Aliases for MT-TT Gene
Subcategory (RNA class) for MT-TT Gene
non-coding RNA
Quality Score for this RNA gene is
3
Aliases for MT-TT Gene
External Ids for MT-TT Gene
- HGNC: 7499
- Entrez Gene: 4576
- Ensembl: ENSG00000210195
- OMIM: 590090
Previous HGNC Symbols for MT-TT Gene
- MTTT
- LIMM
Previous GeneCards Identifiers for MT-TT Gene
- GC00U921614
Summaries for MT-TT Gene
GeneCards Summary for MT-TT Gene
MT-TT (Mitochondrially Encoded TRNA Threonine) is an RNA Gene, and is affiliated with the non-coding RNA class. Diseases associated with MT-TT include Infantile Myopathy And Lactic Acidosis and Mt-Tt Related Parkinson Disease Susceptibility. Among its related pathways are tRNA Aminoacylation.
No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MT-TT Gene
Genomics for MT-TT Gene
Regulatory Element Products
Genomic Location for MT-TT Gene
- Chromosome:
- MT
- Start:
- 15,888 bp from pter
- End:
- 15,953 bp from pter
- Size:
- 66 bases
- Orientation:
- Plus strand
Genomic View for MT-TT Gene
RefSeq DNA sequence for MT-TT Gene
No data available for Regulatory Elements for MT-TT Gene
Proteins for MT-TT Gene
Post-translational modifications for MT-TT Gene
No Post-translational modifications
Antibody Products
- Search GeneTex for Antibodies for MT-TT
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for MT-TT
- Origene Custom Protein Services for MT-TT
- Search GeneTex for Proteins for MT-TT
Assay Products
No data available for DME Specific Peptides for MT-TT Gene
Domains & Families for MT-TT Gene
Gene Families for MT-TT Gene
Graphical View of Domain Structure for InterPro Entry
No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MT-TT Gene
Function for MT-TT Gene
Phenotypes for MT-TT Gene
- GenomeRNAi human phenotypes for MT-TT:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Search ViGene Biosciences for MT-TT
CRISPR Products
- Browse CRISPR knockouts for MT-TT
miRNA Products
- Search ViGene Biosciences for MT-TT
Inhibitory RNA Products
- Search ViGene Biosciences for MT-TT
Cell Line Products
- Search ViGene Biosciences for MT-TT
Flow Cytometry Products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MT-TT Gene
Localization for MT-TT Gene
| Compartment | Confidence |
|---|---|
| chloroplast | 3 |
| mitochondrion | 2 |
| nucleus | 2 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for MT-TT Gene
Pathways & Interactions for MT-TT Gene
More details on SuperPathways for MT-TT| Superpath | Contained pathways | |
|---|---|---|
| 1 | tRNA Aminoacylation |
Pathways by source for MT-TT Gene
1 KEGG pathway for MT-TT Gene
Interacting Proteins for MT-TT Gene
No data available for SIGNOR curated interactions for MT-TT Gene
Transcripts for MT-TT Gene
mRNA/cDNA for MT-TT Gene
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
- Browse CRISPR knockouts for MT-TT
miRNA Products
- Search ViGene Biosciences for MT-TT
Inhibitory RNA Products
- Search ViGene Biosciences for MT-TT
Flow Cytometry Products
Expression for MT-TT Gene
Primer Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MT-TT Gene
Orthologs for MT-TT Gene
Evolution for MT-TT Gene
No data available for Orthologs for MT-TT Gene
Paralogs for MT-TT Gene
No data available for Paralogs for MT-TT Gene
Variants for MT-TT Gene
Relevant External Links for MT-TT Gene
- Human Gene Mutation Database (HGMD)
- MT-TT
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MT-TT Gene
Disorders for MT-TT Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| infantile myopathy and lactic acidosis |
|
|
| mt-tt related parkinson disease susceptibility |
|
|
| parkinson disease susceptibility |
|
|
| lethal infantile mitochondrial myopathy |
|
|
| mitochondrial disorders |
|
|
Search MT-TT in MalaCards
View complete list of genes associated with diseases
Relevant External Links for MT-TT
- Genetic Association Database (GAD)
- MT-TT
