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Aliases for MT-TI Gene

Subcategory (RNA class) for MT-TI Gene

non-coding RNA

Quality Score for this RNA gene is


Aliases for MT-TI Gene

  • Mitochondrially Encoded TRNA Isoleucine 2 5
  • TRNA Isoleucine 2
  • TRNA 3
  • TRNI 3
  • MTTI 3

External Ids for MT-TI Gene

Previous HGNC Symbols for MT-TI Gene

  • MTTI

Previous GeneCards Identifiers for MT-TI Gene

  • GC00U921603

Summaries for MT-TI Gene

GeneCards Summary for MT-TI Gene

MT-TI (Mitochondrially Encoded TRNA Isoleucine) is an RNA Gene, and is affiliated with the non-coding RNA class. Diseases associated with MT-TI include Hypomagnesemia, Hypertension, And Hypercholesterolemia, Mitochondrial and Myoclonic Epilepsy Associated With Ragged-Red Fibers. Among its related pathways are tRNA Aminoacylation.

Additional gene information for MT-TI Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MT-TI Gene

Genomics for MT-TI Gene

Genomic Locations for MT-TI Gene

Genomic Locations for MT-TI Gene
69 bases
Plus strand

Genomic View for MT-TI Gene

Genes around MT-TI on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for MT-TI Gene

No data available for GeneHancer (GH) Regulatory Elements for MT-TI Gene

Proteins for MT-TI Gene

Post-translational modifications for MT-TI Gene

No Post-translational modifications

No data available for DME Specific Peptides for MT-TI Gene

Domains & Families for MT-TI Gene

Gene Families for MT-TI Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MT-TI: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MT-TI Gene

Function for MT-TI Gene

Human Phenotype Ontology for MT-TI Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MT-TI Gene

Localization for MT-TI Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MT-TI gene
Compartment Confidence
mitochondrion 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MT-TI Gene

Pathways & Interactions for MT-TI Gene

SuperPathways for MT-TI Gene

SuperPathway Contained pathways
1 tRNA Aminoacylation
genes like me logo Genes that share pathways with MT-TI: view

Pathways by source for MT-TI Gene

1 KEGG pathway for MT-TI Gene

Interacting Proteins for MT-TI Gene

Gene Ontology (GO) - Biological Process for MT-TI Gene


No data available for SIGNOR curated interactions for MT-TI Gene

Drugs & Compounds for MT-TI Gene

No Compound Related Data Available

Transcripts for MT-TI Gene

mRNA/cDNA for MT-TI Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MT-TI Gene

No ASD Table

Relevant External Links for MT-TI Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MT-TI Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MT-TI Gene

Orthologs for MT-TI Gene

Evolution for MT-TI Gene

Gene Tree for MT-TI (if available)
Gene Tree for MT-TI (if available)

No data available for Orthologs for MT-TI Gene

Paralogs for MT-TI Gene

No data available for Paralogs for MT-TI Gene

Variants for MT-TI Gene

Additional Variant Information for MT-TI Gene

Human Gene Mutation Database (HGMD)
SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MT-TI Gene

Disorders for MT-TI Gene

MalaCards: The human disease database

(5) MalaCards diseases for MT-TI Gene - From: HGMD, ClinVar, GTR, DISEASES, and GeneCards

- elite association - COSMIC cancer census association via MalaCards
Search MT-TI in MalaCards View complete list of genes associated with diseases

Additional Disease Information for MT-TI

Genetic Association Database
genes like me logo Genes that share disorders with MT-TI: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MT-TI Gene

Publications for MT-TI Gene

  1. [Search for mitochondrial DNA T4291C mutation in Hungarian patients with metabolic syndrome]. (PMID: 16734181) Maász A … Melegh B (Orvosi hetilap 2006) 3 44 58
  2. [Mitochondrial DNA mutation associated with hypertension in tRNA(Ile) and tRNA(Gln) genes]. (PMID: 25297595) Zhu C … Li Y (Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics 2014) 3 58
  3. Molecular characterization of a Chinese family carrying a novel C4329A mutation in mitochondrial tRNAIle and tRNAGln genes. (PMID: 25056089) Liu Y … Chen Y (BMC medical genetics 2014) 3 58
  4. Novel mitochondrial tRNA(Ile) m.4282A>G gene mutation leads to chronic progressive external ophthalmoplegia plus phenotype. (PMID: 25034047) Jackson CB … Schaller A (The British journal of ophthalmology 2014) 3 58
  5. The amyloid-β-SDR5C1(ABAD) interaction does not mediate a specific inhibition of mitochondrial RNase P. (PMID: 23755257) Vilardo E … Rossmanith W (PloS one 2013) 3 58

Products for MT-TI Gene

Sources for MT-TI Gene

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