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Aliases for MT1DP Gene

Aliases for MT1DP Gene

  • Metallothionein 1D, Pseudogene 2 3 5
  • MTM 3 4
  • Metallothionein 1D, Pseudogene (Functional) 3
  • Metallothionein 1A Pseudogene 3
  • Metallothionein M 3

External Ids for MT1DP Gene

Previous GeneCards Identifiers for MT1DP Gene

  • GC16U990039
  • GC16P055236
  • GC16P056677
  • GC16P042547

Summaries for MT1DP Gene

GeneCards Summary for MT1DP Gene

MT1DP (Metallothionein 1D, Pseudogene) is a Pseudogene.

UniProtKB/Swiss-Prot for MT1DP Gene

  • Metallothioneins have a high content of cysteine residues that bind various heavy metals.

Additional gene information for MT1DP Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MT1DP Gene

Genomics for MT1DP Gene

GeneHancer (GH) Regulatory Elements for MT1DP Gene

Promoters and enhancers for MT1DP Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH16I056642 Promoter/Enhancer 1.3 Ensembl ENCODE 558.9 -0.2 -177 1.3 CTCF USF1 ATF1 TAF1 MAX RAD21 ZNF7 YY1 CTBP1 POLR2A MT1DP MT1A MT1E
GH16I056604 Promoter/Enhancer 2.8 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 11.5 -33.5 -33531 10.8 HDGF PKNOX1 FOXA2 SMAD1 MLX ZFP64 ARID4B SIN3A FEZF1 DMAP1 MT2A ENSG00000260823 GC16P056608 GC16P056609 RSPRY1 POLR2C BBS2 MT1A MT1F MT1G
GH16I056616 Promoter/Enhancer 1.3 Ensembl ENCODE dbSUPER 11.4 -25.9 -25856 1.9 RXRA TAF1 SUZ12 MAX REST RAD21 YY1 SP1 POLR2A CTBP2 MT1L MT1A MT1F MT1G MT1H MT1CP MT1DP MT1B MT3 MT1E
GH16I056576 Enhancer 0.8 ENCODE 11.4 -66.5 -66487 0.9 ELF3 RB1 ARID4B SIN3A RAD21 RFX5 ZNF207 ZNF143 RCOR1 RUNX3 MT1DP MT1CP MT1X MT1F MT1B MT4 GC16P056575 MT3
GH16I056621 Enhancer 0.5 dbSUPER 11.4 -22.2 -22234 0.6 SKI RXRA CBFA2T3 HNF4A PRDM1 SP7 RXRB MT1F MT1G MT1H MT1DP MT1CP MT1B MT3 MT1X NUP93 MIR138-2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MT1DP on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the MT1DP gene promoter:

Genomic Locations for MT1DP Gene

Genomic Locations for MT1DP Gene
chr16:56,643,687-56,644,941
(GRCh38/hg38)
Size:
1,255 bases
Orientation:
Plus strand
chr16:56,677,599-56,678,853
(GRCh37/hg19)

Genomic View for MT1DP Gene

Genes around MT1DP on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MT1DP Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MT1DP Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MT1DP Gene

Proteins for MT1DP Gene

  • Protein details for MT1DP Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A1L3X4-MT1DP_HUMAN
    Recommended name:
    Putative metallothionein MT1DP
    Protein Accession:
    A1L3X4
    Secondary Accessions:
    • Q86YX1

    Protein attributes for MT1DP Gene

    Size:
    49 amino acids
    Molecular mass:
    4983 Da
    Quaternary structure:
    No Data Available

neXtProt entry for MT1DP Gene

Post-translational modifications for MT1DP Gene

No Post-translational modifications

No data available for DME Specific Peptides for MT1DP Gene

Domains & Families for MT1DP Gene

Protein Domains for MT1DP Gene

Suggested Antigen Peptide Sequences for MT1DP Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

A1L3X4

UniProtKB/Swiss-Prot:

MT1DP_HUMAN :
  • Belongs to the metallothionein superfamily. Type 1 family.
Family:
  • Belongs to the metallothionein superfamily. Type 1 family.
genes like me logo Genes that share domains with MT1DP: view

Function for MT1DP Gene

Molecular function for MT1DP Gene

GENATLAS Biochemistry:
metallothionein 1DP cluster
UniProtKB/Swiss-Prot Function:
Metallothioneins have a high content of cysteine residues that bind various heavy metals.

