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Aliases for MT-TA Gene

Subcategory (RNA class) for MT-TA Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for MT-TA Gene

  • Mitochondrially Encoded TRNA Alanine 2 5
  • TRNA 3 3
  • TRNA Alanine 2
  • MTTA 3

External Ids for MT-TA Gene

Previous HGNC Symbols for MT-TA Gene

  • MTTA

Previous GeneCards Identifiers for MT-TA Gene

  • GC00U921596

Summaries for MT-TA Gene

GeneCards Summary for MT-TA Gene

MT-TA (Mitochondrially Encoded TRNA Alanine) is an RNA Gene, and is affiliated with the non-coding RNA class. Diseases associated with MT-TA include Combined Oxidative Phosphorylation Deficiency 8 and Mitochondrial Disorders. Among its related pathways are tRNA Aminoacylation.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MT-TA Gene

Genomics for MT-TA Gene

Genomic Location for MT-TA Gene

Chromosome:
MT
Start:
5,587 bp from pter
End:
5,655 bp from pter
Size:
69 bases
Orientation:
Minus strand

Genomic View for MT-TA Gene

Genes around MT-TA on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for MT-TA Gene

No data available for Regulatory Elements for MT-TA Gene

Proteins for MT-TA Gene

Post-translational modifications for MT-TA Gene

No Post-translational modifications

No data available for DME Specific Peptides for MT-TA Gene

Domains & Families for MT-TA Gene

Gene Families for MT-TA Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MT-TA: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MT-TA Gene

Function for MT-TA Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MT-TA Gene

Localization for MT-TA Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MT-TA gene
Compartment Confidence
mitochondrion 2
nucleus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for MT-TA Gene

Pathways & Interactions for MT-TA Gene

SuperPathways for MT-TA Gene

SuperPathway Contained pathways
1 tRNA Aminoacylation
genes like me logo Genes that share pathways with MT-TA: view

Pathways by source for MT-TA Gene

1 KEGG pathway for MT-TA Gene

Interacting Proteins for MT-TA Gene

Gene Ontology (GO) - Biological Process for MT-TA Gene

None

No data available for SIGNOR curated interactions for MT-TA Gene

Transcripts for MT-TA Gene

mRNA/cDNA for MT-TA Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MT-TA Gene

No ASD Table

Relevant External Links for MT-TA Gene

GeneLoc Exon Structure for
MT-TA
ECgene alternative splicing isoforms for
MT-TA

Expression for MT-TA Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MT-TA Gene

genes like me logo Genes that share expression patterns with MT-TA: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MT-TA Gene

Orthologs for MT-TA Gene

Evolution for MT-TA Gene

ENSEMBL:
Gene Tree for MT-TA (if available)
TreeFam:
Gene Tree for MT-TA (if available)

No data available for Orthologs for MT-TA Gene

Paralogs for MT-TA Gene

No data available for Paralogs for MT-TA Gene

Variants for MT-TA Gene

Relevant External Links for MT-TA Gene

Human Gene Mutation Database (HGMD)
MT-TA
SNPedia medical, phenotypic, and genealogical associations of SNPs for
MT-TA

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MT-TA Gene

Disorders for MT-TA Gene

MalaCards: The human disease database

(4) MalaCards diseases for MT-TA Gene - From: ClinVar, GeneTests, DISEASES, and GeneCards

Disorder Aliases PubMed IDs
combined oxidative phosphorylation deficiency 8
  • mitochondrial myopathies
mitochondrial disorders
  • mitochondrial encephalomyopathies
chronic progressive external ophthalmoplegia
  • chronic progressive external ophthalmoplegia [ambiguous]
moebius syndrome
  • mobius syndrome
- elite association - COSMIC cancer census association via MalaCards
Search MT-TA in MalaCards View complete list of genes associated with diseases
genes like me logo Genes that share disorders with MT-TA: view

No data available for UniProtKB/Swiss-Prot , Genatlas and External Links for MT-TA Gene

Publications for MT-TA Gene

  1. The Mitochondrial tRNA(Ala) T5655C Mutation May Modulate the Phenotypic Expression of tRNA(Met) and tRNA(Gln) A4401G Mutation in a Han Chinese Family With Essential Hypertension. (PMID: 28111408) Xu Y. … Liu W. (Int Heart J 2017) 3 64
  2. Pathogenic mitochondrial mt-tRNA(Ala) variants are uniquely associated with isolated myopathy. (PMID: 25873012) Lehmann D. … Taylor R.W. (Eur. J. Hum. Genet. 2015) 3 64
  3. The mutations m.5628T>C and m.8348A>G in single muscle fibers of a patient with chronic progressive external ophthalmoplegia. (PMID: 22743145) Gamba J. … Tengan C.H. (J. Neurol. Sci. 2012) 3 64
  4. MtSNPscore: a combined evidence approach for assessing cumulative impact of mitochondrial variations in disease. (PMID: 19758471) Bhardwaj A. … Tiwari S. (BMC Bioinformatics 2009) 3 64
  5. Motor neuron disease in a patient with a mitochondrial tRNAIle mutation. (PMID: 16358336) Borthwick G.M. … Turnbull D.M. (Ann. Neurol. 2006) 3 64

Products for MT-TA Gene

Sources for MT-TA Gene

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