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MT1E Gene

protein-coding   GIFtS: 50
GCID: GC16P056659

Metallothionein 1E


(Previous symbol: MT1)
  See MT1E-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Metallothionein 1E1 2     Metallothionein 1E (Functional)2
MT11 2     Metallothionein D2
MT-1E2 3     metallothionein-1E2
MT-IE2 3     metallothionein-IE2
MTD2     Metallothionein-IE3

External Ids:    HGNC: 73971   Entrez Gene: 44932   Ensembl: ENSG000001697157   OMIM: 1563515   UniProtKB: P047323   

Export aliases for MT1E gene to outside databases

Previous GC identifers: GC16U990040 GC16M056702 GC16P056387 GC16P056429 GC16P056435 GC16P055216


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for MT1E Gene:
MT1E (metallothionein 1E) is a protein-coding gene. Diseases associated with MT1E include type 2 diabetes mellitus. GO annotations related to this gene include cadmium ion binding and copper ion binding. An important paralog of this gene is MT1G.

UniProtKB/Swiss-Prot: MT1E_HUMAN, P04732
Function: Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins
are transcriptionally regulated by both heavy metals and glucocorticoids

Gene Wiki entry for MT1E Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Regulatory transcription factor binding sites in the MT1E gene promoter:
         GR   TBP   Sp1   TFIID   GR-beta   GR-alpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMT1E promoter sequence
   Search Chromatin IP Primers for MT1E

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MT1E


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16q13   Ensembl cytogenetic band:  16q12.2   HGNC cytogenetic band: 16q13

MT1E Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MT1E gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16P056659:  view genomic region     (about GC identifiers)

Start:
56,659,387 bp from pter      End:
56,661,024 bp from pter
Size:
1,638 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: MT1E_HUMAN, P04732 (See protein sequence)
Recommended Name: Metallothionein-1E  
Size: 61 amino acids; 6014 Da
Subunit: Monomer
Secondary accessions: A2RRF7 Q86YX4 Q8TD51
Alternative splicing: 2 isoforms:  P04732-1   P04732-2   

Explore the universe of human proteins at neXtProt for MT1E: NX_P04732

Explore proteomics data for MT1E at MOPED


See MT1E Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_783316.2  
ENSEMBL proteins: 
 ENSP00000307706   ENSP00000457516   ENSP00000328137  

MT1E Human Recombinant Protein Products:

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Novus Biologicals MT1E Lysate
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Cloud-Clone Corp. Proteins for MT1E

 
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antibodies-online proteins for MT1E (5 products) 

 
Search antibodies-online for peptides for MT1E

MT1E Antibody Products:

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antibodies-online antibodies for MT1E (6 products) 

MT1E Assay Products:

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antibodies-online kits for MT1E (10 products) 


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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HGNC Gene Families:
MT: Metallothioneins

5 InterPro protein domains:
 IPR000006 Metalthion_vert
 IPR018064 Metalthion_vert_metal_BS
 IPR003019 Metalthion_sfam_euk
 IPR023587 Metalthion_dom_vert
 IPR017854 Metalthion_dom

Graphical View of Domain Structure for InterPro Entry P04732

ProtoNet protein and cluster: P04732

1 Blocks protein domain: IPB002400 Growth factor cystine knot superfamily signature

UniProtKB/Swiss-Prot: MT1E_HUMAN, P04732
Domain: Class I metallothioneins contain 2 metal-binding domains: four divalent ions are chelated within cluster A
of the alpha domain and are coordinated via cysteinyl thiolate bridges to 11 cysteine ligands. Cluster B, the
corresponding region within the beta domain, can ligate three divalent ions to 9 cysteines
Similarity: Belongs to the metallothionein superfamily. Type 1 family


Find genes that share domains with MT1E           About GenesLikeMe


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

     UniProtKB/Swiss-Prot Summary: MT1E_HUMAN, P04732
Function: Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins
are transcriptionally regulated by both heavy metals and glucocorticoids

     Genatlas biochemistry entry for MT1E:
metallothionein 1E cluster

     Gene Ontology (GO): 4 molecular function terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005507copper ion binding ----
GO:0008270zinc ion binding ISS--
GO:0046870cadmium ion binding ----
GO:0046872metal ion binding ----
     
Find genes that share ontologies with MT1E           About GenesLikeMe


Animal Models:
   genOway: Develop your customized and physiologically relevant rodent model for MT1E

miRNA
Products:
    
miRTarBase miRNAs that target MT1E:
hsa-mir-503-5p (MIRT041134)

