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Aliases for MT-TC Gene

Subcategory (RNA class) for MT-TC Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for MT-TC Gene

  • Mitochondrially Encoded TRNA Cysteine 2 5
  • TRNA Cysteine 2
  • TRNA 3
  • TRNC 3
  • MTTC 3

External Ids for MT-TC Gene

Previous HGNC Symbols for MT-TC Gene

  • MTTC

Previous GeneCards Identifiers for MT-TC Gene

  • GC00U921597

Summaries for MT-TC Gene

GeneCards Summary for MT-TC Gene

MT-TC (Mitochondrially Encoded TRNA Cysteine) is an RNA Gene, and is affiliated with the non-coding RNA class. Diseases associated with MT-TC include Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, And Stroke-Like Episodes and Mitochondrial Disorders. Among its related pathways are tRNA Aminoacylation.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MT-TC Gene

Genomics for MT-TC Gene

Genomic Location for MT-TC Gene

Chromosome:
MT
Start:
5,761 bp from pter
End:
5,826 bp from pter
Size:
66 bases
Orientation:
Minus strand

Genomic View for MT-TC Gene

Genes around MT-TC on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for MT-TC Gene

No data available for Regulatory Elements for MT-TC Gene

Proteins for MT-TC Gene

Post-translational modifications for MT-TC Gene

No Post-translational modifications

No data available for DME Specific Peptides for MT-TC Gene

Domains & Families for MT-TC Gene

Gene Families for MT-TC Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MT-TC: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MT-TC Gene

Function for MT-TC Gene

Human Phenotype Ontology for MT-TC Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MT-TC Gene

Localization for MT-TC Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MT-TC gene
Compartment Confidence
mitochondrion 2
nucleus 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for MT-TC Gene

Pathways & Interactions for MT-TC Gene

SuperPathways for MT-TC Gene

SuperPathway Contained pathways
1 tRNA Aminoacylation
genes like me logo Genes that share pathways with MT-TC: view

Pathways by source for MT-TC Gene

1 KEGG pathway for MT-TC Gene

Interacting Proteins for MT-TC Gene

Gene Ontology (GO) - Biological Process for MT-TC Gene

None

No data available for SIGNOR curated interactions for MT-TC Gene

Drugs & Compounds for MT-TC Gene

No Compound Related Data Available

Transcripts for MT-TC Gene

mRNA/cDNA for MT-TC Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MT-TC Gene

No ASD Table

Relevant External Links for MT-TC Gene

GeneLoc Exon Structure for
MT-TC
ECgene alternative splicing isoforms for
MT-TC

Expression for MT-TC Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MT-TC Gene

Orthologs for MT-TC Gene

Evolution for MT-TC Gene

ENSEMBL:
Gene Tree for MT-TC (if available)
TreeFam:
Gene Tree for MT-TC (if available)

No data available for Orthologs for MT-TC Gene

Paralogs for MT-TC Gene

No data available for Paralogs for MT-TC Gene

Variants for MT-TC Gene

Relevant External Links for MT-TC Gene

Human Gene Mutation Database (HGMD)
MT-TC
SNPedia medical, phenotypic, and genealogical associations of SNPs for
MT-TC

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MT-TC Gene

Disorders for MT-TC Gene

MalaCards: The human disease database

(7) MalaCards diseases for MT-TC Gene - From: ClinVar, GeneTests, DISEASES, and GeneCards

Disorder Aliases PubMed IDs
mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes
  • melas syndrome
mitochondrial disorders
  • mitochondrial encephalomyopathies
geniculate herpes zoster
  • geniculate neuralgia
trigeminal nerve disease
  • trigeminal nerve diseases
trigeminal neuralgia
  • trifacial neuralgia
- elite association - COSMIC cancer census association via MalaCards
Search MT-TC in MalaCards View complete list of genes associated with diseases
genes like me logo Genes that share disorders with MT-TC: view

No data available for UniProtKB/Swiss-Prot , Genatlas and External Links for MT-TC Gene

Publications for MT-TC Gene

  1. Point mutations in KAL1 and the mitochondrial gene MT-tRNA(cys) synergize to produce Kallmann syndrome phenotype. (PMID: 26278626) Wang F. … Sun F. (Sci Rep 2015) 3 64
  2. MtSNPscore: a combined evidence approach for assessing cumulative impact of mitochondrial variations in disease. (PMID: 19758471) Bhardwaj A. … Tiwari S. (BMC Bioinformatics 2009) 3 64
  3. Mitochondrial Disorders Overview (PMID: 20301403) Pagon R.A. … Stephens K. ( 1993) 3 64
  4. MELAS (PMID: 20301411) Pagon R.A. … Stephens K. ( 1993) 3 64

Products for MT-TC Gene

Sources for MT-TC Gene

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