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Aliases for MT1DP Gene

Aliases for MT1DP Gene

  • Metallothionein 1D, Pseudogene (Functional) 2 3
  • MTM 3 4
  • Metallothionein 1D (Pseudogene) 3
  • Metallothionein 1D, Pseudogene 2
  • Metallothionein 1A Pseudogene 3
  • Metallothionein M 3

External Ids for MT1DP Gene

Previous GeneCards Identifiers for MT1DP Gene

  • GC16U990039
  • GC16P055236
  • GC16P056677
  • GC16P042547

Summaries for MT1DP Gene

GeneCards Summary for MT1DP Gene

MT1DP (Metallothionein 1D, Pseudogene (Functional)) is a Pseudogene.

UniProtKB/Swiss-Prot for MT1DP Gene

  • Metallothioneins have a high content of cysteine residues that bind various heavy metals.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MT1DP Gene

Genomics for MT1DP Gene

Regulatory Elements for MT1DP Gene

Transcription factor binding sites by QIAGEN in the MT1DP gene promoter:

Genomic Location for MT1DP Gene

Start:
56,643,687 bp from pter
End:
56,644,941 bp from pter
Size:
1,255 bases
Orientation:
Plus strand

Genomic View for MT1DP Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MT1DP Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MT1DP Gene

Proteins for MT1DP Gene

  • Protein details for MT1DP Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A1L3X4-MT1DP_HUMAN
    Recommended name:
    Putative metallothionein MT1DP
    Protein Accession:
    A1L3X4
    Secondary Accessions:
    • Q86YX1

    Protein attributes for MT1DP Gene

    Size:
    49 amino acids
    Molecular mass:
    4983 Da
    Quaternary structure:
    No Data Available

neXtProt entry for MT1DP Gene

Proteomics data for MT1DP Gene at MOPED

Post-translational modifications for MT1DP Gene

No Post-translational modifications

No data available for DME Specific Peptides for MT1DP Gene

Domains for MT1DP Gene

Gene Families for MT1DP Gene

HGNC:
  • MT :Metallothioneins

Protein Domains for MT1DP Gene

Suggested Antigen Peptide Sequences for MT1DP Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

A1L3X4

UniProtKB/Swiss-Prot:

MT1DP_HUMAN :
  • A1L3X4
Family:
  • Belongs to the metallothionein superfamily. Type 1 family.
genes like me logo Genes that share domains with MT1DP: view

Function for MT1DP Gene

Molecular function for MT1DP Gene

GENATLAS Biochemistry: metallothionein 1DP cluster
UniProtKB/Swiss-Prot Function: Metallothioneins have a high content of cysteine residues that bind various heavy metals.

Gene Ontology (GO) - Molecular Function for MT1DP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with MT1DP: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MT1DP Gene

Localization for MT1DP Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for MT1DP Gene COMPARTMENTS Subcellular localization image for MT1DP gene
Compartment Confidence
extracellular 3
cytosol 1
nucleus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for MT1DP Gene

Pathways for MT1DP Gene

SuperPathways for MT1DP Gene

No Data Available

Interacting Proteins for MT1DP Gene

Gene Ontology (GO) - Biological Process for MT1DP Gene

None

No data available for Pathways by source for MT1DP Gene

Transcripts for MT1DP Gene

mRNA/cDNA for MT1DP Gene

(5) Additional mRNA sequences :
(1) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for MT1DP Gene

Metallothionein 1D, pseudogene:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for MT1DP

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MT1DP Gene

No ASD Table

Relevant External Links for MT1DP Gene

GeneLoc Exon Structure for
MT1DP
ECgene alternative splicing isoforms for
MT1DP

Expression for MT1DP Gene

mRNA expression in normal human tissues for MT1DP Gene

mRNA differential expression in normal tissues according to GTEx for MT1DP Gene

This gene is overexpressed in Liver (38.1).

SOURCE GeneReport for Unigene cluster for MT1DP Gene Hs.679600

genes like me logo Genes that share expressions with MT1DP: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein expression and mRNA Expression by UniProt/SwissProt for MT1DP Gene

Orthologs for MT1DP Gene

Evolution for MT1DP Gene

ENSEMBL:
Gene Tree for MT1DP (if available)
TreeFam:
Gene Tree for MT1DP (if available)

No data available for Orthologs for MT1DP Gene

Paralogs for MT1DP Gene

Selected SIMAP similar genes for MT1DP Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with MT1DP: view

No data available for Paralogs for MT1DP Gene

Variants for MT1DP Gene

Sequence variations from dbSNP and Humsavar for MT1DP Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type MAF
rs1599823 -- 56,641,905(-) GTCAA(A/G)GAGTT upstream-variant-2KB
rs1610212 -- 56,643,283(-) CTTCG(C/G)CTCTG upstream-variant-2KB
rs1610213 -- 56,642,169(-) tgttc(A/G)aggta upstream-variant-2KB
rs1610214 -- 56,641,976(-) AAGGG(A/T)TGTAT upstream-variant-2KB
rs4783948 -- 56,642,419(+) ccaat(C/T)agaag upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MT1DP Gene

Variant ID Type Subtype PubMed ID
nsv906720 CNV Loss 21882294

Relevant External Links for MT1DP Gene

HapMap Linkage Disequilibrium report
MT1DP

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MT1DP Gene

Disorders for MT1DP Gene

No disorders were found for MT1DP Gene.

No data available for UniProtKB/Swiss-Prot for MT1DP Gene

Publications for MT1DP Gene

  1. Human metallothionein genes are clustered on chromosome 16. (PMID: 6089206) Karin M. … Shows T.B. (Proc. Natl. Acad. Sci. U.S.A. 1984) 2 3
  2. Structural and functional analysis of the human metallothionein-IA gene: differential induction by metal ions and glucocorticoids. (PMID: 6327055) Richards R.I. … Karin M. (Cell 1984) 2 3
  3. Structure and tissue-specific expression of the human metallothionein IB gene. (PMID: 3785191) Heguy A. … Karin M. (Mol. Cell. Biol. 1986) 2 3
  4. Tumor suppressor long non-coding RNA, MT1DP is negatively regulated by YAP and Runx2 to inhibit FoxA1 in liver cancer cells. (PMID: 25261601) Yu W. … Wang J. (Cell. Signal. 2014) 2 3
  5. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3

Products for MT1DP Gene

Sources for MT1DP Gene

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