Subcategory (RNA class) for MT-RNR2 Gene
Quality Score for this RNA gene is
Aliases for MT-RNR2 Gene
External Ids for MT-RNR2 Gene
Previous HGNC Symbols for MT-RNR2 Gene
Previous GeneCards Identifiers for MT-RNR2 Gene
GeneCards Summary for MT-RNR2 Gene
MT-RNR2 (Mitochondrially Encoded 16S RNA) is an RNA Gene, and is affiliated with the Mt_rRNA class. Diseases associated with MT-RNR2 include chronic progressive external ophthalmoplegia and alzheimer disease. Among its related pathways are Ribosome biogenesis in eukaryotes and Apoptosis and survival_Regulation of Apoptosis by Mitochondrial Proteins.
UniProtKB/Swiss-Prot for MT-RNR2 Gene
Plays a role as a neuroprotective factor. Protects against death induced by multiple different familial Alzheimer disease genes and beta amyloid proteins in Alzheimer disease. Suppresses apoptosis by binding to BAX and preventing the translocation of BAX from the cytosol to mitochondria. Binds to IGFBP3 and specifically blocks IGFBP3-induced cell death Induces chemotaxis of mononuclear phagocytes via FPR2. Reduces the aggregation and fibrillary formation by suppressing the effect of APP on mononuclear phagocytes and acts by competitively inhibiting the access of FPRL1 to APP.