Aliases for MTBP Gene
External Ids for MTBP Gene
Previous GeneCards Identifiers for MTBP Gene
This gene encodes a protein that interacts with the oncoprotein mouse double minute 2. The encoded protein regulates progression through the cell cycle and may be involved in tumor formation. [provided by RefSeq, Aug 2012]
GeneCards Summary for MTBP Gene
MTBP (MDM2 Binding Protein) is a Protein Coding gene.
UniProtKB/Swiss-Prot for MTBP Gene
Inhibits cell migration in vitro and suppresses the invasive behavior of tumor cells (By similarity). May play a role in MDM2-dependent p53/TP53 homeostasis in unstressed cells. Inhibits autoubiquitination of MDM2, thereby enhancing MDM2 stability. This promotes MDM2-mediated ubiquitination of p53/TP53 and its subsequent degradation.