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MTA2 Gene

protein-coding GIFtS: 57

GC11M062119

metastasis associated 1 family, member 2
(Previous names: metastasis associated gene family, member 2 )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: MTA1L1)

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
DKFZp686F2281 ^²
MTA1-L1 ^¹
MTA1L1 ^², ³
PID ^², ³

Descriptions
MTA1-L1 protein ^³
Metastasis-associated 1-like 1 ^², ³
metastasis -associated gene 1-like 1 ^²
metastasis associated 1 family, member 2 ^²
metastasis associated gene family, member 2 ^¹, ²
metastasis-associated protein 2 ^²
p53 target protein in deacetylase complex ^³

External Ids
HGNC: 7411¹
Entrez Gene: 9219²
UniProtKB: O94776³
Ensembl: ENSG00000149480⁷

Search outside databases for aliases for MTA2 gene

Previous GC identifer: GC11M062136

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for MTA2:

This gene encodes a protein that has been identified as a component of NuRD, a nucleosome

remodeling deacetylase complex identified in the nucleus of human cells. It shows a very broad

expression pattern and is strongly expressed in many tissues. It may represent one member of a

small gene family that encode different but related proteins involved either directly or

indirectly in transcriptional regulation. Their indirect effects on transcriptional regulation may

include chromatin remodeling. It is closely related to another member of this family, a protein

that has been correlated with the metastatic potential of certain carcinomas. These two proteins

are so closely related that they share the same types of domains. These domains include two DNA

binding domains, a dimerization domain, and a domain commonly found in proteins that methylate

DNA. One of the proteins known to be a target protein for this gene product is p53. Deacteylation

of p53 is correlated with a loss of growth inhibition in transformed cells supporting a connection

between these gene family members and metastasis. [provided by RefSeq]

UniProtKB/Swiss-Prot: MTA2_HUMAN, O94776

Function: May be involved in the regulation of gene expression as repressor and activator. The

repression might be related to covalent modification of histone proteins

Gene Wiki entry for MTA2

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the MTA2 gene

Entrez Gene cytogenetic band: 11q12-q13.1 Ensembl cytogenetic band: 11q12.3 HGNC cytogenetic band: 11q12-q13.1

MTA2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 11 GeneLoc Exon Structure

GeneLoc location for GC11M062119: (about GC identifiers)

Start:	62,117,251 bp from pter
End:	62,125,879 bp from pter
Size:	8,629 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000011.8 NT_033903.7

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: MTA2_HUMAN, O94776 (See protein sequence)

Recommended Name: Metastasis-associated protein MTA2

Size: 668 amino acids; 75023 Da

Subunit: Component of the nucleosome-remodeling and histone-deacetylase multiprotein complex

(NuRD). Interacts with HDAC7, p53/TP53, MINT and MBD3 (By similarity)

Subcellular location: Nucleus (By similarity)

Sequence caution: Sequence=AAH23656.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence.

Potential poly-A sequence;

Secondary accessions: Q9UQB5

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_004730.2

ENSEMBL proteins:

ENSP00000278823

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (MTA2)
	Human Recombinant Proteins from Abnova (MTA2)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

4 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IEA	--
GO:0005730	NOT nucleolus	IDA	18029348
GO:0016581	NuRD complex	IEA	--
GO:0016585	chromatin remodeling complex	IEA	--

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Antibodies for MTA2:

	Browse Antibodies Central at Invitrogen
	Millipore Mono- and Polyclonal Antibodies for the study of MTA2
	Sigma-Aldrich Antibody Arrays and Antibodies for MTA2
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (MTA2), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (MTA2)
	Novus Biologicals Antibodies for MTA2

Assays for MTA2:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry O94776

ProtoNet protein and cluster: O94776

3 Blocks protein families:

IPB000679 Zn-finger

IPB000949 ELM2 domain

IPB001025 Bromo adjacent region

UniProtKB/Swiss-Prot: MTA2_HUMAN, O94776

Similarity: Contains 1 BAH domain

Similarity: Contains 1 ELM2 domain

Similarity: Contains 1 GATA-type zinc finger

Similarity: Contains 1 SANT domain

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (MTA2)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (MTA2)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_004739

