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metallothionein 1J, pseudogene(Previous names: metallothionein 1N, pseudogene, metallothionein 1J )
(Previous symbols: MT1, MT1NP, MT1J)
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Aliases
for MT1JP gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA
Quality score for the ORGUL clustered with this gene is 3
| Aliases |
|---|
| Metallothionein 1J, Pseudogene1 2 | | MTB1 2 | | MT1J1 2 5 | | Metallothionein 1J1 | | MT11 2 | | Metallothionein 1N, Pseudogene1 | | MT1NP1 2 | | |
| External Ids: | HGNC: 74021 | Entrez Gene: 44982 | Ensembl: ENSG000002559867 | OMIM: 1563565 | | ORGUL members: | |
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| NONCODE:n382997 n382996 | |
Export aliases for MT1JP gene to outside databasesPrevious GC identifer: GC16P055228
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Summaries
for MT1JP gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for MT1JP gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000016.9 NC_018927.1 NT_010498.15
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for MT1JP
Other transcription factors
Search SABiosciences Chromatin IP Primers for MT1JP
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MT1JP |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 16q13 Ensembl cytogenetic band: 16q12.2 HGNC cytogenetic band: 16q13MT1JP Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 16 GeneLoc Exon Structure GeneLoc location for GC16P056669: view genomic region
(about GC identifiers)
Start:
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56,669,237 bp from pter |
End:
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56,670,998 bp from pter |
Size:
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1,762 bases |
Orientation:
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plus strand |
ORGUL member locations:
Legend (see complete legend)
56669650 56670324 56670998 chr16
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Proteins
for MT1JP gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
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UniProtKB: --
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Protein
Domains /
Families
for MT1JP gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| -- |
Function
for MT1JP gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
|
Pathways & Interactions
for MT1JP gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
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Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MT1JP
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Drugs & Compounds
for MT1JP gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for MT1JP
Search CenterWatch for drugs/clinical trials and news about MT1JP 
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Transcripts
for MT1JP gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
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Unigene Cluster for MT1JP: Metallothionein 1J, pseudogene Hs.736648 Unigene Representative Sequence: AF3489943 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000444023 ENST00000563395(uc002ejo.1) ENST00000564564(uc002ejp.1)
Additional cDNA sequence: AF348994.2 NR_036677.1 2 DOTS entries: DT.120684849 DT.219306 24/231 AceView cDNA sequences (see all 231): BQ433067 AW951992 BI439088 BE906482 CB851102 BU164116 AI459690 AU107621 BQ182739 BM887687 BM817906 BX102639 BM818033 BU730105 F28406 BX356856 AA323224 BQ050782 BX458790 AW043998 AI581831 BQ772005 AA343368 AJ705828
GeneLoc Exon Structure
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Expression
for MT1JP gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| MT1JP expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GGCTGAGCCA
About this image
SOURCE GeneReport for Unigene cluster: Hs.736648
SABiosciences Custom PCR Arrays for MT1JP
Primer
Products: |  | Browse OriGene genome-wide validated SYBR primer pairs
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat MT1JP | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MT1JP | | | Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MT1JP |
Orthologs
for MT1JP gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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ENSEMBL Gene Tree for MT1JP (if available)
TreeFam Gene Tree for MT1JP (if available) |
Paralogs
for MT1JP gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for MT1JP gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
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| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 16 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
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HapMap Linkage Disequilibrium report for MT1JP (56669237 - 56670998 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for MT1JP: -- | SABiosciences Cancer Mutation PCR Assays |
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Disorders
/ Diseases
for MT1JP gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
 MT1JP for disorders About MalaCards
MT1JP for disorders About GeneDecksing
OMIM gene information: 156356
OMIM disorders: --
Export disorders for MT1JP gene to outside databases
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Publications
for MT1JP gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
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PubMed articles for MT1JP gene integrated from 9 sources:
(articles sorted by number of sources associating them with MT1JP) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Characterisation of six additional human metallothionein genes. (PubMed id 8049263)1, 3, 9 Stennard F.A....West A.K. (1994)
- Human metallothionein genes: structure of the functional locus at 16q13. (PubMed id 2286373)1, 3 West A.K....Richards R.I. (1990)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Structure and expression of two human metallothionein-I isoform genes and a related pseudogene. (PubMed id 2581970)1 Schmidt C.J....Hamer D.H. (1985)
- Heavy metal and growth hormone pathways in metallothionein regulation in fish RTH-149 cell line. (PubMed id 19154796)9 Vergani L....Gallo G. (2009)
- Polymerase chain reaction amplification and functional characterization of sockeye salmon histone H3, metallothionein-B, and protamine promoters. (PubMed id 8180631)9 Chan W.K. and Devlin R.H. (1993)
- A nuclear factor binds to the metal regulatory elements of the mouse gene encoding metallothionein-I. (PubMed id 1870976)9 Labbe S....Seguin C. (1991)
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External Searches for MT1JP gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing MT1JP gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
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Other Databases showing MT1JP gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing MT1JP gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
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| Name | Description |
| PharmGKB entry for MT1JP | Pharmacogenomics, SNPs, Pathways |
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About This Section
| Patent Information for MT1JP gene:
Search GeneIP for patents involving MT1JP
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for MT1JP gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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|  | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MT1JP | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MT1JP | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MT1JP | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MT1JP | | | Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MT1JP | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MT1JP |
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 |  |  |  | |
| | | | Search Tocris compounds for MT1JP |
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 | | | MT1JP Proteins, Antibodies, CLIAs, and ELISAs |
| | | |  |  |  | | | | Search ThermoFisher Antibodies for MT1JP |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat MT1JP |
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Last full update: 19 Mar 2013 -
Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013
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