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Aliases for MT-TA Gene

Subcategory (RNA class) for MT-TA Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for MT-TA Gene

  • Mitochondrially Encoded TRNA Alanine 2 5
  • TRNA 3 3
  • TRNA Alanine 2
  • MTTA 3

External Ids for MT-TA Gene

Previous HGNC Symbols for MT-TA Gene

  • MTTA

Previous GeneCards Identifiers for MT-TA Gene

  • GC00U921596

Summaries for MT-TA Gene

GeneCards Summary for MT-TA Gene

MT-TA (Mitochondrially Encoded TRNA Alanine) is an RNA Gene, and is affiliated with the non-coding RNA class. Diseases associated with MT-TA include Mitochondrial Disorders and Combined Oxidative Phosphorylation Deficiency 8. Among its related pathways are tRNA Aminoacylation.

Additional gene information for MT-TA Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MT-TA Gene

Genomics for MT-TA Gene

Genomic Locations for MT-TA Gene

Genomic Locations for MT-TA Gene
chrMT:5,587-5,655
(GRCh38/hg38)
Size:
69 bases
Orientation:
Minus strand
chrMT:5,587-5,655
(GRCh37/hg19)

Genomic View for MT-TA Gene

Genes around MT-TA on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for MT-TA Gene

No data available for Regulatory Elements for MT-TA Gene

Proteins for MT-TA Gene

Post-translational modifications for MT-TA Gene

No Post-translational modifications

No data available for DME Specific Peptides for MT-TA Gene

Domains & Families for MT-TA Gene

Gene Families for MT-TA Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MT-TA: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MT-TA Gene

Function for MT-TA Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MT-TA Gene

Localization for MT-TA Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MT-TA gene
Compartment Confidence
mitochondrion 2
nucleus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MT-TA Gene

Pathways & Interactions for MT-TA Gene

SuperPathways for MT-TA Gene

SuperPathway Contained pathways
1 tRNA Aminoacylation
genes like me logo Genes that share pathways with MT-TA: view

Pathways by source for MT-TA Gene

1 KEGG pathway for MT-TA Gene

Interacting Proteins for MT-TA Gene

Gene Ontology (GO) - Biological Process for MT-TA Gene

None

No data available for SIGNOR curated interactions for MT-TA Gene

Drugs & Compounds for MT-TA Gene

No Compound Related Data Available

Transcripts for MT-TA Gene

mRNA/cDNA for MT-TA Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MT-TA Gene

No ASD Table

Relevant External Links for MT-TA Gene

GeneLoc Exon Structure for
MT-TA
ECgene alternative splicing isoforms for
MT-TA

Expression for MT-TA Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MT-TA Gene

genes like me logo Genes that share expression patterns with MT-TA: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MT-TA Gene

Orthologs for MT-TA Gene

Evolution for MT-TA Gene

ENSEMBL:
Gene Tree for MT-TA (if available)
TreeFam:
Gene Tree for MT-TA (if available)

No data available for Orthologs for MT-TA Gene

Paralogs for MT-TA Gene

No data available for Paralogs for MT-TA Gene

Variants for MT-TA Gene

Relevant External Links for MT-TA Gene

Human Gene Mutation Database (HGMD)
MT-TA
SNPedia medical, phenotypic, and genealogical associations of SNPs for
MT-TA

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MT-TA Gene

Disorders for MT-TA Gene

MalaCards: The human disease database

(4) MalaCards diseases for MT-TA Gene - From: HGMD, ClinVar, GeneTests, DISEASES, and GeneCards

Disorder Aliases PubMed IDs
mitochondrial disorders
  • mitochondrial encephalomyopathies
combined oxidative phosphorylation deficiency 8
  • mitochondrial myopathies
chronic progressive external ophthalmoplegia
  • chronic progressive external ophthalmoplegia [ambiguous]
moebius syndrome
  • mobius syndrome
- elite association - COSMIC cancer census association via MalaCards
Search MT-TA in MalaCards View complete list of genes associated with diseases
genes like me logo Genes that share disorders with MT-TA: view

No data available for UniProtKB/Swiss-Prot , Genatlas and External Links for MT-TA Gene

Publications for MT-TA Gene

  1. AlaMetGln (PMID: 28111408) Xu Y … Liu W (International heart journal 2017) 3 60
  2. A Hypertension-Associated tRNAAla Mutation Alters tRNA Metabolism and Mitochondrial Function. (PMID: 27161322) Jiang P … Guan MX (Molecular and cellular biology 2016) 3 60
  3. Pathogenic mitochondrial mt-tRNA(Ala) variants are uniquely associated with isolated myopathy. (PMID: 25873012) Lehmann D … Taylor RW (European journal of human genetics : EJHG 2015) 3 60
  4. The mutations m.5628T>C and m.8348A>G in single muscle fibers of a patient with chronic progressive external ophthalmoplegia. (PMID: 22743145) Gamba J … Tengan CH (Journal of the neurological sciences 2012) 3 60
  5. MtSNPscore: a combined evidence approach for assessing cumulative impact of mitochondrial variations in disease. (PMID: 19758471) Bhardwaj A … Tiwari S (BMC bioinformatics 2009) 3 60

Products for MT-TA Gene

Sources for MT-TA Gene

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