Applied Biosystems Silencer® siRNAs for MTA2

Sigma-Aldrich siRNA for MTA2

Sigma-Aldrich shRNA for MTA2

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for MTA2
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_004739
Myc/DDK tagged cDNA clone in CMV expression vector: NM_004739
untagged cDNA clone in CMV expression vector: NM_004739

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_004739

UniProtKB/Swiss-Prot: MTA2_HUMAN, O94776

Function: May be involved in the regulation of gene expression as repressor and activator. The

repression might be related to covalent modification of histone proteins

12 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for Mta2):

craniofacial	growth/size	hematopoietic system	homeostasis/metabolism	immune system
lethality-prenatal/perinatal	life span-post-weaning/aging	liver/biliary system	renal/urinary system	reproductive system
skeleton	skin/coat/nails

5/8 Gene Ontology (GO) molecular function terms (links to tree view) (see all 8 ):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003700	transcription factor activity	IEA	--
GO:0004407	histone deacetylase activity	IEA	--
GO:0005515	protein binding	IEA	--
GO:0008270	zinc ion binding	IEA	--
GO:0016563	transcription activator activity	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

1 Sigma-Aldrich "Your Favorite Gene" Pathway for MTA2 (Your Favorite Gene powered by Ingenuity)

DNA Methylation and Transcriptional Repression Signaling

GeneDecks MTA2 for the pathways selected above

About GeneDecksing

Gene Network Central^TM Interacting Genes and Proteins Network for MTA2

5/31 Interacting proteins for MTA2 (ENSP00000278823³ O94776²) via UniProtKB, MINT, and/or STRING (see all 31 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
ESR1	P03372²	STRING (score=.798) MINT-6613980 MINT-6614421 MINT-6613885
HDAC1	Q13547²	STRING (score=.999) MINT-6613980 MINT-6613697 MINT-6613885
CHD3	Q12873²	STRING (score=.976) MINT-6613980 MINT-6613885
HDAC2	Q92769²	STRING (score=.999) MINT-6613697
MTA1	Q13330²	MINT-6613980 MINT-6613885

About this table

4 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	IEA	--
GO:0006333	chromatin assembly or disassembly	TAS	10444591
GO:0006355	regulation of transcription, DNA-dependent	IEA	--
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	IEA	--

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for MTA2

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (MTA2)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (MTA2)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_004739

Sigma-Aldrich siRNA for MTA2

Sigma-Aldrich shRNA for MTA2

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_004739

REFSEQ mRNAs for MTA2 gene:

NM_004739.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_004739

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_004739
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_004739
                                 untagged cDNA clone in CMV expression vector: NM_004739

Additional cDNA sequence:

AB016591.1 AF295807.1 AK301569.1 BC023656.2 BC053650.1 CR601321.1 CR749481.1

12 DOTS entries:

DT.40120984 DT.100816505 DT.100023584 DT.97861405 DT.120740843 DT.91748966 DT.100699305 DT.99975877

DT.120740817 DT.91748286 DT.91981747 DT.99930197

19 AceView cDNA sequences:

BM563145 BG765875 AL580744 CK819574 BM129842 BG765494 BM129583 BE148666

BM748993 BF921441 BX473072 BF933478 BQ354007 BF897932 BF990046 BI761567

AW605885 BM129316 AA861111

highest scoring ESTs for MTA2:

AB016591 AF295807 AL561056 AL580744 BC023656 BC053650 BG682762 BX340764 BX403752 BX406524

Unigene Cluster for MTA2:

Metastasis associated 1 family, member 2

Hs.173043 [show with all ESTs]

Unigene Representative Sequence: NM_004739

GeneLoc Exon Structure

5/9 Alternative Splicing Database (ASD) splice patterns (SP) for MTA2 (see all 9 )

ExUns:	1a	·	1b	^	2	^	3	^	4a	·	4b	^	5	^	6a	·	6b	·	6c	^	7	^	8a	·	8b	·	8c	^	9	^	10	^	11	^	12	^	13	^	14	^	15	^	16	^	17	^	18a	·	18b	^	19	^
SP1:
SP2:
SP3:					-				-										-
SP4:					-				-
SP5:									-

