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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

MT1E Gene

protein-coding   GIFtS: 49
GCID: GC16P056659

metallothionein 1E


(Previous symbol: MT1)
 Explore 16 diseases affiliated with
MT1E via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for MT1E    

Aliases
for MT1E gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Metallothionein 1E1 2     Metallothionein 1E (Functional)2
MT11 2     Metallothionein D2
MTD1 2     Metallothionein-1E1
MT-1E2 3     Metallothionein-IE3
MT-IE2 3     Metallothionein-IE3

External Ids:    HGNC: 73971   Entrez Gene: 44932   Ensembl: ENSG000001697157   OMIM: 1563515   UniProtKB: P047323   

Export aliases for MT1E gene to outside databases

Previous GC identifers: GC16U990040 GC16M056702 GC16P056387 GC16P056429 GC16P056435 GC16P055216


Summaries
for MT1E gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
UniProtKB/Swiss-Prot: MT1E_HUMAN, P04732
Function: Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are
transcriptionally regulated by both heavy metals and glucocorticoids

Gene Wiki entry for MT1E


Genomic Views
for MT1E gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000016.9  NC_018927.1  NT_010498.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the MT1E gene promoter:
         GR   TBP   Sp1   TFIID   GR-beta   GR-alpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: MT1E promoter sequence
   Search SABiosciences Chromatin IP Primers for MT1E

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MT1E


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16q13   Ensembl cytogenetic band:  16q12.2   HGNC cytogenetic band: 16q13

MT1E Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MT1E gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16P056659:  view genomic region     (about GC identifiers)

Start:
 56,659,387 bp from pter      End:
 56,661,024 bp from pter
Size:
 1,638 bases      Orientation:
 plus strand

Proteins
for MT1E gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: MT1E_HUMAN, P04732 (See protein sequence)
Recommended Name: Metallothionein-1E  
Size: 61 amino acids; 6014 Da
Subunit: Monomer
Secondary accessions: A2RRF7 Q86YX4 Q8TD51
Alternative splicing: 2 isoforms:  P04732-1   P04732-2   

Explore the universe of human proteins at neXtProt for MT1E: NX_P04732

MT1E Protein expression data from MOPED and PaxDb:    About this image 

Estimated protein expression log10 (pmol).

REFSEQ proteins: NP_783316.2  
ENSEMBL proteins: 
 ENSP00000307706   ENSP00000457516   ENSP00000328137  

Human Recombinant Protein Products: 
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OriGene Purified Protein: MT1E
OriGene Protein Over-expression Lysate: MT1E
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Novus Biologicals MT1E Protein
Novus Biologicals MT1E Lysate
Browse Sino Biological Recombinant Proteins
Browse ProSpec Recombinant Proteins
Uscn Proteins for MT1E

Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005634nucleus IDA8619255
GO:0005737cytoplasm IDA8619255
GO:0048471perinuclear region of cytoplasm ISS--


MT1E for ontologies           About GeneDecksing



MT1E Antibody Products: 
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Novus Biologicals MT1E Antibody
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Uscn Antibodies for MT1E
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Assay Products for MT1E: 
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GenScript Custom Assay Services for MT1E
Browse Enzo Life Sciences for kits & assays
Uscn ELISAs and CLIAs for MT1E

Protein Domains /
Families
for MT1E gene

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section
MT1E for domains           About GeneDecksing

5 InterPro domains/families:
 IPR000006 Metalthion_vert
 IPR018064 Metalthion_vert_metal_BS
 IPR003019 Metalthion_sfam_euk
 IPR023587 Metalthion_dom_vert
 IPR017854 Metalthion_dom

Graphical View of Domain Structure for InterPro Entry P04732

ProtoNet protein and cluster: P04732

1 Blocks protein family: IPB002400 Growth factor cystine knot superfamily signature

UniProtKB/Swiss-Prot: MT1E_HUMAN, P04732
Domain: Class I metallothioneins contain 2 metal-binding domains: four divalent ions are chelated within cluster A of
the alpha domain and are coordinated via cysteinyl thiolate bridges to 11 cysteine ligands. Cluster B, the
corresponding region within the beta domain, can ligate three divalent ions to 9 cysteines
Similarity: Belongs to the metallothionein superfamily. Type 1 family


