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Aliases for MT1DP Gene

Aliases for MT1DP Gene

  • Metallothionein 1D, Pseudogene 2 3 5
  • Metallothionein 1D, Pseudogene (Functional) 2 3
  • MTM 3 4
  • Metallothionein 1A Pseudogene 3
  • Metallothionein M 3

External Ids for MT1DP Gene

Previous GeneCards Identifiers for MT1DP Gene

  • GC16U990039
  • GC16P055236
  • GC16P056677
  • GC16P042547

Summaries for MT1DP Gene

GeneCards Summary for MT1DP Gene

MT1DP (Metallothionein 1D, Pseudogene) is a Pseudogene.

UniProtKB/Swiss-Prot for MT1DP Gene

  • Metallothioneins have a high content of cysteine residues that bind various heavy metals.

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MT1DP Gene

Genomics for MT1DP Gene

Regulatory Elements for MT1DP Gene

Enhancers for MT1DP Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH16G056576 1 ENCODE 11.4 -66.5 -66488 0.9 PKNOX1 ARID4B ZNF48 YY1 ZNF207 ZNF143 ZNF263 REST MIER2 TBX21 MT1DP MT1CP MT1X MT1F MT1B MT4 GC16P056575 MT3
GH16G056616 0.9 ENCODE dbSUPER 11.4 -25.9 -25857 1.9 RNF2 SUZ12 TAF1 CBX2 MAX RBBP5 RAD21 YY1 HDAC2 POLR2A MT1A MT1F MT1G MT1H MT1CP MT1DP MT1B MT3 MT1E MT1X
GH16G056642 0.8 ENCODE 8.8 -0.2 -178 1.3 ATF1 RAD21 YY1 EGR1 SMARCC1 SP5 ZBTB2 GATAD2B MIER2 REST MT1A MT1DP MT1E
GH16G056621 0.5 dbSUPER 11.4 -22.2 -22234 0.6 TAL1 HNF4A PRDM1 SP7 RXRB MT1F MT1G MT1H MT1DP MT1CP MT1B MT3 MT1X NUP93 MIR138-2
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MT1DP on UCSC Golden Path with GeneCards custom track

Promoters for MT1DP Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000086303 -187 201 CTCF ATF1 SUZ12 MAX RAD21 YY1 EGR1 POLR2A SMC3 EZH2

Transcription factor binding sites by QIAGEN in the MT1DP gene promoter:

Genomic Location for MT1DP Gene

56,643,687 bp from pter
56,644,941 bp from pter
1,255 bases
Plus strand

Genomic View for MT1DP Gene

Genes around MT1DP on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MT1DP Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MT1DP Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MT1DP Gene

Proteins for MT1DP Gene

  • Protein details for MT1DP Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Putative metallothionein MT1DP
    Protein Accession:
    Secondary Accessions:
    • Q86YX1

    Protein attributes for MT1DP Gene

    49 amino acids
    Molecular mass:
    4983 Da
    Quaternary structure:
    No Data Available

neXtProt entry for MT1DP Gene

Post-translational modifications for MT1DP Gene

No Post-translational modifications

No data available for DME Specific Peptides for MT1DP Gene

Domains & Families for MT1DP Gene

Protein Domains for MT1DP Gene

Suggested Antigen Peptide Sequences for MT1DP Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the metallothionein superfamily. Type 1 family.
  • Belongs to the metallothionein superfamily. Type 1 family.
genes like me logo Genes that share domains with MT1DP: view

Function for MT1DP Gene

Molecular function for MT1DP Gene

GENATLAS Biochemistry:
metallothionein 1DP cluster
UniProtKB/Swiss-Prot Function:
Metallothioneins have a high content of cysteine residues that bind various heavy metals.

Gene Ontology (GO) - Molecular Function for MT1DP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with MT1DP: view

Phenotypes for MT1DP Gene

GenomeRNAi human phenotypes for MT1DP:
genes like me logo Genes that share phenotypes with MT1DP: view

Animal Model Products

Inhibitory RNA Products

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MT1DP Gene

Localization for MT1DP Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MT1DP Gene

Pathways & Interactions for MT1DP Gene

SuperPathways for MT1DP Gene

No Data Available

Interacting Proteins for MT1DP Gene

Gene Ontology (GO) - Biological Process for MT1DP Gene


No data available for Pathways by source and SIGNOR curated interactions for MT1DP Gene

Drugs & Compounds for MT1DP Gene

No Compound Related Data Available

Transcripts for MT1DP Gene

mRNA/cDNA for MT1DP Gene

(1) REFSEQ mRNAs :
(5) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for MT1DP Gene

Metallothionein 1D, pseudogene:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MT1DP Gene

No ASD Table

Relevant External Links for MT1DP Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MT1DP Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MT1DP Gene

mRNA differential expression in normal tissues according to GTEx for MT1DP Gene

This gene is overexpressed in Liver (x38.1).

NURSA nuclear receptor signaling pathways regulating expression of MT1DP Gene:


SOURCE GeneReport for Unigene cluster for MT1DP Gene:

genes like me logo Genes that share expression patterns with MT1DP: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MT1DP Gene

Orthologs for MT1DP Gene

Evolution for MT1DP Gene

Gene Tree for MT1DP (if available)
Gene Tree for MT1DP (if available)

No data available for Orthologs for MT1DP Gene

Paralogs for MT1DP Gene

(2) SIMAP similar genes for MT1DP Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with MT1DP: view

No data available for Paralogs for MT1DP Gene

Variants for MT1DP Gene

Sequence variations from dbSNP and Humsavar for MT1DP Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
rs1001609629 -- 56,644,965(+) TGAGG(A/G)GGTGT downstream-variant-500B
rs1002418535 -- 56,645,222(+) AGATG(C/T)GAAGA downstream-variant-500B
rs1004438667 -- 56,643,524(+) CGGCC(C/T)GCCTG upstream-variant-2KB
rs1006110109 -- 56,644,747(+) AAATG(A/T)GCCCA nc-transcript-variant
rs1006550860 -- 56,641,809(+) GGATT(C/G)CTGCC upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MT1DP Gene

Variant ID Type Subtype PubMed ID
dgv2988n100 CNV gain 25217958
dgv2989n100 CNV gain 25217958
dgv524e214 CNV gain 21293372
nsv1058153 CNV gain 25217958
nsv474249 CNV novel sequence insertion 20440878

Relevant External Links for MT1DP Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MT1DP Gene

Disorders for MT1DP Gene

Relevant External Links for MT1DP

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MT1DP Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MT1DP Gene

Publications for MT1DP Gene

  1. Tumor suppressor long non-coding RNA, MT1DP is negatively regulated by YAP and Runx2 to inhibit FoxA1 in liver cancer cells. (PMID: 25261601) Yu W. … Wang J. (Cell. Signal. 2014) 2 3 64
  2. Structure and tissue-specific expression of the human metallothionein IB gene. (PMID: 3785191) Heguy A. … Karin M. (Mol. Cell. Biol. 1986) 2 3 64
  3. Human metallothionein genes are clustered on chromosome 16. (PMID: 6089206) Karin M. … Shows T.B. (Proc. Natl. Acad. Sci. U.S.A. 1984) 2 3 64
  4. Structural and functional analysis of the human metallothionein-IA gene: differential induction by metal ions and glucocorticoids. (PMID: 6327055) Richards R.I. … Karin M. (Cell 1984) 2 3 64
  5. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3 64

Products for MT1DP Gene

Sources for MT1DP Gene

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