Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MT-TM Gene

Subcategory (RNA class) for MT-TM Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for MT-TM Gene

  • Mitochondrially Encoded TRNA Methionine 2 5
  • TRNA Methionine 2
  • TRNA 3
  • TRNM 3
  • MTTM 3

External Ids for MT-TM Gene

Previous HGNC Symbols for MT-TM Gene

  • MTTM

Previous GeneCards Identifiers for MT-TM Gene

  • GC00U921607

Summaries for MT-TM Gene

GeneCards Summary for MT-TM Gene

MT-TM (Mitochondrially Encoded TRNA Methionine) is an RNA Gene, and is affiliated with the non-coding RNA class. Diseases associated with MT-TM include Mitochondrial Myopathy and Mitochondrial Disorders. Among its related pathways are tRNA Aminoacylation.

Additional gene information for MT-TM Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MT-TM Gene

Genomics for MT-TM Gene

Genomic Locations for MT-TM Gene

Genomic Locations for MT-TM Gene
chrMT:4,402-4,469
(GRCh38/hg38)
Size:
68 bases
Orientation:
Plus strand
chrMT:4,402-4,469
(GRCh37/hg19)

Genomic View for MT-TM Gene

Genes around MT-TM on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for MT-TM Gene

No data available for GeneHancer (GH) Regulatory Elements for MT-TM Gene

Proteins for MT-TM Gene

Post-translational modifications for MT-TM Gene

No Post-translational modifications

No data available for DME Specific Peptides for MT-TM Gene

Domains & Families for MT-TM Gene

Gene Families for MT-TM Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MT-TM: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MT-TM Gene

Function for MT-TM Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MT-TM Gene

Localization for MT-TM Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MT-TM gene
Compartment Confidence
mitochondrion 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MT-TM Gene

Pathways & Interactions for MT-TM Gene

SuperPathways for MT-TM Gene

SuperPathway Contained pathways
1 tRNA Aminoacylation
genes like me logo Genes that share pathways with MT-TM: view

Pathways by source for MT-TM Gene

1 KEGG pathway for MT-TM Gene

Interacting Proteins for MT-TM Gene

Gene Ontology (GO) - Biological Process for MT-TM Gene

None

No data available for SIGNOR curated interactions for MT-TM Gene

Drugs & Compounds for MT-TM Gene

No Compound Related Data Available

Transcripts for MT-TM Gene

mRNA/cDNA for MT-TM Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MT-TM Gene

No ASD Table

Relevant External Links for MT-TM Gene

GeneLoc Exon Structure for
MT-TM
ECgene alternative splicing isoforms for
MT-TM

Expression for MT-TM Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MT-TM Gene

mRNA differential expression in normal tissues according to GTEx for MT-TM Gene

This gene is overexpressed in Heart - Left Ventricle (x8.0), Brain - Putamen (basal ganglia) (x5.1), and Brain - Caudate (basal ganglia) (x4.3).
genes like me logo Genes that share expression patterns with MT-TM: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MT-TM Gene

Orthologs for MT-TM Gene

Evolution for MT-TM Gene

ENSEMBL:
Gene Tree for MT-TM (if available)
TreeFam:
Gene Tree for MT-TM (if available)

No data available for Orthologs for MT-TM Gene

Paralogs for MT-TM Gene

No data available for Paralogs for MT-TM Gene

Variants for MT-TM Gene

Additional Variant Information for MT-TM Gene

Human Gene Mutation Database (HGMD)
MT-TM
SNPedia medical, phenotypic, and genealogical associations of SNPs for
MT-TM

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MT-TM Gene

Disorders for MT-TM Gene

MalaCards: The human disease database

(2) MalaCards diseases for MT-TM Gene - From: ClinVar, GTR, and DISEASES

Disorder Aliases PubMed IDs
mitochondrial myopathy
  • mitochondrial cytopathy
mitochondrial disorders
  • mitochondrial encephalomyopathies
- elite association - COSMIC cancer census association via MalaCards
Search MT-TM in MalaCards View complete list of genes associated with diseases
genes like me logo Genes that share disorders with MT-TM: view

No data available for UniProtKB/Swiss-Prot , Genatlas and External Links for MT-TM Gene

Publications for MT-TM Gene

  1. Molecular characterization of mitochondrial transferRNAGln and transferRNAMet A4401G mutations in a Chinese family with hypertension. (PMID: 28259969) Yu SS … He ZF (Molecular medicine reports 2017) 3 58
  2. The mitochondrial tRNA(Met) 4454T > C variant may not be associated with essential hypertension in Han Chinese population. (PMID: 23627313) Wang Y … Shang X (Mitochondrial DNA 2014) 3 58
  3. Mitochondrial tRNAMet mutation is associated with clinical and biochemical characteristics in primary hypertension. (PMID: 23563319) Lu CQ … Xu QF (Molecular medicine reports 2013) 3 58
  4. The tRNAMet 4435A>G mutation in the mitochondrial haplogroup G2a1 is responsible for maternally inherited hypertension in a Chinese pedigree. (PMID: 21694735) Lu Z … Guan MX (European journal of human genetics : EJHG 2011) 3 58
  5. The human mitochondrial tRNAMet: structure/function relationship of a unique modification in the decoding of unconventional codons. (PMID: 21168417) Bilbille Y … Agris PF (Journal of molecular biology 2011) 3 58

Products for MT-TM Gene

Sources for MT-TM Gene

Content
Loading form....