Block miRNA regulation of human, mouse, rat MT1E using miScript Target Protectors
Search for qRT-PCR Assays for microRNAs that regulate MT1E
Browse SwitchGear 3'UTR luciferase reporter plasmids
Inhib. RNA
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Predesigned siRNA for gene silencing in human, mouse, rat MT1E

Gene Editing
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GenScript: all cDNA clones in your preferred vector: MT1E (NM_175617)
Browse Sino Biological Human cDNA Clones
DNA2.0 Custom Codon Optimized Gene Synthesis Service for MT1E
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MT1E

Cell Line
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Browse ESI BIO Cell Lines and PureStem Progenitors for MT1E 
In Situ Assay
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MT1E


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
nucleus5
extracellular3
cytosol1

Gene Ontology (GO): 3 cellular component terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005634nucleus IDA8619255
GO:0005737cytoplasm IDA8619255
GO:0048471perinuclear region of cytoplasm ISS--

Find genes that share ontologies with MT1E           About GenesLikeMe


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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SuperPaths for MT1E About    
See pathways by source

SuperPathContained pathways About
1Mineral absorption
Mineral absorption


Find genes that share SuperPaths with MT1E           About GenesLikeMe

Pathways by source                                                                                                                                                                 See SuperPaths
Show all pathways



1 Kegg Pathway  (Kegg details for MT1E):
    Mineral absorption

    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for MT1E
Interactions:

    GeneGlobe Interaction Network for MT1E

STRING Interaction Network Preview (showing 5 interactants - click image to see 9)

Selected Interacting proteins for MT1E (ENSP000003077064) via UniProtKB, MINT, STRING, and/or I2D (see all 9)
InteractantInteraction Details
GeneCardExternal ID(s)
ENSG00000204490ENSP000003652904STRING: ENSP00000365290
ENSG00000206439ENSP000003729884STRING: ENSP00000372988
ENSG00000223952ENSP000003894904STRING: ENSP00000389490
ENSG00000228321ENSP000003928584STRING: ENSP00000392858
ENSG00000228849ENSP000004106684STRING: ENSP00000410668
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Gene Ontology (GO): 3 biological process terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0045926negative regulation of growth ISS--
GO:0071276cellular response to cadmium ion IEP16827180
GO:0071294cellular response to zinc ion IEP11168427

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for MT1E

1 HMDB Compound for MT1E    About this table
CompoundSynonyms CAS #PubMed Ids
CadmiumCd (see all 6)7440-43-9--

5 Novoseek inferred chemical compound relationships for MT1E gene    About this table
Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
cadmium 64.6 3 18755257 (1), 8171441 (1), 15952643 (1)
glyceraldehyde 3-phosphate 43 2 9831543 (1), 9422519 (1)
zinc 38.7 23 19083439 (3), 17468938 (1), 10774930 (1)
estrogen 29.1 18 9422519 (6), 10940647 (3), 19420986 (2), 14578200 (1) (see all 5)
copper 16.9 2 9831543 (1), 10940647 (1)



Find genes that share compounds with MT1E           About GenesLikeMe



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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REFSEQ mRNAs for MT1E gene: 
NM_175617.3  

3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000306061(uc002ejl.3) ENST00000568293 ENST00000330439(uc002ejm.3)

miRNA
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Search for qRT-PCR Assays for microRNAs that regulate MT1E
Browse SwitchGear 3'UTR luciferase reporter plasmids
Inhib. RNA
Products:
     
OriGene RNAi products in human, mouse, rat for MT1E
Predesigned siRNA for gene silencing in human, mouse, rat MT1E
Clone
Products:
     
OriGene clones in human, mouse for MT1E (see all 5)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: MT1E (NM_175617)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for MT1E
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MT1E
Primer
Products:
    
Browse OriGene qPCR
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat MT1E
  QuantiTect SYBR Green Assays in human, mouse, rat MT1E
  QuantiFast Probe-based Assays in human, mouse, rat MT1E

Selected AceView cDNA sequences (see all 231):

AI459690 BQ181442 BM817906 BM887687 BX102639 F28873 BM818033 BM766726 
BX281399 BX356856 BQ772005 AJ573772 BU179329 AU107621 AI581831 F28036 
CR621046 BE906482 BQ050782 BQ225213 BM547245 AI952622 D28442 F28406 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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MT1E expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: --
MT1E Expression
About this image

MT1E Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

MT1E Protein Expression
    Custom PCR Arrays for MT1E
Primer
Products:
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QuantiFast Probe-based Assays in human, mouse, rat MT1E
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MT1E

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of human and chimp.