Gene Ontology (GO) - Molecular Function for MT1DP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with MT1DP: view

Phenotypes for MT1DP Gene

GenomeRNAi human phenotypes for MT1DP:
genes like me logo Genes that share phenotypes with MT1DP: view

Animal Model Products

Inhibitory RNA Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MT1DP Gene

Localization for MT1DP Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MT1DP Gene

Pathways & Interactions for MT1DP Gene

SuperPathways for MT1DP Gene

No Data Available

Interacting Proteins for MT1DP Gene

Gene Ontology (GO) - Biological Process for MT1DP Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MT1DP Gene

Drugs & Compounds for MT1DP Gene

(1) Drugs for MT1DP Gene - From: DrugBank

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Copper Approved, Investigational Pharma Carrier, binder 202
genes like me logo Genes that share compounds with MT1DP: view

Transcripts for MT1DP Gene

mRNA/cDNA for MT1DP Gene

(1) REFSEQ mRNAs :
(5) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for MT1DP Gene

Metallothionein 1D, pseudogene:
Representative Sequences:

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for MT1DP Gene

No ASD Table

Relevant External Links for MT1DP Gene

GeneLoc Exon Structure for
MT1DP
ECgene alternative splicing isoforms for
MT1DP

Expression for MT1DP Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MT1DP Gene

mRNA differential expression in normal tissues according to GTEx for MT1DP Gene

This gene is overexpressed in Liver (x38.1).

NURSA nuclear receptor signaling pathways regulating expression of MT1DP Gene:

MT1DP

SOURCE GeneReport for Unigene cluster for MT1DP Gene:

Hs.679600
genes like me logo Genes that share expression patterns with MT1DP: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MT1DP Gene

Orthologs for MT1DP Gene

Evolution for MT1DP Gene

ENSEMBL:
Gene Tree for MT1DP (if available)
TreeFam:
Gene Tree for MT1DP (if available)

No data available for Orthologs for MT1DP Gene

Paralogs for MT1DP Gene

(2) SIMAP similar genes for MT1DP Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with MT1DP: view

No data available for Paralogs for MT1DP Gene

Variants for MT1DP Gene

Sequence variations from dbSNP and Humsavar for MT1DP Gene

SNP ID Clin Chr 16 pos Variation AA Info Type
rs1001609629 -- 56,644,965(+) G/A downstream_transcript_variant
rs1002418535 -- 56,645,222(+) T/C downstream_transcript_variant
rs1004438667 -- 56,643,524(+) C/T upstream_transcript_variant
rs1006110109 -- 56,644,747(+) T/A non_coding_transcript_variant
rs1006550860 -- 56,641,809(+) C/G upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MT1DP Gene

Variant ID Type Subtype PubMed ID
dgv2988n100 CNV gain 25217958
dgv2989n100 CNV gain 25217958
dgv524e214 CNV gain 21293372
nsv1058153 CNV gain 25217958
nsv474249 CNV novel sequence insertion 20440878

Additional Variant Information for MT1DP Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MT1DP

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MT1DP Gene

Disorders for MT1DP Gene

Additional Disease Information for MT1DP

No disorders were found for MT1DP Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MT1DP Gene

Publications for MT1DP Gene

  1. Tumor suppressor long non-coding RNA, MT1DP is negatively regulated by YAP and Runx2 to inhibit FoxA1 in liver cancer cells. (PMID: 25261601) Yu W … Wang J (Cellular signalling 2014) 2 3 58
  2. Structure and tissue-specific expression of the human metallothionein IB gene. (PMID: 3785191) Heguy A … Karin M (Molecular and cellular biology 1986) 2 3 58
  3. Human metallothionein genes are clustered on chromosome 16. (PMID: 6089206) Karin M … Shows TB (Proceedings of the National Academy of Sciences of the United States of America 1984) 2 3 58
  4. Structural and functional analysis of the human metallothionein-IA gene: differential induction by metal ions and glucocorticoids. (PMID: 6327055) Richards RI … Karin M (Cell 1984) 2 3 58
  5. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T … Vidal M (Cell 2014) 3 58

Products for MT1DP Gene

Sources for MT1DP Gene

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