Function
for MT1E gene

(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section
Function Summary:

     UniProtKB/Swiss-Prot: MT1E_HUMAN, P04732
Function: Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are
transcriptionally regulated by both heavy metals and glucocorticoids

     Genatlas biochemistry entry for MT1E:
metallothionein 1E cluster

miRNA
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QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MT1E
Search QIAGEN for miScript miRNA Assays for microRNAs that regulate MT1E
Browse SwitchGear 3'UTR luciferase reporter plasmids
Inhib. RNA
Products:    		Browse for Gene Knock-down Tools from EMD Millipore
OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MT1E
OriGene shRNA RFP: MT1E
OriGene siRNA: MT1E
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MT1E

Gene Editing
Products:		DNA2.0 Custom Protein Engineering Service for MT1E

Clone
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OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MT1E
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DNA2.0 Custom Codon Optimized Gene Synthesis Service for MT1E
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MT1E 

Cell Line
Products:     		GenScript Custom overexpressing Cell Line Services for MT1E
Search LifeMap BioReagents cell lines for MT1E

In Situ Assay
Products:   
 		Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for MT1E

Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005507copper ion binding NAS--
GO:0008270zinc ion binding NAS--
GO:0046870cadmium ion binding NAS--
GO:0046872metal ion binding ----


MT1E for ontologies           About GeneDecksing



Pathways & Interactions
for MT1E gene

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways  About this table 
See pathways by source

Super-pathwaycontained gene-specific pathways
1Mineral absorption
Mineral absorption1.00

Pathway sources
See GeneCards unified pathways
Show all pathways



1         Kegg Pathway  (Kegg details for MT1E):
    Mineral absorption


MT1E for pathways           About GeneDecksing

Interactions:

    SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for MT1E

Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0045926negative regulation of growth ISS--
GO:0071276cellular response to cadmium ion IEP16827180
GO:0071294cellular response to zinc ion IEP8119276


MT1E for ontologies           About GeneDecksing



Drugs & Compounds
for MT1E gene

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

MT1E for compounds           About GeneDecksing

Browse Small Molecules at EMD Millipore
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for MT1E

1 HMDB Compound for MT1E    About this table
CompoundSynonyms CAS #PubMed Ids
CadmiumCd (see all 6)7440-43-9--
5 Novoseek chemical compound relationships for MT1E gene    About this table
Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
cadmium 64.6 3 18755257 (1), 8171441 (1), 15952643 (1)
glyceraldehyde 3-phosphate 43 2 9831543 (1), 9422519 (1)
zinc 38.7 23 19083439 (3), 17468938 (1), 10774930 (1)
estrogen 29.1 18 9422519 (6), 10940647 (3), 19420986 (2), 14578200 (1) (see all 5)
copper 16.9 2 9831543 (1), 10940647 (1)

Search CenterWatch for drugs/clinical trials and news about MT1E 

Transcripts
for MT1E gene

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section
REFSEQ mRNAs for MT1E gene: 
NM_175617.3  

Unigene Cluster for MT1E:

Metallothionein 1E
Hs.534330  [show with all ESTs]
Unigene Representative Sequence: BU535774
3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000306061(uc002ejl.3) ENST00000568293 ENST00000330439(uc002ejm.3)


miRNA
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QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MT1E
Search QIAGEN for miScript miRNA Assays for microRNAs that regulate MT1E
Browse SwitchGear 3'UTR luciferase reporter plasmids
Inhib. RNA
Products:     		Browse for Gene Knock-down Tools from EMD Millipore
OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MT1E
OriGene shRNA RFP: MT1E
OriGene siRNA: MT1E
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MT1E
Clone
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GenScript: all cDNA clones in your preferred vector: MT1E (NM_175617)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for MT1E
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MT1E 
Primer
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Browse OriGene validated miRNA SYBR primer pairs
SABiosciences RT2 qPCR Primer Assay in human, mouse, rat MT1E
  QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MT1E
  QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MT1E

Additional cDNA sequence: 

