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Aliases for MT-TK Gene

Subcategory (RNA class) for MT-TK Gene

Mt_tRNA

Quality Score for this RNA gene is

3

Aliases for MT-TK Gene

  • Mitochondrially Encoded TRNA Lysine 2
  • TRNA Lysine 2
  • MTTK 3
  • TRNA 3
  • TRNK 3

External Ids for MT-TK Gene

Previous Symbols for MT-TK Gene

  • MERRF
  • MTTK

Summaries for MT-TK Gene

GeneCards Summary for MT-TK Gene

MT-TK (Mitochondrially Encoded TRNA Lysine) is a RNA Gene, and belongs to Mt_tRNA RNA class. Diseases associated with MT-TK include merrf/melas overlap syndrome and mood disorder. Among its related pathways are tRNA Aminoacylation.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MT-TK Gene

Genomics for MT-TK Gene

Genomic Location for MT-TK Gene

Start:
8,295 bp from pter
End:
8,364 bp from pter
Size:
70 bases
Orientation:
Plus strand

Genomic View for MT-TK Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:

RefSeq DNA sequence for MT-TK Gene

No data available for Regulatory Elements for MT-TK Gene

Proteins for MT-TK Gene

Post-translational modifications for MT-TK Gene

No Post-translational modifications

No data available for DME Specific Peptides for MT-TK Gene

Domains for MT-TK Gene

Gene Families for MT-TK Gene

HGNC:
  • MTTRNA :ncRNAs / Transfer RNA, mitochondrial
genes like me logo Genes that share domains with MT-TK: view

No data available for Protein Domains and UniProtKB/Swiss-Prot for MT-TK Gene

Function for MT-TK Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MT-TK Gene

Localization for MT-TK Gene

No data available for Gene Ontology (GO) - Cellular Components for MT-TK Gene

Pathways for MT-TK Gene

SuperPathways for MT-TK Gene

Superpath Contained pathways
1 tRNA Aminoacylation
genes like me logo Genes that share pathways with MT-TK: view

Pathways by source for MT-TK Gene

1 KEGG pathway for MT-TK Gene

Interacting Proteins for MT-TK Gene

Gene Ontology (GO) - Biological Process for MT-TK Gene

None

Transcripts for MT-TK Gene

mRNA/cDNA for MT-TK Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MT-TK Gene

No ASD Table

Relevant External Links for MT-TK Gene

GeneLoc Exon Structure for
MT-TK
ECgene alternative splicing isoforms for
MT-TK

Expression for MT-TK Gene

mRNA expression in normal human tissues for MT-TK Gene

genes like me logo Genes that share expressions with MT-TK: view

Orthologs for MT-TK Gene

Evolution for MT-TK Gene

ENSEMBL:
Gene Tree for MT-TK (if available)
TreeFam:
Gene Tree for MT-TK (if available)

No data available for Orthologs for MT-TK Gene

Paralogs for MT-TK Gene

No data available for Paralogs for MT-TK Gene

Variants for MT-TK Gene

Relevant External Links for MT-TK Gene

HapMap Linkage Disequilibrium report
MT-TK
Human Gene Mutation Database (HGMD)
MT-TK

No data available for Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for MT-TK Gene

Disorders for MT-TK Gene

Relevant External Links for MT-TK

GeneTests
MT-TK
GeneReviews
MT-TK
Genetic Association Database (GAD)
MT-TK
genes like me logo Genes that share disorders with MT-TK: view

No data available for UniProtKB/Swiss-Prot for MT-TK Gene

Publications for MT-TK Gene

  1. Investigation on mitochondrial tRNA(Leu/Lys), NDI and ATPase 6/8 in Iranian multiple sclerosis patients. (PMID: 17619138) Ahari S.E. … Bahar M.A. (Cell. Mol. Neurobiol. 2007) 3 49
  2. Diagnostic screening of mitochondrial DNA mutations in Australian adults 1990-2001. (PMID: 14748908) Marotta R. … Collins S. (Intern Med J 2004) 3 49
  3. Detection of common disease-causing mutations in mitochondrial DNA (mitochondrial encephalomyopathy, lactic acidosis with stroke-like episodes MTTL1 3243 A>G and myoclonic epilepsy associated with ragged-red fibers MTTK 8344A>G) by real-time polymerase chain reaction. (PMID: 16645216) Fan H. … Farber R.A. (J Mol Diagn 2006) 3 49
  4. Common mitochondrial DNA and POLG1 mutations are rare in the Chinese patients with adult-onset ataxia on Taiwan. (PMID: 17300808) Lee Y.C. … Soong B.W. (J. Neurol. Sci. 2007) 3 49
  5. Sporadic myopathy and exercise intolerance associated with the mitochondrial 8328G>A tRNALys mutation. (PMID: 17410322) Blakely E.L. … Taylor R.W. (J. Neurol. 2007) 3

Products for MT-TK Gene

Sources for MT-TK Gene

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