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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

MT1E Gene

protein-coding   GIFtS: 50
GCID: GC16P056659

Metallothionein 1E


(Previous symbol: MT1)
Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Metallothionein 1E1 2     Metallothionein 1E (Functional)2
MT11 2     Metallothionein D2
MT-1E2 3     metallothionein-1E2
MT-IE2 3     metallothionein-IE2
MTD2     Metallothionein-IE3

External Ids:    HGNC: 73971   Entrez Gene: 44932   Ensembl: ENSG000001697157   OMIM: 1563515   UniProtKB: P047323   

Export aliases for MT1E gene to outside databases

Previous GC identifers: GC16U990040 GC16M056702 GC16P056387 GC16P056429 GC16P056435 GC16P055216


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for MT1E Gene: 
MT1E (metallothionein 1E) is a protein-coding gene. Diseases associated with MT1E include nasopharyngitis, and acute lymphoblastic leukemia. GO annotations related to this gene include cadmium ion binding and copper ion binding. An important paralog of this gene is MT1G.

UniProtKB/Swiss-Prot: MT1E_HUMAN, P04732
Function: Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins
are transcriptionally regulated by both heavy metals and glucocorticoids

Gene Wiki entry for MT1E Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000016.9  NT_010498.15  NC_018927.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the MT1E gene promoter:
         GR   TBP   Sp1   TFIID   GR-beta   GR-alpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMT1E promoter sequence
   Search SABiosciences Chromatin IP Primers for MT1E

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MT1E


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16q13   Ensembl cytogenetic band:  16q12.2   HGNC cytogenetic band: 16q13

MT1E Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MT1E gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16P056659:  view genomic region     (about GC identifiers)

Start:
56,659,387 bp from pter      End:
56,661,024 bp from pter
Size:
1,638 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: MT1E_HUMAN, P04732 (See protein sequence)
Recommended Name: Metallothionein-1E  
Size: 61 amino acids; 6014 Da
Subunit: Monomer
Secondary accessions: A2RRF7 Q86YX4 Q8TD51
Alternative splicing: 2 isoforms:  P04732-1   P04732-2   

Explore the universe of human proteins at neXtProt for MT1E: NX_P04732

Explore proteomics data for MT1E at MOPED 

MT1E Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

MT1E Protein Expression

REFSEQ proteins: NP_783316.2  
ENSEMBL proteins: 
 ENSP00000307706   ENSP00000457516   ENSP00000328137  

Human Recombinant Protein Products for MT1E: 
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Cloud-Clone Corp. Proteins for MT1E 

Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005634nucleus IDA8619255
GO:0005737cytoplasm IDA8619255
GO:0048471perinuclear region of cytoplasm ISS--

MT1E for ontologies           About GeneDecksing



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Cloud-Clone Corp. ELISAs for MT1E 
Cloud-Clone Corp. CLIAs for MT1E


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section
HGNC Gene Families: 
MT: Metallothioneins

5 InterPro protein domains:
 IPR000006 Metalthion_vert
 IPR018064 Metalthion_vert_metal_BS
 IPR003019 Metalthion_sfam_euk
 IPR023587 Metalthion_dom_vert
 IPR017854 Metalthion_dom

Graphical View of Domain Structure for InterPro Entry P04732

ProtoNet protein and cluster: P04732

1 Blocks protein domain: IPB002400 Growth factor cystine knot superfamily signature

UniProtKB/Swiss-Prot: MT1E_HUMAN, P04732
Domain: Class I metallothioneins contain 2 metal-binding domains: four divalent ions are chelated within cluster A
of the alpha domain and are coordinated via cysteinyl thiolate bridges to 11 cysteine ligands. Cluster B, the
corresponding region within the beta domain, can ligate three divalent ions to 9 cysteines
Similarity: Belongs to the metallothionein superfamily. Type 1 family


MT1E for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
About This Section

Molecular Function:

     UniProtKB/Swiss-Prot Summary: MT1E_HUMAN, P04732
Function: Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins
are transcriptionally regulated by both heavy metals and glucocorticoids

     Genatlas biochemistry entry for MT1E:
metallothionein 1E cluster

     Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005507copper ion binding NAS--
GO:0008270zinc ion binding NAS--
GO:0046870cadmium ion binding NAS--
GO:0046872metal ion binding ----
     
MT1E for ontologies           About GeneDecksing


Animal Models:
   inGenious Targeting Laboratory - Custom generated mouse model solutions for MT1E 
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   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for MT1E 
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for MT1E 

miRNA
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In Situ Assay
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MT1E


(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section

SuperPaths for MT1E About                                                                                                See pathways by source

SuperPathContained pathways About
1Mineral absorption
Mineral absorption

Pathways by source                                                                                                                                                                 See SuperPaths
Show all pathways