ExUns:	20a	·	20b	^	21
SP1:
SP2:
SP3:
SP4:
SP5:

About this scheme

ECgene alternative splicing isoforms for MTA2

1 Ensembl transcript including schematic representation:

ENST00000278823

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

MTA2 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for MTA2

¹ / ² / ³

2 probe-sets matching MTA2 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
203444_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_004739	0.60	0.83	0.73	1
203444_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: TGGGAACCTA

SOURCE GeneReport for Unigene cluster: Hs.173043
Expression variation in blood from EXPOLDB for MTA2
UniProtKB/Swiss-Prot: MTA2_HUMAN, O94776
Tissue specificity: Widely expressed

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for MTA2 gene from 5/8 species (see all 8 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	MTA2¹	--	metastasis associated 1 family, member 2	93.11(n) 98.95(a)	476057 XM_533265.2 XP_533265.2
chimpanzee (Pan troglodytes)	MTA2¹	--	metastasis associated 1 family, member 2	99.59(n) 99.85(a)	451255 XM_001152977.1 XP_001152977.1
cow (Bos taurus)	MTA2¹	--	metastasis associated 1 family, member 2	93.04(n) 98.65(a)	515389 NM_001075712.1 NP_001069180.1
rat (Rattus norvegicus)	Mta2¹	--	metastasis associated 1 family, member 2	90.52(n) 98.05(a)	361724 XM_342015.3 XP_342016.2
mouse (Mus musculus)	Mta2^{1, 5}	19⁵	metastasis-associated gene family, member 2^{1, 5}	91.17(n)¹ 98.5(a)¹	23942¹ NM_011842.3¹ NP_035972.3¹ AB047977⁵ AF159259⁵ (see all 55)

About this table Species with no ortholog for MTA2

ENSEMBL Gene Tree for MTA2

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for MTA2 gene

MTA3² MTA1²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/28 NCBI SNPs in MTA2 are shown (see all 28 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 32)

AB	SNP ID	Valid	Chr 11 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs1058678^1,2	C,F,H	62117613(-)	`taaaaA/GttttG`	1	--	ut3¹		8		MN EU EA WA NA	722
--	rs12226821^1,2	A	62125594(+)	`GGCTGC/GCGCTT`	1	--	ut5¹ ese³		0	--	--	--	--
	rs2849030^1,2	A,C,F,H	62123562(-)	`TTTTCT/CTTTTT`	1	--	int¹ trp³		4		EU EA WA	416
	rs2849031^1,2	A,C,F,H	62122241(-)	`CTCCCT/CGCCGC`	1	--	int¹ trp³		4		EU EA WA	412
	rs11231154^1,2	A,C,F,H	62118869(+)	`GTAATA/GCTGAA`	1	--	int¹		4		EU EA WA	418
	rs3750991^1,2	C,F,H	62120435(+)	`AGGGAG/AAATGT`	1	--	int¹		9		EA EU WA	2334
	rs2516634^1,2	A,C	62123762(-)	`TTGCGC/TTTTTT`	1	--	int¹		0	--	--	--	--
	rs11231155^1,2	A,C	62122195(+)	`CTGGAA/GTTGGG`	1	--	int¹		0	--	--	--	--
--	rs11231158^1,2	C	62124342(+)	`CAACGG/TAGCAG`	1	--	int¹		0	--	--	--	--
	rs12223627^1,2	A	62125133(+)	`CCCGCC/GGTGGC`	1	--	int¹		0	--	--	--	--

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HapMap Linkage Disequilibrium images for MTA2 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 603947

3 Novoseek disease relationships for MTA2 gene

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
breast cancer	33.27	1	16533771 (1)
metastasis	22.82	2	12920132 (1), 16533771 (1)
tumors	18.41	4	12920132 (1), 19116762 (1), 16533771 (1)

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(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/39 PubMed articles for MTA2 gene (see all 39 ):

