Aliases for MTA3 Gene
External Ids for MTA3 Gene
Previous GeneCards Identifiers for MTA3 Gene
GeneCards Summary for MTA3 Gene
MTA3 (Metastasis Associated 1 Family Member 3) is a Protein Coding gene. Diseases associated with MTA3 include Gastroesophageal Junction Adenocarcinoma. Among its related pathways are Chromatin organization and RNA Polymerase I Promoter Escape. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and chromatin binding. An important paralog of this gene is MTA1.
UniProtKB/Swiss-Prot for MTA3 Gene
Plays a role in maintenance of the normal epithelial architecture through the repression of SNAI1 transcription in a histone deacetylase-dependent manner, and thus the regulation of E-cadherin levels. Contributes to transcriptional repression by BCL6.