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Aliases for MT-TH Gene

Subcategory (RNA class) for MT-TH Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for MT-TH Gene

  • Mitochondrially Encoded TRNA Histidine 2 5
  • TRNA Histidine 2
  • TRNA 3
  • TRNH 3
  • MTTH 3

External Ids for MT-TH Gene

Previous HGNC Symbols for MT-TH Gene

  • MTTH

Previous GeneCards Identifiers for MT-TH Gene

  • GC00U921602

Summaries for MT-TH Gene

GeneCards Summary for MT-TH Gene

MT-TH (Mitochondrially Encoded TRNA Histidine) is an RNA Gene, and is affiliated with the non-coding RNA class. Diseases associated with MT-TH include mitochondrial non-syndromic sensorineural deafness and merrf syndrome. Among its related pathways are tRNA Aminoacylation.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MT-TH Gene

Genomics for MT-TH Gene

Genomic Location for MT-TH Gene

Chromosome:
MT
Start:
12,138 bp from pter
End:
12,206 bp from pter
Size:
69 bases
Orientation:
Plus strand

Genomic View for MT-TH Gene

Genes around MT-TH on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for MT-TH Gene

No data available for Regulatory Elements for MT-TH Gene

Proteins for MT-TH Gene

Post-translational modifications for MT-TH Gene

No Post-translational modifications

No data available for DME Specific Peptides for MT-TH Gene

Domains & Families for MT-TH Gene

Gene Families for MT-TH Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MT-TH: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MT-TH Gene

Function for MT-TH Gene

Human Phenotype Ontology for MT-TH Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MT-TH Gene

Localization for MT-TH Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for MT-TH Gene COMPARTMENTS Subcellular localization image for MT-TH gene
Compartment Confidence
chloroplast 3
mitochondrion 2
nucleus 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for MT-TH Gene

Pathways & Interactions for MT-TH Gene

SuperPathways for MT-TH Gene

Superpath Contained pathways
1 tRNA Aminoacylation
genes like me logo Genes that share pathways with MT-TH: view

Pathways by source for MT-TH Gene

1 KEGG pathway for MT-TH Gene

Interacting Proteins for MT-TH Gene

Gene Ontology (GO) - Biological Process for MT-TH Gene

None

No data available for SIGNOR curated interactions for MT-TH Gene

Drugs & Compounds for MT-TH Gene

No Compound Related Data Available

Transcripts for MT-TH Gene

mRNA/cDNA for MT-TH Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MT-TH Gene

No ASD Table

Relevant External Links for MT-TH Gene

GeneLoc Exon Structure for
MT-TH
ECgene alternative splicing isoforms for
MT-TH

Expression for MT-TH Gene

mRNA expression in normal human tissues for MT-TH Gene

genes like me logo Genes that share expression patterns with MT-TH: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MT-TH Gene

Orthologs for MT-TH Gene

Evolution for MT-TH Gene

ENSEMBL:
Gene Tree for MT-TH (if available)
TreeFam:
Gene Tree for MT-TH (if available)

No data available for Orthologs for MT-TH Gene

Paralogs for MT-TH Gene

No data available for Paralogs for MT-TH Gene

Variants for MT-TH Gene

Relevant External Links for MT-TH Gene

HapMap Linkage Disequilibrium report
MT-TH
Human Gene Mutation Database (HGMD)
MT-TH

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MT-TH Gene

Disorders for MT-TH Gene

MalaCards: The human disease database

(6) MalaCards diseases for MT-TH Gene - From: GeneTests and Orphanet

Disorder Aliases PubMed IDs
mitochondrial non-syndromic sensorineural deafness
  • isolated mitochondrial neurosensory deafness
merrf syndrome
  • fukuhara syndrome
melas, mt-th-related
merrf/melas overlap syndrome
mitochondrial disorders
  • mitochondrial encephalomyopathies
- elite association - COSMIC cancer census association via MalaCards
Search MT-TH in MalaCards View complete list of genes associated with diseases
genes like me logo Genes that share disorders with MT-TH: view

No data available for UniProtKB/Swiss-Prot , Genatlas and External Links for MT-TH Gene

Publications for MT-TH Gene

  1. Two novel mutations in COII and tRNA(His) mitochondrial genes in asthenozoospermic infertiles men. (PMID: 24931671) Siwar B.G. … Leila A.K. (Biochem. Biophys. Res. Commun. 2014) 3 67
  2. A deafness-associated tRNAHis mutation alters the mitochondrial function, ROS production and membrane potential. (PMID: 24920829) Gong S. … Guan M.X. (Nucleic Acids Res. 2014) 3
  3. MtSNPscore: a combined evidence approach for assessing cumulative impact of mitochondrial variations in disease. (PMID: 19758471) Bhardwaj A. … Tiwari S. (BMC Bioinformatics 2009) 3

Products for MT-TH Gene

Sources for MT-TH Gene

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