Molecular cloning, mapping and characterization of a novel human gene, MTA1-L1. showing homology to a metastasis-associated gene, MTA1. (PubMed id 9929979)^{1, 2, 3, 4} Futamura M....Tokino T. (1999)
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)^{3, 4} Olsen J.V....Mann M. (2006)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
Sharp, an inducible cofactor that integrates nuclear receptor repression and activation. (PubMed id 11331609)^{3, 4} Shi Y....Evans R.M. (2001)
Deacetylation of p53 modulates its effect on cell growth and apoptosis. (PubMed id 11099047)^{3, 4} Luo J.... Gu W. (2000)
The metastasis-associated proteins 1 and 2 form distinct protein complexes with histone deacetylase activity. (PubMed id 12920132)^{1, 3} Yao Y.-L. and Yang W.-M. (2003)
The mCpG-binding domain of human MBD3 does not bind to mCpG but interacts with NuRD/Mi2 components HDAC1 and MTA2. (PubMed id 12124384)^{1, 3} Saito M. and Ishikawa F. (2002)
Molecular association between ATR and two components of the nucleosome remodeling and deacetylating complex, HDAC2 and CHD4. (PubMed id 10545197)^{1, 3} Schmidt D.R. and Schreiber S.L. (1999)
Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis. (PubMed id 18220336)⁴ Cantin G.T....Yates J.R. III (2008)
Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle. (PubMed id 18691976)⁴ Daub H.... Mann M. (2008)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 9219	HGNC: 7411	AceView: MTA2.1	Ensembl:ENSG00000149480	euGenes: HUgn9219
ECgene: MTA2	H-InvDB: MTA2

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
ATLAS Chromosomes in Cancer entry for MTA2	Genetics and Cytogenetics in Oncology and Haematology

Licensable Technologies for MTA2
(Available from WIS Yeda, Salk, Tufts)

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(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
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Products for MTA2:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for MTA2-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for MTA2		Antibodies for MTA2
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for MTA2		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

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	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

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MTA2 Gene

protein-coding GIFtS: 57

Aliases &
Descriptions
for MTA2

Summaries
for MTA2

Genomic Location
for MTA2

Proteins
for MTA2

Protein Domains/
Families
for MTA2

Gene Function
for MTA2

Pathways & Interactions
for MTA2

Drugs & Compounds
for MTA2

Transcripts
for MTA2

Expression
for MTA2

Orthologs
for MTA2

Paralogs
for MTA2

SNPs/Variants
for MTA2

Disorders & Mutations
for MTA2

Medical News
for MTA2

Publications
for MTA2

Search for MTA2

Genome Databases showing MTA2

Other Databases showing MTA2

Specialized Databases showing MTA2

Licensable Technologies
for MTA2

Services
for MTA2

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

MTA2 Gene

protein-coding GIFtS: 57

Aliases & Descriptionsfor MTA2

Summariesfor MTA2

Genomic Locationfor MTA2

Proteinsfor MTA2

Protein Domains/Familiesfor MTA2

Gene Functionfor MTA2

Pathways & Interactionsfor MTA2

Drugs & Compoundsfor MTA2

Transcriptsfor MTA2

Expression for MTA2

Orthologsfor MTA2

Paralogsfor MTA2

SNPs/Variantsfor MTA2

Disorders & Mutationsfor MTA2

Medical Newsfor MTA2

Publicationsfor MTA2

Search for MTA2

Genome Databases showing MTA2

Other Databases showing MTA2

Specialized Databases showing MTA2

Licensable Technologiesfor MTA2

Servicesfor MTA2

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for MTA2

Summaries
for MTA2

Genomic Location
for MTA2

Proteins
for MTA2

Protein Domains/
Families
for MTA2

Gene Function
for MTA2

Pathways & Interactions
for MTA2

Drugs & Compounds
for MTA2

Transcripts
for MTA2

Expression
for MTA2

Orthologs
for MTA2

Paralogs
for MTA2

SNPs/Variants
for MTA2

Disorders & Mutations
for MTA2

Medical News
for MTA2

Publications
for MTA2

Licensable Technologies
for MTA2

Services
for MTA2