1         Kegg Pathway  (Kegg details for MT1E):
    Mineral absorption


MT1E for pathways           About GeneDecksing

Interactions:

    SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for MT1E

Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0045926negative regulation of growth ISS--
GO:0071276cellular response to cadmium ion IEP16827180
GO:0071294cellular response to zinc ion IEP11168427

MT1E for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

MT1E for compounds           About GeneDecksing

Browse Small Molecules at EMD Millipore
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for MT1E

1 HMDB Compound for MT1E    About this table
CompoundSynonyms CAS #PubMed Ids
CadmiumCd (see all 6)7440-43-9--

5 Novoseek inferred chemical compound relationships for MT1E gene    About this table
Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
cadmium 64.6 3 18755257 (1), 8171441 (1), 15952643 (1)
glyceraldehyde 3-phosphate 43 2 9831543 (1), 9422519 (1)
zinc 38.7 23 19083439 (3), 17468938 (1), 10774930 (1)
estrogen 29.1 18 9422519 (6), 10940647 (3), 19420986 (2), 14578200 (1) (see all 5)
copper 16.9 2 9831543 (1), 10940647 (1)

Search CenterWatch for drugs/clinical trials and news about MT1E

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for MT1E gene: 
NM_175617.3  

Unigene Cluster for MT1E:

Metallothionein 1E
Hs.744893  [show with all ESTs]
Unigene Representative Sequence: BU535774
3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000306061(uc002ejl.3) ENST00000568293 ENST00000330439(uc002ejm.3)

Congresses - knowledge worth sharing:  
European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

miRNA
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Inhib. RNA
Products:
     
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QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MT1E
Clone
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Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MT1E
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                     Customized lentivirus expression plasmids for stable overexpression of MT1E 
Primer
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  QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MT1E

Additional mRNA sequence: 

BC009699.2 BC062734.1 BC131609.1 

15 DOTS entries:

DT.219306  DT.95236153  DT.100800149  DT.218152  DT.101982092  DT.95167555  DT.219307  DT.120684801 
DT.95167556  DT.120684829  DT.91961039  DT.121416733  DT.100839246  DT.120684912  DT.91808924 

24/231 AceView cDNA sequences (see all 231):

BQ433067 AI581831 AI418147 AW055185 AW026555 AU107621 AI799708 AA374803 
AJ705828 AJ709369 BQ014486 CA446192 BQ182739 BC035624 AA343368 BX281399 
BM547245 AA323224 F27839 BQ225213 BX356856 AJ709390 AI129861 BE048260 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

MT1E expression in normal human tissues (normalized intensities)      MT1E embryonic expression: see
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: --
MT1E Expression
About this image


MT1E expression in embryonic tissues and stem cells    About this table
Data from LifeMap, the Embryonic Development and Stem Cells Database 
 5/4 selected tissues (see all 4) fully expand
 
 Endothelium (Cardiovascular System)
         Peripheral blood endothelial colony-forming cells
 
 Uncategorized (Uncategorized)
         PureStem Progenitor ES-139
 
 Liver (Hepatobiliary System)
 
 Spleen (Hematopoietic System)

See MT1E Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for MT1E

SOURCE GeneReport for Unigene cluster: Hs.744893
    SABiosciences Custom PCR Arrays for MT1E
Primer
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In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MT1E

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for MT1E gene from 2/8 species (see all 8)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Mt11 metallothionein 1 85.79(n)
85.25(a)
  17748  NM_013602.3  NP_038630.1 
zebrafish
(Danio rerio)
Actinopterygii mt26
metallothionein 2
63(a)
1 → many
18(17193795-17195147)


ENSEMBL Gene Tree for MT1E (if available)
TreeFam Gene Tree for MT1E (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
Paralogs for MT1E gene
MT1G2  MT1F2  MT1X2  MT1B2  MT2A2  MT1HL12  MT1M2  MT1H2  
MT1A2  
15 SIMAP similar genes for MT1E using alignment to 2 protein entries:     MT1E_HUMAN (see all proteins):
MT1H    MT1J    MT1X    MTE    MT1G    MT1F
MT1M    MT1A    MT1L    MT4    MT3    MT1B
MT1HL1    MTP    MT2A