Orthologs for MT1E gene from 1 species (see representative species )    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
chimpanzee
(Pan troglodytes)
Mammalia MT1E6
Pan troglodytes metallothionein 1E (MT1E), mRNA.
93(a)
1 ↔ 1
16(55711209-55712520)


ENSEMBL Gene Tree for MT1E (if available)
TreeFam Gene Tree for MT1E (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Paralogs for MT1E gene
MT1G2  MT1F2  MT1X2  MT1B2  MT2A2  MT1HL12  MT1M2  MT1H2  
MT1A2  
14 SIMAP similar genes for MT1E using alignment to 2 protein entries:     MT1E_HUMAN (see all proteins):
MT1H    MT1J    MTE    MT1X    MT1G    MT1F
MT1M    MT1A    MT1L    MT4    MT3    MT1B
MT1HL1    MT2A

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2 Pseudogenes.org Pseudogenes for MT1E
PGOHUM00000249143 PGOHUM00000259531


(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for MT1E (see all 151)    About this table                                 

Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 16 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs1912893721,2
--56657613(+) ATTAGC/TTATTG 1 -- us2k10--------
rs1449095311,2
C--56657619(+) ATTGC-/TTTTTT 1 -- us2k10--------
rs80618191,2
C,F--56657627(+) tttttA/Taaaaa 1 -- us2k1 tfbs33Minor allele frequency- T:0.33NA 6
rs1121675131,2
F--56657733(+) CACATG/AAACAT 1 -- us2k11Minor allele frequency- A:0.50CSA 2
rs1386893351,2
--56657748(+) CATGTA/GGTCCA 1 -- us2k10--------
rs1117207821,2
F--56657761(+) GAGAGC/TCATTC 1 -- us2k11Minor allele frequency- T:0.50CSA 2
rs1878348551,2
--56657793(+) TCAACA/CCAGGG 1 -- us2k10--------
rs1474192701,2
C--56657810(+) AGCTAC/TGAGCA 1 -- us2k10--------
rs1144101151,2
F--56657934(+) GAAAAG/CCAAAC 1 -- us2k11Minor allele frequency- C:0.02WA 118
rs1921856711,2
C--56657966(+) AAAATC/TGGTCC 1 -- us2k10--------

HapMap Linkage Disequilibrium report for MT1E (56659387 - 56661024 bp)

Structural Variations
     Database of Genomic Variants (DGV) 1 variation for MT1E:    About this table    
Variant IDTypeSubtypePubMed ID
nsv906720CNV Loss21882294

Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing MT1E
DNA2.0 Custom Variant and Variant Library Synthesis for MT1E

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 156351    OMIM disorders: --

1 disease for MT1E:    
About MalaCards
type 2 diabetes mellitus


Find genes that share disorders with MT1E           About GenesLikeMe

5 Novoseek inferred disease relationships for MT1E gene    About this table

Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
breast cancer 33.8 15 10940647 (3), 10917545 (3), 11291768 (2), 9422519 (2) (see all 7)
bladder cancer 29.5 3 11270423 (2), 18724390 (1)
prostate cancer 24.4 1 10754528 (1)
tumors 17.8 5 18724390 (2), 15188022 (1), 18755257 (1)
cancer 0 5 19420986 (2), 18724390 (2)

Genetic Association Database (GAD): MT1E
Human Genome Epidemiology (HuGE) Navigator: MT1E (1 document)

