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Aliases for MT-TH Gene

Subcategory (RNA class) for MT-TH Gene

non-coding RNA

Quality Score for this RNA gene is


Aliases for MT-TH Gene

  • Mitochondrially Encoded TRNA Histidine 2 5
  • TRNA Histidine 2
  • TRNA 3
  • TRNH 3
  • MTTH 3

External Ids for MT-TH Gene

Previous HGNC Symbols for MT-TH Gene

  • MTTH

Previous GeneCards Identifiers for MT-TH Gene

  • GC00U921602

Summaries for MT-TH Gene

GeneCards Summary for MT-TH Gene

MT-TH (Mitochondrially Encoded TRNA Histidine) is an RNA Gene, and is affiliated with the non-coding RNA class. Diseases associated with MT-TH include Deafness, Nonsyndromic Sensorineural, Mitochondrial and Mitochondrial Non-Syndromic Sensorineural Deafness. Among its related pathways are tRNA Aminoacylation.

Additional gene information for MT-TH Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MT-TH Gene

Genomics for MT-TH Gene

Genomic Locations for MT-TH Gene

Genomic Locations for MT-TH Gene
69 bases
Plus strand

Genomic View for MT-TH Gene

Genes around MT-TH on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for MT-TH Gene

No data available for GeneHancer (GH) Regulatory Elements for MT-TH Gene

Proteins for MT-TH Gene

Post-translational modifications for MT-TH Gene

No Post-translational modifications

No data available for DME Specific Peptides for MT-TH Gene

Domains & Families for MT-TH Gene

Gene Families for MT-TH Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MT-TH: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MT-TH Gene

Function for MT-TH Gene

Human Phenotype Ontology for MT-TH Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MT-TH Gene

Localization for MT-TH Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MT-TH gene
Compartment Confidence
mitochondrion 2
nucleus 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MT-TH Gene

Pathways & Interactions for MT-TH Gene

SuperPathways for MT-TH Gene

SuperPathway Contained pathways
1 tRNA Aminoacylation
genes like me logo Genes that share pathways with MT-TH: view

Pathways by source for MT-TH Gene

1 KEGG pathway for MT-TH Gene

Interacting Proteins for MT-TH Gene

Gene Ontology (GO) - Biological Process for MT-TH Gene


No data available for SIGNOR curated interactions for MT-TH Gene

Drugs & Compounds for MT-TH Gene

No Compound Related Data Available

Transcripts for MT-TH Gene

mRNA/cDNA for MT-TH Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MT-TH Gene

No ASD Table

Relevant External Links for MT-TH Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MT-TH Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MT-TH Gene

Phenotype-based relationships between genes and organs from Gene ORGANizer for MT-TH Gene

Germ Layers:
  • ectoderm
  • endoderm
  • mesoderm
  • cardiovascular
  • digestive
  • endocrine
  • immune
  • integumentary
  • nervous
  • respiratory
  • skeletal muscle
  • urinary
Head and neck:
  • brain
  • cerebellum
  • cranial nerve
  • ear
  • eye
  • eyelid
  • face
  • head
  • inner ear
  • diaphragm
  • esophagus
  • heart
  • heart valve
  • lung
  • kidney
  • pancreas
  • stomach
  • blood
  • blood vessel
  • peripheral nerve
  • peripheral nervous system
  • skin
  • spinal cord
  • white blood cell
genes like me logo Genes that share expression patterns with MT-TH: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Evidence on tissue expression from TISSUES for MT-TH Gene

Orthologs for MT-TH Gene

Evolution for MT-TH Gene

Gene Tree for MT-TH (if available)
Gene Tree for MT-TH (if available)

No data available for Orthologs for MT-TH Gene

Paralogs for MT-TH Gene

No data available for Paralogs for MT-TH Gene

Variants for MT-TH Gene

Additional Variant Information for MT-TH Gene

Human Gene Mutation Database (HGMD)
SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MT-TH Gene

Disorders for MT-TH Gene

MalaCards: The human disease database

(6) MalaCards diseases for MT-TH Gene - From: HGMD, ClinVar, GTR, Orphanet, and DISEASES

- elite association - COSMIC cancer census association via MalaCards
Search MT-TH in MalaCards View complete list of genes associated with diseases
genes like me logo Genes that share disorders with MT-TH: view

No data available for UniProtKB/Swiss-Prot , Genatlas and External Links for MT-TH Gene

Publications for MT-TH Gene

  1. A deafness-associated tRNAHis mutation alters the mitochondrial function, ROS production and membrane potential. (PMID: 24920829) Gong S … Guan MX (Nucleic acids research 2014) 3 58
  2. Two novel mutations in COII and tRNA(His) mitochondrial genes in asthenozoospermic infertiles men. (PMID: 24931671) Siwar BG … Leila AK (Biochemical and biophysical research communications 2014) 3 58
  3. MtSNPscore: a combined evidence approach for assessing cumulative impact of mitochondrial variations in disease. (PMID: 19758471) Bhardwaj A … Tiwari S (BMC bioinformatics 2009) 3 58

Products for MT-TH Gene

Sources for MT-TH Gene

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