH1 (if available)
    TreeFam Gene Tree for MTCH1 (if available) 

    Paralogs
    for MTCH1 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for MTCH1 gene
    MTCH22  
    2 SIMAP similar genes for MTCH1 using alignment to 7 protein entries:     MTCH1_HUMAN (see all proteins):
    PIG60    MTCH2

    MTCH1 for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for MTCH1
    PGOHUM00000242184 PGOHUM00000243395


    Genomic Variants
    for MTCH1 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/425 NCBI SNPs in MTCH1 are shown (see all 425)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 6 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs122130051,2
    		C,H--36935432(+) CACCTC/TGAGCA 2 -- ds50014Minor allele frequency- T:0.00NS EA 420
    rs1128535181,2
    		C,--36935608(+) AGCTAC/GGTTAT 2 -- ds50013Minor allele frequency- G:0.03CSA WA 121
    rs1150806231,2
    		F,--36935611(+) TACGTT/CATCCT 2 -- ds50011Minor allele frequency- C:0.02WA 118
    rs777835261,2
    		C--36935762(+) ACTGAA/GCTACA 2 -- ds50010--------
    rs1933019751,2
    		--36935785(+) ACCTAC/TATCTC 2 -- ds50010--------
    rs789732051,2
    		--36935909(+) CCCCAC/TAAAAA 2 -- ds50011Minor allele frequency- T:0.01WA 118
    rs1855705561,2
    		--36936055(+) TACGCA/GAGGCA 2 -- ut310--------
    rs1904786821,2
    		--36936081(+) TGAGCA/GTTAGA 2 -- ut310--------
    rs115485821,2
    		C,F,H,--36936211(+) ATAGGC/TCTAGA 2 -- ut31 ese35Minor allele frequency- T:0.02NS NA 624
    rs1809307761,2
    		--36936253(+) CCCTAC/TGTACA 2 -- ut310--------

    HapMap Linkage Disequilibrium report for MTCH1 (36935917 - 36954074 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for MTCH1
         1 CNV: 69490

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    Disorders / Diseases
    for MTCH1 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    MTCH1 for disorders           About GeneDecksing

    OMIM gene information: 610449    OMIM disorders: --

    1 disease for MTCH1:    About MalaCards
    neuronitis

    Human Genome Epidemiology (HuGE) Navigator: MTCH1 (2 documents)

    Export disorders for MTCH1 gene to outside databases

    Publications
    for MTCH1 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for MTCH1 gene, integrated from 9 sources (see all 22):
    (articles sorted by number of sources associating them with MTCH1)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. The novel presenilin-1-associated protein is a proapoptotic mitochondrial protein. (PubMed id 12377771)1, 2, 3 Xu X.... Cui M.-Z. (2002)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (2003)
    5. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
    6. Identification of a novel PSD-95/Dlg/ZO-1 (PDZ)-like protein interacting with the C terminus of presenilin-1. (PubMed id 10551805)1, 2 Xu X.... Cui M.-Z. (1999)
    7. Two isoforms of PSAP/MTCH1 share two proapoptotic domains and multiple internal signals for import into the mitochondrial outer membrane. (PubMed id 17670888)1, 9 Lamarca V....Carrodeguas J.A. (2007)
    8. Both the N-terminal fragment and the protein-protein interaction domain (PDZ domain) are required for the pro-apoptotic activity of presenilin-associated protein PSAP. (PubMed id 18291114)1, 9 Mao G....Xu X. (2008)
    9. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    10. Global landscape of HIV-human protein complexes. (PubMed id 22190034)1 Jager S....Krogan N.J. (2012)

    External Searches for MTCH1 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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    Genome Databases showing MTCH1 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 23787 HGNC: 17586 AceView: MTCH1 Ensembl:ENSG00000137409 euGenes: HUgn23787
    ECgene: MTCH1 H-InvDB: MTCH1

    Other Databases showing MTCH1 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing MTCH1 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for MTCH1 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for MTCH1 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for MTCH1 gene:
    Search GeneIP for patents involving MTCH1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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