Export disorders for MT1E gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for MT1E gene, integrated from 10 sources (see all 62):
(articles sorted by number of sources associating them with MT1E)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Structure and expression of two human metallothionein-I isoform genes and a related pseudogene. (PubMed id 2581970)1, 2, 3 Schmidt C.J.... Hamer D.H. (J. Biol. Chem. 1985)
  2. Induction by zinc of specific metallothionein isoforms in human monocytes. (PubMed id 8119276)1, 2, 9 Pauwels M.... Ley M. (Eur. J. Biochem. 1994)
  3. Polymorphisms in metallothionein-1 and -2 genes associated with the risk of type 2 diabetes mellitus and its complications. (PubMed id 18349110)1, 4 Yang L....Liu Y. (Am. J. Physiol. Endocrinol. Metab. 2008)
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
  5. Human metallothionein genes are clustered on chromosome 16. (PubMed id 6089206)1, 3 Karin M....Shows T.B. (Proc. Natl. Acad. Sci. U.S.A. 1984)
  6. Epigenetic alteration of the metallothionein 1E gene in human endometrial carcinomas. (PubMed id 19420986)1, 9 Tse K.Y....Ngan H.Y. (Tumour Biol. 2009)
  7. Overlapping gene expression profiles of cell migration and tumor invasion in human bladder cancer identify metallothionein 1E and nicotinamide N-methyltransferase as novel regulators of cell migration. (PubMed id 18724390)1, 9 Wu Y....Theodorescu D. (Oncogene 2008)
  8. Metallothionein isoform gene expression in zinc-treated human peripheral blood lymphocytes. (PubMed id 10774930)1, 9 Vandeghinste N....De Ley M. (Cell. Mol. Biol. (Noisy-le-grand) 2000)
  9. Isoform-specific expression of metallothionein mRNA in the developing and adult human kidney. (PubMed id 8619255)1, 9 Mididoddi S....Sens D.A. (Toxicol. Lett. 1996)
  10. Metallothionein 1 isoform gene expression induced by cadmium in human peripheral blood lymphocytes. (PubMed id 16827180)1, 9 Chang X.L....Zhou Y.F. (Biomed. Environ. Sci. 2006)

(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
Aliases
Disorders
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 4493 HGNC: 7397 AceView: MT2_ Ensembl:ENSG00000169715 euGenes: HUgn4493
ECgene: MT1E Kegg: 4493 H-InvDB: MT1E

(According to HUGE)
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  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for MT1E Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for MT1E gene:
Search GeneIP for patents involving MT1E

GeneCards and IP:
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(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from genOway)
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 Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
 Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for MT1E  
 Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for MT1E  
 OriGene MassSpec for MT1E   OriGene clones in human, mouse for MT1E  
 Browse OriGene qSTAR qPCR primer pairs   OriGene Purified Protein for MT1E  
 Browse OriGene ORF clones   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
 OriGene Custom Antibody Services for MT1E   OriGene Custom Protein Services for MT1E  

 
 
 Block miRNA regulation of human, mouse, rat MT1E using miScript Target Protectors SeqTarget long-range PCR primers for resequencing MT1E
 DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MT1E Predesigned siRNA for gene silencing in human, mouse, rat MT1E
 QuantiFast Probe-based Assays in human, mouse, rat MT1E QuantiTect SYBR Green Assays in human, mouse, rat MT1E
 Custom PCR Arrays for MT1E Search Chromatin IP Primers for MT1E
 Pre-validated RT2 qPCR Primer Assay in human, mouse, rat MT1E  GeneGlobe Interaction Network for MT1E
 Regulatory tfbs in MT1E promoter
 GenScript Custom Purified and Recombinant Proteins Services for MT1E GenScript cDNA clones with any tag delivered in your preferred vector for MT1E
 GenScript Custom Assay Services for MT1E GenScript Custom overexpressing Cell Line Services for MT1E
 CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
 Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
 Plasmid Preparation Custom Peptide Services
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 Search Tocris compounds for MT1E
 Browse Sino Biological Proteins
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 Protein Production Services
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 Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

 Novus Tissue Slides
 MT1E antibodies
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 MT1E lysates
 Search for Antibodies for MT1E at Abcam
 See all of Abcam's Antibodies, Kits and Proteins for MT1E
 Custom Antibody / Protein Production Service
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 Browse ProSpec Recombinant Proteins
 Proteins for MT1E
 Antibodies for MT1E
 ELISAs for MT1E
 CLIAs for MT1E



 Browse ESI BIO Cell Lines and PureStem Progenitors for MT1E
 Gene Synthesis
 Protein Engineering
 Variant Library Synthesis
 Codon Optimization
 Protein Production and Purification
 Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MT1E
 Browse SwitchGear 3'UTR luciferase reporter plasmids for MT1E
 SwitchGear Promoter luciferase reporter plasmids for MT1E
 Search ThermoFisher Antibodies for MT1E
 Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MT1E
 Browse compounds at ApexBio
 Search Addgene for plasmids for MT1E
  Search eBioscience for proteins for MT1E
  Search eBioscience for elisas for MT1E
  eBioscience FlowRNA Probe Sets
 genOway: Develop your customized and physiologically relevant rodent model for MT1E
 antibodies-online antibodies for MT1E (6 products)
 antibodies-online kits for MT1E (10 products)
  Search antibodies-online for peptides for MT1E
 antibodies-online proteins for MT1E (5 products)
       
GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014 , 7 Oct 2014

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