BC009699.2 BC062734.1 BC131609.1 

16 DOTS entries:

DT.219306  DT.218152  DT.95236153  DT.100800149  DT.101982092  DT.95167555  DT.219307  DT.120684829 
DT.120684801  DT.95167556  DT.91961039  DT.121416733  DT.100839246  DT.120684912  DT.91808924  DT.95071762 

24/231 AceView cDNA sequences (see all 231):

BX458790 AW043998 NM_005954 BU176013 BX281399 AU107621 BI439088 AW055185 
BG180522 BM887687 AW951992 AJ705828 AJ573411 BQ181442 BQ050782 AJ709369 
BQ433067 BQ430119 BM817906 CR595825 AJ713317 D28442 CR621046 AW026555 

GeneLoc Exon Structure


Expression
for MT1E gene

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

MT1E expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --

Microarray
RNAseq (Illumina Body Map)
(100×FPKM)½
SAGE (Serial Analysis of Gene Expression)
About this image

MT1E expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
Stem Cell Differentiation: 2 LifeMap Cells 
NameCategory
PureStem™ progenitor EN2 (Embryonic Progenitor Cell)
Matrigel embedded cells (Derivation of cardio...)
Expression: Positive    Negative     Selective marker
Experimental details: Curated     Microarrays     In-situ hybridization

See MT1E Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for MT1E

SOURCE GeneReport for Unigene cluster: Hs.534330
    SABiosciences Custom PCR Arrays for MT1E
Primer
Products:		Browse OriGene genome-wide validated SYBR primer pairs
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QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MT1E
In Situ
Assay Products: 
 		Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for MT1E

Orthologs
for MT1E gene

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section
This gene was present in the common ancestor of chordates.

Orthologs for MT1E gene from 2/9 species (see all 9)    About this table
Organism Taxonomic
classification		 Gene Description Human
Similarity		 Orthology
Type		 Details
lizard
(Anolis carolinensis)		 Reptilia MT36
 --
 76(a)
 1 → many
 GL343675.1(182526-186438)
zebrafish
(Danio rerio)		 Actinopterygii mt26
 metallothionein 2
 67(a)
 1 → many
 18(17193795-17195147)


ENSEMBL Gene Tree for MT1E (if available)
TreeFam Gene Tree for MT1E (if available) 

Paralogs
for MT1E gene

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
Paralogs for MT1E gene
MT1G2  MT1X2  MT1F2  MT1B2  MT2A2  MT42  MT1M2  MT1A2  
MT32  MT1H2  
14 SIMAP similar genes for MT1E using alignment to 2 protein entries:     MT1E_HUMAN (see all proteins):
MT1H    MT1J    MTE    MT1X    MT1G    MT1F
MT1M    MT1A    MT1L    MT4    MT3    MT1B
MTP    MT2A

MT1E for paralogs           About GeneDecksing


2 Pseudogenes.org Pseudogenes for MT1E
PGOHUM00000249143 PGOHUM00000259531


Genomic Variants
for MT1E gene

(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

10/117 NCBI SNPs in MT1E are shown (see all 117)     About this table
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance		Chr 16 posSequence#AA
Chg		TypeMore#Allele
freq		PopTotal
sample		More
----------
rs1912893721,2
--56657613(+) ATTAGC/TTATTG 1 -- us2k10--------
rs1449095311,2
--56657619(+) ATTGC-/TTTTTT 1 -- us2k10--------
rs80618191,2
C,F,--56657627(+) TTTTTA/TAAAAA 1 -- us2k1 tfbs33Minor allele frequency- T:0.33NA 6
rs1121675131,2
--56657733(+) CACATG/AAACAT 1 -- us2k11Minor allele frequency- A:0.50CSA 2
rs1386893351,2
--56657748(+) CATGTA/GGTCCA 1 -- us2k10--------
rs1117207821,2
--56657761(+) GAGAGC/TCATTC 1 -- us2k11Minor allele frequency- T:0.50CSA 2
rs1878348551,2
--56657793(+) TCAACA/CCAGGG 1 -- us2k10--------
rs1474192701,2
--56657810(+) AGCTAC/TGAGCA 1 -- us2k10--------
rs1144101151,2
F,--56657934(+) GAAAAG/CCAAAC 1 -- us2k11Minor allele frequency- C:0.02WA 118
rs1921856711,2
--56657966(+) AAAATC/TGGTCC 1 -- us2k10--------

HapMap Linkage Disequilibrium report for MT1E (56659387 - 56661024 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
      Database of Genomic Variants (DGV) variations for MT1E: --

SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MT1E
DNA2.0 Custom Variant and Variant Library Synthesis for MT1E

Disorders / Diseases
for MT1E gene

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section
MT1E for disorders           About GeneDecksing

OMIM gene information: 156351    OMIM disorders: --

16 diseases for MT1E:    About MalaCards
type 2 diabetes mellitus    amyotrophic lateral sclerosis    lateral sclerosis    diabetes mellitus
acute lymphoblastic leukemia    lymphoblastic leukemia    renal cell carcinoma    endometrial carcinoma
prostate cancer    breast cancer    nasopharyngitis    pancreatic cancer
leukemia    prostatitis    pancreatitis    carcinoma

5 Novoseek disease relationships for MT1E gene    About this table

Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
breast cancer 33.8 15 10940647 (3), 10917545 (3), 11291768 (2), 9422519 (2) (see all 7)
bladder cancer 29.5 3 11270423 (2), 18724390 (1)
prostate cancer 24.4 1 10754528 (1)
tumors 17.8 5 18724390 (2), 15188022 (1), 18755257 (1)
cancer 0 5 19420986 (2), 18724390 (2)

Human Genome Epidemiology (HuGE) Navigator: MT1E (1 document)

Export disorders for MT1E gene to outside databases

Publications
for MT1E gene

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
About This Section

PubMed articles for MT1E gene, integrated from 9 sources (see all 60):
(articles sorted by number of sources associating them with MT1E)		    Utopia: connect your pdf to the dynamic
world of online information

  1. Structure and expression of two human metallothionein-I isoform genes and a related pseudogene. (PubMed id 2581970)1, 2, 3 Schmidt C.J....Hamer D.H. (1985)
  2. Induction by zinc of specific metallothionein isoforms in human monocytes. (PubMed id 8119276)1, 2, 9 Pauwels M.... Ley M. (1994)
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
  4. Human metallothionein genes are clustered on chromosome 16. (PubMed id 6089206)1, 3 Karin M....Shows T.B. (1984)
  5. Epigenetic alteration of the metallothionein 1E gene in human endometrial carcinomas. (PubMed id 19420986)1, 9 Tse K.Y....Ngan H.Y. (2009)
  6. Overlapping gene expression profiles of cell migration and tumor invasion in human bladder cancer identify metallothionein 1E and nicotinamide N-methyltransferase as novel regulators of cell migration. (PubMed id 18724390)1, 9 Wu Y....Theodorescu D. (2008)
  7. Metallothionein isoform gene expression in zinc-treated human peripheral blood lymphocytes. (PubMed id 10774930)1, 9 Vandeghinste N....De Ley M. (2000)
  8. Isoform-specific expression of metallothionein mRNA in the developing and adult human kidney. (PubMed id 8619255)1, 9 Mididoddi S....Sens D.A. (1996)
  9. Metallothionein 1 isoform gene expression induced by cadmium in human peripheral blood lymphocytes. (PubMed id 16827180)1, 9 Chang X.L....Zhou Y.F. (2006)
  10. Metallothionein isoform 1 and 2 gene expression in a human urothelial cell line (UROtsa) exposed to CdCl2 and NaAsO2. (PubMed id 14555400)1, 9 Sens D....Somji S. (2003)

External Searches for MT1E gene

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section
 ANDOR
Aliases
Disorders
Free Text  
  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

Genome Databases showing MT1E gene

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section
Entrez Gene: 4493 HGNC: 7397 AceView: MT2_ Ensembl:ENSG00000169715 euGenes: HUgn4493
ECgene: MT1E Kegg: 4493 H-InvDB: MT1E

Other Databases showing MT1E gene

(According to HUGE)
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Specialized Databases showing MT1E gene

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for MT1E Pharmacogenomics, SNPs, Pathways

Intellectual Property
for MT1E gene

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for MT1E gene:
Search GeneIP for patents involving MT1E

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



Products
for MT1E gene

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
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 QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MT1E
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 Regulatory tfbs in MT1E promoter
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 Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MT1E
       
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