MT1E for paralogs           About GeneDecksing


2 Pseudogenes.org Pseudogenes for MT1E
PGOHUM00000249143 PGOHUM00000259531


(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

10/151 SNPs in MT1E are shown (see all 151)    About this table     
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 16 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs1912893721,2
--56657613(+) ATTAGC/TTATTG 1 -- us2k10--------
rs1449095311,2
C--56657619(+) ATTGC-/TTTTTT 1 -- us2k10--------
rs80618191,2
C,F--56657627(+) tttttA/Taaaaa 1 -- us2k1 tfbs33Minor allele frequency- T:0.33NA 6
rs1121675131,2
F--56657733(+) CACATG/AAACAT 1 -- us2k11Minor allele frequency- A:0.50CSA 2
rs1386893351,2
--56657748(+) CATGTA/GGTCCA 1 -- us2k10--------
rs1117207821,2
F--56657761(+) GAGAGC/TCATTC 1 -- us2k11Minor allele frequency- T:0.50CSA 2
rs1878348551,2
--56657793(+) TCAACA/CCAGGG 1 -- us2k10--------
rs1474192701,2
C--56657810(+) AGCTAC/TGAGCA 1 -- us2k10--------
rs1144101151,2
F--56657934(+) GAAAAG/CCAAAC 1 -- us2k11Minor allele frequency- C:0.02WA 118
rs1921856711,2
C--56657966(+) AAAATC/TGGTCC 1 -- us2k10--------

HapMap Linkage Disequilibrium report for MT1E (56659387 - 56661024 bp)

Structural Variations
     Database of Genomic Variants (DGV) 1 variation for MT1E:    About this table     
Variant IDTypeSubtypePubMed ID
nsv906720CNV Loss21882294

SABiosciences Cancer Mutation PCR Assays
SeqTarget long-range PCR primers for resequencing MT1E
DNA2.0 Custom Variant and Variant Library Synthesis for MT1E

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section
OMIM gene information: 156351    OMIM disorders: --

14 diseases for MT1E:    About MalaCards
nasopharyngitis    acute lymphoblastic leukemia    endometrial carcinoma    lateral sclerosis
amyotrophic lateral sclerosis    lymphoblastic leukemia    renal cell carcinoma    diabetes mellitus
prostate cancer    pancreatic cancer    breast cancer    prostatitis
pancreatitis    leukemia


MT1E for disorders           About GeneDecksing

5 Novoseek inferred disease relationships for MT1E gene    About this table

Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
breast cancer 33.8 15 10940647 (3), 10917545 (3), 11291768 (2), 9422519 (2) (see all 7)
bladder cancer 29.5 3 11270423 (2), 18724390 (1)
prostate cancer 24.4 1 10754528 (1)
tumors 17.8 5 18724390 (2), 15188022 (1), 18755257 (1)
cancer 0 5 19420986 (2), 18724390 (2)

Genetic Association Database (GAD): MT1E
Human Genome Epidemiology (HuGE) Navigator: MT1E (1 document)

Export disorders for MT1E gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
About This Section

PubMed articles for MT1E gene, integrated from 9 sources (see all 61):
(articles sorted by number of sources associating them with MT1E)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Structure and expression of two human metallothionein-I isoform genes and a related pseudogene. (PubMed id 2581970)1, 2, 3 Schmidt C.J....Hamer D.H. (1985)
  2. Induction by zinc of specific metallothionein isoforms in human monocytes. (PubMed id 8119276)1, 2, 9 Pauwels M.... Ley M. (1994)
  3. Polymorphisms in metallothionein-1 and -2 genes associated with the risk of type 2 diabetes mellitus and its complications. (PubMed id 18349110)1, 4 Yang L....Liu Y. (2008)
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
  5. Human metallothionein genes are clustered on chromosome 16. (PubMed id 6089206)1, 3 Karin M....Shows T.B. (1984)
  6. Epigenetic alteration of the metallothionein 1E gene in human endometrial carcinomas. (PubMed id 19420986)1, 9 Tse K.Y....Ngan H.Y. (2009)
  7. Overlapping gene expression profiles of cell migration and tumor invasion in human bladder cancer identify metallothionein 1E and nicotinamide N-methyltransferase as novel regulators of cell migration. (PubMed id 18724390)1, 9 Wu Y....Theodorescu D. (2008)
  8. Metallothionein isoform gene expression in zinc-treated human peripheral blood lymphocytes. (PubMed id 10774930)1, 9 Vandeghinste N....De Ley M. (2000)
  9. Isoform-specific expression of metallothionein mRNA in the developing and adult human kidney. (PubMed id 8619255)1, 9 Mididoddi S....Sens D.A. (1996)
  10. Metallothionein 1 isoform gene expression induced by cadmium in human peripheral blood lymphocytes. (PubMed id 16827180)1, 9 Chang X.L....Zhou Y.F. (2006)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section
 ANDOR
Aliases
Disorders
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section
Entrez Gene: 4493 HGNC: 7397 AceView: MT2_ Ensembl:ENSG00000169715 euGenes: HUgn4493
ECgene: MT1E Kegg: 4493 H-InvDB: MT1E

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
NameDescription
PharmGKB entry for MT1E Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for MT1E gene:
Search GeneIP for patents involving MT1E

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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