No data available for UniProtKB/Swiss-Prot and Genatlas for MT-TT Gene
Publications for MT-TT Gene
- A mitochondrial DNA variant associated with left ventricular hypertrophy in diabetes. (PMID: 14680844) Momiyama Y. … Matsuoka R. (Biochem. Biophys. Res. Commun. 2003) 3 48 67
- [The mitochondrial tRNA(Thr) A15951G mutation may be associated with Leber's hereditary optic neuropathy in two Chinese families]. (PMID: 21983721) Zhang Y. … Guan M.X. (Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2011) 3
- Comprehensive analysis of common mitochondrial DNA variants and colorectal cancer risk. (PMID: 19050702) Webb E. … Houlston R.S. (Br. J. Cancer 2008) 3
- Parkinson Disease Overview (PMID: 20301402) Pagon R.A. … Stephens K. ( 1993) 3
- Mitochondrial Disorders Overview (PMID: 20301403) Pagon R.A. … Stephens K. ( 1993) 3
Products for MT-TT Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Browse OriGene Antibodies
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for MT-TT
- Origene Custom Protein Services for MT-TT
- Browse OriGene Inhibitory RNA Products For MT-TT
- Browse OriGene qPCR primer pairs and template standards
- Browse CRISPR knockouts for MT-TT
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- GenScript: Custom all cDNA clones Services for MT-TT
- GenScript Custom Purified and Recombinant Proteins Services for MT-TT
- GenScript Custom Assay Services for MT-TT
- GenScript Custom overexpressing Cell Line Services for MT-TT
- Browse GenScript CRISPR for MT-TT
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for MT-TT
- Search ViGene Biosciences for MT-TT
- Search ViGene Biosciences for MT-TT
- Search ViGene Biosciences for MT-TT
- Search ViGene Biosciences for MT-TT
Sources for MT-TT Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) I2D
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) UniGene
- (28) AceView
- (29) RNAdb
- (30) ASD
- (31) ECgene
- (32) GeneAnnot
- (33) SAGE
- (34) SOURCE
- (35) HomoloGene
- (36) PanEnsembl
- (37) euGenes
- (38) SGD
- (39) FlyBase
- (40) WormBase
- (41) Pseudogene
- (42) DGV
- (43) dbSNP
- (44) HapMap
- (45) GenAtlas
- (46) GeneTests
- (47) HGMD
- (48) GAD
- (49) LSDB
- (50) BGMUT
- (51) HuGE
- (52) eBioscience
- (53) Atlas
- (54) Cell Signaling Technology
- (55) GenBank
- (56) H-invDB
- (57) HORDE
- (58) HUGE
- (59) IMGT
- (60) Leiden
- (61) MILLIPORE
- (62) miRBase
- (63) DME
- (64) Nature
- (65) NCBI
- (66) OriGene
- (67) PubMed
- (68) R&D Systems
- (69) Salk
- (70) TGDB
- (71) Tufts
- (72) YEDA
- (73) CROW21
- (74) Tocris
- (75) Abcam
- (76) Novus
- (77) ProSpec
- (78) Sino Biological
- (79) GenScript
- (80) Qiagen
- (81) Cloud-Clone Corp.
- (82) Enzo Life Sciences
- (83) OCA
- (84) Proteopedia
- (85) MOPED
- (86) SPIRE
- (87) neXtProt
- (88) Reactome
- (89) GeneGo (Thomson Reuters)
- (90) fRNAdb
- (91) DISEASES
- (92) SIMAP
- (93) GenomeRNAi
- (94) LifeMap
- (95) miRTarBase
- (96) MalaCards
- (97) Invitrogen
- (98) BitterDB
- (99) Vector BioLabs
- (100) ESI-BIO
- (101) RefSeq
- (102) BioSystems
- (103) MaxQB
- (104) IUPHAR
- (105) BioGPS
- (106) Illumina
- (107) COMPARTMENTS
- (108) HOMER
- (109) PaxDb
- (110) ApexBio
- (111) Addgene
- (112) Advanced Cell Diagnostics
- (113) antibodies-online
- (114) CYP
- (115) NONCODE
- (116) SwitchGear Genomics
- (117) TreeFam
- (118) PathCards
- (119) GeneReviews
- (120) GeneTex
- (121) Taconic Biosciences
- (122) GTEx
- (123) ProteomicsDB
- (124) SCBT
- (125) DGIdb
- (126) ClinicalTrials
- (127) FDA Approved Drugs
- (128) RVIS
- (129) SIGNOR
- (130) diseasecard
- (131) NIH Rare Diseases
- (132) Orphanet
- (133) UMLS
- (134) GTR
- (135) Disease Ontology
- (136) Genetics Home Reference
- (137) MeSH
- (138) MedlinePlus
- (139) CDC
- (140) NINDS
- (141) NCBI Bookshelf
- (142) ClinVar
- (143) Gene Damage Index
- (144) ViGene Biosciences
- (145) HPO
- (146) UDN
- (147) VISTA
- (148) FANTOM5
- (149) ENCODE
- (150) ProSci
- (151) Horizon