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Aliases for MT-TL2 Gene

Subcategory (RNA class) for MT-TL2 Gene


Quality Score for this RNA gene is


Aliases for MT-TL2 Gene

  • Mitochondrially Encoded TRNA Leucine 2 (CUN) 2
  • TRNA Leucine 2 (CUN) 2
  • TRNL2 3
  • MTTL2 3
  • TRNA 3

External Ids for MT-TL2 Gene

Previous Symbols for MT-TL2 Gene

  • MTTL2

Summaries for MT-TL2 Gene

GeneCards Summary for MT-TL2 Gene

MT-TL2 (Mitochondrially Encoded TRNA Leucine 2 (CUN)) is a RNA Gene, and belongs to Mt_tRNA RNA class. Diseases associated with MT-TL2 include chronic progressive external ophthalmoplegia and mitochondrial disorders. Among its related pathways are tRNA Aminoacylation.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MT-TL2 Gene

Genomics for MT-TL2 Gene

Genomic Location for MT-TL2 Gene

12,266 bp from pter
12,336 bp from pter
71 bases
Plus strand

Genomic View for MT-TL2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:

RefSeq DNA sequence for MT-TL2 Gene

No data available for Regulatory Elements for MT-TL2 Gene

Proteins for MT-TL2 Gene

Post-translational modifications for MT-TL2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MT-TL2 Gene

Domains for MT-TL2 Gene

Gene Families for MT-TL2 Gene

  • MTTRNA :ncRNAs / Transfer RNA, mitochondrial
genes like me logo Genes that share domains with MT-TL2: view

No data available for Protein Domains and UniProtKB/Swiss-Prot for MT-TL2 Gene

Function for MT-TL2 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MT-TL2 Gene

Localization for MT-TL2 Gene

No data available for Gene Ontology (GO) - Cellular Components for MT-TL2 Gene

Pathways for MT-TL2 Gene

SuperPathways for MT-TL2 Gene

Superpath Contained pathways
1 tRNA Aminoacylation
genes like me logo Genes that share pathways with MT-TL2: view

Pathways by source for MT-TL2 Gene

1 KEGG pathway for MT-TL2 Gene

Interacting Proteins for MT-TL2 Gene

Gene Ontology (GO) - Biological Process for MT-TL2 Gene


Transcripts for MT-TL2 Gene

mRNA/cDNA for MT-TL2 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MT-TL2 Gene

No ASD Table

Relevant External Links for MT-TL2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MT-TL2 Gene

mRNA expression in normal human tissues for MT-TL2 Gene

mRNA differential expression in normal tissues according to GTEx for MT-TL2 Gene

This gene is overexpressed in Brain - Caudate (basal ganglia) (6.5), Brain - Putamen (basal ganglia) (6.5), and Brain - Substantia nigra (5.8).
genes like me logo Genes that share expressions with MT-TL2: view

Orthologs for MT-TL2 Gene

Evolution for MT-TL2 Gene

Gene Tree for MT-TL2 (if available)
Gene Tree for MT-TL2 (if available)

No data available for Orthologs for MT-TL2 Gene

Paralogs for MT-TL2 Gene

No data available for Paralogs for MT-TL2 Gene

Variants for MT-TL2 Gene

Relevant External Links for MT-TL2 Gene

HapMap Linkage Disequilibrium report
Human Gene Mutation Database (HGMD)

No data available for Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for MT-TL2 Gene

Disorders for MT-TL2 Gene

Relevant External Links for MT-TL2

genes like me logo Genes that share disorders with MT-TL2: view

No data available for UniProtKB/Swiss-Prot for MT-TL2 Gene

Publications for MT-TL2 Gene

  1. Genotyping Parkinson disease-associated mitochondrial polymorphisms. (PMID: 15931342) Jiang Y. … Greenlee A.R. (Clin Med Res 2004) 3
  2. Increased risk of oral cancer in relation to common Indian mitochondrial polymorphisms and Autosomal GSTP1 locus. (PMID: 17886251) Datta S. … Roy B. (Cancer 2007) 3
  3. Chronic progressive external ophthalmoplegia: a new heteroplasmic tRNA(Leu(CUN)) mutation of mitochondrial DNA. (PMID: 18603265) Cardaioli E. … Federico A. (J. Neurol. Sci. 2008) 3
  4. Mitochondrial DNA variant interactions modify breast cancer risk. (PMID: 18709563) Covarrubias D. … Leal S.M. (J. Hum. Genet. 2008) 3
  5. Comprehensive analysis of common mitochondrial DNA variants and colorectal cancer risk. (PMID: 19050702) Webb E. … Houlston R.S. (Br. J. Cancer 2008) 3

Products for MT-TL2 Gene

Sources for MT-TL2 Gene

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