Aliases for MT-TT Gene
Subcategory (RNA class) for MT-TT Gene
non-coding RNA
Quality Score for this RNA gene is
3
Aliases for MT-TT Gene
External Ids for MT-TT Gene
- HGNC: 7499
- Entrez Gene: 4576
- Ensembl: ENSG00000210195
- OMIM: 590090
Previous HGNC Symbols for MT-TT Gene
- MTTT
- LIMM
Previous GeneCards Identifiers for MT-TT Gene
- GC00U921614
Summaries for MT-TT Gene
GeneCards Summary for MT-TT Gene
MT-TT (Mitochondrially Encoded TRNA Threonine) is an RNA Gene, and is affiliated with the non-coding RNA class. Diseases associated with MT-TT include Parkinson Disease, Mitochondrial and Mitochondrial Myopathy, Lethal, Infantile. Among its related pathways are tRNA Aminoacylation.
Additional gene information for MT-TT Gene
- Monarch Initiative
- Search for MT-TT at DataMed
- Search for MT-TT at HumanCyc
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MT-TT Gene
Genomics for MT-TT Gene
Regulatory Element Products
Genomic Locations for MT-TT Gene
Genomic Locations for MT-TT Gene
- chrMT:15,888-15,953
- (GRCh38/hg38)
- Size:
- 66 bases
- Orientation:
- Plus strand
- chrMT:15,888-15,953
- (GRCh37/hg19)
Genomic View for MT-TT Gene
RefSeq DNA sequence for MT-TT Gene
No data available for GeneHancer (GH) Regulatory Elements for MT-TT Gene
Proteins for MT-TT Gene
Post-translational modifications for MT-TT Gene
No Post-translational modifications
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for MT-TT
- Origene Custom Protein Services for MT-TT
- Search GeneTex for Proteins for MT-TT
No data available for DME Specific Peptides for MT-TT Gene
Domains & Families for MT-TT Gene
Gene Families for MT-TT Gene
Graphical View of Domain Structure for InterPro Entry
No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MT-TT Gene
Function for MT-TT Gene
Phenotypes for MT-TT Gene
- GenomeRNAi human phenotypes for MT-TT:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Search ViGene Biosciences for MT-TT
CRISPR Products
- Browse CRISPR knockouts for MT-TT
- Applied Biological Materials CRISPR for MT-TT
-
Vectors and viruses for KO, Activation, Repression, and more
miRNA Products
- Search ViGene Biosciences for MT-TT
Inhibitory RNA Products
- Search ViGene Biosciences for MT-TT
Clone Products
- GenScript: Custom all cDNA clones Services for MT-TT
- Applied Biological Materials Clones for MT-TT
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MT-TT Gene
Localization for MT-TT Gene
| Compartment | Confidence |
|---|---|
| mitochondrion | 2 |
| nucleus | 2 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MT-TT Gene
Pathways & Interactions for MT-TT Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | tRNA Aminoacylation | ||
Pathways by source for MT-TT Gene
1 KEGG pathway for MT-TT Gene
Interacting Proteins for MT-TT Gene
No data available for SIGNOR curated interactions for MT-TT Gene
Transcripts for MT-TT Gene
mRNA/cDNA for MT-TT Gene
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
- Browse CRISPR knockouts for MT-TT
- Applied Biological Materials CRISPR for MT-TT
-
Vectors and viruses for KO, Activation, Repression, and more
miRNA Products
- Search ViGene Biosciences for MT-TT
Inhibitory RNA Products
- Search ViGene Biosciences for MT-TT
Clone Products
- GenScript: Custom all cDNA clones Services for MT-TT
- Applied Biological Materials Clones for MT-TT
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for MT-TT Gene
Phenotype-based relationships between genes and organs from Gene ORGANizer for MT-TT Gene
Germ Layers:
- mesoderm
Systems:
- skeletal muscle
Primer Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Evidence on tissue expression from TISSUES for MT-TT Gene
Orthologs for MT-TT Gene
No data available for Orthologs for MT-TT Gene
Paralogs for MT-TT Gene
No data available for Paralogs for MT-TT Gene
Variants for MT-TT Gene
Additional Variant Information for MT-TT Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MT-TT Gene
Disorders for MT-TT Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| parkinson disease, mitochondrial |
|
|
| mitochondrial myopathy, lethal, infantile |
|
|
| mitochondrial disorders |
|
|
| myasthenic syndrome, congenital, 10 |
|
|
Search MT-TT in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for MT-TT
- Genetic Association Database
- (GAD)
No data available for UniProtKB/Swiss-Prot and Genatlas for MT-TT Gene
Publications for MT-TT Gene
- A mitochondrial DNA variant associated with left ventricular hypertrophy in diabetes. (PMID: 14680844) Momiyama Y … Matsuoka R (Biochemical and biophysical research communications 2003) 3 44 58
- [The mitochondrial tRNA(Thr) A15951G mutation may be associated with Leber's hereditary optic neuropathy in two Chinese families]. (PMID: 21983721) Zhang Y … Guan MX (Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics 2011) 3 58
- Comprehensive analysis of common mitochondrial DNA variants and colorectal cancer risk. (PMID: 19050702) Webb E … Houlston RS (British journal of cancer 2008) 3 58
Products for MT-TT Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for MT-TT
- Origene Custom Protein Services for MT-TT
- Browse OriGene Inhibitory RNA Products For MT-TT
- Browse OriGene qPCR primer pairs and template standards
- Browse CRISPR knockouts for MT-TT
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For MT-TT
- GenScript: Custom all cDNA clones Services for MT-TT
- GenScript Custom Purified and Recombinant Proteins Services for MT-TT
- GenScript Custom Assay Services for MT-TT
- GenScript Custom overexpressing Cell Line Services for MT-TT
- Browse GenScript CRISPR for MT-TT
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for MT-TT
- Browse Sino Biological cDNA Clones
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse Sino Biological ELISA Kits
- Browse Sino Biological ELISA Pair Sets
- Browse Sino Biological CRO Services
- Browse Sino Biological Control Vectors
- Sino Biological Transfection Reagent
- Sino Biological Anti-His Tag Antibody
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Browse Antibodies at Cloud-Clone Corp.
- Browse Proteins at Cloud-Clone Corp.
- Browse Assay Kits at Cloud-Clone Corp.
- Browse Knockouts at Cloud-Clone Corp.
- Browse Knockins at Cloud-Clone Corp.
- Cloud-Clone Corp. disease models service
- Browse cDNA clones at Cloud-Clone Corp.
- Browse primers at Cloud-Clone Corp.
- Cloud-Clone Corp. primary cells service
- Search GeneTex for Antibodies for MT-TT
- Search GeneTex for Proteins for MT-TT
- Search ViGene Biosciences for MT-TT
Sources for MT-TT Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew