Aliases for MT-TR Gene
Subcategory (RNA class) for MT-TR Gene
non-coding RNA
Quality Score for this RNA gene is
3
Aliases for MT-TR Gene
External Ids for MT-TR Gene
- HGNC: 7496
- Entrez Gene: 4573
- Ensembl: ENSG00000210174
- OMIM: 590005
Previous HGNC Symbols for MT-TR Gene
- MTTR
Previous GeneCards Identifiers for MT-TR Gene
- GC00U921611
Summaries for MT-TR Gene
GeneCards Summary for MT-TR Gene
MT-TR (Mitochondrially Encoded TRNA Arginine) is an RNA Gene, and is affiliated with the non-coding RNA class. Diseases associated with MT-TR include Mitochondrial Disorders and Amyloidosis, Hereditary, Transthyretin-Related. Among its related pathways are tRNA Aminoacylation.
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MT-TR Gene
Genomics for MT-TR Gene
Regulatory Element Products
Genomic Location for MT-TR Gene
- Chromosome:
- MT
- Start:
- 10,405 bp from pter
- End:
- 10,469 bp from pter
- Size:
- 65 bases
- Orientation:
- Plus strand
Genomic View for MT-TR Gene
RefSeq DNA sequence for MT-TR Gene
No data available for Regulatory Elements for MT-TR Gene
Proteins for MT-TR Gene
Post-translational modifications for MT-TR Gene
No Post-translational modifications
Antibody Products
- Search GeneTex for Antibodies for MT-TR
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for MT-TR
- Origene Custom Protein Services for MT-TR
- Search GeneTex for Proteins for MT-TR
No data available for DME Specific Peptides for MT-TR Gene
Domains & Families for MT-TR Gene
Gene Families for MT-TR Gene
Graphical View of Domain Structure for InterPro Entry
No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MT-TR Gene
Function for MT-TR Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for MT-TR
-
- Search ViGene Biosciences for MT-TR
CRISPR Products
- Browse CRISPR knockouts for MT-TR
miRNA Products
- Search ViGene Biosciences for MT-TR
Inhibitory RNA Products
- Search ViGene Biosciences for MT-TR
Clone Products
- GenScript: Custom all cDNA clones Services for MT-TR
- VectorBuilder custom plasmid, inducible vectors for MT-TR
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MT-TR
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MT-TR Gene
Localization for MT-TR Gene
| Compartment | Confidence |
|---|---|
| mitochondrion | 2 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for MT-TR Gene
Pathways & Interactions for MT-TR Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | tRNA Aminoacylation | ||
Pathways by source for MT-TR Gene
1 KEGG pathway for MT-TR Gene
Interacting Proteins for MT-TR Gene
No data available for SIGNOR curated interactions for MT-TR Gene
Transcripts for MT-TR Gene
mRNA/cDNA for MT-TR Gene
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
- Browse CRISPR knockouts for MT-TR
miRNA Products
- Search ViGene Biosciences for MT-TR
Inhibitory RNA Products
- Search ViGene Biosciences for MT-TR
Clone Products
- GenScript: Custom all cDNA clones Services for MT-TR
- VectorBuilder custom plasmid, inducible vectors for MT-TR
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MT-TR
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Expression for MT-TR Gene
Primer Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MT-TR Gene
Orthologs for MT-TR Gene
No data available for Orthologs for MT-TR Gene
Paralogs for MT-TR Gene
No data available for Paralogs for MT-TR Gene
Variants for MT-TR Gene
Relevant External Links for MT-TR Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MT-TR Gene
Disorders for MT-TR Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| mitochondrial disorders |
|
|
| amyloidosis, hereditary, transthyretin-related |
|
|
Search MT-TR in MalaCards
View complete list of genes associated with diseases
Relevant External Links for MT-TR
- Genetic Association Database (GAD)
- MT-TR
No data available for UniProtKB/Swiss-Prot and Genatlas for MT-TR Gene
Publications for MT-TR Gene
- Molecular epidemiology of childhood mitochondrial encephalomyopathies in a Finnish population: sequence analysis of entire mtDNA of 17 children reveals heteroplasmic mutations in tRNAArg, tRNAGlu, and tRNALeu(UUR) genes. (PMID: 15286228) Uusimaa J. … Majamaa K. (Pediatrics 2004) 3 46 64
- Genetic polymorphisms of methylenetetrahydrofolate reductase (MTHFR) and methionine synthase reductase (MTRR) in ethnic populations in Texas; a report of a novel MTHFR polymorphic site, G1793A. (PMID: 11807892) Rady P.L. … Matalon R.K. (Am. J. Med. Genet. 2002) 3 46 64
- A novel mitochondrial tRNA Arg mutation resulting in an anticodon swap in a patient with mitochondrial encephalomyopathy. (PMID: 22781096) Roos S. … Oldfors A. (Eur. J. Hum. Genet. 2013) 3 64
- MtSNPscore: a combined evidence approach for assessing cumulative impact of mitochondrial variations in disease. (PMID: 19758471) Bhardwaj A. … Tiwari S. (BMC Bioinformatics 2009) 3 64
- Comprehensive analysis of common mitochondrial DNA variants and colorectal cancer risk. (PMID: 19050702) Webb E. … Houlston R.S. (Br. J. Cancer 2008) 3 64
Products for MT-TR Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for MT-TR
- Origene Custom Protein Services for MT-TR
- Browse OriGene Inhibitory RNA Products For MT-TR
- Browse OriGene qPCR primer pairs and template standards
- Browse CRISPR knockouts for MT-TR
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For MT-TR
- GenScript: Custom all cDNA clones Services for MT-TR
- GenScript Custom Purified and Recombinant Proteins Services for MT-TR
- GenScript Custom Assay Services for MT-TR
- GenScript Custom overexpressing Cell Line Services for MT-TR
- Browse GenScript CRISPR for MT-TR
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for MT-TR
- Browse Sino Biological cDNA Clones
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Proteins
- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Search GeneTex for Antibodies for MT-TR
- Search GeneTex for Proteins for MT-TR
- Search ViGene Biosciences for MT-TR
- Cyagen custom Knockout/knockin (KOKI) mouse models for MT-TR
- VectorBuilder custom plasmid, inducible vectors for MT-TR
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MT-TR
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for MT-TR Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer